ZA919572B - Process for the preparation of(2r)-methyl-4,4,4-trifluorobutylamine or a salt thereof - Google Patents
Process for the preparation of(2r)-methyl-4,4,4-trifluorobutylamine or a salt thereofInfo
- Publication number
- ZA919572B ZA919572B ZA919572A ZA919572A ZA919572B ZA 919572 B ZA919572 B ZA 919572B ZA 919572 A ZA919572 A ZA 919572A ZA 919572 A ZA919572 A ZA 919572A ZA 919572 B ZA919572 B ZA 919572B
- Authority
- ZA
- South Africa
- Prior art keywords
- methyl
- trifluorobutylamine
- butyramide
- preparation
- acylating
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
- C07C209/44—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of carboxylic acids or esters thereof in presence of ammonia or amines, or by reduction of nitriles, carboxylic acid amides, imines or imino-ethers
- C07C209/50—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of carboxylic acids or esters thereof in presence of ammonia or amines, or by reduction of nitriles, carboxylic acid amides, imines or imino-ethers by reduction of carboxylic acid amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
- C07C211/02—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C211/15—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton the carbon skeleton being further substituted by halogen atoms or by nitro or nitroso groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/16—Preparation of optical isomers
- C07C231/18—Preparation of optical isomers by stereospecific synthesis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an alkyl or cycloalkyl radical attached to the ring nitrogen atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Pulmonology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Indole Compounds (AREA)
- Carbon And Carbon Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Glass Compositions (AREA)
- Iron Core Of Rotating Electric Machines (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB909026425A GB9026425D0 (en) | 1990-12-05 | 1990-12-05 | Process |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA919572B true ZA919572B (en) | 1992-10-28 |
Family
ID=10686507
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA919572A ZA919572B (en) | 1990-12-05 | 1991-12-04 | Process for the preparation of(2r)-methyl-4,4,4-trifluorobutylamine or a salt thereof |
Country Status (20)
Country | Link |
---|---|
US (1) | US5274118A (sv) |
EP (1) | EP0489548B1 (sv) |
JP (1) | JP3160041B2 (sv) |
AT (1) | ATE115543T1 (sv) |
AU (1) | AU649498B2 (sv) |
CA (1) | CA2056068C (sv) |
CZ (1) | CZ281659B6 (sv) |
DE (1) | DE69105931T2 (sv) |
DK (1) | DK0489548T3 (sv) |
ES (1) | ES2066373T3 (sv) |
FI (1) | FI109995B (sv) |
GB (1) | GB9026425D0 (sv) |
HU (1) | HU212936B (sv) |
IE (1) | IE65663B1 (sv) |
IL (1) | IL100092A (sv) |
NO (1) | NO176516C (sv) |
NZ (1) | NZ240857A (sv) |
PT (1) | PT99684B (sv) |
SK (1) | SK280473B6 (sv) |
ZA (1) | ZA919572B (sv) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8927981D0 (en) * | 1989-12-11 | 1990-02-14 | Ici Plc | Carbamoyl derivative |
GB9026427D0 (en) * | 1990-12-05 | 1991-01-23 | Ici Plc | Chemical process |
GB9119001D0 (en) * | 1991-09-05 | 1991-10-23 | Ici Plc | Pharmaceutical agents |
JPWO2005005648A1 (ja) * | 2003-07-11 | 2007-09-20 | 三菱ウェルファーマ株式会社 | 新規な光学活性カルボン酸の製造法 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2243977A (en) * | 1938-07-18 | 1941-06-03 | Sandoz Ltd | Process for the preparation of amino-alcohols |
GB8927981D0 (en) * | 1989-12-11 | 1990-02-14 | Ici Plc | Carbamoyl derivative |
US5105014A (en) * | 1991-08-06 | 1992-04-14 | Mallinckrodt Medical, Inc. | Synthesis of vicinal diamines |
-
1990
- 1990-12-05 GB GB909026425A patent/GB9026425D0/en active Pending
-
1991
- 1991-11-19 IL IL10009291A patent/IL100092A/en active IP Right Grant
- 1991-11-22 CA CA002056068A patent/CA2056068C/en not_active Expired - Fee Related
- 1991-11-29 DE DE69105931T patent/DE69105931T2/de not_active Expired - Fee Related
- 1991-11-29 DK DK91311073.0T patent/DK0489548T3/da active
- 1991-11-29 ES ES91311073T patent/ES2066373T3/es not_active Expired - Lifetime
- 1991-11-29 AT AT91311073T patent/ATE115543T1/de not_active IP Right Cessation
- 1991-11-29 EP EP91311073A patent/EP0489548B1/en not_active Expired - Lifetime
- 1991-12-02 HU HU913758A patent/HU212936B/hu not_active IP Right Cessation
- 1991-12-04 NO NO914776A patent/NO176516C/no unknown
- 1991-12-04 AU AU88385/91A patent/AU649498B2/en not_active Ceased
- 1991-12-04 CZ CS913687A patent/CZ281659B6/cs not_active IP Right Cessation
- 1991-12-04 NZ NZ240857A patent/NZ240857A/xx not_active IP Right Cessation
- 1991-12-04 SK SK3687-91A patent/SK280473B6/sk unknown
- 1991-12-04 US US07/803,291 patent/US5274118A/en not_active Expired - Fee Related
- 1991-12-04 PT PT99684A patent/PT99684B/pt not_active IP Right Cessation
- 1991-12-04 FI FI915721A patent/FI109995B/sv not_active IP Right Cessation
- 1991-12-04 ZA ZA919572A patent/ZA919572B/xx unknown
- 1991-12-04 IE IE421991A patent/IE65663B1/en not_active IP Right Cessation
- 1991-12-05 JP JP32180191A patent/JP3160041B2/ja not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CS368791A3 (en) | 1992-09-16 |
DE69105931D1 (de) | 1995-01-26 |
IL100092A (en) | 1996-10-16 |
HU913758D0 (en) | 1992-02-28 |
NO176516C (no) | 1995-04-19 |
FI109995B (sv) | 2002-11-15 |
AU8838591A (en) | 1992-06-11 |
ES2066373T3 (es) | 1995-03-01 |
PT99684B (pt) | 1999-05-31 |
DK0489548T3 (da) | 1995-05-08 |
GB9026425D0 (en) | 1991-01-23 |
FI915721A (fi) | 1992-06-06 |
AU649498B2 (en) | 1994-05-26 |
PT99684A (pt) | 1992-10-30 |
US5274118A (en) | 1993-12-28 |
NO914776D0 (no) | 1991-12-04 |
IE914219A1 (en) | 1992-06-17 |
IL100092A0 (en) | 1992-08-18 |
CZ281659B6 (cs) | 1996-12-11 |
NZ240857A (en) | 1994-05-26 |
CA2056068A1 (en) | 1992-06-06 |
CA2056068C (en) | 2003-05-06 |
IE65663B1 (en) | 1995-11-15 |
JPH04290870A (ja) | 1992-10-15 |
NO176516B (no) | 1995-01-09 |
EP0489548A1 (en) | 1992-06-10 |
ATE115543T1 (de) | 1994-12-15 |
NO914776L (no) | 1992-06-09 |
HU212936B (en) | 1996-12-30 |
SK280473B6 (sk) | 2000-02-14 |
EP0489548B1 (en) | 1994-12-14 |
FI915721A0 (fi) | 1991-12-04 |
JP3160041B2 (ja) | 2001-04-23 |
DE69105931T2 (de) | 1995-05-04 |
HUT61964A (en) | 1993-03-29 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
LU90160I2 (fr) | Naratriptan facultativement sous la forme d'un sel pharmaceutiquement acceptable ou d'un solvate y compris le chlorhydrate de naratriptan | |
PT79808A (en) | Process for the preparation of bicyclic 2-imidalamine derivatives condensed with n-(4-piperidinyl) | |
PL302163A1 (en) | Novel derivatives of benzimidazolone | |
HU900846D0 (en) | Process for preparation of substituted pyrroles | |
LU91083I2 (fr) | Bortezomib ou un des ester pharmaceutiquement acceptables, optionnellement sous forme d'un sel pharmaceutiquement acceptable-Velcade. | |
AU588837B2 (en) | Polypeptide | |
AU639259B2 (en) | Amino acid derivatives with renin-inhibiting properties, a process for the preparation thereof, agents containing these, and the use thereof | |
ZA919572B (en) | Process for the preparation of(2r)-methyl-4,4,4-trifluorobutylamine or a salt thereof | |
ZA909345B (en) | Method of preventing or limiting reperfusion damage | |
AU1413788A (en) | Dihydropyridinamides process for their preparation, and their use in medicaments | |
PT85869A (en) | Process for preparing amino acid derivative anti-convulsant | |
ES8104226A1 (es) | Procedimiento para la preparacion de nuevas imidas de acido ciclobutandicarboxilico | |
AU4547589A (en) | Renin-inhibiting aminodiol derivatives | |
HUT47374A (en) | Fungicide compositions containing /2-cyano-2-oximino-acetyl/-aminoacid derivatives as active components and process for producing the active components | |
FI102748B1 (sv) | Förfarande för framställning av N-(2,6-dialkyl)-2-(2-oxo-1-pyrrolidinyl)acetamidderivat | |
CA2418227A1 (en) | Process for the preparation of 5-hydroxymethyl 2-oxazolidinone and novel intermediate | |
EP0297560A3 (en) | Imides; a process for their production and a process for the production of dipeptides using them | |
CA2186023A1 (en) | Process for preparing 2-piperazine carboxylic acid derivatives | |
NZ244870A (en) | Preparative process for 2-c -c alk-1-en-1-ylbenzenesulphonic acid n-[4-(5-cyclopentyloxyamino-1-methylindol-3-ylmethyl)-3-methoxybenzoy l]amides;dicyclopentyl dicarbonate as acylating agent | |
KR920012030A (ko) | 약학적 중간 물질의 제조방법 | |
UA29372C2 (uk) | Спосіб одержання n-(1-метоксипроп-2-іл)-2,4-диметил-3амінотіофену, 2,4-диметил-2,3-дигідротіофен-3-он як проміжний продукт та його похідні як вихідні продукти | |
ES2017278A6 (es) | Procedimiento de obtencion de un derivado del 2-amino-1-fenilpropan-1-ol. |