DK0599890T3 - Geneserinderivater som cholinesteraseinhibitorer - Google Patents

Geneserinderivater som cholinesteraseinhibitorer

Info

Publication number
DK0599890T3
DK0599890T3 DK92916772.4T DK92916772T DK0599890T3 DK 0599890 T3 DK0599890 T3 DK 0599890T3 DK 92916772 T DK92916772 T DK 92916772T DK 0599890 T3 DK0599890 T3 DK 0599890T3
Authority
DK
Denmark
Prior art keywords
pct
group
sec
geneserine
derivatives
Prior art date
Application number
DK92916772.4T
Other languages
English (en)
Inventor
Paolo Chiesi
Canale Maurizio Del
Vittorino Servadio
Eleonora Ghidini
Original Assignee
Chiesi Farma Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiesi Farma Spa filed Critical Chiesi Farma Spa
Application granted granted Critical
Publication of DK0599890T3 publication Critical patent/DK0599890T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Neurology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pyrane Compounds (AREA)
  • Saccharide Compounds (AREA)
DK92916772.4T 1991-08-09 1992-08-04 Geneserinderivater som cholinesteraseinhibitorer DK0599890T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI912237A IT1251166B (it) 1991-08-09 1991-08-09 Derivati di geneserina,loro preparazione e composizioni farmaceutiche che li contengono

Publications (1)

Publication Number Publication Date
DK0599890T3 true DK0599890T3 (da) 1997-10-20

Family

ID=11360556

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92916772.4T DK0599890T3 (da) 1991-08-09 1992-08-04 Geneserinderivater som cholinesteraseinhibitorer

Country Status (20)

Country Link
US (1) US5538968A (da)
EP (1) EP0599890B1 (da)
JP (1) JP3172185B2 (da)
KR (1) KR100225927B1 (da)
AT (1) ATE151426T1 (da)
AU (1) AU659865B2 (da)
CA (1) CA2115250A1 (da)
CZ (1) CZ281018B6 (da)
DE (1) DE69218949T2 (da)
DK (1) DK0599890T3 (da)
ES (1) ES2101858T3 (da)
FI (1) FI107532B (da)
GR (1) GR3023838T3 (da)
HK (1) HK1006714A1 (da)
HU (1) HU222774B1 (da)
IT (1) IT1251166B (da)
NO (1) NO303175B1 (da)
NZ (1) NZ243869A (da)
WO (1) WO1993003041A1 (da)
ZA (1) ZA925903B (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU750964B2 (en) * 1997-10-10 2002-08-01 Chiesi Farmaceutici S.P.A. A process for the preparation of aminocarbonyl derivatives of geneseroline having selective brain anticholinesterase activity
DE19853487A1 (de) * 1998-11-19 2000-05-25 Fumapharm Ag Muri Verwendung von Dialkylfumaraten
DE10000577A1 (de) * 2000-01-10 2001-07-26 Fumapharm Ag Muri Verwendung von Fumarsäurederivaten zur Behandlung mitochondrialer Krankheiten
PL392748A1 (pl) 2001-01-12 2011-05-09 Fumapharm Ag Amidy kwasu fumarowego
DE10101307A1 (de) * 2001-01-12 2002-08-01 Fumapharm Ag Muri Fumarsäurederivate als NF-kappaB-Inhibitor
US20070027076A1 (en) 2003-09-09 2007-02-01 Fumapham Ag Use of fumaric acid derivatives for treating cardiac insufficiency, and asthma
CA2543322A1 (en) * 2003-10-21 2005-05-12 Sention, Inc. Carbamoyl esters that inhibit cholinesterase and release pharmacologically active agents
CA2677241A1 (en) * 2007-02-02 2008-08-14 Colucid Pharmaceuticals, Inc. Compounds that inhibit cholinesterase
EP2139467B1 (en) * 2007-02-08 2016-09-21 Biogen MA Inc. Neuroprotection in demyelinating diseases
PL2137537T3 (pl) 2007-02-08 2013-10-31 Biogen Ma Inc Kompozycje i zastosowania do leczenia stwardnienia rozsianego
WO2009011901A2 (en) * 2007-07-18 2009-01-22 Colucid Pharmaceuticals, Inc. Methods for promoting wakefulness
US8593728B2 (en) * 2009-02-19 2013-11-26 Toyota Motor Engineering & Manufacturing North America, Inc. Multilayer photonic structures
CN109662964A (zh) 2010-02-09 2019-04-23 约翰斯.霍普金斯大学 用于改善认知功能的方法和组合物
CA2891122C (en) 2012-11-14 2021-07-20 The Johns Hopkins University Methods and compositions for treating schizophrenia
US8669281B1 (en) 2013-03-14 2014-03-11 Alkermes Pharma Ireland Limited Prodrugs of fumarates and their use in treating various diseases
ES2683355T3 (es) 2013-03-14 2018-09-26 Alkermes Pharma Ireland Limited Profármacos de fumaratos y su uso en el tratamiento de diversas enfermedades
US10806717B2 (en) 2013-03-15 2020-10-20 The Johns Hopkins University Methods and compositions for improving cognitive function
AU2014228512A1 (en) 2013-03-15 2015-10-01 Agenebio, Inc. Methods and compositions for improving cognitive function
NZ723269A (en) 2014-02-24 2017-04-28 Alkermes Pharma Ireland Ltd Sulfonamide and sulfinamide prodrugs of fumarates and their use in treating various diseases
CA2986598C (en) 2015-05-22 2023-09-26 Agenebio, Inc. Extended release pharmaceutical compositions of levetiracetam

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2374908A1 (fr) * 1976-12-21 1978-07-21 Theranol Lab Medicament constitue par l'association optimale d'une substance vagomimetique, le salicylate d'amine-oxyde d'eserine, et d'une substance potentialisant la secretion gastrique, le chlorhydrate d'acide glutamique
IT1199076B (it) * 1984-03-01 1988-12-30 Consiglio Nazionale Ricerche Derivati della fisostigmina con proprieta'di inibizione della aceticolinesterasi e relativo procedimento di produzione
IT1225462B (it) * 1987-04-03 1990-11-14 Mediolanum Farmaceutici Srl Sali organici di derivati della fisostigmina

Also Published As

Publication number Publication date
KR100225927B1 (ko) 1999-10-15
JP3172185B2 (ja) 2001-06-04
CA2115250A1 (en) 1993-02-18
EP0599890B1 (en) 1997-04-09
FI940573A0 (fi) 1994-02-08
FI940573A (fi) 1994-03-28
ATE151426T1 (de) 1997-04-15
NO940415D0 (no) 1994-02-08
ITMI912237A0 (it) 1991-08-09
WO1993003041A1 (en) 1993-02-18
DE69218949T2 (de) 1997-09-18
JPH06509572A (ja) 1994-10-27
HU222774B1 (hu) 2003-10-28
HUT70414A (en) 1995-10-30
AU659865B2 (en) 1995-06-01
HU9400353D0 (en) 1994-06-28
FI107532B (fi) 2001-08-31
ES2101858T3 (es) 1997-07-16
AU2387692A (en) 1993-03-02
US5538968A (en) 1996-07-23
NZ243869A (en) 1994-03-25
NO940415L (no) 1994-04-06
DE69218949D1 (de) 1997-05-15
ZA925903B (en) 1993-04-28
CZ26294A3 (en) 1994-07-13
EP0599890A1 (en) 1994-06-08
IT1251166B (it) 1995-05-04
CZ281018B6 (cs) 1996-05-15
GR3023838T3 (en) 1997-09-30
HK1006714A1 (en) 1999-03-12
ITMI912237A1 (it) 1993-02-10
NO303175B1 (no) 1998-06-08

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