ZA93436B - Benzopyran derivatives - Google Patents
Benzopyran derivativesInfo
- Publication number
- ZA93436B ZA93436B ZA93436A ZA93436A ZA93436B ZA 93436 B ZA93436 B ZA 93436B ZA 93436 A ZA93436 A ZA 93436A ZA 93436 A ZA93436 A ZA 93436A ZA 93436 B ZA93436 B ZA 93436B
- Authority
- ZA
- South Africa
- Prior art keywords
- represent
- hydroxy
- benzopyran derivatives
- hydrogen
- formula
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/10—Spiro-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pulmonology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrane Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP1081992 | 1992-01-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA93436B true ZA93436B (en) | 1993-08-25 |
Family
ID=11760967
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA93436A ZA93436B (en) | 1992-01-24 | 1993-01-21 | Benzopyran derivatives |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US5646308A (de) |
| EP (1) | EP0632033B1 (de) |
| JP (1) | JP3260458B2 (de) |
| KR (1) | KR100217167B1 (de) |
| CN (1) | CN1036918C (de) |
| AT (1) | ATE178601T1 (de) |
| AU (1) | AU3367393A (de) |
| CA (1) | CA2128603A1 (de) |
| DE (1) | DE69324354T2 (de) |
| DK (1) | DK0632033T3 (de) |
| ES (1) | ES2132217T3 (de) |
| GR (1) | GR3030581T3 (de) |
| SG (1) | SG52734A1 (de) |
| WO (1) | WO1993015068A1 (de) |
| ZA (1) | ZA93436B (de) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5428031A (en) * | 1991-12-03 | 1995-06-27 | Merck & Co., Inc. | Methods of treating cardiac arrhythmia |
| KR100241585B1 (ko) * | 1993-04-23 | 2000-03-02 | 나가야마 오사무 | 벤조피란 유도체 |
| KR0170534B1 (ko) * | 1993-11-10 | 1999-02-18 | 미즈노 시게루 | 크로만 유도체 및 그의 제약학적 용도 |
| DE69513295T2 (de) * | 1994-08-18 | 2000-06-08 | Merck & Co., Inc. | 2,3-dihydro-1-(2,2,2-trifluorethyl)-2-oxo-5-phenyl-1h-1,4-benzodiazepine |
| ES2193241T3 (es) * | 1995-06-07 | 2003-11-01 | Merck & Co Inc | Nuevas n-2-oxo2.3.4.5-tetrajodrp-1h-1,5-benzodiazepin-3-il)-3-amidas. |
| US5631251A (en) * | 1995-06-07 | 1997-05-20 | Merck & Co., Inc. | 5-cyclopropyl-1,4 benzodiazepine-2-ones |
| US5691331A (en) * | 1995-06-07 | 1997-11-25 | Merck & Co., Inc. | N-(2,4-Dioxo-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-3yl) -3- amides |
| US5700797A (en) * | 1995-06-07 | 1997-12-23 | Merck & Co, Inc. | N-(2,4-dioxo-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-3-yl)-3-amides |
| US5726171A (en) * | 1995-06-07 | 1998-03-10 | Merck & Co Inc | N-(1-alkyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo B! 1,4!diazepin-3yl)-acetamides |
| JP3076066B2 (ja) * | 1996-08-27 | 2000-08-14 | 塩野義製薬株式会社 | クロメン−３−カルボン酸誘導体 |
| FR2756284B1 (fr) * | 1996-11-26 | 2000-04-28 | Adir | Nouveaux derives du benzopyrane, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| TW533073B (en) | 1997-03-03 | 2003-05-21 | Chugai Pharmaceutical Co Ltd | Therapeutic agents for peripheral vascular disease |
| US6218411B1 (en) * | 1997-08-08 | 2001-04-17 | Chugai Seiyaku Kabushiki Kaisha | Therapeutics for diabetic complications |
| WO2000018754A1 (fr) * | 1998-09-30 | 2000-04-06 | Chugai Seiyaku Kabushiki Kaisha | Procedes de preparation de derives de benzopyranne 4-substitue |
| CZ20013076A3 (cs) * | 2000-08-29 | 2002-04-17 | Kuraray Co., Ltd. | Způsob výroby chromankarboxylové kyseliny |
| KR100602191B1 (ko) * | 2004-03-10 | 2006-07-19 | 한국화학연구원 | 5-라이폭시게네이즈 저해활성을 가지는2,2'-이중치환-3,4-디하이드로-7,8-이중치환-6-알킬아미노벤조피란 유도체 |
| WO2005105776A1 (en) * | 2004-05-05 | 2005-11-10 | F. Hoffmann-La Roche Ag | Arylsulfonyl benzodioxanes useful for modulation the 5-ht6 receptor, the 5-ht2areceptor or both |
| ATE512961T1 (de) | 2004-07-30 | 2011-07-15 | Torrent Pharmaceuticals Ltd | Amorphes nebivolol hydrochlorid und seine herstellung |
| DE602005019098D1 (de) * | 2004-12-21 | 2010-03-11 | Hoffmann La Roche | Tetralin- und indanderivate und deren anwendungen |
| KR20070088798A (ko) * | 2004-12-21 | 2007-08-29 | 에프. 호프만-라 로슈 아게 | 크로만 유도체 및 그의 5-ｈｔ 수용체 리간드로서의 용도 |
| KR100965190B1 (ko) | 2004-12-21 | 2010-06-24 | 에프. 호프만-라 로슈 아게 | 크로만 유도체 및 중추 신경계 장애의 치료에서 그의 용도 |
| BRPI0515835A (pt) * | 2004-12-21 | 2008-08-12 | Hoffmann La Roche | derivados de tetralina e de indano e seus usos |
| JP2008524277A (ja) * | 2004-12-21 | 2008-07-10 | エフ．ホフマン−ラ ロシュ アーゲー | テトラリン及びインダン誘導体、並びにそれらの５−ｈｔ拮抗薬としての使用 |
| KR100704009B1 (ko) * | 2005-08-30 | 2007-04-04 | 한국화학연구원 | 염증억제 활성을 가지는6-알킬아미노-2-메틸-2'-(ｎ-메틸치환술폰아미도)메틸-2ｈ-1-벤조피란 유도체 |
| CA2628173A1 (en) * | 2005-11-03 | 2007-05-10 | F. Hoffmann-La Roche Ag | Arylsulfonylchromans as 5-ht6 inhibitors indolylmaleimide derivatives as protein kinase inhibitors |
| CA2653758A1 (en) * | 2006-06-20 | 2007-12-27 | F. Hoffmann-La Roche Ag | Tetralin and indane derivatives and uses thereof |
| JP2009541249A (ja) * | 2006-06-20 | 2009-11-26 | エフ．ホフマン−ラ ロシュ アーゲー | アリールスルホニルナフタレン誘導体およびその使用 |
| WO2007147762A1 (en) * | 2006-06-20 | 2007-12-27 | F. Hoffmann-La Roche Ag | Arylsulfonamidyl tetralin derivatives and uses thereof |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH619701A5 (de) * | 1975-08-07 | 1980-10-15 | Bayer Ag | |
| JPS57167981A (en) * | 1981-04-08 | 1982-10-16 | Kowa Co | Benzopyran derivative |
| GB8911280D0 (en) * | 1989-05-17 | 1989-07-05 | Beecham Group Plc | Novel compounds |
| ATE161254T1 (de) * | 1990-07-27 | 1998-01-15 | Chugai Pharmaceutical Co Ltd | Benzopyranderivat |
-
1993
- 1993-01-21 ZA ZA93436A patent/ZA93436B/xx unknown
- 1993-01-22 JP JP00942193A patent/JP3260458B2/ja not_active Expired - Fee Related
- 1993-01-22 CN CN93102056A patent/CN1036918C/zh not_active Expired - Fee Related
- 1993-01-25 KR KR1019940702541A patent/KR100217167B1/ko not_active IP Right Cessation
- 1993-01-25 EP EP93902526A patent/EP0632033B1/de not_active Expired - Lifetime
- 1993-01-25 WO PCT/JP1993/000086 patent/WO1993015068A1/ja active IP Right Grant
- 1993-01-25 US US08/256,580 patent/US5646308A/en not_active Expired - Fee Related
- 1993-01-25 ES ES93902526T patent/ES2132217T3/es not_active Expired - Lifetime
- 1993-01-25 CA CA002128603A patent/CA2128603A1/en not_active Abandoned
- 1993-01-25 AU AU33673/93A patent/AU3367393A/en not_active Abandoned
- 1993-01-25 DE DE69324354T patent/DE69324354T2/de not_active Expired - Fee Related
- 1993-01-25 DK DK93902526T patent/DK0632033T3/da active
- 1993-01-25 SG SG1996008501A patent/SG52734A1/en unknown
- 1993-01-25 AT AT93902526T patent/ATE178601T1/de not_active IP Right Cessation
-
1999
- 1999-06-22 GR GR990401664T patent/GR3030581T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN1077954A (zh) | 1993-11-03 |
| US5646308A (en) | 1997-07-08 |
| KR950700277A (ko) | 1995-01-16 |
| KR100217167B1 (ko) | 1999-09-01 |
| EP0632033A1 (de) | 1995-01-04 |
| EP0632033B1 (de) | 1999-04-07 |
| DE69324354T2 (de) | 1999-11-25 |
| WO1993015068A1 (en) | 1993-08-05 |
| ES2132217T3 (es) | 1999-08-16 |
| DE69324354D1 (de) | 1999-05-12 |
| GR3030581T3 (en) | 1999-10-29 |
| EP0632033A4 (de) | 1995-02-01 |
| JPH05294954A (ja) | 1993-11-09 |
| JP3260458B2 (ja) | 2002-02-25 |
| CN1036918C (zh) | 1998-01-07 |
| CA2128603A1 (en) | 1993-08-05 |
| ATE178601T1 (de) | 1999-04-15 |
| AU3367393A (en) | 1993-09-01 |
| DK0632033T3 (da) | 1999-10-18 |
| SG52734A1 (en) | 1998-09-28 |
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