ZA925903B - Geneserine derivatives,processes for the preparation thereof and pharmaceutical compositions containing them - Google Patents

Geneserine derivatives,processes for the preparation thereof and pharmaceutical compositions containing them

Info

Publication number
ZA925903B
ZA925903B ZA925903A ZA925903A ZA925903B ZA 925903 B ZA925903 B ZA 925903B ZA 925903 A ZA925903 A ZA 925903A ZA 925903 A ZA925903 A ZA 925903A ZA 925903 B ZA925903 B ZA 925903B
Authority
ZA
South Africa
Prior art keywords
pct
group
geneserine
derivatives
processes
Prior art date
Application number
ZA925903A
Other languages
English (en)
Inventor
Paolo Chiesi
Chiesi Paolo
Maurizio Del Canale
Del Canale Maurizio
Vittorino Servadio
Servadio Vittorino
Eleonora Ghidini
Ghidini Eleonora
Original Assignee
Chiesi Farma Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiesi Farma Spa filed Critical Chiesi Farma Spa
Publication of ZA925903B publication Critical patent/ZA925903B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Neurology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pyrane Compounds (AREA)
  • Saccharide Compounds (AREA)
ZA925903A 1991-08-09 1992-08-06 Geneserine derivatives,processes for the preparation thereof and pharmaceutical compositions containing them ZA925903B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI912237A IT1251166B (it) 1991-08-09 1991-08-09 Derivati di geneserina,loro preparazione e composizioni farmaceutiche che li contengono

Publications (1)

Publication Number Publication Date
ZA925903B true ZA925903B (en) 1993-04-28

Family

ID=11360556

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA925903A ZA925903B (en) 1991-08-09 1992-08-06 Geneserine derivatives,processes for the preparation thereof and pharmaceutical compositions containing them

Country Status (20)

Country Link
US (1) US5538968A (xx)
EP (1) EP0599890B1 (xx)
JP (1) JP3172185B2 (xx)
KR (1) KR100225927B1 (xx)
AT (1) ATE151426T1 (xx)
AU (1) AU659865B2 (xx)
CA (1) CA2115250A1 (xx)
CZ (1) CZ281018B6 (xx)
DE (1) DE69218949T2 (xx)
DK (1) DK0599890T3 (xx)
ES (1) ES2101858T3 (xx)
FI (1) FI107532B (xx)
GR (1) GR3023838T3 (xx)
HK (1) HK1006714A1 (xx)
HU (1) HU222774B1 (xx)
IT (1) IT1251166B (xx)
NO (1) NO303175B1 (xx)
NZ (1) NZ243869A (xx)
WO (1) WO1993003041A1 (xx)
ZA (1) ZA925903B (xx)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1023297A1 (en) * 1997-10-10 2000-08-02 CHIESI FARMACEUTICI S.p.A. A process for the preparation of aminocarbonyl derivatives of geneseroline having selective brain anticholinesterase activity
DE19853487A1 (de) * 1998-11-19 2000-05-25 Fumapharm Ag Muri Verwendung von Dialkylfumaraten
DE10000577A1 (de) * 2000-01-10 2001-07-26 Fumapharm Ag Muri Verwendung von Fumarsäurederivaten zur Behandlung mitochondrialer Krankheiten
CZ304198B6 (cs) * 2001-01-12 2013-12-27 Fumapharm Ag Amidy kyseliny fumarové
DE10101307A1 (de) * 2001-01-12 2002-08-01 Fumapharm Ag Muri Fumarsäurederivate als NF-kappaB-Inhibitor
PL1663197T3 (pl) 2003-09-09 2008-09-30 Biogen Idec Int Gmbh Zastosowanie pochodnych kwasu fumarowego do leczenia niewydolności serca oraz astmy
WO2005042475A2 (en) * 2003-10-21 2005-05-12 Sention, Inc. Carbamoyl esters that inhibit cholinesterase and release pharmacologically active agents
JP2010518010A (ja) * 2007-02-02 2010-05-27 コルシド・ファーマシューティカルズ・インコーポレイテッド コリンエステラーゼを阻害する化合物
LT2653873T (lt) 2007-02-08 2022-10-10 Biogen Ma Inc. Kompozicijos ir naudojimas, skirti išsėtinei sklerozei gydyti
ES2599227T3 (es) * 2007-02-08 2017-01-31 Biogen Ma Inc. Neuroprotección en enfermedades desmielinizantes
US20090048229A1 (en) * 2007-07-18 2009-02-19 Rupniak Nadia M J Methods for promoting wakefulness
US8593728B2 (en) * 2009-02-19 2013-11-26 Toyota Motor Engineering & Manufacturing North America, Inc. Multilayer photonic structures
WO2011100373A1 (en) 2010-02-09 2011-08-18 The Johns Hopkins University Methods and compositions for improving cognitive function
US10154988B2 (en) 2012-11-14 2018-12-18 The Johns Hopkins University Methods and compositions for treating schizophrenia
NZ631337A (en) 2013-03-14 2017-01-27 Alkermes Pharma Ireland Ltd Prodrugs of fumarates and their use in treating various diseases
US8669281B1 (en) 2013-03-14 2014-03-11 Alkermes Pharma Ireland Limited Prodrugs of fumarates and their use in treating various diseases
EP3827820A1 (en) 2013-03-15 2021-06-02 The Johns Hopkins University Brivaracetam for improving cognitive function
JP6433482B2 (ja) 2013-03-15 2018-12-05 エージンバイオ， インコーポレイテッド 認知機能を改善するための方法および組成物
AU2015218587B2 (en) 2014-02-24 2017-04-27 Alkermes Pharma Ireland Limited Sulfonamide and sulfinamide prodrugs of fumarates and their use in treating various diseases
WO2016191288A1 (en) 2015-05-22 2016-12-01 Agenebio, Inc. Extended release pharmaceutical compositions of levetiracetam

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2374908A1 (fr) * 1976-12-21 1978-07-21 Theranol Lab Medicament constitue par l'association optimale d'une substance vagomimetique, le salicylate d'amine-oxyde d'eserine, et d'une substance potentialisant la secretion gastrique, le chlorhydrate d'acide glutamique
IT1199076B (it) * 1984-03-01 1988-12-30 Consiglio Nazionale Ricerche Derivati della fisostigmina con proprieta'di inibizione della aceticolinesterasi e relativo procedimento di produzione
IT1225462B (it) * 1987-04-03 1990-11-14 Mediolanum Farmaceutici Srl Sali organici di derivati della fisostigmina

Also Published As

Publication number Publication date
KR100225927B1 (ko) 1999-10-15
FI940573A0 (fi) 1994-02-08
DE69218949D1 (de) 1997-05-15
DK0599890T3 (da) 1997-10-20
DE69218949T2 (de) 1997-09-18
NO940415L (no) 1994-04-06
JPH06509572A (ja) 1994-10-27
US5538968A (en) 1996-07-23
NZ243869A (en) 1994-03-25
EP0599890B1 (en) 1997-04-09
EP0599890A1 (en) 1994-06-08
HU9400353D0 (en) 1994-06-28
IT1251166B (it) 1995-05-04
FI107532B (fi) 2001-08-31
CA2115250A1 (en) 1993-02-18
HUT70414A (en) 1995-10-30
NO940415D0 (no) 1994-02-08
FI940573A (fi) 1994-03-28
ITMI912237A1 (it) 1993-02-10
ITMI912237A0 (it) 1991-08-09
ES2101858T3 (es) 1997-07-16
GR3023838T3 (en) 1997-09-30
HK1006714A1 (en) 1999-03-12
AU2387692A (en) 1993-03-02
HU222774B1 (hu) 2003-10-28
NO303175B1 (no) 1998-06-08
JP3172185B2 (ja) 2001-06-04
CZ26294A3 (en) 1994-07-13
ATE151426T1 (de) 1997-04-15
AU659865B2 (en) 1995-06-01
CZ281018B6 (cs) 1996-05-15
WO1993003041A1 (en) 1993-02-18

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