ZA913135B - Azatetracycle compounds - Google Patents
Azatetracycle compoundsInfo
- Publication number
- ZA913135B ZA913135B ZA913135A ZA913135A ZA913135B ZA 913135 B ZA913135 B ZA 913135B ZA 913135 A ZA913135 A ZA 913135A ZA 913135 A ZA913135 A ZA 913135A ZA 913135 B ZA913135 B ZA 913135B
- Authority
- ZA
- South Africa
- Prior art keywords
- compounds
- chem
- azatetracycle
- azatetracycle compounds
- mammals
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/18—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Nutrition Science (AREA)
- Anesthesiology (AREA)
- Otolaryngology (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Cephalosporin Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US51539190A | 1990-04-27 | 1990-04-27 | |
US07/682,993 US5140023A (en) | 1990-04-27 | 1991-04-12 | Azatetracycle compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA913135B true ZA913135B (en) | 1992-07-29 |
Family
ID=27058488
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA913135A ZA913135B (en) | 1990-04-27 | 1991-04-25 | Azatetracycle compounds |
Country Status (18)
Country | Link |
---|---|
US (2) | US5140023A (xx) |
EP (1) | EP0454121B1 (xx) |
JP (1) | JP3145728B2 (xx) |
KR (1) | KR0183423B1 (xx) |
AT (1) | ATE145207T1 (xx) |
AU (1) | AU630555B2 (xx) |
CA (1) | CA2041224C (xx) |
DE (1) | DE69123076T2 (xx) |
DK (1) | DK0454121T3 (xx) |
ES (1) | ES2094166T3 (xx) |
FI (1) | FI94530C (xx) |
GR (1) | GR3021607T3 (xx) |
IE (1) | IE76450B1 (xx) |
IL (1) | IL97952A0 (xx) |
NO (1) | NO178765C (xx) |
NZ (1) | NZ237948A (xx) |
PT (1) | PT97486B (xx) |
ZA (1) | ZA913135B (xx) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5516782A (en) * | 1991-03-07 | 1996-05-14 | G. D. Searle & Co. | New meso-azacyclic aromatic acid amides and esters as novel serotonergic agents |
AU1578692A (en) * | 1991-03-07 | 1992-10-06 | G.D. Searle & Co. | New meso-azacyclic aromatic acid amides and esters as novel serotonergic agents |
US5234921A (en) * | 1991-03-07 | 1993-08-10 | G. D. Searle & Co. | Meso-azacyclic amides of imidazopyridine carboxylic acids and analogs thereof as pharmaceuticals |
US5955470A (en) * | 1991-06-11 | 1999-09-21 | Merrell Pharmaceuticals, Inc. | Derivatives of amide analogs of certain methano bridged quinolizines |
US5280028A (en) * | 1992-06-24 | 1994-01-18 | G. D. Searle & Co. | Benzimidazole compounds |
GB9214184D0 (en) * | 1992-07-03 | 1992-08-12 | Smithkline Beecham Plc | Pharmaceuticals |
US5840903A (en) * | 1992-07-27 | 1998-11-24 | G. D. Searle & Co. | 4-aminomethyl-1-azaadamantane derived benzamides |
US5354757A (en) * | 1992-12-15 | 1994-10-11 | G. D. Searle & Co. | Azanoradamantanes |
US5650535A (en) * | 1994-06-30 | 1997-07-22 | G. D. Searle & Co. | Process for the preparation of azanoradamantane benzamides |
JP2000026311A (ja) * | 1998-07-02 | 2000-01-25 | Amano Pharmaceut Co Ltd | 胃排出能亢進剤組成物 |
US6451806B2 (en) | 1999-09-29 | 2002-09-17 | Adolor Corporation | Methods and compositions involving opioids and antagonists thereof |
US6469030B2 (en) | 1999-11-29 | 2002-10-22 | Adolor Corporation | Methods for the treatment and prevention of ileus |
US6638928B1 (en) * | 2002-12-03 | 2003-10-28 | Vela Pharmaceuticals, Inc. | Treatment of irritable bowel syndrome and nonulcer dyspepsia with substituted 2,3-benzodiazepines |
GB0321091D0 (en) | 2003-09-09 | 2003-10-08 | Alizyme Therapeutics Ltd | Synthesis |
EP2124562B1 (en) | 2007-03-09 | 2016-04-20 | Second Genome, Inc. | Bicycloheteroaryl compounds as p2x7 modulators and uses thereof |
CA2679870A1 (en) * | 2007-03-23 | 2008-10-02 | Abbott Laboratories | Azaadamantane ester and carbamate derivatives and methods of use thereof |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL59004A0 (en) * | 1978-12-30 | 1980-03-31 | Beecham Group Ltd | Substituted benzamides their preparation and pharmaceutical compositions containing them |
DE3275296D1 (en) * | 1981-10-01 | 1987-03-05 | Beecham Group Plc | Azabicyclo-(3,3,1)-nonylbenzamide derivatives, processes for their preparation, and pharmaceutical compositions containing them |
EP0093488A3 (en) * | 1982-03-18 | 1984-05-23 | Beecham Group Plc | Nortropyl benzopyrrolinone compounds, process for their preparation and pharmaceutical compositions containing them |
IE56226B1 (en) * | 1982-04-14 | 1991-05-22 | Beecham Group Plc | Substituted azabicyclo compounds,process for their preparation and pharmaceutical compositions containing them |
FR2531083B1 (fr) * | 1982-06-29 | 1986-11-28 | Sandoz Sa | Nouveaux derives de la piperidine, leur preparation et leur utilisation comme medicaments |
BG48681A3 (en) * | 1982-12-14 | 1991-04-15 | Ciba - Geigy Ag | Fungicide means |
DE3429830A1 (de) * | 1983-08-26 | 1985-03-07 | Sandoz-Patent-GmbH, 7850 Lörrach | Automatische carbonsaeure- und sulfonsaeureester oder -amide |
FR2557110B1 (fr) * | 1983-12-23 | 1989-11-24 | Sandoz Sa | Nouveaux derives d'amines cycliques, leur preparation et leur utilisation comme medicaments |
DE3587151T2 (de) * | 1984-12-20 | 1993-07-15 | Sandoz Ag | Behandlung von gastrointestinalkrankheiten durch anwendung von 5-ht3-antagonisten. |
CH667657A5 (de) * | 1985-01-07 | 1988-10-31 | Sandoz Ag | Carbocyclische und heterocyclische carbonylmethylen- und methylpiperidine und -pyrrolidine. |
DE3689974T2 (de) * | 1985-03-14 | 1994-11-03 | Beecham Group Plc | Arzneimittel zur Behandlung von Emesis. |
GB8523211D0 (en) * | 1985-09-19 | 1985-10-23 | Beecham Group Plc | Compounds |
EP0220011A3 (en) * | 1985-10-12 | 1990-01-03 | Beecham Group Plc | Use of azabicloalkylbenzamides in the treatment of gastrointestinal motility disorders, migraine, emesis, cluster headaches, trigeminal neuralgia and arrhythmia |
GB8527052D0 (en) * | 1985-11-02 | 1985-12-04 | Beecham Group Plc | Compounds |
DE3687980T2 (de) * | 1986-01-07 | 1993-06-17 | Beecham Group Plc | Indolderivate mit einer azabicyclischen seitenkette, verfahren zu ihrer herstellung, zwischenprodukte und pharmazeutische zusammensetzungen. |
EP0235878A3 (en) * | 1986-01-16 | 1989-06-14 | Beecham Group Plc | Novel compounds |
EP0315390B1 (en) * | 1987-11-04 | 1994-07-20 | Beecham Group Plc | Novel 4-oxobenzotriazines and 4-oxoquinazolines |
IE63474B1 (en) * | 1987-12-24 | 1995-04-19 | Wyeth John & Brother Ltd | Heterocyclic compounds |
-
1991
- 1991-04-12 US US07/682,993 patent/US5140023A/en not_active Ceased
- 1991-04-25 NO NO911648A patent/NO178765C/no unknown
- 1991-04-25 DK DK91106697.5T patent/DK0454121T3/da active
- 1991-04-25 DE DE69123076T patent/DE69123076T2/de not_active Expired - Fee Related
- 1991-04-25 CA CA002041224A patent/CA2041224C/en not_active Expired - Fee Related
- 1991-04-25 FI FI912013A patent/FI94530C/fi not_active IP Right Cessation
- 1991-04-25 ZA ZA913135A patent/ZA913135B/xx unknown
- 1991-04-25 AT AT91106697T patent/ATE145207T1/de not_active IP Right Cessation
- 1991-04-25 EP EP91106697A patent/EP0454121B1/en not_active Expired - Lifetime
- 1991-04-25 KR KR1019910006678A patent/KR0183423B1/ko not_active IP Right Cessation
- 1991-04-25 IL IL97952A patent/IL97952A0/xx not_active IP Right Cessation
- 1991-04-25 ES ES91106697T patent/ES2094166T3/es not_active Expired - Lifetime
- 1991-04-26 JP JP09676191A patent/JP3145728B2/ja not_active Expired - Fee Related
- 1991-04-26 AU AU75951/91A patent/AU630555B2/en not_active Ceased
- 1991-04-26 IE IE142091A patent/IE76450B1/en not_active IP Right Cessation
- 1991-04-26 NZ NZ237948A patent/NZ237948A/en unknown
- 1991-04-26 PT PT97486A patent/PT97486B/pt not_active IP Right Cessation
-
1994
- 1994-08-18 US US08/292,894 patent/USRE35218E/en not_active Expired - Lifetime
-
1996
- 1996-11-14 GR GR960402848T patent/GR3021607T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
CA2041224A1 (en) | 1991-10-28 |
CA2041224C (en) | 2002-07-09 |
DK0454121T3 (da) | 1996-12-02 |
IL97952A0 (en) | 1992-06-21 |
IE911420A1 (en) | 1991-11-06 |
PT97486A (pt) | 1992-01-31 |
KR0183423B1 (ko) | 1999-05-01 |
DE69123076D1 (de) | 1996-12-19 |
NO911648D0 (no) | 1991-04-25 |
JP3145728B2 (ja) | 2001-03-12 |
GR3021607T3 (en) | 1997-02-28 |
FI94530B (fi) | 1995-06-15 |
ATE145207T1 (de) | 1996-11-15 |
NO178765B (no) | 1996-02-19 |
AU7595191A (en) | 1991-11-07 |
JPH04225979A (ja) | 1992-08-14 |
EP0454121A3 (en) | 1992-07-08 |
US5140023A (en) | 1992-08-18 |
NO178765C (no) | 1996-05-29 |
FI94530C (fi) | 1995-09-25 |
ES2094166T3 (es) | 1997-01-16 |
EP0454121A2 (en) | 1991-10-30 |
NZ237948A (en) | 1994-05-26 |
FI912013A0 (fi) | 1991-04-25 |
USRE35218E (en) | 1996-04-23 |
IE76450B1 (en) | 1997-10-22 |
PT97486B (pt) | 1998-08-31 |
FI912013A (fi) | 1991-10-28 |
EP0454121B1 (en) | 1996-11-13 |
AU630555B2 (en) | 1992-10-29 |
NO911648L (no) | 1991-10-28 |
DE69123076T2 (de) | 1997-04-03 |
KR910018382A (ko) | 1991-11-30 |
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