HK1006714A1 - Geneserine derivatives as cholinesterase inhibitors - Google Patents

Geneserine derivatives as cholinesterase inhibitors

Info

Publication number
HK1006714A1
HK1006714A1 HK98106098A HK98106098A HK1006714A1 HK 1006714 A1 HK1006714 A1 HK 1006714A1 HK 98106098 A HK98106098 A HK 98106098A HK 98106098 A HK98106098 A HK 98106098A HK 1006714 A1 HK1006714 A1 HK 1006714A1
Authority
HK
Hong Kong
Prior art keywords
pct
group
sec
geneserine
derivatives
Prior art date
Application number
HK98106098A
Other languages
English (en)
Inventor
Paolo Chiesi
Maurizio Del Canale
Vittorino Servadio
Eleonora Ghidini
Original Assignee
Chiesi Farma Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiesi Farma Spa filed Critical Chiesi Farma Spa
Publication of HK1006714A1 publication Critical patent/HK1006714A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Neurology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pyrane Compounds (AREA)
  • Saccharide Compounds (AREA)
HK98106098A 1991-08-09 1998-06-23 Geneserine derivatives as cholinesterase inhibitors HK1006714A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITMI912237A IT1251166B (it) 1991-08-09 1991-08-09 Derivati di geneserina,loro preparazione e composizioni farmaceutiche che li contengono
PCT/EP1992/001762 WO1993003041A1 (en) 1991-08-09 1992-08-04 Geneserine derivatives as cholinesterase inhibitors

Publications (1)

Publication Number Publication Date
HK1006714A1 true HK1006714A1 (en) 1999-03-12

Family

ID=11360556

Family Applications (1)

Application Number Title Priority Date Filing Date
HK98106098A HK1006714A1 (en) 1991-08-09 1998-06-23 Geneserine derivatives as cholinesterase inhibitors

Country Status (20)

Country Link
US (1) US5538968A (de)
EP (1) EP0599890B1 (de)
JP (1) JP3172185B2 (de)
KR (1) KR100225927B1 (de)
AT (1) ATE151426T1 (de)
AU (1) AU659865B2 (de)
CA (1) CA2115250A1 (de)
CZ (1) CZ281018B6 (de)
DE (1) DE69218949T2 (de)
DK (1) DK0599890T3 (de)
ES (1) ES2101858T3 (de)
FI (1) FI107532B (de)
GR (1) GR3023838T3 (de)
HK (1) HK1006714A1 (de)
HU (1) HU222774B1 (de)
IT (1) IT1251166B (de)
NO (1) NO303175B1 (de)
NZ (1) NZ243869A (de)
WO (1) WO1993003041A1 (de)
ZA (1) ZA925903B (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1023297A1 (de) * 1997-10-10 2000-08-02 CHIESI FARMACEUTICI S.p.A. Verfahren zur herstellung von aminocarbonyl-derivaten von geneserolin mit selektiver anticholinesterase-aktivität im gehirn
DE19853487A1 (de) * 1998-11-19 2000-05-25 Fumapharm Ag Muri Verwendung von Dialkylfumaraten
DE10000577A1 (de) * 2000-01-10 2001-07-26 Fumapharm Ag Muri Verwendung von Fumarsäurederivaten zur Behandlung mitochondrialer Krankheiten
CZ304198B6 (cs) * 2001-01-12 2013-12-27 Fumapharm Ag Amidy kyseliny fumarové
DE10101307A1 (de) * 2001-01-12 2002-08-01 Fumapharm Ag Muri Fumarsäurederivate als NF-kappaB-Inhibitor
PL1663197T3 (pl) 2003-09-09 2008-09-30 Biogen Idec Int Gmbh Zastosowanie pochodnych kwasu fumarowego do leczenia niewydolności serca oraz astmy
WO2005042475A2 (en) * 2003-10-21 2005-05-12 Sention, Inc. Carbamoyl esters that inhibit cholinesterase and release pharmacologically active agents
JP2010518010A (ja) * 2007-02-02 2010-05-27 コルシド・ファーマシューティカルズ・インコーポレイテッド コリンエステラーゼを阻害する化合物
LT2653873T (lt) 2007-02-08 2022-10-10 Biogen Ma Inc. Kompozicijos ir naudojimas, skirti išsėtinei sklerozei gydyti
ES2599227T3 (es) * 2007-02-08 2017-01-31 Biogen Ma Inc. Neuroprotección en enfermedades desmielinizantes
US20090048229A1 (en) * 2007-07-18 2009-02-19 Rupniak Nadia M J Methods for promoting wakefulness
US8593728B2 (en) * 2009-02-19 2013-11-26 Toyota Motor Engineering & Manufacturing North America, Inc. Multilayer photonic structures
WO2011100373A1 (en) 2010-02-09 2011-08-18 The Johns Hopkins University Methods and compositions for improving cognitive function
US10154988B2 (en) 2012-11-14 2018-12-18 The Johns Hopkins University Methods and compositions for treating schizophrenia
NZ631337A (en) 2013-03-14 2017-01-27 Alkermes Pharma Ireland Ltd Prodrugs of fumarates and their use in treating various diseases
US8669281B1 (en) 2013-03-14 2014-03-11 Alkermes Pharma Ireland Limited Prodrugs of fumarates and their use in treating various diseases
EP3827820A1 (de) 2013-03-15 2021-06-02 The Johns Hopkins University Brivaracetam zur verbesserung der kognitiven funktion
JP6433482B2 (ja) 2013-03-15 2018-12-05 エージンバイオ， インコーポレイテッド 認知機能を改善するための方法および組成物
AU2015218587B2 (en) 2014-02-24 2017-04-27 Alkermes Pharma Ireland Limited Sulfonamide and sulfinamide prodrugs of fumarates and their use in treating various diseases
WO2016191288A1 (en) 2015-05-22 2016-12-01 Agenebio, Inc. Extended release pharmaceutical compositions of levetiracetam

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2374908A1 (fr) * 1976-12-21 1978-07-21 Theranol Lab Medicament constitue par l'association optimale d'une substance vagomimetique, le salicylate d'amine-oxyde d'eserine, et d'une substance potentialisant la secretion gastrique, le chlorhydrate d'acide glutamique
IT1199076B (it) * 1984-03-01 1988-12-30 Consiglio Nazionale Ricerche Derivati della fisostigmina con proprieta'di inibizione della aceticolinesterasi e relativo procedimento di produzione
IT1225462B (it) * 1987-04-03 1990-11-14 Mediolanum Farmaceutici Srl Sali organici di derivati della fisostigmina

Also Published As

Publication number Publication date
KR100225927B1 (ko) 1999-10-15
FI940573A0 (fi) 1994-02-08
DE69218949D1 (de) 1997-05-15
DK0599890T3 (da) 1997-10-20
DE69218949T2 (de) 1997-09-18
NO940415L (no) 1994-04-06
JPH06509572A (ja) 1994-10-27
US5538968A (en) 1996-07-23
NZ243869A (en) 1994-03-25
ZA925903B (en) 1993-04-28
EP0599890B1 (de) 1997-04-09
EP0599890A1 (de) 1994-06-08
HU9400353D0 (en) 1994-06-28
IT1251166B (it) 1995-05-04
FI107532B (fi) 2001-08-31
CA2115250A1 (en) 1993-02-18
HUT70414A (en) 1995-10-30
NO940415D0 (no) 1994-02-08
FI940573A (fi) 1994-03-28
ITMI912237A1 (it) 1993-02-10
ITMI912237A0 (it) 1991-08-09
ES2101858T3 (es) 1997-07-16
GR3023838T3 (en) 1997-09-30
AU2387692A (en) 1993-03-02
HU222774B1 (hu) 2003-10-28
NO303175B1 (no) 1998-06-08
JP3172185B2 (ja) 2001-06-04
CZ26294A3 (en) 1994-07-13
ATE151426T1 (de) 1997-04-15
AU659865B2 (en) 1995-06-01
CZ281018B6 (cs) 1996-05-15
WO1993003041A1 (en) 1993-02-18

Similar Documents

Publication Publication Date Title
HU9400353D0 (en) Geneserine derivatives as cholinesterase inhibitors
FI943948A (fi) Heterosykliset hiilihappojohdannaiset
HU9600278D0 (en) Remedy for nervous diseases
HK1004481A1 (en) Depsipeptide derivative, production thereof and use thereof
DK616388A (da) Quinolincarboxylsyre-derivater og fysiologisk acceptable salte deraf med antibakteriel virkning
ATE184483T1 (de) Spirooxathiolan-quinuclidin-derivat zur behandlung des sjögren-syndroms
DE60002558D1 (de) Derivate der Phosphonsäure zur Inhibierung von Carboxypeptidase B
AU7777491A (en) Cyclic hydroxamic acids and their use
ES2043820T3 (es) Nuevas 1-1 alkil-1-sulfonil-2-alkoxicarbonilsulfenilhidrazinas que tienen actividad antineoplastica.
ATE43140T1 (de) Derivate von enzym-hemmender griseolsaeure und deren verwendung.
MA19434A1 (fr) Procede de preparation de nouvelles imidazo/i, 2-a/quinoleines et de leurs sels
EP0338937A3 (en) 1-û3-(4-hydroxy-phenyl)-1-hydoxy-1-propyl¨-2-(amino-alkyleneoxy)-benzene derivatives, process for their preparation and their therapeutical use
ATE92468T1 (de) Zimtsaeureamid-derivate.
ATE144900T1 (de) Verwendung von xanthinderivaten gegen magengeschwüre
CA2267471A1 (en) Bisthiadiazole derivatives and salts thereof, disease controlling agents for agricultural and horticultural use, and method for the use thereof
BR9306170A (pt) Amidas de ácido isoxazolcarboxílico processo para sua produç o composiç es herbicidas e processo para o comtrole do crescimento vegetal indesejado
WO1999059982A3 (de) Bisoximetherderivate, zwischenprodukte und verwendung zur bekämpfung von schadpilzen und tierischen schädlingen

Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)