ZA945103B - Inhibition of phosphatidylinositol 3-kinase with Wortmannin and analogs thereof - Google Patents

Inhibition of phosphatidylinositol 3-kinase with Wortmannin and analogs thereof

Info

Publication number
ZA945103B
ZA945103B ZA945103A ZA945103A ZA945103B ZA 945103 B ZA945103 B ZA 945103B ZA 945103 A ZA945103 A ZA 945103A ZA 945103 A ZA945103 A ZA 945103A ZA 945103 B ZA945103 B ZA 945103B
Authority
ZA
South Africa
Prior art keywords
wortmannin
phosphatidylinositol
analogs
kinase
inhibition
Prior art date
Application number
ZA945103A
Other languages
English (en)
Inventor
Rosanne Bonjouklian
Garth Powis
Chris John Vlahos
Original Assignee
Lilly Co Eli
Univ Arizona
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli, Univ Arizona filed Critical Lilly Co Eli
Publication of ZA945103B publication Critical patent/ZA945103B/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365Lactones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Furan Compounds (AREA)
ZA945103A 1993-07-19 1994-07-13 Inhibition of phosphatidylinositol 3-kinase with Wortmannin and analogs thereof ZA945103B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/094,279 US5378725A (en) 1993-07-19 1993-07-19 Inhibition of phosphatidylinositol 3-kinase with wortmannin and analogs thereof

Publications (1)

Publication Number Publication Date
ZA945103B true ZA945103B (en) 1996-03-27

Family

ID=22244209

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA945103A ZA945103B (en) 1993-07-19 1994-07-13 Inhibition of phosphatidylinositol 3-kinase with Wortmannin and analogs thereof

Country Status (16)

Country Link
US (1) US5378725A (enExample)
EP (1) EP0635268A1 (enExample)
JP (1) JPH0753370A (enExample)
KR (1) KR950002755A (enExample)
CN (1) CN1111127A (enExample)
AU (1) AU678831B2 (enExample)
CA (1) CA2128046A1 (enExample)
CZ (1) CZ283806B6 (enExample)
HU (1) HUT67667A (enExample)
IL (1) IL110325A0 (enExample)
NO (1) NO942641L (enExample)
PH (1) PH30794A (enExample)
PL (1) PL304317A1 (enExample)
RU (1) RU94026082A (enExample)
TW (1) TW287102B (enExample)
ZA (1) ZA945103B (enExample)

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WO2006125539A2 (en) * 2005-05-27 2006-11-30 Bayer Healthcare Ag Combination therapy comprising diaryl ureas for treating diseases
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CN104774239B (zh) * 2015-03-13 2017-01-04 暨南大学 多节孢绿胶霉素类化合物及其用途
CN107058137B (zh) * 2017-06-14 2020-02-07 海正药业(杭州)有限公司 一种渥曼青霉及其生产渥曼青霉素的方法

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US4988682A (en) * 1989-02-03 1991-01-29 University Of Pittsburgh Myo-inositol analogs and method for their use
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Also Published As

Publication number Publication date
NO942641D0 (no) 1994-07-14
JPH0753370A (ja) 1995-02-28
HU9402128D0 (en) 1994-09-28
EP0635268A1 (en) 1995-01-25
CZ283806B6 (cs) 1998-06-17
CN1111127A (zh) 1995-11-08
PL304317A1 (en) 1995-01-23
TW287102B (enExample) 1996-10-01
KR950002755A (ko) 1995-02-16
PH30794A (en) 1997-10-17
NO942641L (no) 1995-01-20
CA2128046A1 (en) 1995-01-20
US5378725A (en) 1995-01-03
AU678831B2 (en) 1997-06-12
CZ169294A3 (en) 1995-02-15
AU6754094A (en) 1995-01-27
HUT67667A (en) 1995-04-28
RU94026082A (ru) 1996-05-20
IL110325A0 (en) 1994-10-21

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