ZA942251B - Protein formulation. - Google Patents

Protein formulation.

Info

Publication number
ZA942251B
ZA942251B ZA942251A ZA942251A ZA942251B ZA 942251 B ZA942251 B ZA 942251B ZA 942251 A ZA942251 A ZA 942251A ZA 942251 A ZA942251 A ZA 942251A ZA 942251 B ZA942251 B ZA 942251B
Authority
ZA
South Africa
Prior art keywords
factor viii
pct
aqueous solution
present
activity
Prior art date
Application number
ZA942251A
Other languages
English (en)
Inventor
Thomas Oesterberg
Angelica Fatouros
Original Assignee
Kabi Pharmacia Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kabi Pharmacia Ab filed Critical Kabi Pharmacia Ab
Publication of ZA942251B publication Critical patent/ZA942251B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A61K38/37—Factors VIII
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/16—Blood plasma; Blood serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Virology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
ZA942251A 1993-05-07 1994-04-02 Protein formulation. ZA942251B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE19939301581A SE9301581D0 (sv) 1993-05-07 1993-05-07 Protein formulation

Publications (1)

Publication Number Publication Date
ZA942251B true ZA942251B (en) 1994-11-01

Family

ID=20389868

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA942251A ZA942251B (en) 1993-05-07 1994-04-02 Protein formulation.

Country Status (24)

Country Link
US (1) US5962650A (et)
EP (1) EP0700299B1 (et)
JP (1) JP3751633B2 (et)
KR (1) KR100304143B1 (et)
CN (1) CN1113655C (et)
AT (1) ATE218354T1 (et)
AU (1) AU681883B2 (et)
CA (1) CA2161350C (et)
CZ (1) CZ293527B6 (et)
DE (1) DE69430745T2 (et)
DK (1) DK0700299T3 (et)
EE (1) EE03118B1 (et)
ES (1) ES2177579T3 (et)
FI (1) FI111910B (et)
HU (1) HU215263B (et)
NO (1) NO321769B1 (et)
NZ (1) NZ266031A (et)
PL (1) PL174866B1 (et)
PT (1) PT700299E (et)
RU (1) RU2142290C1 (et)
SE (1) SE9301581D0 (et)
SK (1) SK283002B6 (et)
WO (1) WO1994026286A1 (et)
ZA (1) ZA942251B (et)

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US5763401A (en) * 1996-07-12 1998-06-09 Bayer Corporation Stabilized albumin-free recombinant factor VIII preparation having a low sugar content
DE60035260T2 (de) * 1999-02-22 2007-10-18 The University Of Connecticut, Farmington Neue albuminfreie faktor viii formulierungen
NZ516400A (en) * 1999-07-13 2004-02-27 Biovitrum Ab Stable factor VIII compositions
JP3466516B2 (ja) 1999-09-07 2003-11-10 科学技術振興事業団 安定保存可能な酸素輸液剤
AU2002351755A1 (en) * 2001-12-21 2003-07-15 Novo Nordisk A/S Liquid composition of modified factor vii polypeptides
EP1458408B1 (en) 2001-12-21 2009-04-15 Novo Nordisk Health Care AG Liquid composition of factor vii polypeptides
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US20040009918A1 (en) * 2002-05-03 2004-01-15 Hanne Nedergaard Stabilised solid compositions of modified factor VII
EP1517698B2 (en) * 2002-06-21 2017-12-06 Novo Nordisk Health Care AG STABILISED SOLID COMPOSITIONS OF FACTOR VIIa POLYPEPTIDES
US7897734B2 (en) * 2003-03-26 2011-03-01 Novo Nordisk Healthcare Ag Method for the production of proteins
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ATE446768T1 (de) * 2003-07-01 2009-11-15 Novo Nordisk Healthcare Ag Flüssige wässrige pharmazeutische zusammnesetzung von factor vii polypeptiden
EP1656158B1 (en) 2003-08-14 2016-03-09 Novo Nordisk Health Care AG Liquid, aqueous pharmaceutical composition of factor vii polypeptides
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US7504377B2 (en) 2006-10-23 2009-03-17 Ikor, Inc. Nitric oxide-blocked cross-linked tetrameric hemoglobin
US7494974B2 (en) 2006-10-24 2009-02-24 Ikor, Inc. Carboxymethylated cross-linked tetrameric hemoglobin
ATE471158T1 (de) * 2007-04-17 2010-07-15 Schwabe Willmar Gmbh & Co Verfahren zur herstellung von lagerstabilen lösungen aus pelargonium-extrakten
JP5323072B2 (ja) * 2007-07-11 2013-10-23 ノボ・ノルデイスク・エー／エス 混合方式又は多様式樹脂を使用する第ｖｉｉｉ因子の精製
EP2113564A1 (en) 2008-05-01 2009-11-04 Arecor Limited Protein formulation
JP2012500250A (ja) 2008-08-21 2012-01-05 オクタファルマ アクチェン ゲゼルシャフト 組換えにより産生したヒト第ｖｉｉｉ及び第ｉｘ因子
CA2735376C (en) * 2008-09-03 2016-11-29 Octapharma Ag New protecting compositions for recombinantly produced factor viii
NZ593190A (en) 2008-11-07 2013-01-25 Baxter Int Factor viii formulations
US10172950B2 (en) 2009-06-09 2019-01-08 Prolong Pharmaceuticals, LLC Hemoglobin compositions
NO2440239T3 (et) 2009-06-09 2018-02-10
US10172949B2 (en) 2009-06-09 2019-01-08 Prolong Pharmaceuticals, LLC Hemoglobin compositions
GB0915480D0 (en) * 2009-09-04 2009-10-07 Arecor Ltd Stable formulation of factor viii
US11284616B2 (en) 2010-05-05 2022-03-29 Hemanext Inc. Irradiation of red blood cells and anaerobic storage
US9199016B2 (en) 2009-10-12 2015-12-01 New Health Sciences, Inc. System for extended storage of red blood cells and methods of use
EP4091645A1 (en) 2010-08-25 2022-11-23 Hemanext Inc. Method for enhancing red blood cell quality and survival during storage
KR101948337B1 (ko) 2010-11-05 2019-02-14 박스알타 인코퍼레이티드 증가된 특이 활성도를 갖는 항혈우병 인자 ｖｉｉｉ의 신규 변이체
ES2957338T3 (es) 2010-11-05 2024-01-17 Hemanext Inc Irradiación de glóbulos rojos y almacenamiento anaeróbico
US9067004B2 (en) 2011-03-28 2015-06-30 New Health Sciences, Inc. Method and system for removing oxygen and carbon dioxide during red cell blood processing using an inert carrier gas and manifold assembly
ES2923571T3 (es) 2011-08-10 2022-09-28 Hemanext Inc Dispositivo integrado de filtrado de leucocitos, oxígeno y/o CO2 y separación de plasma
EP3967143A1 (en) 2013-02-28 2022-03-16 Hemanext Inc. Gas addition device for blood treatment and corresponding method
ES2524516B1 (es) * 2014-05-29 2015-03-31 Grifols Worldwide Operations Limited Procedimiento de preparación de albúmina humana con nivel de oxígeno disuelto reducido
IL299978B1 (en) 2015-03-10 2024-04-01 Hemanext Inc Single-use oxygen reduction kits, devices and methods for their use
KR20240067253A (ko) 2015-04-23 2024-05-16 헤마넥스트 인코포레이티드 혐기성 혈액 저장 용기
MX2017014812A (es) 2015-05-18 2018-05-11 New Health Sciences Inc Metodos para el almacenamiento de sangre completa y composiciones de esta.
CN109195632A (zh) 2016-05-27 2019-01-11 新健康科学股份有限公司 厌氧血液储存和病原体失活方法
WO2020030572A1 (en) 2018-08-07 2020-02-13 Glaxosmithkline Biologicals Sa Processes and vaccines

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DE3144705C2 (de) * 1981-11-11 1983-12-08 Biotest-Serum-Institut Gmbh, 6000 Frankfurt Verfahren zur Herstellung eines lagerstabilen, vernetzten Hämoglobinpräparates mit hoher Sauerstoff-Transportkapazität, sowie das nach diesem Verfahren hergestellte Hämoglobinpräparat
US4481189A (en) * 1982-04-14 1984-11-06 New York Blood Center Inc. Process for preparing sterilized plasma and plasma derivatives
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ATE52922T1 (de) * 1985-08-05 1990-06-15 Immuno Ag Verfahren zur herstellung von praeparationen auf basis von blutgerinnungsfaktoren.
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Also Published As

Publication number Publication date
RU2142290C1 (ru) 1999-12-10
HU9503171D0 (en) 1996-01-29
ES2177579T3 (es) 2002-12-16
SK138395A3 (en) 1997-02-05
DE69430745D1 (de) 2002-07-11
AU6659794A (en) 1994-12-12
FI955305A0 (fi) 1995-11-06
JP3751633B2 (ja) 2006-03-01
EP0700299A1 (en) 1996-03-13
NO321769B1 (no) 2006-07-03
PT700299E (pt) 2002-11-29
JPH08509745A (ja) 1996-10-15
SE9301581D0 (sv) 1993-05-07
FI955305A (fi) 1995-11-06
CN1122573A (zh) 1996-05-15
ATE218354T1 (de) 2002-06-15
HU215263B (hu) 1998-11-30
FI111910B (fi) 2003-10-15
KR960702317A (ko) 1996-04-27
CA2161350C (en) 2007-10-30
HUT73693A (en) 1996-09-30
CA2161350A1 (en) 1994-11-24
KR100304143B1 (ko) 2001-11-22
EE03118B1 (et) 1998-10-15
NO954457D0 (no) 1995-11-07
CN1113655C (zh) 2003-07-09
SK283002B6 (sk) 2003-01-09
DK0700299T3 (da) 2002-09-23
WO1994026286A1 (en) 1994-11-24
NO954457L (no) 1995-11-07
EP0700299B1 (en) 2002-06-05
DE69430745T2 (de) 2002-10-17
AU681883B2 (en) 1997-09-11
CZ286995A3 (en) 1996-05-15
PL311567A1 (en) 1996-02-19
US5962650A (en) 1999-10-05
CZ293527B6 (cs) 2004-05-12
NZ266031A (en) 1997-04-24
PL174866B1 (pl) 1998-09-30

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