ZA919752B - Fluorine compounds - Google Patents

Fluorine compounds

Info

Publication number
ZA919752B
ZA919752B ZA919752A ZA919752A ZA919752B ZA 919752 B ZA919752 B ZA 919752B ZA 919752 A ZA919752 A ZA 919752A ZA 919752 A ZA919752 A ZA 919752A ZA 919752 B ZA919752 B ZA 919752B
Authority
ZA
South Africa
Prior art keywords
fluorine compounds
compounds
prepared
formula
image
Prior art date
Application number
ZA919752A
Other languages
English (en)
Inventor
Marc Lang
Lang Marc
Edmond Differding
Differding Edmond
Jaroslav Stanek
Stanek Jaroslav
Original Assignee
Ciba Geigy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy filed Critical Ciba Geigy
Publication of ZA919752B publication Critical patent/ZA919752B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/26—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/32—Antioestrogens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/26—Radicals substituted by halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Quinoline Compounds (AREA)
  • Indole Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Bakery Products And Manufacturing Methods Therefor (AREA)
ZA919752A 1990-12-12 1991-12-11 Fluorine compounds ZA919752B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH392390 1990-12-12

Publications (1)

Publication Number Publication Date
ZA919752B true ZA919752B (en) 1992-08-26

Family

ID=4266402

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA919752A ZA919752B (en) 1990-12-12 1991-12-11 Fluorine compounds

Country Status (18)

Country Link
US (4) US5227393A (ko)
EP (1) EP0490816B1 (ko)
JP (1) JP3133432B2 (ko)
KR (1) KR100214353B1 (ko)
AT (1) ATE155130T1 (ko)
AU (1) AU649499B2 (ko)
CA (1) CA2057338C (ko)
DE (1) DE59108770D1 (ko)
DK (1) DK0490816T3 (ko)
ES (1) ES2104682T3 (ko)
GR (1) GR3024191T3 (ko)
IE (1) IE914312A1 (ko)
IL (1) IL100266A (ko)
NZ (1) NZ240925A (ko)
PH (1) PH30675A (ko)
PT (1) PT99738B (ko)
TW (1) TW210334B (ko)
ZA (1) ZA919752B (ko)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW224461B (ko) * 1990-09-18 1994-06-01 Ciba Geigy Ag
TW210334B (ko) * 1990-12-12 1993-08-01 Ciba Geigy Ag
AU5285593A (en) * 1992-10-21 1994-05-09 Sankyo Company Limited Azole compound
US5426196A (en) * 1993-12-22 1995-06-20 Glaxo Inc. Synthesis of diaryl methanes
IT1286866B1 (it) * 1996-10-28 1998-07-17 Menarini Farma Ind Composti furano-eterociclici,loro preparazione ed uso come inibitori di aromatasi
FI20010905A0 (fi) * 2001-05-02 2001-05-02 Vetcare Oy Uusi eläinlääke
GB0914767D0 (en) * 2009-08-24 2009-09-30 Sterix Ltd Compound
AU2011237592B2 (en) 2010-04-08 2016-10-27 Emory University Substituted androst-4-ene diones
KR101872561B1 (ko) 2011-09-08 2018-06-28 노파르티스 아게 아로마타제 억제제를 포함하는 제약 조성물
EP3180335B1 (en) 2014-08-11 2021-05-05 Angion Biomedica Corporation Cytochrome p450 inhibitors and uses thereof
WO2016109492A1 (en) 2014-12-31 2016-07-07 Angion Biomedica Corp Methods and agents for treating disease
GB201614179D0 (en) * 2016-08-19 2016-10-05 Mereo Biopharma 2 Ltd Dosage regimen for the treatment of endometriosis

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2407305C2 (de) * 1974-02-15 1984-06-28 Bayer Ag, 5090 Leverkusen Triphenyl-1,2,3-triazol-1-yl-methane, Verfahren zu ihrer Herstellung und ihre Verwendung als Fungizide
GB1511195A (en) * 1976-10-18 1978-05-17 Ici America Inc Triazole derivatives
GB1555417A (en) * 1977-04-19 1979-11-07 Ici America Inc Triazole compositions
ZA84652B (en) * 1983-02-02 1985-09-25 Lilly Co Eli Aromatase inhibiting pyrimidine derivatives
US4762836A (en) * 1983-02-02 1988-08-09 Eli Lilly And Company Aromatase inhibitors
GB8305377D0 (en) * 1983-02-25 1983-03-30 Pfizer Ltd Antifungal agents
EP0163606B1 (de) * 1984-05-23 1989-09-06 Ciba-Geigy Ag Mikrobizide 1-Fluor-1-azolyl-2,2-diarylethanderivate
US4609666A (en) * 1984-06-18 1986-09-02 Eli Lilly And Company Aromatase inhibiting derivatives of α,α-bis(4-halophenyl)methyltetrazoles and triazoles
US4757076A (en) * 1984-06-18 1988-07-12 Eli Lilly And Company Method of inhibiting aromatase
US4845227A (en) * 1984-06-18 1989-07-04 Eli Lilly And Company Aromatase inhibitors from azoles
US4764376A (en) * 1984-06-18 1988-08-16 Eli Lilly And Company Method of inhibiting aromatase
US4978672A (en) * 1986-03-07 1990-12-18 Ciba-Geigy Corporation Alpha-heterocyclc substituted tolunitriles
US5071861A (en) * 1986-03-07 1991-12-10 Ciba-Geigy Corporation Alpha-heterocycle substituted tolunitriles
US4937250A (en) * 1988-03-07 1990-06-26 Ciba-Geigy Corporation Alpha-heterocycle substituted tolunitriles
US5352795A (en) * 1986-03-07 1994-10-04 Ciba-Geigy Corporation Alpha-heterocycle substituted tolunitriles
US5112845A (en) * 1986-03-07 1992-05-12 Ciba-Geigy Corporation Alpha-heterocycle substituted tolunitriles
US4749713A (en) * 1986-03-07 1988-06-07 Ciba-Geigy Corporation Alpha-heterocycle substituted tolunitriles
DE3627310A1 (de) * 1986-08-12 1988-02-18 Biotechnolog Forschung Gmbh Pyocyanin-derivate und herstellungsverfahren
JPS63165376A (ja) * 1986-12-27 1988-07-08 Nippon Soda Co Ltd オキサ（チア）ジアゾ−ル誘導体その製造方法及び殺ダニ剤
NZ224714A (en) * 1987-06-01 1990-03-27 Janssen Pharmaceutica Nv Substituted benzotriazole derivatives and pharmaceutical compositions
GB8716650D0 (en) * 1987-07-15 1987-08-19 Ici Plc Use of olefinic compounds
GB8716651D0 (en) * 1987-07-15 1987-08-19 Ici Plc 2-propanol derivatives
DE3811574A1 (de) * 1988-03-31 1989-10-19 Schering Ag N-substituierte imidazole, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln
DE3819903A1 (de) * 1988-06-11 1989-12-21 Basf Ag 1-halogen-1-azolyl-ethan-derivate und diese enthaltende fungizide
GB8818561D0 (en) * 1988-08-04 1988-09-07 Ici Plc Diphenylethane derivatives
ES2084687T3 (es) * 1989-07-14 1996-05-16 Ciba Geigy Ag Benzonitrilos substituidos.
AU7124691A (en) * 1990-02-27 1991-08-29 Ciba-Geigy Ag Benzofurans
TW224461B (ko) * 1990-09-18 1994-06-01 Ciba Geigy Ag
TW210334B (ko) * 1990-12-12 1993-08-01 Ciba Geigy Ag

Also Published As

Publication number Publication date
KR920012049A (ko) 1992-07-25
DE59108770D1 (de) 1997-08-14
US5637605A (en) 1997-06-10
US5457209A (en) 1995-10-10
TW210334B (ko) 1993-08-01
US5227393A (en) 1993-07-13
DK0490816T3 (da) 1997-09-22
ES2104682T3 (es) 1997-10-16
PT99738A (pt) 1992-12-31
CA2057338A1 (en) 1992-06-13
NZ240925A (en) 1995-02-24
EP0490816B1 (de) 1997-07-09
GR3024191T3 (en) 1997-10-31
US5376669A (en) 1994-12-27
IL100266A (en) 1996-05-14
PT99738B (pt) 1999-05-31
PH30675A (en) 1997-09-16
JP3133432B2 (ja) 2001-02-05
AU649499B2 (en) 1994-05-26
IL100266A0 (en) 1992-09-06
IE914312A1 (en) 1992-06-17
CA2057338C (en) 2002-09-17
JPH04300866A (ja) 1992-10-23
EP0490816A3 (en) 1992-12-02
AU8889991A (en) 1992-07-09
EP0490816A2 (de) 1992-06-17
ATE155130T1 (de) 1997-07-15
KR100214353B1 (ko) 1999-08-02

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