ZA9410339B - Diazabicyclic neurokinin antagonists - Google Patents
Diazabicyclic neurokinin antagonistsInfo
- Publication number
- ZA9410339B ZA9410339B ZA9410339A ZA9410339A ZA9410339B ZA 9410339 B ZA9410339 B ZA 9410339B ZA 9410339 A ZA9410339 A ZA 9410339A ZA 9410339 A ZA9410339 A ZA 9410339A ZA 9410339 B ZA9410339 B ZA 9410339B
- Authority
- ZA
- South Africa
- Prior art keywords
- diazabicyclic
- neurokinin antagonists
- compounds
- formula
- disorders
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Immunology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Anesthesiology (AREA)
- Pulmonology (AREA)
- Rheumatology (AREA)
- Hospice & Palliative Care (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17503493A | 1993-12-29 | 1993-12-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA9410339B true ZA9410339B (en) | 1996-06-28 |
Family
ID=22638565
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA9410339A ZA9410339B (en) | 1993-12-29 | 1994-12-28 | Diazabicyclic neurokinin antagonists |
Country Status (26)
| Country | Link |
|---|---|
| US (2) | US5854239A (xx) |
| EP (1) | EP0737194B1 (xx) |
| JP (1) | JP2895630B2 (xx) |
| KR (1) | KR100197454B1 (xx) |
| CN (1) | CN1046515C (xx) |
| AT (1) | ATE177099T1 (xx) |
| AU (1) | AU699465B2 (xx) |
| BR (1) | BR9408450A (xx) |
| CA (1) | CA2180263C (xx) |
| CO (1) | CO4230019A1 (xx) |
| CZ (1) | CZ282567B6 (xx) |
| DE (1) | DE69416869T2 (xx) |
| DK (1) | DK0737194T3 (xx) |
| ES (1) | ES2127946T3 (xx) |
| FI (1) | FI108296B (xx) |
| GR (1) | GR3029853T3 (xx) |
| HU (1) | HUT74682A (xx) |
| IL (1) | IL112118A (xx) |
| NO (1) | NO305600B1 (xx) |
| NZ (1) | NZ274915A (xx) |
| PE (1) | PE49395A1 (xx) |
| PL (1) | PL179435B1 (xx) |
| RU (1) | RU2124014C1 (xx) |
| TW (1) | TW369526B (xx) |
| WO (1) | WO1995018129A1 (xx) |
| ZA (1) | ZA9410339B (xx) |
Families Citing this family (68)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2124014C1 (ru) * | 1993-12-29 | 1998-12-27 | Пфайзер Инк. | Диазабициклические соединения и содержащая их фармацевтическая композиция |
| FR2786770B1 (fr) * | 1998-12-04 | 2001-01-19 | Synthelabo | Derives de 1,4-diazabicyclo[3.2.2.]nonane, leur preparation et leur application en therapeutique |
| DE60129562T2 (de) * | 2000-06-12 | 2008-04-17 | The University Of Rochester | Methode zur Behandlung von Hitzewallungen durch Verwendung eines Tachykinin-Rezeptor-Antagonisten |
| FR2812635B1 (fr) * | 2000-08-01 | 2002-10-11 | Aventis Pharma Sa | Nouveaux composes heterocycliques, preparation et utilisation comme medicaments notamment comme anti- bacteriens |
| SE0003795D0 (sv) | 2000-10-20 | 2000-10-20 | Astrazeneca Ab | Pharmaceutically useful compounds |
| FR2825705B1 (fr) | 2001-06-08 | 2005-05-20 | Aventis Pharma Sa | Nouveaux composes heterocycliques, leur preparation et leur utilisation comme medicaments, notamment comme anti-bacteriens |
| FR2835186B1 (fr) * | 2002-01-28 | 2006-10-20 | Aventis Pharma Sa | Nouveaux composes heterocycliques, actifs comme inhibiteurs de beta-lactamases |
| FR2844273B1 (fr) | 2002-09-05 | 2008-04-04 | Aventis Pharma Sa | Nouveaux composes heterocycliques, procede et intermediaires de preparation et utilisation comme medicament, notamment comme inhibiteurs de beta-lactamases et anti-bacteriens. |
| US7439253B2 (en) | 2002-12-06 | 2008-10-21 | Novexel | Heterocyclic compounds, their preparation and their use as medicaments, in particular as antibacterials and beta-lactamase inhibitors |
| FR2848210B1 (fr) * | 2002-12-06 | 2007-10-19 | Aventis Pharma Sa | Nouveaux composes heterocycliques, leur preparation et leur utilisation comme medicaments, notamment comme anti-bacteriens et inhibiteurs de beta-lactamases |
| NZ552397A (en) | 2004-07-15 | 2011-04-29 | Amr Technology Inc | Aryl-and heteroaryl-substituted tetrahydroisoquinolines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin |
| ATE550019T1 (de) | 2005-05-17 | 2012-04-15 | Merck Sharp & Dohme | Cis-4-ä(4-chlorophenyl)sulfonylü-4-(2,5- difluorophenyl)cyclohexanepropansäure zur behandlug von krebs |
| US20060281670A1 (en) * | 2005-06-10 | 2006-12-14 | Wisconsin Alumni Research Foundation (Warf) | Compositions and methods for modulating angiogenesis |
| KR101589551B1 (ko) | 2005-07-15 | 2016-02-02 | 알바니 몰레큘라 리써치, 인크. | 아릴- 및 헤테로아릴-치환된 테트라히드로벤자제핀, 및 노르에피네프린, 도파민 및 세로토닌의 재흡수를 차단하기 위한 용도 |
| BRPI0616463A2 (pt) | 2005-09-29 | 2011-06-21 | Merck & Co Inc | composto, composição farmacêutica, e, uso de um composto |
| GB0603041D0 (en) | 2006-02-15 | 2006-03-29 | Angeletti P Ist Richerche Bio | Therapeutic compounds |
| CA2664113C (en) | 2006-09-22 | 2013-05-28 | Merck & Co., Inc. | Use of platencin and platensimycin as fatty acid synthesis inhibitors to treat obesity, diabetes and cancer |
| US20110218176A1 (en) | 2006-11-01 | 2011-09-08 | Barbara Brooke Jennings-Spring | Compounds, methods, and treatments for abnormal signaling pathways for prenatal and postnatal development |
| TWI405763B (zh) * | 2006-11-02 | 2013-08-21 | Targacept Inc | 菸鹼乙醯膽鹼受體亞型選擇性之二氮雜雙環烷類醯胺 |
| PL2109608T3 (pl) | 2007-01-10 | 2011-08-31 | Msd Italia Srl | Indazole podstawione grupą amidową jako inhibitory polimerazy poli(ADP-rybozy)-(PARP) |
| CA2682727C (en) | 2007-04-02 | 2016-03-22 | Banyu Pharmaceutical Co., Ltd. | Indoledione derivative |
| CA2690191C (en) | 2007-06-27 | 2015-07-28 | Merck Sharp & Dohme Corp. | 4-carboxybenzylamino derivatives as histone deacetylase inhibitors |
| ES2533826T3 (es) | 2008-01-18 | 2015-04-15 | Merck Sharp & Dohme Corp. | Inhibidores de beta-lactamasa |
| KR20100126467A (ko) | 2008-03-03 | 2010-12-01 | 타이거 파마테크 | 티로신 키나아제 억제제 |
| US9156812B2 (en) | 2008-06-04 | 2015-10-13 | Bristol-Myers Squibb Company | Crystalline form of 6-[(4S)-2-methyl-4-(2-naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine |
| WO2010114780A1 (en) | 2009-04-01 | 2010-10-07 | Merck Sharp & Dohme Corp. | Inhibitors of akt activity |
| KR20120034644A (ko) | 2009-05-12 | 2012-04-12 | 알바니 몰레큘라 리써치, 인크. | 아릴, 헤테로아릴, 및 헤테로사이클 치환된 테트라하이드로이소퀴놀린 및 이의 용도 |
| AU2010247735B2 (en) | 2009-05-12 | 2015-07-16 | Albany Molecular Research, Inc. | Crystalline forms of (S)-7-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-4-(3,4-dichlorophenyl)- 1,2,3,4-tetrahydroisoquinoline and use thereof |
| US8802696B2 (en) | 2009-05-12 | 2014-08-12 | Albany Molecular Research, Inc. | 7-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydroisoqu inoli and use thereof |
| FR2951171A1 (fr) * | 2009-10-09 | 2011-04-15 | Novexel | Nouveau sel de sodium d'un compose azabicyclique sous forme enantiomere cristallisee et nouvelles formes polymorphes et pseudopolymorphes ainsi que leur preparation |
| BR112012008849A2 (pt) | 2009-10-14 | 2015-09-22 | Schering Corp | composto, composição farmacêutica, e, uso de um composto |
| EP2584903B1 (en) | 2010-06-24 | 2018-10-24 | Merck Sharp & Dohme Corp. | Novel heterocyclic compounds as erk inhibitors |
| CN103068980B (zh) | 2010-08-02 | 2017-04-05 | 瑟纳治疗公司 | 使用短干扰核酸（siNA）的RNA干扰介导的联蛋白（钙粘蛋白关联蛋白质），β1（CTNNB1）基因表达的抑制 |
| SI2606134T1 (sl) | 2010-08-17 | 2019-08-30 | Sirna Therapeutics, Inc. | RNA-INTERFERENČNO POSREDOVANO ZAVIRANJE IZRAŽANJA GENA VIRUSA HEPATITISA B (HBV) Z UPORABO KRATKE INTERFERENČNE NUKLEINSKE KISLINE (siNA) |
| US8883801B2 (en) | 2010-08-23 | 2014-11-11 | Merck Sharp & Dohme Corp. | Substituted pyrazolo[1,5-a]pyrimidines as mTOR inhibitors |
| WO2012030685A2 (en) | 2010-09-01 | 2012-03-08 | Schering Corporation | Indazole derivatives useful as erk inhibitors |
| EP2615916B1 (en) | 2010-09-16 | 2017-01-04 | Merck Sharp & Dohme Corp. | Fused pyrazole derivatives as novel erk inhibitors |
| DK2632472T3 (en) | 2010-10-29 | 2018-03-19 | Sirna Therapeutics Inc | RNA INTERFERENCE-MEDIATED INHIBITION OF GENE EXPRESSION USING SHORT INTERFERRING NUCLEIC ACIDS (SINA) |
| WO2012087772A1 (en) | 2010-12-21 | 2012-06-28 | Schering Corporation | Indazole derivatives useful as erk inhibitors |
| CA2822758C (en) * | 2010-12-22 | 2018-03-20 | Meiji Seika Pharma Co., Ltd. | Optically active diazabicyclooctane derivative and process for preparing the same |
| IN2013MN02170A (xx) | 2011-04-21 | 2015-06-12 | Piramal Entpr Ltd | |
| AU2012303691B2 (en) * | 2011-08-27 | 2014-06-19 | Wockhardt Limited | 1,6- diazabicyclo [3,2,1] octan-7-one derivatives and their use in the treatment of bacterial infections |
| AU2012303693B2 (en) * | 2011-08-30 | 2014-07-03 | Wockhardt Limited | 1,6- diazabicyclo [3,2,1] octan- 7 - one derivatives and their use in the treatment of bacterial infections |
| BR112014003476A2 (pt) * | 2011-09-13 | 2017-03-01 | Wockhardt Ltd | compostos contendo nitrogênio e seu uso |
| EP2770987B1 (en) | 2011-10-27 | 2018-04-04 | Merck Sharp & Dohme Corp. | Novel compounds that are erk inhibitors |
| AR090539A1 (es) * | 2012-04-02 | 2014-11-19 | Astrazeneca Ab | COMPUESTOS INHIBIDORES DE b LACTAMASA |
| EP3919620A1 (en) | 2012-05-02 | 2021-12-08 | Sirna Therapeutics, Inc. | Short interfering nucleic acid (sina) compositions |
| PL2857401T3 (pl) * | 2012-05-30 | 2020-02-28 | Meiji Seika Pharma Co., Ltd. | NOWY INHIBITOR ß–LAKTAMAZY I SPOSÓB JEGO WYTWARZANIA |
| JP6280554B2 (ja) | 2012-09-28 | 2018-02-14 | メルク・シャープ・アンド・ドーム・コーポレーションＭｅｒｃｋ Ｓｈａｒｐ ＆ Ｄｏｈｍｅ Ｃｏｒｐ． | Ｅｒｋ阻害剤である新規化合物 |
| EP2919788A4 (en) | 2012-11-14 | 2016-05-25 | Univ Johns Hopkins | METHODS AND COMPOSITIONS FOR THE TREATMENT OF SCHIZOPHRENIA |
| PL2925888T3 (pl) | 2012-11-28 | 2018-03-30 | Merck Sharp & Dohme Corp. | Kompozycje i sposoby do stosowania w leczeniu nowotworów |
| WO2014100065A1 (en) | 2012-12-20 | 2014-06-26 | Merck Sharp & Dohme Corp. | Substituted imidazopyridines as hdm2 inhibitors |
| WO2014120748A1 (en) | 2013-01-30 | 2014-08-07 | Merck Sharp & Dohme Corp. | 2,6,7,8 substituted purines as hdm2 inhibitors |
| WO2014135932A1 (en) * | 2013-03-08 | 2014-09-12 | Wockhardt Limited | A process for preparation of (2s, 5r)-7-oxo-6-sulphooxy-2-[((3r)-pyrrolidine-3-carbonyl)-hydrazino carbonyl]-1,6-diaza-bicyclo[3.2.1]octane |
| US9862718B2 (en) * | 2013-03-08 | 2018-01-09 | Wockhardt Limited | Sodium salt of (2S, 5R)-6-benzyloxy-7-oxo-1,6-diaza-bicyclo [3.2.1] octane-2-carboxylic acid and its preparation |
| JP6182621B2 (ja) * | 2013-03-08 | 2017-08-16 | ウォックハート リミテッド | （２ｓ，５ｒ）−硫酸モノ−｛［（４−アミノピペリジン−４−イル）カルボニル］−７−オキソ−１，６−ジアザ−ビシクロ［３．２．１］オクタ−６−イル｝エステルを調製するための方法 |
| JP6285969B2 (ja) * | 2013-03-08 | 2018-02-28 | ウォックハート リミテッド | （２ｓ，５ｒ）−７−オキソ−６−スルホオキシ−２−［（（３ｒ）−ピペリジン−３−カルボニル）−ヒドラジノカルボニル］−１，６−ジアザ−ビシクロ［３．２．１］オクタンの調製のためのプロセス |
| US20160194368A1 (en) | 2013-09-03 | 2016-07-07 | Moderna Therapeutics, Inc. | Circular polynucleotides |
| JP6453222B2 (ja) * | 2013-09-24 | 2019-01-16 | Ｍｅｉｊｉ Ｓｅｉｋａファルマ株式会社 | ジアザビシクロオクタン誘導体の製造法とその中間体 |
| EA033829B1 (ru) | 2014-11-17 | 2019-11-29 | Entasis Therapeutics Ltd | Комбинированная терапия для лечения устойчивых бактериальных инфекций |
| WO2016156597A1 (en) | 2015-04-03 | 2016-10-06 | Mutabilis | Heterocyclic compounds and their use in preventing or treating bacterial infections |
| WO2018053215A1 (en) | 2016-09-16 | 2018-03-22 | Entasis Therapeutics Limited | Beta-lactamase inhibitor compounds |
| US10975084B2 (en) | 2016-10-12 | 2021-04-13 | Merck Sharp & Dohme Corp. | KDM5 inhibitors |
| HRP20220231T1 (hr) | 2017-05-08 | 2022-04-29 | Entasis Therapeutics, Inc. | Spojevi i postupci za liječenje bakterijskih infekcija |
| US10947234B2 (en) | 2017-11-08 | 2021-03-16 | Merck Sharp & Dohme Corp. | PRMT5 inhibitors |
| CN108610313B (zh) * | 2018-06-08 | 2022-03-04 | 三峡大学 | 一种酶抑制剂及其应用 |
| WO2020033284A1 (en) | 2018-08-07 | 2020-02-13 | Merck Sharp & Dohme Corp. | Prmt5 inhibitors |
| US11993602B2 (en) | 2018-08-07 | 2024-05-28 | Merck Sharp & Dohme Llc | PRMT5 inhibitors |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3494923A (en) * | 1965-05-28 | 1970-02-10 | Sterling Drug Inc | 1,2,3,4,5,8-hexahydro-1,5-methanobenzo (f)(1,4)diazocine |
| DE69200921T2 (de) * | 1991-03-01 | 1995-05-04 | Pfizer | 1-azabicyclo[3.2.2]nonan-3-aminderivate. |
| RU2124014C1 (ru) * | 1993-12-29 | 1998-12-27 | Пфайзер Инк. | Диазабициклические соединения и содержащая их фармацевтическая композиция |
-
1994
- 1994-11-14 RU RU96116128A patent/RU2124014C1/ru not_active IP Right Cessation
- 1994-11-14 KR KR1019960703516A patent/KR100197454B1/ko not_active IP Right Cessation
- 1994-11-14 WO PCT/IB1994/000352 patent/WO1995018129A1/en active IP Right Grant
- 1994-11-14 BR BR9408450A patent/BR9408450A/pt not_active Application Discontinuation
- 1994-11-14 JP JP7508341A patent/JP2895630B2/ja not_active Expired - Fee Related
- 1994-11-14 EP EP94931148A patent/EP0737194B1/en not_active Expired - Lifetime
- 1994-11-14 CN CN94194665A patent/CN1046515C/zh not_active Expired - Fee Related
- 1994-11-14 PL PL94315193A patent/PL179435B1/pl unknown
- 1994-11-14 ES ES94931148T patent/ES2127946T3/es not_active Expired - Lifetime
- 1994-11-14 AT AT94931148T patent/ATE177099T1/de not_active IP Right Cessation
- 1994-11-14 CZ CZ961886A patent/CZ282567B6/cs not_active IP Right Cessation
- 1994-11-14 DK DK94931148T patent/DK0737194T3/da active
- 1994-11-14 HU HU9601790A patent/HUT74682A/hu unknown
- 1994-11-14 NZ NZ274915A patent/NZ274915A/en unknown
- 1994-11-14 DE DE69416869T patent/DE69416869T2/de not_active Expired - Fee Related
- 1994-11-14 CA CA002180263A patent/CA2180263C/en not_active Expired - Fee Related
- 1994-11-14 US US08/669,283 patent/US5854239A/en not_active Expired - Fee Related
- 1994-11-14 AU AU80021/94A patent/AU699465B2/en not_active Ceased
- 1994-11-28 TW TW083111052A patent/TW369526B/zh active
- 1994-12-21 PE PE1994257627A patent/PE49395A1/es not_active Application Discontinuation
- 1994-12-22 IL IL11211894A patent/IL112118A/en not_active IP Right Cessation
- 1994-12-23 CO CO94058032A patent/CO4230019A1/es unknown
- 1994-12-28 ZA ZA9410339A patent/ZA9410339B/xx unknown
- 1994-12-28 FI FI946140A patent/FI108296B/fi not_active IP Right Cessation
-
1996
- 1996-06-28 NO NO962742A patent/NO305600B1/no unknown
-
1998
- 1998-11-23 US US09/198,171 patent/US6110919A/en not_active Expired - Fee Related
-
1999
- 1999-04-05 GR GR990400941T patent/GR3029853T3/el unknown
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