FI933492A - Lipoxigenas inhiberande hydroxaminsyra- och n-hydroxiureaderivat - Google Patents

Lipoxigenas inhiberande hydroxaminsyra- och n-hydroxiureaderivat Download PDF

Info

Publication number
FI933492A
FI933492A FI933492A FI933492A FI933492A FI 933492 A FI933492 A FI 933492A FI 933492 A FI933492 A FI 933492A FI 933492 A FI933492 A FI 933492A FI 933492 A FI933492 A FI 933492A
Authority
FI
Finland
Prior art keywords
hydrogen
alkenyl
sulfur
alkyl
oxygen
Prior art date
Application number
FI933492A
Other languages
English (en)
Other versions
FI933492A0 (fi
Inventor
Rodney William Stevens
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of FI933492A0 publication Critical patent/FI933492A0/fi
Publication of FI933492A publication Critical patent/FI933492A/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D307/10—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/14—Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D307/18—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/22—Nitrogen atoms not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Lubricants (AREA)
  • Furan Compounds (AREA)
  • Pyrane Compounds (AREA)
FI933492A 1991-02-07 1993-08-06 Lipoxigenas inhiberande hydroxaminsyra- och n-hydroxiureaderivat FI933492A (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP3016325A JPH0730061B2 (ja) 1991-02-07 1991-02-07 ヒドロキサム酸誘導体および組成物
PCT/US1992/000027 WO1992013848A1 (en) 1991-02-07 1992-01-08 Lipoxygenase-inhibiting hydroxamic acid and n-hydroxyurea derivatives

Publications (2)

Publication Number Publication Date
FI933492A0 FI933492A0 (fi) 1993-08-06
FI933492A true FI933492A (fi) 1993-08-06

Family

ID=11913313

Family Applications (1)

Application Number Title Priority Date Filing Date
FI933492A FI933492A (fi) 1991-02-07 1993-08-06 Lipoxigenas inhiberande hydroxaminsyra- och n-hydroxiureaderivat

Country Status (21)

Country Link
EP (1) EP0570401B1 (fi)
JP (1) JPH0730061B2 (fi)
KR (1) KR930703279A (fi)
AT (1) ATE113942T1 (fi)
AU (1) AU648872B2 (fi)
CA (1) CA2101539A1 (fi)
DE (1) DE69200665T2 (fi)
DK (1) DK0570401T3 (fi)
ES (1) ES2063578T3 (fi)
FI (1) FI933492A (fi)
HU (1) HUT65539A (fi)
IE (1) IE920392A1 (fi)
IL (1) IL100846A0 (fi)
MX (1) MX9200519A (fi)
MY (1) MY134478A (fi)
NO (1) NO932815L (fi)
NZ (1) NZ241530A (fi)
PT (1) PT100093A (fi)
TW (1) TW222627B (fi)
WO (1) WO1992013848A1 (fi)
ZA (1) ZA92862B (fi)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5639782A (en) * 1992-03-04 1997-06-17 Center For Innovative Technology Neolignan derivatives as platelet activating factor receptor antagonists and 5-lipoxygenase inhibitors
US5434151A (en) * 1992-08-24 1995-07-18 Cytomed, Inc. Compounds and methods for the treatment of disorders mediated by platelet activating factor or products of 5-lipoxygenase
US5463083A (en) * 1992-07-13 1995-10-31 Cytomed, Inc. Compounds and methods for the treatment of cardiovascular, inflammatory and immune disorders
ES2152952T3 (es) 1992-07-13 2001-02-16 Millennium Pharm Inc 2,5-diaril tetrahidro-tiofenos, -furanos y analogos para el tratamiento de problemas inflamatorios e inmunes.
US6201016B1 (en) * 1994-06-27 2001-03-13 Cytomed Incorporated Compounds and methods for the treatment of cardiovascular, inflammatory and immune disorders
PL317873A1 (en) * 1994-06-27 1997-04-28 Cytomed Inc Compounds for and method of treating cardiovascular, inflammatory and immunological disorders
US5750565A (en) * 1995-05-25 1998-05-12 Cytomed, Inc. Compounds and methods for the treatment of cardiovascular, inflammatory and immune disorders
US5792776A (en) * 1994-06-27 1998-08-11 Cytomed, Inc., Compounds and methods for the treatment of cardiovascular, inflammatory and immune disorders
US5703093A (en) * 1995-05-31 1997-12-30 Cytomed, Inc. Compounds and methods for the treatment of cardiovascular, inflammatory and immune disorders
MX9701042A (es) * 1996-02-07 1998-05-31 Pfizer Compuestos del acido hidroxamico.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1044308A (en) * 1964-04-28 1966-09-28 Langbein Pfanhauser Werke Ag Electrodeposition of bright copper
US3393209A (en) * 1965-10-04 1968-07-16 Dow Chemical Co Furfuryl and tetrahydrofurfuryl phenyl ureas
JPS5742632B2 (fi) * 1972-12-25 1982-09-09
ES2059408T3 (es) * 1987-02-10 1994-11-16 Abbott Lab Un proceso para la preparacion de un compuesto.
GB2201008B (en) * 1987-02-12 1991-10-23 Stc Plc Optical fibre cables

Also Published As

Publication number Publication date
IL100846A0 (en) 1992-11-15
JPH0730061B2 (ja) 1995-04-05
AU1173692A (en) 1992-09-07
HUT65539A (en) 1994-06-28
DE69200665D1 (de) 1994-12-15
TW222627B (fi) 1994-04-21
KR930703279A (ko) 1993-11-29
NO932815L (no) 1993-08-09
ES2063578T3 (es) 1995-01-01
EP0570401A1 (en) 1993-11-24
IE920392A1 (en) 1992-08-12
DK0570401T3 (da) 1994-12-05
FI933492A0 (fi) 1993-08-06
AU648872B2 (en) 1994-05-05
MY134478A (en) 2007-12-31
NO932815D0 (no) 1993-08-06
ZA92862B (en) 1993-08-06
JPH04257571A (ja) 1992-09-11
PT100093A (pt) 1993-03-31
EP0570401B1 (en) 1994-11-09
MX9200519A (es) 1992-08-31
ATE113942T1 (de) 1994-11-15
CA2101539A1 (en) 1992-08-08
DE69200665T2 (de) 1995-04-06
WO1992013848A1 (en) 1992-08-20
NZ241530A (en) 1994-06-27
HU9302283D0 (en) 1993-10-28

Similar Documents

Publication Publication Date Title
FI955438A0 (fi) N-asyylisulfamidihappoesterit (tai -tioesterit), N-asyylisulfonamidit ja N-sulfonyylikarbamiinihappoesterit (tai -tioesterit) hyperkolesteroleemisina aineina
BR9107124A (pt) Novos derivados de acido hidroxamico e de n-hidroxiureia e seu uso
DK0640601T3 (da) Benzamidderivat
FI933492A (fi) Lipoxigenas inhiberande hydroxaminsyra- och n-hydroxiureaderivat
ATE110721T1 (de) 2-alkyl-3-benzoylbenzofurane und diese enthaltende pharmazeutische zusammensetzungen.
DE69411003D1 (de) Cycloalkylhydroxyharnstoffe und ihre verwendung als lipoxy-genase-inhibitoren
BR9306762A (pt) Derivados indolinila anti-inflamatórios da n-hidroxiuréia e do ácido n-hidroxámico
FI932188A (fi) Oktahydronaftalenoximderivat foer inhibering av kolesterolbiosyntesen, deras framstaellning och anvaendning
FI944848A (fi) Fenyylisubstituoidut sykloalkyylihydroksiureajohdannaiset, jotka inhiboivat lipoksygenaasia
DE3889820D1 (de) Sulfonamidderivate, Inhibitoren für das Aldose-Reduktase-Enzymsystem und diese enthaltende pharmazeutische Zusammenstellungen.

Legal Events

Date Code Title Description
FD Application lapsed