|
US5504103A
(en)
*
|
1993-08-25 |
1996-04-02 |
Eli Lilly And Company |
Inhibition of phosphatidylinositol 3-kinase with 17 β-hydroxywortmannin and analogs thereof
|
|
US5468773A
(en)
*
|
1993-08-25 |
1995-11-21 |
Eli Lilly And Company |
Methods for inhibiting bone loss and cartilage degradation using wortmannin and its analogs
|
|
US7863429B2
(en)
*
|
1995-12-21 |
2011-01-04 |
Qlt Inc. |
Treatment of inflammatory diseases including psoriasis
|
|
US5910417A
(en)
*
|
1996-05-31 |
1999-06-08 |
National Jewish Center For Immunology And Respiratory Medicine |
Regulation of cytokine production in a hematopoietic cell
|
|
US7670767B1
(en)
*
|
1997-01-16 |
2010-03-02 |
The Regents Of The University Of California |
Genetic alterations associated with cancer
|
|
EP1745797A3
(en)
*
|
1998-03-24 |
2007-07-18 |
Chugai Seiyaku Kabushiki Kaisha |
Vascularization inhibitors
|
|
US6413773B1
(en)
*
|
1998-06-01 |
2002-07-02 |
The Regents Of The University Of California |
Phosphatidylinositol 3-kinase inhibitors as stimulators of endocrine differentiation
|
|
BR9914465A
(pt)
*
|
1998-09-29 |
2001-10-09 |
Gamida Cell Ltd |
Métodos para controlar a proliferação e a diferenciação de células-tronco e células progenitoras e uma composição farmacêutica para induzir a diferenciação em uma população de células
|
|
ATE538794T1
(de)
*
|
1999-01-13 |
2012-01-15 |
Bayer Healthcare Llc |
Gamma carboxyarylsubstituierte diphenylharnstoffverbindungen als p38 kinasehemmer
|
|
US8124630B2
(en)
|
1999-01-13 |
2012-02-28 |
Bayer Healthcare Llc |
ω-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors
|
|
US6566081B1
(en)
|
1999-10-06 |
2003-05-20 |
The Brigham And Women's Hospital, Inc. |
Methods of identifying a compound which modulates the non-transcriptional non-map-kinase induced effects of steroid hormones
|
|
US6667300B2
(en)
*
|
2000-04-25 |
2003-12-23 |
Icos Corporation |
Inhibitors of human phosphatidylinositol 3-kinase delta
|
|
US6777439B2
(en)
*
|
2000-05-30 |
2004-08-17 |
Advanced Research & Technology Institute, Inc. |
Compositions and methods for identifying agents which modulate PTEN function and PI-3 kinase pathways
|
|
AU2002258798A1
(en)
*
|
2001-04-13 |
2002-10-28 |
Children's Hospital Medical Center |
Methods for the treatment of hepatic disorders
|
|
US7371763B2
(en)
*
|
2001-04-20 |
2008-05-13 |
Bayer Pharmaceuticals Corporation |
Inhibition of raf kinase using quinolyl, isoquinolyl or pyridyl ureas
|
|
GB0119865D0
(en)
|
2001-08-14 |
2001-10-10 |
Cancer Res Campaign Tech |
DNA-PK inhibitors
|
|
GB0119863D0
(en)
|
2001-08-14 |
2001-10-10 |
Cancer Res Campaign Tech |
DNA-PK inhibitors
|
|
US6703414B2
(en)
*
|
2001-09-14 |
2004-03-09 |
Arizona Board Of Regents On Behalf Of The University Of Arizona |
Device and method for treating restenosis
|
|
US20080108672A1
(en)
*
|
2002-01-11 |
2008-05-08 |
Bernd Riedl |
Omega-Carboxyaryl Substituted Diphenyl Ureas As Raf Kinase Inhibitors
|
|
IL152904A0
(en)
*
|
2002-01-24 |
2003-06-24 |
Gamida Cell Ltd |
Utilization of retinoid and vitamin d receptor antagonists for expansion of renewable stem cell populations
|
|
WO2003062404A1
(en)
*
|
2002-01-25 |
2003-07-31 |
Gamida-Cell Ltd. |
Methods of expanding stem and progenitor cells and expanded cell populations obtained thereby
|
|
US7838541B2
(en)
|
2002-02-11 |
2010-11-23 |
Bayer Healthcare, Llc |
Aryl ureas with angiogenesis inhibiting activity
|
|
US7049313B2
(en)
|
2002-02-25 |
2006-05-23 |
Kudos Pharmaceuticals Ltd. |
ATM inhibitors
|
|
AU2003248927A1
(en)
*
|
2002-07-10 |
2004-01-23 |
Massachusetts Institute Of Technology |
Solid-phase and solution-phase synthesis of glycosylphosphatidylinositol glycans
|
|
US20050054097A1
(en)
*
|
2002-11-17 |
2005-03-10 |
Tony Peled |
EX-VIVO expansion of hematopoietic system cell populations in mononuclear cell cultures
|
|
GB0304632D0
(en)
*
|
2003-02-28 |
2003-04-02 |
Proxara Biotechnology Ltd |
Method
|
|
UY28213A1
(es)
|
2003-02-28 |
2004-09-30 |
Bayer Pharmaceuticals Corp |
Nuevos derivados de cianopiridina útiles en el tratamiento de cáncer y otros trastornos.
|
|
US20050054103A1
(en)
*
|
2003-03-07 |
2005-03-10 |
Tony Peled |
Expansion of renewable stem cell populations using modulators of PI 3-kinase
|
|
WO2004093918A2
(en)
*
|
2003-04-23 |
2004-11-04 |
Wyeth Holdings Corporation |
Peg-wortmannin conjugates
|
|
WO2004113274A2
(en)
*
|
2003-05-20 |
2004-12-29 |
Bayer Pharmaceuticals Corporation |
Diaryl ureas with kinase inhibiting activity
|
|
IL161903A0
(en)
*
|
2003-07-17 |
2005-11-20 |
Gamida Cell Ltd |
Ex vivo progenitor and stem cell expansion for usein the treatment of disease of endodermally- deri ved organs
|
|
RS52625B
(sr)
*
|
2003-07-23 |
2013-06-28 |
Bayer Healthcare Llc |
Fluoro supstituisana omega-karboksiaril difenil urea za lečenje i prevenciju bolesti i stanja bolesti
|
|
DE602004026071D1
(de)
|
2003-08-13 |
2010-04-29 |
Kudos Pharm Ltd |
Aminopyrone und ihre verwendung als atm inhibitoren
|
|
WO2005016348A1
(en)
*
|
2003-08-14 |
2005-02-24 |
Icos Corporation |
Method of inhibiting immune responses stimulated by an endogenous factor
|
|
WO2005016349A1
(en)
*
|
2003-08-14 |
2005-02-24 |
Icos Corporation |
Methods of inhibiting leukocyte accumulation
|
|
PL1761540T3
(pl)
|
2004-05-13 |
2017-06-30 |
Icos Corporation |
Chinazolinony jako inhibitory ludzkiej kinazy 3-fosfatydyloinozytolu delta
|
|
JP2008500338A
(ja)
*
|
2004-05-25 |
2008-01-10 |
イコス・コーポレイション |
造血細胞の異常増殖を治療及び/又は予防する方法
|
|
EP1799812A4
(en)
*
|
2004-09-16 |
2009-09-09 |
Gamida Cell Ltd |
EX VIVO CULTIVATION METHODS OF STEM CELLS AND PRECURSOR BY CO-CULTURE WITH MESENCHYMAL CELLS
|
|
RU2408596C2
(ru)
|
2004-09-20 |
2011-01-10 |
Кудос Фармасьютикалс Лимитед |
Ингибиторы днк-пк
|
|
TW200626610A
(en)
*
|
2004-10-13 |
2006-08-01 |
Wyeth Corp |
Analogs of 17-hydroxywortmannin as PI3K inhibitors
|
|
CN1875959B
(zh)
*
|
2004-10-14 |
2010-05-12 |
孔庆忠 |
一种抗癌药物组合物
|
|
CN100369632C
(zh)
*
|
2004-10-14 |
2008-02-20 |
孔庆忠 |
抗癌药物组合物
|
|
WO2006085067A1
(en)
|
2005-02-09 |
2006-08-17 |
Kudos Pharmaceuticals Limited |
Atm inhibitors
|
|
EP1885356A2
(en)
*
|
2005-02-17 |
2008-02-13 |
Icos Corporation |
Phosphoinositide 3-kinase inhibitors for inhibiting leukocyte accumulation
|
|
AR053358A1
(es)
|
2005-04-15 |
2007-05-02 |
Cancer Rec Tech Ltd |
Inhibidores de adn - pk
|
|
JP2008543277A
(ja)
*
|
2005-05-11 |
2008-12-04 |
ジェネティック テクノロジーズ リミテッド |
胎児細胞を富化する方法
|
|
WO2006125539A2
(en)
*
|
2005-05-27 |
2006-11-30 |
Bayer Healthcare Ag |
Combination therapy comprising diaryl ureas for treating diseases
|
|
JP2007063205A
(ja)
*
|
2005-08-31 |
2007-03-15 |
Japan Science & Technology Agency |
神経因性疼痛治療剤
|
|
US8846393B2
(en)
|
2005-11-29 |
2014-09-30 |
Gamida-Cell Ltd. |
Methods of improving stem cell homing and engraftment
|
|
WO2008056368A2
(en)
*
|
2006-11-09 |
2008-05-15 |
Gamida-Cell Ltd. |
Use of ex-vivo cultured hematopoietic cells for treatment of peripheral vascular diseases
|
|
TW200845960A
(en)
*
|
2007-04-05 |
2008-12-01 |
Wyeth Corp |
Wortmannin-rapalog conjugate and uses thereof
|
|
US20100109416A1
(en)
*
|
2008-11-03 |
2010-05-06 |
Jones Margaret L |
Adjustable safety harness
|
|
NZ631024A
(en)
|
2008-11-13 |
2016-04-29 |
Gilead Calistoga Llc |
Therapies for hematologic malignancies
|
|
US9492449B2
(en)
|
2008-11-13 |
2016-11-15 |
Gilead Calistoga Llc |
Therapies for hematologic malignancies
|
|
US20100233733A1
(en)
*
|
2009-02-10 |
2010-09-16 |
Nodality, Inc., A Delaware Corporation |
Multiple mechanisms for modulation of the pi3 kinase pathway
|
|
SG174529A1
(en)
|
2009-03-24 |
2011-10-28 |
Gilead Calistoga Llc |
Atropisomers of2-purinyl-3-tolyl-quinazolinone derivatives and methods of use
|
|
PT2421536E
(pt)
*
|
2009-04-20 |
2015-10-20 |
Gilead Calistoga Llc |
Métodos de tratamento para tumores sólidos
|
|
EP2456443A1
(en)
|
2009-07-21 |
2012-05-30 |
Gilead Calistoga LLC |
Treatment of liver disorders with pi3k inhibitors
|
|
BRPI1107182B1
(pt)
*
|
2011-12-29 |
2022-03-08 |
Fundação De Amparo À Pesquisa Do Estado De Minas Gerais - Fapemig |
Composições farmacêuticas contendo ang-(1-7) ou outro agonista do receptor mas em combinação com inibidores de pi3k/akt para tratamento terapêutico anticâncer
|
|
BR112014020119A2
(pt)
|
2012-02-13 |
2020-10-27 |
Gamida-Cell Ltd |
cultura de células-tronco mesenquimais
|
|
AP2014007875A0
(en)
|
2012-03-05 |
2014-08-31 |
Gilead Calistoga Llc |
Polymorphic forms of (S)-2-(1-(9H-purin-6-ylamino)propyl)-5-fluoro-3-phenylquinazolin-4(3H)-one
|
|
US9567569B2
(en)
|
2012-07-23 |
2017-02-14 |
Gamida Cell Ltd. |
Methods of culturing and expanding mesenchymal stem cells
|
|
US9175266B2
(en)
|
2012-07-23 |
2015-11-03 |
Gamida Cell Ltd. |
Enhancement of natural killer (NK) cell proliferation and activity
|
|
WO2014203129A1
(en)
|
2013-06-19 |
2014-12-24 |
Olema Pharmaceuticals, Inc. |
Combinations of benzopyran compounds, compositions and uses thereof
|
|
EP3083623A1
(en)
|
2013-12-20 |
2016-10-26 |
Gilead Calistoga LLC |
Polymorphic forms of a hydrochloride salt of (s) -2-(9h-purin-6-ylamino) propyl) -5-fluoro-3-phenylquinazolin-4 (3h) -one
|
|
PT3083630T
(pt)
|
2013-12-20 |
2019-11-15 |
Gilead Calistoga Llc |
Procedimentos para inibidores da fosfatidilinositol 3-quinase
|
|
JP6455995B2
(ja)
|
2014-06-13 |
2019-01-23 |
ギリアード サイエンシーズ, インコーポレイテッド |
ホスファチジルイノシトール3−キナーゼ阻害剤
|
|
CN104774239B
(zh)
*
|
2015-03-13 |
2017-01-04 |
暨南大学 |
多节孢绿胶霉素类化合物及其用途
|
|
CN107058137B
(zh)
*
|
2017-06-14 |
2020-02-07 |
海正药业(杭州)有限公司 |
一种渥曼青霉及其生产渥曼青霉素的方法
|