ATE50575T1 - 2-oximino-2-aminothiazolylessigsaeurederivate und verfahren zu ihrer herstellung. - Google Patents
2-oximino-2-aminothiazolylessigsaeurederivate und verfahren zu ihrer herstellung.Info
- Publication number
- ATE50575T1 ATE50575T1 AT85116546T AT85116546T ATE50575T1 AT E50575 T1 ATE50575 T1 AT E50575T1 AT 85116546 T AT85116546 T AT 85116546T AT 85116546 T AT85116546 T AT 85116546T AT E50575 T1 ATE50575 T1 AT E50575T1
- Authority
- AT
- Austria
- Prior art keywords
- sup
- group
- suitable substituent
- oximino
- production
- Prior art date
Links
- 125000001424 substituent group Chemical group 0.000 abstract 3
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- -1 pyridinio Chemical class 0.000 abstract 2
- 125000004423 acyloxy group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 239000004615 ingredient Substances 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229920006395 saturated elastomer Polymers 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
- 125000004434 sulfur atom Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D257/04—Five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8028933 | 1980-09-08 | ||
| EP85116546A EP0184227B1 (de) | 1980-09-08 | 1981-09-03 | 2-Oximino-2-aminothiazolylessigsäurederivate und Verfahren zu ihrer Herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE50575T1 true ATE50575T1 (de) | 1990-03-15 |
Family
ID=10515925
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT85116546T ATE50575T1 (de) | 1980-09-08 | 1981-09-03 | 2-oximino-2-aminothiazolylessigsaeurederivate und verfahren zu ihrer herstellung. |
| AT81106870T ATE27956T1 (de) | 1980-09-08 | 1981-09-03 | Cephalosporinverbindungen und verfahren zu ihrer herstellung. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT81106870T ATE27956T1 (de) | 1980-09-08 | 1981-09-03 | Cephalosporinverbindungen und verfahren zu ihrer herstellung. |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US4416879A (de) |
| EP (2) | EP0047491B1 (de) |
| JP (2) | JPS5777689A (de) |
| AT (2) | ATE50575T1 (de) |
| DE (2) | DE3176274D1 (de) |
| ES (2) | ES8303423A1 (de) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4405617A (en) * | 1980-02-11 | 1983-09-20 | Fujisawa Pharmaceutical Co., Ltd. | 3-(Propynyltetrazol)thiomethyl-3-cephems |
| US4416879A (en) * | 1980-09-08 | 1983-11-22 | Fujisawa Pharmaceutical Co., Ltd. | Cephem compounds |
| IE55406B1 (en) * | 1982-08-07 | 1990-09-12 | Tanabe Seiyaku Co | Novel cephalosporin compounds and preparation thereof |
| JPS5946292A (ja) * | 1982-09-09 | 1984-03-15 | Otsuka Chem Co Ltd | ２−置換セフエム誘導体の製造法 |
| US4608373A (en) * | 1982-12-13 | 1986-08-26 | Yamanouchi Pharmaceutical Co., Ltd. | Cephem compounds |
| CA1267647A (en) * | 1984-12-27 | 1990-04-10 | Ryosuke Ushijima | Cephalosporin derivatives |
| US4814328A (en) * | 1986-03-19 | 1989-03-21 | Banyu Pharmaceutical Co., Ltd. | Cephalosporin derivatives, and antibacterial agents |
| US6559430B2 (en) | 2001-01-04 | 2003-05-06 | General Mills, Inc. | Foil edge control for microwave heating |
| JP6151257B2 (ja) | 2011-09-09 | 2017-06-21 | メルク・シャープ・アンド・ドーム・コーポレーションＭｅｒｃｋ Ｓｈａｒｐ ＆ Ｄｏｈｍｅ Ｃｏｒｐ． | 肺内感染症の治療方法 |
| US8809314B1 (en) | 2012-09-07 | 2014-08-19 | Cubist Pharmacueticals, Inc. | Cephalosporin compound |
| US8476425B1 (en) | 2012-09-27 | 2013-07-02 | Cubist Pharmaceuticals, Inc. | Tazobactam arginine compositions |
| US9872906B2 (en) | 2013-03-15 | 2018-01-23 | Merck Sharp & Dohme Corp. | Ceftolozane antibiotic compositions |
| US20140274993A1 (en) | 2013-03-15 | 2014-09-18 | Cubist Pharmaceuticals, Inc. | Ceftolozane-tazobactam pharmaceutical compositions |
| EP3100732A1 (de) | 2013-03-15 | 2016-12-07 | Merck Sharp & Dohme Corp. | Antibiotische ceftolozanzusammensetzungen |
| US10376496B2 (en) | 2013-09-09 | 2019-08-13 | Merck, Sharp & Dohme Corp. | Treating infections with ceftolozane/tazobactam in subjects having impaired renal function |
| US8906898B1 (en) | 2013-09-27 | 2014-12-09 | Calixa Therapeutics, Inc. | Solid forms of ceftolozane |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1399086A (en) * | 1971-05-14 | 1975-06-25 | Glaxo Lab Ltd | Cephalosporin compounds |
| DE2714880A1 (de) * | 1977-04-02 | 1978-10-26 | Hoechst Ag | Cephemderivate und verfahren zu ihrer herstellung |
| DE2716677C2 (de) * | 1977-04-15 | 1985-10-10 | Hoechst Ag, 6230 Frankfurt | Cephemderivate und Verfahren zu ihrer Herstellung |
| EP0059486B1 (de) * | 1978-07-17 | 1985-10-02 | Fujisawa Pharmaceutical Co., Ltd. | Ausgangsprodukte zur Herstellung von Cephalosporinen und Verfahren zu ihrer Herstellung |
| US4284631A (en) * | 1978-07-31 | 1981-08-18 | Fujisawa Pharmaceutical Co., Ltd. | 7-Substituted cephem compounds and pharmaceutical antibacterial compositions containing them |
| GB2028305A (en) * | 1978-08-03 | 1980-03-05 | Hoechst Ag | Cephem derivatives and processes for their manufacture |
| HU183006B (en) * | 1978-12-29 | 1984-04-28 | Fujisawa Pharmaceutical Co | Process for producing 7-substituted-3-cepheme- and cephame-4-carboxylic acid derivatives |
| US4416879A (en) * | 1980-09-08 | 1983-11-22 | Fujisawa Pharmaceutical Co., Ltd. | Cephem compounds |
-
1981
- 1981-08-27 US US06/296,860 patent/US4416879A/en not_active Expired - Fee Related
- 1981-09-03 AT AT85116546T patent/ATE50575T1/de active
- 1981-09-03 EP EP81106870A patent/EP0047491B1/de not_active Expired
- 1981-09-03 JP JP56139430A patent/JPS5777689A/ja active Granted
- 1981-09-03 DE DE8181106870T patent/DE3176274D1/de not_active Expired
- 1981-09-03 EP EP85116546A patent/EP0184227B1/de not_active Expired - Lifetime
- 1981-09-03 DE DE8585116546T patent/DE3177159D1/de not_active Expired - Fee Related
- 1981-09-03 AT AT81106870T patent/ATE27956T1/de not_active IP Right Cessation
- 1981-09-07 ES ES505257A patent/ES8303423A1/es not_active Expired
-
1982
- 1982-08-02 ES ES514654A patent/ES514654A0/es active Granted
-
1983
- 1983-08-16 US US06/523,594 patent/US4533738A/en not_active Expired - Lifetime
-
1987
- 1987-08-31 JP JP62218157A patent/JPS6393781A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| ES505257A0 (es) | 1983-02-01 |
| EP0184227A1 (de) | 1986-06-11 |
| US4416879A (en) | 1983-11-22 |
| DE3176274D1 (en) | 1987-07-30 |
| DE3177159D1 (de) | 1990-04-05 |
| JPS6393781A (ja) | 1988-04-25 |
| JPH0158191B2 (de) | 1989-12-11 |
| US4533738A (en) | 1985-08-06 |
| EP0047491B1 (de) | 1987-06-24 |
| EP0047491A3 (en) | 1983-03-16 |
| JPS5777689A (en) | 1982-05-15 |
| EP0184227B1 (de) | 1990-02-28 |
| ATE27956T1 (de) | 1987-07-15 |
| EP0047491A2 (de) | 1982-03-17 |
| JPH0327552B2 (de) | 1991-04-16 |
| ES8307825A1 (es) | 1983-07-01 |
| ES8303423A1 (es) | 1983-02-01 |
| ES514654A0 (es) | 1983-07-01 |
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