ITMI912237A0 - Derivati di geneserina loro preparazione e composizioni farmaceutiche che li contengono - Google Patents
Derivati di geneserina loro preparazione e composizioni farmaceutiche che li contengonoInfo
- Publication number
- ITMI912237A0 ITMI912237A0 IT91MI2237A ITMI912237A ITMI912237A0 IT MI912237 A0 ITMI912237 A0 IT MI912237A0 IT 91MI2237 A IT91MI2237 A IT 91MI2237A IT MI912237 A ITMI912237 A IT MI912237A IT MI912237 A0 ITMI912237 A0 IT MI912237A0
- Authority
- IT
- Italy
- Prior art keywords
- geneserin
- derivatives
- contain
- preparation
- pharmaceutical compositions
- Prior art date
Links
- CNBHDDBNEKKMJH-UHFFFAOYSA-N (2,4a,9-trimethyl-4,9a-dihydro-3h-oxazino[6,5-b]indol-6-yl) n-methylcarbamate Chemical class O1N(C)CCC2(C)C3=CC(OC(=O)NC)=CC=C3N(C)C21 CNBHDDBNEKKMJH-UHFFFAOYSA-N 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Priority Applications (20)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI912237A IT1251166B (it) | 1991-08-09 | 1991-08-09 | Derivati di geneserina,loro preparazione e composizioni farmaceutiche che li contengono |
ES92916772T ES2101858T3 (es) | 1991-08-09 | 1992-08-04 | Derivados de geneserina como inhibidores de colinesterasa. |
JP50327893A JP3172185B2 (ja) | 1991-08-09 | 1992-08-04 | コリンエステラーゼ阻害剤としてのゲネセリン誘導体 |
AT92916772T ATE151426T1 (de) | 1991-08-09 | 1992-08-04 | Generserin-derivate als cholinesterase-hemmer |
EP92916772A EP0599890B1 (en) | 1991-08-09 | 1992-08-04 | Geneserine derivatives as cholinesterase inhibitors |
HU9400353A HU222774B1 (hu) | 1991-08-09 | 1992-08-04 | Kolinészteráz-inhibitor hatású geneszerinszármazékok és ezeket tartalmazó gyógyszerkészítmények |
CZ94262A CZ281018B6 (cs) | 1991-08-09 | 1992-08-04 | Deriváty geneserinu a farmaceutické prostředky s jejich obsahem |
US08/193,154 US5538968A (en) | 1991-08-09 | 1992-08-04 | Geneserine derivatives processes as cholinesterase inhibitors |
CA002115250A CA2115250A1 (en) | 1991-08-09 | 1992-08-04 | Geneserine derivatives as cholinesterase inhibitors |
KR1019940700410A KR100225927B1 (ko) | 1991-08-09 | 1992-08-04 | 콜린에스테라제 저해제로서의 제네세린 유도체 |
DK92916772.4T DK0599890T3 (da) | 1991-08-09 | 1992-08-04 | Geneserinderivater som cholinesteraseinhibitorer |
AU23876/92A AU659865B2 (en) | 1991-08-09 | 1992-08-04 | Geneserine derivatives as cholinesterase inhibitors |
DE69218949T DE69218949T2 (de) | 1991-08-09 | 1992-08-04 | Generserin-derivate als cholinesterase-hemmer |
PCT/EP1992/001762 WO1993003041A1 (en) | 1991-08-09 | 1992-08-04 | Geneserine derivatives as cholinesterase inhibitors |
NZ243869A NZ243869A (en) | 1991-08-09 | 1992-08-06 | Geneserine derivatives and pharmaceutical compositions thereof |
ZA925903A ZA925903B (en) | 1991-08-09 | 1992-08-06 | Geneserine derivatives,processes for the preparation thereof and pharmaceutical compositions containing them |
FI940573A FI107532B (fi) | 1991-08-09 | 1994-02-08 | Menetelmä lääkeaineena käyttökelpoisten geneseriinijohdannaisten valmistamiseksi |
NO940415A NO303175B1 (no) | 1991-08-09 | 1994-02-08 | Geneserinderivater som kolinesterase-hemmere |
GR970401476T GR3023838T3 (en) | 1991-08-09 | 1997-06-19 | Geneserine derivatives as cholinesterase inhibitors. |
HK98106098A HK1006714A1 (en) | 1991-08-09 | 1998-06-23 | Geneserine derivatives as cholinesterase inhibitors |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI912237A IT1251166B (it) | 1991-08-09 | 1991-08-09 | Derivati di geneserina,loro preparazione e composizioni farmaceutiche che li contengono |
Publications (3)
Publication Number | Publication Date |
---|---|
ITMI912237A0 true ITMI912237A0 (it) | 1991-08-09 |
ITMI912237A1 ITMI912237A1 (it) | 1993-02-10 |
IT1251166B IT1251166B (it) | 1995-05-04 |
Family
ID=11360556
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ITMI912237A IT1251166B (it) | 1991-08-09 | 1991-08-09 | Derivati di geneserina,loro preparazione e composizioni farmaceutiche che li contengono |
Country Status (20)
Country | Link |
---|---|
US (1) | US5538968A (it) |
EP (1) | EP0599890B1 (it) |
JP (1) | JP3172185B2 (it) |
KR (1) | KR100225927B1 (it) |
AT (1) | ATE151426T1 (it) |
AU (1) | AU659865B2 (it) |
CA (1) | CA2115250A1 (it) |
CZ (1) | CZ281018B6 (it) |
DE (1) | DE69218949T2 (it) |
DK (1) | DK0599890T3 (it) |
ES (1) | ES2101858T3 (it) |
FI (1) | FI107532B (it) |
GR (1) | GR3023838T3 (it) |
HK (1) | HK1006714A1 (it) |
HU (1) | HU222774B1 (it) |
IT (1) | IT1251166B (it) |
NO (1) | NO303175B1 (it) |
NZ (1) | NZ243869A (it) |
WO (1) | WO1993003041A1 (it) |
ZA (1) | ZA925903B (it) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1999019329A1 (en) * | 1997-10-10 | 1999-04-22 | Chiesi Farmaceutici S.P.A. | A process for the preparation of aminocarbonyl derivatives of geneseroline having selective brain anticholinesterase activity |
DE19853487A1 (de) * | 1998-11-19 | 2000-05-25 | Fumapharm Ag Muri | Verwendung von Dialkylfumaraten |
DE10000577A1 (de) * | 2000-01-10 | 2001-07-26 | Fumapharm Ag Muri | Verwendung von Fumarsäurederivaten zur Behandlung mitochondrialer Krankheiten |
PL392748A1 (pl) * | 2001-01-12 | 2011-05-09 | Fumapharm Ag | Amidy kwasu fumarowego |
DE10101307A1 (de) * | 2001-01-12 | 2002-08-01 | Fumapharm Ag Muri | Fumarsäurederivate als NF-kappaB-Inhibitor |
ES2297461T3 (es) | 2003-09-09 | 2008-05-01 | Fumapharm Ag | Uso de derivados del acido fumarico para tratar la insuficiencia cardiaca y el asma. |
CN1898201A (zh) * | 2003-10-21 | 2007-01-17 | 森蒂有限公司 | 可抑制胆碱酯酶和释放药理学活性试剂的氨基甲酸酯 |
US8101782B2 (en) * | 2007-02-02 | 2012-01-24 | Colucid Pharmaceuticals, Inc. | Compounds that inhibit cholinesterase |
US20110112196A1 (en) | 2007-02-08 | 2011-05-12 | Matvey E Lukashev | Nrf2 screening assays and related methods and compositions |
EP2139467B1 (en) * | 2007-02-08 | 2016-09-21 | Biogen MA Inc. | Neuroprotection in demyelinating diseases |
AU2008276459A1 (en) * | 2007-07-18 | 2009-01-22 | Colucid Pharmaceuticals, Inc. | Methods for promoting wakefulness |
US8593728B2 (en) * | 2009-02-19 | 2013-11-26 | Toyota Motor Engineering & Manufacturing North America, Inc. | Multilayer photonic structures |
CA2789014C (en) | 2010-02-09 | 2019-01-15 | Michela Gallagher | Methods and compositions for improving cognitive function |
JP6440625B2 (ja) | 2012-11-14 | 2018-12-19 | ザ・ジョンズ・ホプキンス・ユニバーシティー | 精神分裂病を処置するための方法および組成物 |
DK2970101T3 (en) | 2013-03-14 | 2018-08-20 | Alkermes Pharma Ireland Ltd | PRO-DRUGS OF FUMARATES AND THEIR USE IN TREATING DIFFERENT DISEASES |
US8669281B1 (en) | 2013-03-14 | 2014-03-11 | Alkermes Pharma Ireland Limited | Prodrugs of fumarates and their use in treating various diseases |
WO2014144663A1 (en) | 2013-03-15 | 2014-09-18 | The Johns Hopkins University | Methods and compositions for improving cognitive function |
CA2904767C (en) | 2013-03-15 | 2022-06-21 | Agenebio, Inc. | Methods and compositions for improving cognitive function |
CA2940845C (en) | 2014-02-24 | 2019-09-24 | Alkermes Pharma Ireland Limited | Sulfonamide and sulfinamide prodrugs of fumarates and their use in treating various diseases |
WO2016191288A1 (en) | 2015-05-22 | 2016-12-01 | Agenebio, Inc. | Extended release pharmaceutical compositions of levetiracetam |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2374908A1 (fr) * | 1976-12-21 | 1978-07-21 | Theranol Lab | Medicament constitue par l'association optimale d'une substance vagomimetique, le salicylate d'amine-oxyde d'eserine, et d'une substance potentialisant la secretion gastrique, le chlorhydrate d'acide glutamique |
IT1199076B (it) * | 1984-03-01 | 1988-12-30 | Consiglio Nazionale Ricerche | Derivati della fisostigmina con proprieta'di inibizione della aceticolinesterasi e relativo procedimento di produzione |
IT1225462B (it) * | 1987-04-03 | 1990-11-14 | Mediolanum Farmaceutici Srl | Sali organici di derivati della fisostigmina |
-
1991
- 1991-08-09 IT ITMI912237A patent/IT1251166B/it active IP Right Grant
-
1992
- 1992-08-04 US US08/193,154 patent/US5538968A/en not_active Expired - Fee Related
- 1992-08-04 WO PCT/EP1992/001762 patent/WO1993003041A1/en active IP Right Grant
- 1992-08-04 AU AU23876/92A patent/AU659865B2/en not_active Ceased
- 1992-08-04 DE DE69218949T patent/DE69218949T2/de not_active Expired - Fee Related
- 1992-08-04 JP JP50327893A patent/JP3172185B2/ja not_active Expired - Fee Related
- 1992-08-04 CA CA002115250A patent/CA2115250A1/en not_active Abandoned
- 1992-08-04 ES ES92916772T patent/ES2101858T3/es not_active Expired - Lifetime
- 1992-08-04 AT AT92916772T patent/ATE151426T1/de not_active IP Right Cessation
- 1992-08-04 KR KR1019940700410A patent/KR100225927B1/ko not_active IP Right Cessation
- 1992-08-04 EP EP92916772A patent/EP0599890B1/en not_active Expired - Lifetime
- 1992-08-04 DK DK92916772.4T patent/DK0599890T3/da active
- 1992-08-04 HU HU9400353A patent/HU222774B1/hu not_active IP Right Cessation
- 1992-08-04 CZ CZ94262A patent/CZ281018B6/cs not_active IP Right Cessation
- 1992-08-06 ZA ZA925903A patent/ZA925903B/xx unknown
- 1992-08-06 NZ NZ243869A patent/NZ243869A/en unknown
-
1994
- 1994-02-08 NO NO940415A patent/NO303175B1/no unknown
- 1994-02-08 FI FI940573A patent/FI107532B/fi active
-
1997
- 1997-06-19 GR GR970401476T patent/GR3023838T3/el unknown
-
1998
- 1998-06-23 HK HK98106098A patent/HK1006714A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
FI107532B (fi) | 2001-08-31 |
NO940415D0 (no) | 1994-02-08 |
HU222774B1 (hu) | 2003-10-28 |
EP0599890A1 (en) | 1994-06-08 |
NO303175B1 (no) | 1998-06-08 |
HUT70414A (en) | 1995-10-30 |
KR100225927B1 (ko) | 1999-10-15 |
GR3023838T3 (en) | 1997-09-30 |
HK1006714A1 (en) | 1999-03-12 |
DE69218949T2 (de) | 1997-09-18 |
AU659865B2 (en) | 1995-06-01 |
ITMI912237A1 (it) | 1993-02-10 |
FI940573A0 (fi) | 1994-02-08 |
DK0599890T3 (da) | 1997-10-20 |
ES2101858T3 (es) | 1997-07-16 |
ZA925903B (en) | 1993-04-28 |
JP3172185B2 (ja) | 2001-06-04 |
CA2115250A1 (en) | 1993-02-18 |
WO1993003041A1 (en) | 1993-02-18 |
CZ26294A3 (en) | 1994-07-13 |
NO940415L (no) | 1994-04-06 |
NZ243869A (en) | 1994-03-25 |
HU9400353D0 (en) | 1994-06-28 |
AU2387692A (en) | 1993-03-02 |
CZ281018B6 (cs) | 1996-05-15 |
EP0599890B1 (en) | 1997-04-09 |
ATE151426T1 (de) | 1997-04-15 |
JPH06509572A (ja) | 1994-10-27 |
US5538968A (en) | 1996-07-23 |
DE69218949D1 (de) | 1997-05-15 |
FI940573A (fi) | 1994-03-28 |
IT1251166B (it) | 1995-05-04 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ITMI912237A0 (it) | Derivati di geneserina loro preparazione e composizioni farmaceutiche che li contengono | |
EE03108B1 (et) | Farmatseutiline kompositsioon | |
FI981777A (fi) | Farmaseuttinen ainekoostumus | |
IT8848714A0 (it) | Derivati di adenosina, composizioni farmaceutiche che li contengono erelativo procedimento di preparazione ed appplicazione | |
DE4291156T1 (de) | Verbesserte pharmazeutische Zusammensetzungen | |
ITMI910404A0 (it) | Derivati poli-4-aminopirrol-2-carbossiamidici,processi di preparazione e composizioni farmaceutiche che li contengono | |
BR9200058A (pt) | Composto e composicao farmaceutica | |
ITRM910952A0 (it) | Composizioni farmaceutiche contenenti gonadotropine | |
MX9200622A (es) | Composicion farmaceutica | |
IT1224226B (it) | Derivati benzofuranici procedimento per la loro preparazione e composizioni farmaceutiche e cosmetiche che li comprendono | |
ITMI912745A0 (it) | Derivati 5h-benzodiazepinici, composizioni farmaceutiche che li contengono e procedimento per la loro preparazione. | |
KR900012897A (ko) | 구아니딘 유도체 및 이를 함유하는 약제학적 조성물 | |
IT9022154A0 (it) | Derivati poliaminopirrolcarbossiamidici, processi di preparazione e composizioni farmaceutiche che li contengono | |
ITMI910846A1 (it) | Derivati di flavoni, procedimento per la loro preparazione e composizioni farmaceutiche che li contengono | |
IT9021305A0 (it) | Derivati aminopropanolici, procedimenti per la loro preparazione e composizioni farmaceutiche che li contengono | |
IT8948610A0 (it) | Derivati ciclici e loro metaboliti, loro preparazione e composizioni farmaceutiche che li contengono | |
IT1200079B (it) | Derivati della naftossazina, loro preparazione, loro applicazione come medicamenti e composizioni farmaceutiche che li contengono | |
ITFI920134A1 (it) | Derivati 7-neopentil xantinici, loro preparazione e composizioni farmaceutiche che li contengono | |
IT8847912A0 (it) | Derivati di forskolina, loro procedimento ed intermedi di preparazione, loro applicazione in qualita'di medicamenti e composizioni farmaceutiche che li contengono | |
IT9021880A0 (it) | Nuovi derivati di corticosteroidi, procedimento per la loro preparazione e composizioni farmaceutiche che li contengono | |
IT1257276B (it) | Derivati tienopirimidinonacrilici, loro preparazione e composizioni farmaceutiche che li contengono | |
IT1216120B (it) | Derivati n_cicloalchilaminoetilbenzamidici, loro preparazione e composizioni farmaceutiche che li contengono. | |
IT8823183A0 (it) | Derivati diossazocinici, loro preparazione e composizioni che li contengono | |
IT9019133A0 (it) | Acido 3-l-(5-tioxo-l-prolil)tiazolidin-4-carbossilico e derivati, loro preparazione e composizioni farmaceutiche che li contengono | |
IT9048494A0 (it) | Ftalidilidene derivati della carnitina e di alcanoil carnitine e composizioni farmaceutiche che li contengono. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
0001 | Granted | ||
TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19960826 |