ATE2622T1 - 2-niedrigalkyl-7-substituierte-2 oder 3-cephem-4- carbonsaeuren, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusammensetzungen. - Google Patents

2-niedrigalkyl-7-substituierte-2 oder 3-cephem-4- carbonsaeuren, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusammensetzungen.

Info

Publication number
ATE2622T1
ATE2622T1 AT79102989T AT79102989T ATE2622T1 AT E2622 T1 ATE2622 T1 AT E2622T1 AT 79102989 T AT79102989 T AT 79102989T AT 79102989 T AT79102989 T AT 79102989T AT E2622 T1 ATE2622 T1 AT E2622T1
Authority
AT
Austria
Prior art keywords
sup
preparation
galkyl
cephem
substituted
Prior art date
Application number
AT79102989T
Other languages
English (en)
Inventor
Takashi Kamiya
Takao Takaya
Original Assignee
Fujisawa Pharmaceutical Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujisawa Pharmaceutical Co., Ltd. filed Critical Fujisawa Pharmaceutical Co., Ltd.
Application granted granted Critical
Publication of ATE2622T1 publication Critical patent/ATE2622T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT79102989T 1978-08-17 1979-08-16 2-niedrigalkyl-7-substituierte-2 oder 3-cephem-4- carbonsaeuren, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusammensetzungen. ATE2622T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB7833766 1978-08-17
EP79102989A EP0008442B1 (de) 1978-08-17 1979-08-16 2-Niedrigalkyl-7-substituierte-2 oder 3-cephem-4-carbonsäuren, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Zusammensetzungen

Publications (1)

Publication Number Publication Date
ATE2622T1 true ATE2622T1 (de) 1983-03-15

Family

ID=10499129

Family Applications (1)

Application Number Title Priority Date Filing Date
AT79102989T ATE2622T1 (de) 1978-08-17 1979-08-16 2-niedrigalkyl-7-substituierte-2 oder 3-cephem-4- carbonsaeuren, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusammensetzungen.

Country Status (5)

Country Link
US (1) US4305937A (de)
EP (1) EP0008442B1 (de)
JP (1) JPS5536493A (de)
AT (1) ATE2622T1 (de)
DE (1) DE2964903D1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4372952A (en) * 1978-07-31 1983-02-08 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds
FR2461713A1 (fr) 1979-07-19 1981-02-06 Roussel Uclaf Nouvelles alcoyloximes substituees derivees de l'acide 7-(2-amino 4-thiazolyl) acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
US4409214A (en) * 1979-11-19 1983-10-11 Fujisawa Pharmaceutical, Co., Ltd. 7-Acylamino-3-vinylcephalosporanic acid derivatives and processes for the preparation thereof
US4510300A (en) * 1982-04-08 1985-04-09 E. I. Du Pont De Nemours And Company Perfluorocarbon copolymer films
US4510301A (en) * 1982-06-01 1985-04-09 E. I. Du Pont De Nemours And Company Fluorocarbon copolymer films
JPS59212226A (ja) * 1983-05-17 1984-12-01 Furukawa Electric Co Ltd:The 絶縁用多層巻プラスチツクチユ−ブの製造方法
AT381944B (de) * 1984-04-10 1986-12-10 Biochemie Gmbh Verfahren zur herstellung von cephalosporinantibiotika
JP6151257B2 (ja) 2011-09-09 2017-06-21 メルク・シャープ・アンド・ドーム・コーポレーションＭｅｒｃｋ Ｓｈａｒｐ ＆ Ｄｏｈｍｅ Ｃｏｒｐ． 肺内感染症の治療方法
US8809314B1 (en) 2012-09-07 2014-08-19 Cubist Pharmacueticals, Inc. Cephalosporin compound
US8476425B1 (en) 2012-09-27 2013-07-02 Cubist Pharmaceuticals, Inc. Tazobactam arginine compositions
EP2777705A1 (de) 2013-03-15 2014-09-17 Cubist Pharmaceuticals, Inc. Antibiotische Ceftolozanzusammensetzungen
US20140274993A1 (en) 2013-03-15 2014-09-18 Cubist Pharmaceuticals, Inc. Ceftolozane-tazobactam pharmaceutical compositions
US9872906B2 (en) 2013-03-15 2018-01-23 Merck Sharp & Dohme Corp. Ceftolozane antibiotic compositions
US10376496B2 (en) 2013-09-09 2019-08-13 Merck, Sharp & Dohme Corp. Treating infections with ceftolozane/tazobactam in subjects having impaired renal function
US20150094293A1 (en) 2013-09-27 2015-04-02 Calixa Therapeutics, Inc. Solid forms of ceftolozane

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3719672A (en) * 1968-12-11 1973-03-06 Ciba Geigy Corp 4-substituted methylene-7-amino-8-oxo-5-thia-1-aza-bicyclo(4,2,0 oct-2-ene-2-carboxylic acids
US3660396A (en) * 1970-03-04 1972-05-02 Lilly Co Eli Cephalosporin intermediates and process therefor
CH563396A5 (de) * 1970-06-05 1975-06-30 Ciba Geigy Ag
US4024133A (en) * 1971-05-14 1977-05-17 Glaxo Laboratories Limited 7β-[2-Etherified oximino-2-(thienyl-,furyl- or pyridylacetamido)]cephalosporins
US4113940A (en) * 1973-03-15 1978-09-12 Fujisawa Pharmaceutical Co., Ltd. 7-amino 2-lower alkyl-2 or 3-cephem-4-carboxylic acid derivatives and processes for preparation thereof
GB1496351A (en) 1974-01-02 1977-12-30 Glaxo Lab Ltd 2-substituted ceph-3-em-4-carboxylic acid derivatives
US4191762A (en) * 1974-03-14 1980-03-04 Fujisawa Pharmaceutical Co., Ltd. 2-Lower alkyl-7-substituted amino-2 or 3-cephem-4-carboxylic acid compounds
DK154939C (da) * 1974-12-19 1989-06-12 Takeda Chemical Industries Ltd Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf
DE2760123C2 (de) * 1976-01-23 1986-04-30 Roussel-Uclaf, Paris 7-Aminothiazolyl-syn-oxyiminoacetamidocephalosporansäuren, ihre Herstellung und sie enthaltende pharmazeutische Zusammensetzungen
US4152433A (en) * 1976-03-12 1979-05-01 Fujisawa Pharmaceutical Co., Ltd. 2-Lower alkyl-7-substituted-2 or 3-cephem-4-carboxylic acid compounds and pharmaceutical compositions
US4166115A (en) * 1976-04-12 1979-08-28 Fujisawa Pharmaceutical Co., Ltd. Syn 7-oxoimino substituted derivatives of cephalosporanic acid
FI771866A (de) * 1976-06-28 1977-12-29 Fujisawa Pharmaceutical Co
PH17188A (en) * 1977-03-14 1984-06-14 Fujisawa Pharmaceutical Co New cephem and cepham compounds and their pharmaceutical compositions and method of use

Also Published As

Publication number Publication date
JPH0121151B2 (de) 1989-04-19
US4305937A (en) 1981-12-15
JPS5536493A (en) 1980-03-14
EP0008442A2 (de) 1980-03-05
DE2964903D1 (en) 1983-03-31
EP0008442B1 (de) 1983-02-23
EP0008442A3 (en) 1980-05-28

Similar Documents

Publication Publication Date Title
ZA875261B (en) Aromatic,bicyclic derivatives,process for their preparation and their medical,veterinary and cosmetic use
ATE2622T1 (de) 2-niedrigalkyl-7-substituierte-2 oder 3-cephem-4- carbonsaeuren, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusammensetzungen.
ES485188A1 (es) Procedimiento para preparar 1-piperazina-carboxamidas y car-botiamidas
FR2387941A1 (fr) Homologue de la somatostatine, ses intermediaires de preparation, et son utilisation comme medicament
SE8601103D0 (sv) Neue, schwefelhaltige 5-substituierte benzimidazol-derivate und verfahren zu ihrer herstellung
KR890008155A (ko) 신규인 유도체, 그 제조방법 및 의약에서의 사용
ATE19878T1 (de) Benzimidazol-derivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen.
ATE50575T1 (de) 2-oximino-2-aminothiazolylessigsaeurederivate und verfahren zu ihrer herstellung.
KR900014406A (ko) 세펨 화합물 및 이의 제조방법
DE2967356D1 (en) Cephalosporin derivatives, process for their preparation and pharmaceutical compositions containing them
DE69814473D1 (de) Neue allythiopyridazinderivate und verfahren zu ihrer herstellung
ES427079A1 (es) Un metodo de preparacion de fenotiazidas sustituidas por fluor en la posicion 7.
DK601683D0 (da) Dialkylaminoalkoxybenzylalkoholderivater
ES475533A1 (es) Un metodo para la preparacion de formas racemicas y optica- mente activas de 2-(4-difenilil)-n-(dimetilamino-alquil)pro-pionamida
DE3164314D1 (en) Azolylalkyl derivatives, process for their preparation and their use as fungicides
EP0030023A3 (de) Heterocyclische Verbindung und ihre Herstellung, sie enthaltende pharmazeutische Zusammensetzungen und die Verwendung der Verbindung und der Zusammensetzung in der Medizin
ES461785A1 (es) Un metodo para la preparacion de un ester de acido behenico.
JPS5673046A (en) Decaprenylamine derivative
AU530930B2 (en) Pharmaceutical compositions and method of treating heart disease
FR2455598A1 (fr) Nouveaux derives 5- (2- ((2,3-dihydro-1,4-benzodioxanne-2-ylmethyl)- amino)-1- hydroxyethyl)-2-hydroxybenzoiques, utiles notamment comme agents bloquants des recepteurs adrenergiques a et b, et leur procede de preparation
IL64839A (en) N-arylmethyl-4-(methylanilino)-5-sulfamoyl-anthranilic acids,a process for their preparation and pharmaceutical compositions containing them
ES8801291A1 (es) Un procedimiento para la preparacion de nuevos derivados de beta-lactama.
KR910002789A (ko) 아크릴산염, 이것의 제조방법, 이것을 함유한 제약조성물 및 의약에서 이것을 사용하는 방법
JPS5673047A (en) Decaprenylamine derivative
ES8105724A1 (es) Procedimiento para la preparacion de nuevas ureas sustitui- das con radicales basicos

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee