ZA92862B - Lipoxygenase-inhibiting hydroxamic acid and N-hydroxyurea derivatives. - Google Patents
Lipoxygenase-inhibiting hydroxamic acid and N-hydroxyurea derivatives.Info
- Publication number
- ZA92862B ZA92862B ZA92862A ZA92862A ZA92862B ZA 92862 B ZA92862 B ZA 92862B ZA 92862 A ZA92862 A ZA 92862A ZA 92862 A ZA92862 A ZA 92862A ZA 92862 B ZA92862 B ZA 92862B
- Authority
- ZA
- South Africa
- Prior art keywords
- hydrogen
- hydroxamic acid
- lipoxygenase
- alkenyl
- sulfur
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D307/10—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/14—Radicals substituted by nitrogen atoms not forming part of a nitro radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D307/18—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/22—Nitrogen atoms not forming part of a nitro radical
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Rheumatology (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Lubricants (AREA)
- Pyrane Compounds (AREA)
- Furan Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP3016325A JPH0730061B2 (ja) | 1991-02-07 | 1991-02-07 | ヒドロキサム酸誘導体および組成物 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA92862B true ZA92862B (en) | 1993-08-06 |
Family
ID=11913313
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA92862A ZA92862B (en) | 1991-02-07 | 1992-02-06 | Lipoxygenase-inhibiting hydroxamic acid and N-hydroxyurea derivatives. |
Country Status (21)
Country | Link |
---|---|
EP (1) | EP0570401B1 (xx) |
JP (1) | JPH0730061B2 (xx) |
KR (1) | KR930703279A (xx) |
AT (1) | ATE113942T1 (xx) |
AU (1) | AU648872B2 (xx) |
CA (1) | CA2101539A1 (xx) |
DE (1) | DE69200665T2 (xx) |
DK (1) | DK0570401T3 (xx) |
ES (1) | ES2063578T3 (xx) |
FI (1) | FI933492A (xx) |
HU (1) | HUT65539A (xx) |
IE (1) | IE920392A1 (xx) |
IL (1) | IL100846A0 (xx) |
MX (1) | MX9200519A (xx) |
MY (1) | MY134478A (xx) |
NO (1) | NO932815L (xx) |
NZ (1) | NZ241530A (xx) |
PT (1) | PT100093A (xx) |
TW (1) | TW222627B (xx) |
WO (1) | WO1992013848A1 (xx) |
ZA (1) | ZA92862B (xx) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5639782A (en) * | 1992-03-04 | 1997-06-17 | Center For Innovative Technology | Neolignan derivatives as platelet activating factor receptor antagonists and 5-lipoxygenase inhibitors |
WO1994001430A1 (en) | 1992-07-13 | 1994-01-20 | Cytomed, Inc. | 2,5-diaryl tetrahydro-thiophenes, -furans and analogs for the treatment of inflammatory and immune disorders |
US5434151A (en) * | 1992-08-24 | 1995-07-18 | Cytomed, Inc. | Compounds and methods for the treatment of disorders mediated by platelet activating factor or products of 5-lipoxygenase |
US5463083A (en) * | 1992-07-13 | 1995-10-31 | Cytomed, Inc. | Compounds and methods for the treatment of cardiovascular, inflammatory and immune disorders |
BR9508196A (pt) * | 1994-06-27 | 1997-09-02 | Cytomed Inc | Composto uso de compostos composição farmacêutica e processo para tratamento de doenças inflamatórias em hospedeiro |
US6201016B1 (en) * | 1994-06-27 | 2001-03-13 | Cytomed Incorporated | Compounds and methods for the treatment of cardiovascular, inflammatory and immune disorders |
US5750565A (en) | 1995-05-25 | 1998-05-12 | Cytomed, Inc. | Compounds and methods for the treatment of cardiovascular, inflammatory and immune disorders |
US5792776A (en) * | 1994-06-27 | 1998-08-11 | Cytomed, Inc., | Compounds and methods for the treatment of cardiovascular, inflammatory and immune disorders |
US5703093A (en) * | 1995-05-31 | 1997-12-30 | Cytomed, Inc. | Compounds and methods for the treatment of cardiovascular, inflammatory and immune disorders |
MX9701042A (es) * | 1996-02-07 | 1998-05-31 | Pfizer | Compuestos del acido hidroxamico. |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1044308A (en) * | 1964-04-28 | 1966-09-28 | Langbein Pfanhauser Werke Ag | Electrodeposition of bright copper |
US3393209A (en) * | 1965-10-04 | 1968-07-16 | Dow Chemical Co | Furfuryl and tetrahydrofurfuryl phenyl ureas |
JPS5742632B2 (xx) * | 1972-12-25 | 1982-09-09 | ||
EP0279263B1 (en) * | 1987-02-10 | 1993-08-04 | Abbott Laboratories | Indole, benzofuran, benzothiophene containing lipoxygenase inhibiting compounds |
GB2201008B (en) * | 1987-02-12 | 1991-10-23 | Stc Plc | Optical fibre cables |
-
1991
- 1991-02-07 JP JP3016325A patent/JPH0730061B2/ja not_active Expired - Fee Related
-
1992
- 1992-01-08 EP EP92903377A patent/EP0570401B1/en not_active Expired - Lifetime
- 1992-01-08 DE DE69200665T patent/DE69200665T2/de not_active Expired - Fee Related
- 1992-01-08 AU AU11736/92A patent/AU648872B2/en not_active Ceased
- 1992-01-08 ES ES92903377T patent/ES2063578T3/es not_active Expired - Lifetime
- 1992-01-08 DK DK92903377.7T patent/DK0570401T3/da active
- 1992-01-08 HU HU9302283A patent/HUT65539A/hu unknown
- 1992-01-08 KR KR1019930702342A patent/KR930703279A/ko not_active Application Discontinuation
- 1992-01-08 WO PCT/US1992/000027 patent/WO1992013848A1/en active IP Right Grant
- 1992-01-08 CA CA002101539A patent/CA2101539A1/en not_active Abandoned
- 1992-01-08 AT AT92903377T patent/ATE113942T1/de not_active IP Right Cessation
- 1992-01-23 TW TW081100484A patent/TW222627B/zh active
- 1992-02-02 IL IL100846A patent/IL100846A0/xx unknown
- 1992-02-05 NZ NZ241530A patent/NZ241530A/xx unknown
- 1992-02-05 PT PT100093A patent/PT100093A/pt not_active Application Discontinuation
- 1992-02-06 ZA ZA92862A patent/ZA92862B/xx unknown
- 1992-02-06 IE IE039292A patent/IE920392A1/en not_active Application Discontinuation
- 1992-02-06 MX MX9200519A patent/MX9200519A/es unknown
- 1992-02-07 MY MYPI92000189A patent/MY134478A/en unknown
-
1993
- 1993-08-06 NO NO93932815A patent/NO932815L/no unknown
- 1993-08-06 FI FI933492A patent/FI933492A/fi not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
DE69200665T2 (de) | 1995-04-06 |
JPH04257571A (ja) | 1992-09-11 |
HUT65539A (en) | 1994-06-28 |
JPH0730061B2 (ja) | 1995-04-05 |
AU1173692A (en) | 1992-09-07 |
ES2063578T3 (es) | 1995-01-01 |
MX9200519A (es) | 1992-08-31 |
NZ241530A (en) | 1994-06-27 |
NO932815L (no) | 1993-08-09 |
MY134478A (en) | 2007-12-31 |
IL100846A0 (en) | 1992-11-15 |
KR930703279A (ko) | 1993-11-29 |
FI933492A0 (fi) | 1993-08-06 |
AU648872B2 (en) | 1994-05-05 |
NO932815D0 (no) | 1993-08-06 |
ATE113942T1 (de) | 1994-11-15 |
IE920392A1 (en) | 1992-08-12 |
DE69200665D1 (de) | 1994-12-15 |
EP0570401B1 (en) | 1994-11-09 |
PT100093A (pt) | 1993-03-31 |
WO1992013848A1 (en) | 1992-08-20 |
DK0570401T3 (da) | 1994-12-05 |
FI933492A (fi) | 1993-08-06 |
TW222627B (xx) | 1994-04-21 |
CA2101539A1 (en) | 1992-08-08 |
HU9302283D0 (en) | 1993-10-28 |
EP0570401A1 (en) | 1993-11-24 |
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