ATE151426T1 - Generserin-derivate als cholinesterase-hemmer - Google Patents
Generserin-derivate als cholinesterase-hemmerInfo
- Publication number
- ATE151426T1 ATE151426T1 AT92916772T AT92916772T ATE151426T1 AT E151426 T1 ATE151426 T1 AT E151426T1 AT 92916772 T AT92916772 T AT 92916772T AT 92916772 T AT92916772 T AT 92916772T AT E151426 T1 ATE151426 T1 AT E151426T1
- Authority
- AT
- Austria
- Prior art keywords
- pct
- group
- sec
- generserin
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Neurology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pyrane Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI912237A IT1251166B (it) | 1991-08-09 | 1991-08-09 | Derivati di geneserina,loro preparazione e composizioni farmaceutiche che li contengono |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE151426T1 true ATE151426T1 (de) | 1997-04-15 |
Family
ID=11360556
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT92916772T ATE151426T1 (de) | 1991-08-09 | 1992-08-04 | Generserin-derivate als cholinesterase-hemmer |
Country Status (20)
Country | Link |
---|---|
US (1) | US5538968A (de) |
EP (1) | EP0599890B1 (de) |
JP (1) | JP3172185B2 (de) |
KR (1) | KR100225927B1 (de) |
AT (1) | ATE151426T1 (de) |
AU (1) | AU659865B2 (de) |
CA (1) | CA2115250A1 (de) |
CZ (1) | CZ281018B6 (de) |
DE (1) | DE69218949T2 (de) |
DK (1) | DK0599890T3 (de) |
ES (1) | ES2101858T3 (de) |
FI (1) | FI107532B (de) |
GR (1) | GR3023838T3 (de) |
HK (1) | HK1006714A1 (de) |
HU (1) | HU222774B1 (de) |
IT (1) | IT1251166B (de) |
NO (1) | NO303175B1 (de) |
NZ (1) | NZ243869A (de) |
WO (1) | WO1993003041A1 (de) |
ZA (1) | ZA925903B (de) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ503773A (en) * | 1997-10-10 | 2002-05-31 | Chiese Farmaceutici S | A process for the preparation of aminocarbonyl derivatives of geneseroline having selective brain anticholinesterase activity |
DE19853487A1 (de) | 1998-11-19 | 2000-05-25 | Fumapharm Ag Muri | Verwendung von Dialkylfumaraten |
DE10000577A1 (de) * | 2000-01-10 | 2001-07-26 | Fumapharm Ag Muri | Verwendung von Fumarsäurederivaten zur Behandlung mitochondrialer Krankheiten |
JP2004523511A (ja) * | 2001-01-12 | 2004-08-05 | フーマファーム アーゲー | フマル酸アミド類 |
DE10101307A1 (de) * | 2001-01-12 | 2002-08-01 | Fumapharm Ag Muri | Fumarsäurederivate als NF-kappaB-Inhibitor |
BRPI0410805A (pt) | 2003-09-09 | 2006-06-27 | Fumapharm Ag | uso de derivados do ácido fumárico para tratamento da insuficiência cardìaca e asma |
US7897639B2 (en) * | 2003-10-21 | 2011-03-01 | Colucid Pharmaceuticals, Inc. | Carbamoyl esters that inhibit cholinesterase and release pharmacologically active agents |
EP2125709A2 (de) * | 2007-02-02 | 2009-12-02 | Colucid Pharmaceuticals, Inc. | Verbindungen zur hemmung von cholinesterase |
EP3135282A1 (de) * | 2007-02-08 | 2017-03-01 | Biogen MA Inc. | Nervenschutz bei entmarkungserkrankungen |
HRP20220902T3 (hr) | 2007-02-08 | 2022-10-14 | Biogen Ma Inc. | Pripravci i njihova upotreba u liječenju multiple skleroze |
US20090048229A1 (en) * | 2007-07-18 | 2009-02-19 | Rupniak Nadia M J | Methods for promoting wakefulness |
US8593728B2 (en) * | 2009-02-19 | 2013-11-26 | Toyota Motor Engineering & Manufacturing North America, Inc. | Multilayer photonic structures |
EA037187B1 (ru) | 2010-02-09 | 2021-02-17 | Дзе Джонс Хопкинс Юниверсити | Способ и композиция для лечения когнитивного расстройства |
US10154988B2 (en) | 2012-11-14 | 2018-12-18 | The Johns Hopkins University | Methods and compositions for treating schizophrenia |
HUE040044T2 (hu) | 2013-03-14 | 2019-02-28 | Alkermes Pharma Ireland Ltd | Fumarátok prodrugjai, és azok alkalmazása különbözõ betegségek kezelésében |
US8669281B1 (en) | 2013-03-14 | 2014-03-11 | Alkermes Pharma Ireland Limited | Prodrugs of fumarates and their use in treating various diseases |
WO2014144663A1 (en) | 2013-03-15 | 2014-09-18 | The Johns Hopkins University | Methods and compositions for improving cognitive function |
WO2014144801A1 (en) | 2013-03-15 | 2014-09-18 | Agenebio Inc. | Methods and compositions for improving cognitive function |
US9604922B2 (en) | 2014-02-24 | 2017-03-28 | Alkermes Pharma Ireland Limited | Sulfonamide and sulfinamide prodrugs of fumarates and their use in treating various diseases |
US10925834B2 (en) | 2015-05-22 | 2021-02-23 | Agenebio, Inc. | Extended release pharmaceutical compositions of levetiracetam |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2374908A1 (fr) * | 1976-12-21 | 1978-07-21 | Theranol Lab | Medicament constitue par l'association optimale d'une substance vagomimetique, le salicylate d'amine-oxyde d'eserine, et d'une substance potentialisant la secretion gastrique, le chlorhydrate d'acide glutamique |
IT1199076B (it) * | 1984-03-01 | 1988-12-30 | Consiglio Nazionale Ricerche | Derivati della fisostigmina con proprieta'di inibizione della aceticolinesterasi e relativo procedimento di produzione |
IT1225462B (it) * | 1987-04-03 | 1990-11-14 | Mediolanum Farmaceutici Srl | Sali organici di derivati della fisostigmina |
-
1991
- 1991-08-09 IT ITMI912237A patent/IT1251166B/it active IP Right Grant
-
1992
- 1992-08-04 ES ES92916772T patent/ES2101858T3/es not_active Expired - Lifetime
- 1992-08-04 EP EP92916772A patent/EP0599890B1/de not_active Expired - Lifetime
- 1992-08-04 KR KR1019940700410A patent/KR100225927B1/ko not_active IP Right Cessation
- 1992-08-04 AU AU23876/92A patent/AU659865B2/en not_active Ceased
- 1992-08-04 WO PCT/EP1992/001762 patent/WO1993003041A1/en active IP Right Grant
- 1992-08-04 DE DE69218949T patent/DE69218949T2/de not_active Expired - Fee Related
- 1992-08-04 US US08/193,154 patent/US5538968A/en not_active Expired - Fee Related
- 1992-08-04 JP JP50327893A patent/JP3172185B2/ja not_active Expired - Fee Related
- 1992-08-04 CZ CZ94262A patent/CZ281018B6/cs not_active IP Right Cessation
- 1992-08-04 HU HU9400353A patent/HU222774B1/hu not_active IP Right Cessation
- 1992-08-04 DK DK92916772.4T patent/DK0599890T3/da active
- 1992-08-04 AT AT92916772T patent/ATE151426T1/de not_active IP Right Cessation
- 1992-08-04 CA CA002115250A patent/CA2115250A1/en not_active Abandoned
- 1992-08-06 ZA ZA925903A patent/ZA925903B/xx unknown
- 1992-08-06 NZ NZ243869A patent/NZ243869A/en unknown
-
1994
- 1994-02-08 NO NO940415A patent/NO303175B1/no unknown
- 1994-02-08 FI FI940573A patent/FI107532B/fi active
-
1997
- 1997-06-19 GR GR970401476T patent/GR3023838T3/el unknown
-
1998
- 1998-06-23 HK HK98106098A patent/HK1006714A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
JPH06509572A (ja) | 1994-10-27 |
KR100225927B1 (ko) | 1999-10-15 |
US5538968A (en) | 1996-07-23 |
NO940415L (no) | 1994-04-06 |
AU659865B2 (en) | 1995-06-01 |
IT1251166B (it) | 1995-05-04 |
ITMI912237A1 (it) | 1993-02-10 |
CZ26294A3 (en) | 1994-07-13 |
DE69218949T2 (de) | 1997-09-18 |
FI940573A (fi) | 1994-03-28 |
FI107532B (fi) | 2001-08-31 |
ZA925903B (en) | 1993-04-28 |
NO940415D0 (no) | 1994-02-08 |
JP3172185B2 (ja) | 2001-06-04 |
HU222774B1 (hu) | 2003-10-28 |
HU9400353D0 (en) | 1994-06-28 |
WO1993003041A1 (en) | 1993-02-18 |
GR3023838T3 (en) | 1997-09-30 |
HK1006714A1 (en) | 1999-03-12 |
ITMI912237A0 (it) | 1991-08-09 |
DK0599890T3 (da) | 1997-10-20 |
DE69218949D1 (de) | 1997-05-15 |
EP0599890A1 (de) | 1994-06-08 |
CA2115250A1 (en) | 1993-02-18 |
CZ281018B6 (cs) | 1996-05-15 |
ES2101858T3 (es) | 1997-07-16 |
EP0599890B1 (de) | 1997-04-09 |
NO303175B1 (no) | 1998-06-08 |
FI940573A0 (fi) | 1994-02-08 |
AU2387692A (en) | 1993-03-02 |
NZ243869A (en) | 1994-03-25 |
HUT70414A (en) | 1995-10-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification | ||
REN | Ceased due to non-payment of the annual fee |