FI946140A0 - Diatsabisyklisiä neurokiniiniantagonisteja - Google Patents

Diatsabisyklisiä neurokiniiniantagonisteja

Info

Publication number
FI946140A0
FI946140A0 FI946140A FI946140A FI946140A0 FI 946140 A0 FI946140 A0 FI 946140A0 FI 946140 A FI946140 A FI 946140A FI 946140 A FI946140 A FI 946140A FI 946140 A0 FI946140 A0 FI 946140A0
Authority
FI
Finland
Prior art keywords
diazabicyclic
neurokinin antagonists
compounds
formula
disorders
Prior art date
Application number
FI946140A
Other languages
English (en)
Swedish (sv)
Other versions
FI108296B (fi
FI946140A (fi
Inventor
Jr Harry R Howard
Kevin D Shenk
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of FI946140A0 publication Critical patent/FI946140A0/fi
Publication of FI946140A publication Critical patent/FI946140A/fi
Application granted granted Critical
Publication of FI108296B publication Critical patent/FI108296B/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Immunology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI946140A 1993-12-29 1994-12-28 Menetelmä terapeuttisesti aktiivisten 1,6-diatsabisyklo[3.2.1]oktaani- ja 1,4-diatsabisyklo[3.3.1]nonaanijohdannaisten valmistamiseksi FI108296B (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17503493A 1993-12-29 1993-12-29
US17503493 1993-12-29

Publications (3)

Publication Number Publication Date
FI946140A0 true FI946140A0 (fi) 1994-12-28
FI946140A FI946140A (fi) 1995-06-30
FI108296B FI108296B (fi) 2001-12-31

Family

ID=22638565

Family Applications (1)

Application Number Title Priority Date Filing Date
FI946140A FI108296B (fi) 1993-12-29 1994-12-28 Menetelmä terapeuttisesti aktiivisten 1,6-diatsabisyklo[3.2.1]oktaani- ja 1,4-diatsabisyklo[3.3.1]nonaanijohdannaisten valmistamiseksi

Country Status (26)

Country Link
US (2) US5854239A (fi)
EP (1) EP0737194B1 (fi)
JP (1) JP2895630B2 (fi)
KR (1) KR100197454B1 (fi)
CN (1) CN1046515C (fi)
AT (1) ATE177099T1 (fi)
AU (1) AU699465B2 (fi)
BR (1) BR9408450A (fi)
CA (1) CA2180263C (fi)
CO (1) CO4230019A1 (fi)
CZ (1) CZ282567B6 (fi)
DE (1) DE69416869T2 (fi)
DK (1) DK0737194T3 (fi)
ES (1) ES2127946T3 (fi)
FI (1) FI108296B (fi)
GR (1) GR3029853T3 (fi)
HU (1) HUT74682A (fi)
IL (1) IL112118A (fi)
NO (1) NO305600B1 (fi)
NZ (1) NZ274915A (fi)
PE (1) PE49395A1 (fi)
PL (1) PL179435B1 (fi)
RU (1) RU2124014C1 (fi)
TW (1) TW369526B (fi)
WO (1) WO1995018129A1 (fi)
ZA (1) ZA9410339B (fi)

Families Citing this family (68)

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RU2124014C1 (ru) * 1993-12-29 1998-12-27 Пфайзер Инк. Диазабициклические соединения и содержащая их фармацевтическая композиция
FR2786770B1 (fr) * 1998-12-04 2001-01-19 Synthelabo Derives de 1,4-diazabicyclo[3.2.2.]nonane, leur preparation et leur application en therapeutique
DE60129562T2 (de) * 2000-06-12 2008-04-17 The University Of Rochester Methode zur Behandlung von Hitzewallungen durch Verwendung eines Tachykinin-Rezeptor-Antagonisten
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FR2825705B1 (fr) 2001-06-08 2005-05-20 Aventis Pharma Sa Nouveaux composes heterocycliques, leur preparation et leur utilisation comme medicaments, notamment comme anti-bacteriens
FR2835186B1 (fr) * 2002-01-28 2006-10-20 Aventis Pharma Sa Nouveaux composes heterocycliques, actifs comme inhibiteurs de beta-lactamases
FR2844273B1 (fr) 2002-09-05 2008-04-04 Aventis Pharma Sa Nouveaux composes heterocycliques, procede et intermediaires de preparation et utilisation comme medicament, notamment comme inhibiteurs de beta-lactamases et anti-bacteriens.
US7439253B2 (en) 2002-12-06 2008-10-21 Novexel Heterocyclic compounds, their preparation and their use as medicaments, in particular as antibacterials and beta-lactamase inhibitors
FR2848210B1 (fr) * 2002-12-06 2007-10-19 Aventis Pharma Sa Nouveaux composes heterocycliques, leur preparation et leur utilisation comme medicaments, notamment comme anti-bacteriens et inhibiteurs de beta-lactamases
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ATE550019T1 (de) 2005-05-17 2012-04-15 Merck Sharp & Dohme Cis-4-ä(4-chlorophenyl)sulfonylü-4-(2,5- difluorophenyl)cyclohexanepropansäure zur behandlug von krebs
US20060281670A1 (en) * 2005-06-10 2006-12-14 Wisconsin Alumni Research Foundation (Warf) Compositions and methods for modulating angiogenesis
KR101589551B1 (ko) 2005-07-15 2016-02-02 알바니 몰레큘라 리써치, 인크. 아릴- 및 헤테로아릴-치환된 테트라히드로벤자제핀, 및 노르에피네프린, 도파민 및 세로토닌의 재흡수를 차단하기 위한 용도
BRPI0616463A2 (pt) 2005-09-29 2011-06-21 Merck & Co Inc composto, composição farmacêutica, e, uso de um composto
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US20110218176A1 (en) 2006-11-01 2011-09-08 Barbara Brooke Jennings-Spring Compounds, methods, and treatments for abnormal signaling pathways for prenatal and postnatal development
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Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3494923A (en) * 1965-05-28 1970-02-10 Sterling Drug Inc 1,2,3,4,5,8-hexahydro-1,5-methanobenzo (f)(1,4)diazocine
DE69200921T2 (de) * 1991-03-01 1995-05-04 Pfizer 1-azabicyclo[3.2.2]nonan-3-aminderivate.
RU2124014C1 (ru) * 1993-12-29 1998-12-27 Пфайзер Инк. Диазабициклические соединения и содержащая их фармацевтическая композиция

Also Published As

Publication number Publication date
PL315193A1 (en) 1996-10-14
ES2127946T3 (es) 1999-05-01
ATE177099T1 (de) 1999-03-15
ZA9410339B (en) 1996-06-28
FI108296B (fi) 2001-12-31
GR3029853T3 (en) 1999-07-30
DE69416869D1 (de) 1999-04-08
NO962742L (no) 1996-06-28
PE49395A1 (es) 1996-01-06
CZ282567B6 (cs) 1997-08-13
CN1046515C (zh) 1999-11-17
DK0737194T3 (da) 1999-09-27
DE69416869T2 (de) 1999-07-01
NZ274915A (en) 1997-11-24
PL179435B1 (pl) 2000-09-29
AU699465B2 (en) 1998-12-03
NO962742D0 (no) 1996-06-28
EP0737194B1 (en) 1999-03-03
US6110919A (en) 2000-08-29
IL112118A0 (en) 1995-03-15
US5854239A (en) 1998-12-29
KR100197454B1 (ko) 1999-06-15
CZ188696A3 (en) 1996-10-16
TW369526B (en) 1999-09-11
WO1995018129A1 (en) 1995-07-06
AU8002194A (en) 1995-07-17
EP0737194A1 (en) 1996-10-16
IL112118A (en) 1998-10-30
JPH09500904A (ja) 1997-01-28
RU2124014C1 (ru) 1998-12-27
HU9601790D0 (en) 1996-09-30
JP2895630B2 (ja) 1999-05-24
HUT74682A (en) 1997-01-28
CO4230019A1 (es) 1995-10-19
BR9408450A (pt) 1997-08-05
CA2180263C (en) 2000-05-16
NO305600B1 (no) 1999-06-28
CN1139434A (zh) 1997-01-01
FI946140A (fi) 1995-06-30

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