ATE239711T1 - Neue allythiopyridazinderivate und verfahren zu ihrer herstellung - Google Patents

Neue allythiopyridazinderivate und verfahren zu ihrer herstellung

Info

Publication number
ATE239711T1
ATE239711T1 AT98961671T AT98961671T ATE239711T1 AT E239711 T1 ATE239711 T1 AT E239711T1 AT 98961671 T AT98961671 T AT 98961671T AT 98961671 T AT98961671 T AT 98961671T AT E239711 T1 ATE239711 T1 AT E239711T1
Authority
AT
Austria
Prior art keywords
lower alkyl
allythiopyridazine
derivatives
new
production
Prior art date
Application number
AT98961671T
Other languages
English (en)
Inventor
Soon Kyoung Kwon
Sang Geon Kim
Young Nam Park
Mi Kyung Kim
Sung Hee Choi
Hea Soon Shin
Original Assignee
Seoul Pharm Co Ltd
Soon Kyoung Kwon
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Seoul Pharm Co Ltd, Soon Kyoung Kwon filed Critical Seoul Pharm Co Ltd
Application granted granted Critical
Publication of ATE239711T1 publication Critical patent/ATE239711T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/18—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Retarders (AREA)
  • General Details Of Gearings (AREA)
AT98961671T 1998-01-16 1998-12-28 Neue allythiopyridazinderivate und verfahren zu ihrer herstellung ATE239711T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1019980001153A KR100261139B1 (ko) 1998-01-16 1998-01-16 신규한 알릴티오피리다진 유도체 및 그의 제조방법
PCT/KR1998/000473 WO1999036407A1 (en) 1998-01-16 1998-12-28 Novel allylthiopyridazine derivatives and process for preparing the same

Publications (1)

Publication Number Publication Date
ATE239711T1 true ATE239711T1 (de) 2003-05-15

Family

ID=19531606

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98961671T ATE239711T1 (de) 1998-01-16 1998-12-28 Neue allythiopyridazinderivate und verfahren zu ihrer herstellung

Country Status (9)

Country Link
US (1) US5942511A (de)
EP (1) EP1058681B1 (de)
JP (1) JP3417926B2 (de)
KR (1) KR100261139B1 (de)
CN (1) CN1147477C (de)
AT (1) ATE239711T1 (de)
CA (1) CA2317673C (de)
DE (1) DE69814473T9 (de)
WO (1) WO1999036407A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7078045B2 (en) * 2000-03-02 2006-07-18 Sang-Geon Kim Pharmaceutical composition for treatment and prevention of liver fibrosis and cirrhosis
CA2404915A1 (en) * 2000-04-07 2001-10-18 Sang Geon Kim Prophylactic and therapeutic use of oltipraz as an antifibrotic and anticirrhotic agent in the liver and pharmaceutical composition containing oltipraz
KR20030067935A (ko) * 2002-02-09 2003-08-19 김상건 올티프라즈를 포함하는 간경화(간경변증) 치료를 위한 간 조직 재생용 제약 조성물
KR100446103B1 (ko) * 2002-04-19 2004-08-30 주식회사 서울제약 알릴티오피리다진 유도체를 함유하는 간암 예방 및 치료용의약 조성물
KR100823891B1 (ko) * 2004-08-31 2008-04-21 주식회사파마킹 항암활성을 갖는 알릴티오피리다진 유도체
JO2769B1 (en) 2005-10-26 2014-03-15 جانسين فارماسوتيكا ان. في Rapid decomposition of physiologically antagonistic agents of the 2-dopamine receptor
WO2007058394A1 (en) * 2005-11-16 2007-05-24 Seoul Pharm. Co., Ltd. Medicinal composition comprising 3-alkoxy-6-allylthiopyridazines for prevention or treatment of cancer of the pancreas
JO2642B1 (en) 2006-12-08 2012-06-17 جانسين فارماسوتيكا ان. في Dopamine 2 receptor antagonists are rapidly hydrolyzed
JO2849B1 (en) 2007-02-13 2015-03-15 جانسين فارماسوتيكا ان. في Dopamine 2 receptor antagonists are rapidly hydrolyzed
RS52518B (en) 2007-04-23 2013-04-30 Janssen Pharmaceutica N.V. 4-ALCOXYPYRIDASINE DERIVATIVES AS A FAST DISSOCATING DOPAMINE 2 RECEPTOR ANTAGONISTS
CN101663299A (zh) 2007-04-23 2010-03-03 詹森药业有限公司 作为快速解离性多巴胺2受体拮抗剂的噻(二)唑类化合物
WO2010000456A1 (en) 2008-07-03 2010-01-07 Janssen Pharmaceutica Nv Substituted 6- (1-piperazinyl) -pyridazines as 5-ht6 receptor antagonists
HUE033768T2 (en) 2008-07-31 2017-12-28 Janssen Pharmaceutica Nv Piperazin-1-yl-trifluoromethyl-substituted pyridines as rapidly dissociating dopamine-2 receptor antagonists

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2627075A1 (de) * 1976-06-16 1977-12-29 Bayer Ag Substituierte pyridazinyl(thiono)(thiol)-phosphor(phosphon)-saeureesterderivate, verfahren zu ihrer herstellung und ihre verwendung als insektizide und akarizide
US5550134A (en) * 1995-05-10 1996-08-27 Eli Lilly And Company Methods for inhibiting bone loss

Also Published As

Publication number Publication date
EP1058681A1 (de) 2000-12-13
DE69814473D1 (de) 2003-06-12
WO1999036407A1 (en) 1999-07-22
KR19990065727A (ko) 1999-08-05
JP2002509138A (ja) 2002-03-26
CN1147477C (zh) 2004-04-28
JP3417926B2 (ja) 2003-06-16
DE69814473T9 (de) 2005-02-03
CA2317673C (en) 2004-09-21
CN1285825A (zh) 2001-02-28
CA2317673A1 (en) 1999-07-22
US5942511A (en) 1999-08-24
KR100261139B1 (ko) 2000-08-01
EP1058681B1 (de) 2003-05-07
DE69814473T2 (de) 2004-04-08

Similar Documents

Publication Publication Date Title
HUP0105414A2 (hu) Pirrolo-izokinolin-, azepino- és diazepino-indol-származékok, alkalmazásuk és az ezeket tartalmazó gyógyszerkészítmények
ES2121441T3 (es) Nuevos derivados de 3,5 -dioxo - (2h,4h) - 1,2,4 - triazina,su preparacion y aplicacion como farmaco
BR0014137A (pt) Composto, método para inibir a aurora 2 quinase em um animal de sangue quente, uso de um composto, e, composição farmacêutica
ATE25974T1 (de) Acyl-substituierte derivate von 1,2,3,4tetrahydroisochinolin-3-carboxysaeuren, ihre salze, diese enthaltende arzneimittel und verfahren zu ihrer herstellung.
RU2088589C1 (en) Derivatives of 17 beta-substituted-4-aza-5-5 alpha-androstane-3-ones, methods of synthesis of compounds, pharmaceutical composition, compound 4
ES2044836T3 (es) Derivado de la piperidina, su utilizacion y compuesto farmaceutico que lo contiene.
SE0104334D0 (sv) Therapeutic agents
BR9405988A (pt) Derivados da dialotriazolpirimidina como fungicidas
ATE235476T1 (de) Thiazolidindione derivate, ihre herstellung und verwendung
ATE239711T1 (de) Neue allythiopyridazinderivate und verfahren zu ihrer herstellung
DE2960820D1 (en) Carbostyrile derivatives, processes for their preparation and pharmaceutical compositions containing them
ATE2622T1 (de) 2-niedrigalkyl-7-substituierte-2 oder 3-cephem-4- carbonsaeuren, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusammensetzungen.
ES8704917A1 (es) Procedimiento para prepararar derivados de 1-piperazinacarboximida.
IL112432A0 (en) Fatty acid derivatives, methods for the preparation thereof and pharmaceutical compositions containing the same
DE69330601D1 (de) Serotoninergische ergolin derivate
HU895391D0 (en) Process for the preparation of novelnitroxy-alkyl-amine derivatives and pharmaceutical compositions containing said compounds
ES8203870A1 (es) Procedimiento para preparar difenilbutil-1-acilpiperazinas
ATE127465T1 (de) Isoindolinon-derivat, seine herstellung und dieses enthaltende pharmazeutische zusammen setzungen.
HUP9903526A2 (hu) Pirimidinszármazékok és az ezeket tartalmazó gyógyszerkészítmények
ES2016017A6 (es) Procedimiento para preparar derivados de acido 1,1-dioxocefem-4-carbotiolico.
AU655869B2 (en) An amphoteric tricyclic compound
ATE18761T1 (de) Carbamoyloxybenzhydrol-derivate, ihre herstellung und ihre pharmazeutische zusammensetzungen.
AU5125798A (en) Novel n-benzenesulphonyl-l-proline derivatives, method for preparing and therapeutic use
EA200600022A1 (ru) Применение производных бицикло [2.2.1] гептана для приготовления нейропротекторных фармацевтических композиций
SG146685A1 (en) Dihydroporphine derivatives, processes for their preparation, and pharmaceutical compositions containing them

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties