PT99684A - Processo para a preparacao de (2r)-metil-4,4,4-trifluoro-butil-amina e dos seus sais de adicao de acido - Google Patents

Processo para a preparacao de (2r)-metil-4,4,4-trifluoro-butil-amina e dos seus sais de adicao de acido

Info

Publication number
PT99684A
PT99684A PT99684A PT9968491A PT99684A PT 99684 A PT99684 A PT 99684A PT 99684 A PT99684 A PT 99684A PT 9968491 A PT9968491 A PT 9968491A PT 99684 A PT99684 A PT 99684A
Authority
PT
Portugal
Prior art keywords
methyl
trifluoro
preparation
butyramide
amine
Prior art date
Application number
PT99684A
Other languages
English (en)
Other versions
PT99684B (pt
Inventor
Robert Toms Jacobs
Andrew George Brewster
George Joseph Sependa
Jing Kwong Yee
Peter Robert Bernstein
Original Assignee
Ici Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ici Plc filed Critical Ici Plc
Publication of PT99684A publication Critical patent/PT99684A/pt
Publication of PT99684B publication Critical patent/PT99684B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/44—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of carboxylic acids or esters thereof in presence of ammonia or amines, or by reduction of nitriles, carboxylic acid amides, imines or imino-ethers
    • C07C209/50—Preparation of compounds containing amino groups bound to a carbon skeleton by reduction of carboxylic acids or esters thereof in presence of ammonia or amines, or by reduction of nitriles, carboxylic acid amides, imines or imino-ethers by reduction of carboxylic acid amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
    • C07C211/02—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C211/15—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton the carbon skeleton being further substituted by halogen atoms or by nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/16—Preparation of optical isomers
    • C07C231/18—Preparation of optical isomers by stereospecific synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an alkyl or cycloalkyl radical attached to the ring nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pulmonology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Carbon And Carbon Compounds (AREA)
  • Glass Compositions (AREA)
  • Iron Core Of Rotating Electric Machines (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PT99684A 1990-12-05 1991-12-04 Processo para a preparacao de (2r)-metil-4,4,4-trifluoro-butil-amina e dos seus sais de adicao de acido PT99684B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB909026425A GB9026425D0 (en) 1990-12-05 1990-12-05 Process

Publications (2)

Publication Number Publication Date
PT99684A true PT99684A (pt) 1992-10-30
PT99684B PT99684B (pt) 1999-05-31

Family

ID=10686507

Family Applications (1)

Application Number Title Priority Date Filing Date
PT99684A PT99684B (pt) 1990-12-05 1991-12-04 Processo para a preparacao de (2r)-metil-4,4,4-trifluoro-butil-amina e dos seus sais de adicao de acido

Country Status (20)

Country Link
US (1) US5274118A (pt)
EP (1) EP0489548B1 (pt)
JP (1) JP3160041B2 (pt)
AT (1) ATE115543T1 (pt)
AU (1) AU649498B2 (pt)
CA (1) CA2056068C (pt)
CZ (1) CZ281659B6 (pt)
DE (1) DE69105931T2 (pt)
DK (1) DK0489548T3 (pt)
ES (1) ES2066373T3 (pt)
FI (1) FI109995B (pt)
GB (1) GB9026425D0 (pt)
HU (1) HU212936B (pt)
IE (1) IE65663B1 (pt)
IL (1) IL100092A (pt)
NO (1) NO176516C (pt)
NZ (1) NZ240857A (pt)
PT (1) PT99684B (pt)
SK (1) SK280473B6 (pt)
ZA (1) ZA919572B (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8927981D0 (en) * 1989-12-11 1990-02-14 Ici Plc Carbamoyl derivative
GB9026427D0 (en) * 1990-12-05 1991-01-23 Ici Plc Chemical process
GB9119001D0 (en) * 1991-09-05 1991-10-23 Ici Plc Pharmaceutical agents
WO2005005648A1 (ja) * 2003-07-11 2005-01-20 Mitsubishi Pharma Corporation 新規な光学活性カルボン酸の製造法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2243977A (en) * 1938-07-18 1941-06-03 Sandoz Ltd Process for the preparation of amino-alcohols
GB8927981D0 (en) * 1989-12-11 1990-02-14 Ici Plc Carbamoyl derivative
US5105014A (en) * 1991-08-06 1992-04-14 Mallinckrodt Medical, Inc. Synthesis of vicinal diamines

Also Published As

Publication number Publication date
CA2056068C (en) 2003-05-06
EP0489548B1 (en) 1994-12-14
DK0489548T3 (da) 1995-05-08
NO914776L (no) 1992-06-09
HU212936B (en) 1996-12-30
IE65663B1 (en) 1995-11-15
NO176516C (no) 1995-04-19
CS368791A3 (en) 1992-09-16
HUT61964A (en) 1993-03-29
EP0489548A1 (en) 1992-06-10
DE69105931T2 (de) 1995-05-04
NO914776D0 (no) 1991-12-04
FI915721A0 (fi) 1991-12-04
CA2056068A1 (en) 1992-06-06
AU8838591A (en) 1992-06-11
NZ240857A (en) 1994-05-26
AU649498B2 (en) 1994-05-26
FI915721A (fi) 1992-06-06
IL100092A (en) 1996-10-16
CZ281659B6 (cs) 1996-12-11
DE69105931D1 (de) 1995-01-26
ES2066373T3 (es) 1995-03-01
GB9026425D0 (en) 1991-01-23
HU913758D0 (en) 1992-02-28
ZA919572B (en) 1992-10-28
IL100092A0 (en) 1992-08-18
ATE115543T1 (de) 1994-12-15
JP3160041B2 (ja) 2001-04-23
FI109995B (fi) 2002-11-15
IE914219A1 (en) 1992-06-17
SK280473B6 (sk) 2000-02-14
US5274118A (en) 1993-12-28
PT99684B (pt) 1999-05-31
JPH04290870A (ja) 1992-10-15
NO176516B (no) 1995-01-09

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Legal Events

Date Code Title Description
BB1A Laying open of patent application

Effective date: 19920609

FG3A Patent granted, date of granting

Effective date: 19990210

PC3A Transfer or assignment

Free format text: ASTRAZENECA UK LIMITED GB

Effective date: 20040722

PD3A Change of proprietorship

Free format text: SYNGENTA LIMITED GB

Effective date: 20040722

MM3A Annulment or lapse

Effective date: 20050810