ZA943862B - Method of preventing emesis and treating sexual dysfunction using tetrahydrobenz[cd] indole-6-carboxamides - Google Patents

Method of preventing emesis and treating sexual dysfunction using tetrahydrobenz[cd] indole-6-carboxamides

Info

Publication number
ZA943862B
ZA943862B ZA943862A ZA943862A ZA943862B ZA 943862 B ZA943862 B ZA 943862B ZA 943862 A ZA943862 A ZA 943862A ZA 943862 A ZA943862 A ZA 943862A ZA 943862 B ZA943862 B ZA 943862B
Authority
ZA
South Africa
Prior art keywords
tetrahydrobenz
carboxamides
indole
sexual dysfunction
treating sexual
Prior art date
Application number
ZA943862A
Other languages
English (en)
Inventor
Mark Mortensen Foreman
J David Leander
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of ZA943862B publication Critical patent/ZA943862B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Urology & Nephrology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA943862A 1993-06-10 1994-06-02 Method of preventing emesis and treating sexual dysfunction using tetrahydrobenz[cd] indole-6-carboxamides ZA943862B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US7519893A 1993-06-10 1993-06-10

Publications (1)

Publication Number Publication Date
ZA943862B true ZA943862B (en) 1995-12-04

Family

ID=22124191

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA943862A ZA943862B (en) 1993-06-10 1994-06-02 Method of preventing emesis and treating sexual dysfunction using tetrahydrobenz[cd] indole-6-carboxamides

Country Status (17)

Country Link
US (1) US5703112A (cs)
EP (2) EP0633023A3 (cs)
JP (1) JPH0748254A (cs)
KR (2) KR100367792B1 (cs)
CN (2) CN1072932C (cs)
AU (1) AU677317B2 (cs)
CA (1) CA2125088A1 (cs)
CZ (2) CZ285829B6 (cs)
HK (1) HK1043322B (cs)
HU (1) HUT71464A (cs)
IL (1) IL109872A (cs)
NO (4) NO321500B1 (cs)
NZ (2) NZ314570A (cs)
RU (1) RU2154476C2 (cs)
TW (1) TW258660B (cs)
UA (2) UA29415C2 (cs)
ZA (1) ZA943862B (cs)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000066114A1 (en) 1999-04-30 2000-11-09 Lilly Icos Llc Treatment of female arousal disorder
GB0106446D0 (en) * 2001-03-15 2001-05-02 Vernalis Res Ltd Chemical compounds
PL1890684T3 (pl) 2005-06-08 2014-05-30 Sk Biopharmaceuticals Co Ltd Leczenie zaburzeń snu i czuwania
EP1893291B1 (en) * 2005-06-22 2010-03-03 SK Holdings Co., Ltd. Treatment of sexual dysfunction
US8741950B2 (en) 2009-06-22 2014-06-03 Sk Biopharmaceuticals Co., Ltd. Methods for treating or preventing fatigue
CN102781436B (zh) 2009-11-06 2014-01-08 爱思开生物制药株式会社 纤维肌痛综合征的治疗方法
RU2556585C2 (ru) 2009-11-06 2015-07-10 Ск Биофармасъютиклс Ко., Лтд. Способы лечения синдрома дефицита внимания и гиперактивности
US9610274B2 (en) 2010-06-30 2017-04-04 Sk Biopharmaceuticals Co., Ltd. Methods for treating bipolar disorder
TWI684450B (zh) 2013-03-13 2020-02-11 南韓商愛思開生物製藥股份有限公司 猝倒症之治療
EP3021838B1 (en) 2013-07-18 2020-05-27 Jazz Pharmaceuticals Ireland Limited Treatment for obesity
US10195151B2 (en) 2016-09-06 2019-02-05 Jazz Pharmaceuticals International Iii Limited Formulations of (R)-2-amino-3-phenylpropyl carbamate
WO2018222954A1 (en) 2017-06-02 2018-12-06 Jazz Pharmaceuticals International Iii Limited Methods and compositions for treating excessive sleepiness
US10940133B1 (en) 2020-03-19 2021-03-09 Jazz Pharmaceuticals Ireland Limited Methods of providing solriamfetol therapy to subjects with impaired renal function

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4110339A (en) * 1977-11-25 1978-08-29 Eli Lilly And Company 4-(Di-n-propyl)amino-1,3,4,5-tetrahydrobenz[cd]indole
US4521421A (en) * 1983-09-26 1985-06-04 Eli Lilly And Company Treatment of sexual dysfunction
US4576959A (en) * 1984-02-06 1986-03-18 Eli Lilly And Company 6-Substituted-4-dialkylaminotetrahydrobenz[c,d]indoles
CA1266482A1 (en) * 1984-05-24 1990-03-06 Carl Kaiser 6-oxygenated-1,3,4,5-tetrahydrobenz(cd)indol-4-amines
US4745126A (en) * 1987-03-12 1988-05-17 Eli Lilly And Company Method of treating anxiety with tetrahydrobenz[c,d]indole-6-carboxamides
US4943428A (en) * 1987-07-10 1990-07-24 Wright State University Stimulation of serotonin-1A receptors in mammals to alleviate motion sickness and emesis induced by chemical agents
DE3809155A1 (de) * 1988-03-18 1989-09-28 Bayer Ag 1,3,4,5-tetrahydrobenz-(c,d)-indole
US5204340A (en) * 1989-04-11 1993-04-20 Eli Lilly And Company Tetrahydrobenz(c,d)indole serotonin agonists
CA2057912C (en) * 1989-07-13 1996-10-29 Chiu-Hong Lin (1,2n) and (3,2n)-carbocyclic-2-amino tetralin derivatives
US5302612A (en) * 1990-02-26 1994-04-12 Eli Lilly And Company 6-substituted-hexahydrobenz[cd]indoles
IL97308A (en) * 1990-02-26 1996-10-31 Lilly Co Eli Xahydrobenz [DC] Induced indoles in position 6, their preparation process and pharmaceutical preparations containing them
WO1991013872A1 (en) * 1990-03-15 1991-09-19 The Upjohn Company Therapeutically useful heterocyclic indole compounds
US5096908A (en) * 1990-05-04 1992-03-17 Eli Lilly And Company Method of inhibiting gastric acid secretion
US5258379A (en) * 1990-05-04 1993-11-02 Eli Lilly And Company Method of inhibiting gastric acid secretion with n-arylpiperazines
US5229409A (en) * 1990-08-15 1993-07-20 Eli Lilly And Company 6-substituted-tetrahydrobenz[cd]indoles
US5244912A (en) * 1991-03-28 1993-09-14 Eli Lilly And Company 6-heterocyclic-4-amino-1,3,4,5-tetrahydrobenz(cd)indoles and pharmaceutical use thereof

Also Published As

Publication number Publication date
CN1072932C (zh) 2001-10-17
UA29415C2 (uk) 2000-11-15
CN1342457A (zh) 2002-04-03
TW258660B (cs) 1995-10-01
HU9401730D0 (en) 1994-09-28
NO991551D0 (no) 1999-03-30
NZ260667A (en) 1997-05-26
CZ285762B6 (cs) 1999-11-17
RU2154476C2 (ru) 2000-08-20
HK1043322B (zh) 2005-06-03
AU6460794A (en) 1994-12-15
CN1170536C (zh) 2004-10-13
CZ285829B6 (cs) 1999-11-17
NO321500B1 (no) 2006-05-15
KR950000146A (ko) 1995-01-03
KR100367792B1 (ko) 2003-02-19
AU677317B2 (en) 1997-04-17
NO308693B1 (no) 2000-10-16
KR100367791B1 (ko) 2003-02-14
UA37311C2 (uk) 2001-05-15
IL109872A0 (en) 1994-10-07
EP1166783A3 (en) 2002-01-09
CN1100634A (zh) 1995-03-29
CA2125088A1 (en) 1994-12-11
EP1166783A2 (en) 2002-01-02
RU94020717A (ru) 1996-08-27
EP0633023A2 (en) 1995-01-11
US5703112A (en) 1997-12-30
NO993461D0 (no) 1999-07-14
EP0633023A3 (en) 1995-03-29
NO993461L (no) 1994-12-12
JPH0748254A (ja) 1995-02-21
NO991551L (no) 1994-12-12
IL109872A (en) 2000-12-06
NO20015806L (no) 1994-12-12
NO942143L (no) 1994-12-12
NZ314570A (en) 2000-11-24
CZ135494A3 (en) 1994-12-15
HUT71464A (en) 1995-11-28
HK1043322A1 (en) 2002-09-13
NO942143D0 (no) 1994-06-09
NO20015806D0 (no) 2001-11-28

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