ZA909141B - Therapeutically active chloro substituted benzimidazoles,processes for their preparation as well as their use - Google Patents

Therapeutically active chloro substituted benzimidazoles,processes for their preparation as well as their use

Info

Publication number
ZA909141B
ZA909141B ZA909141A ZA909141A ZA909141B ZA 909141 B ZA909141 B ZA 909141B ZA 909141 A ZA909141 A ZA 909141A ZA 909141 A ZA909141 A ZA 909141A ZA 909141 B ZA909141 B ZA 909141B
Authority
ZA
South Africa
Prior art keywords
processes
preparation
well
therapeutically active
substituted benzimidazoles
Prior art date
Application number
ZA909141A
Other languages
English (en)
Inventor
Arne Elof Braendstroem
Elof Braendstroem Arne
Per Lennart Lindberg
Lennart Lindberg Per
Carl Ingemar Starke
Ingemar Starke Carl
Gunnel Elisabeth Sunden
Elisabeth Sunden Gunnel
Original Assignee
Haessle Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Haessle Ab filed Critical Haessle Ab
Publication of ZA909141B publication Critical patent/ZA909141B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA909141A 1989-12-20 1990-11-14 Therapeutically active chloro substituted benzimidazoles,processes for their preparation as well as their use ZA909141B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/454,049 US4965269A (en) 1989-12-20 1989-12-20 Therapeutically active chloro substituted benzimidazoles

Publications (1)

Publication Number Publication Date
ZA909141B true ZA909141B (en) 1991-08-28

Family

ID=23803085

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA909141A ZA909141B (en) 1989-12-20 1990-11-14 Therapeutically active chloro substituted benzimidazoles,processes for their preparation as well as their use

Country Status (10)

Country Link
US (1) US4965269A (fr)
CN (1) CN1052671A (fr)
AU (1) AU6973991A (fr)
IE (1) IE904249A1 (fr)
IL (1) IL96398A0 (fr)
IS (1) IS3660A7 (fr)
PL (1) PL288336A1 (fr)
PT (1) PT96257A (fr)
WO (1) WO1991009029A1 (fr)
ZA (1) ZA909141B (fr)

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US20030158220A1 (en) * 1997-11-03 2003-08-21 Foss Joseph F. Use of methylnaltrexone and related compounds to treat chronic opioid use side effects
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CN100396675C (zh) 1998-08-10 2008-06-25 加利福尼亚州大学董事会 质子泵抑制剂的前药
US20040248941A1 (en) * 2001-09-25 2004-12-09 Keiji Kamiyama Benzimidazone compound, process for producing the same, and use thereof
CA2489470A1 (fr) * 2002-06-14 2003-12-24 Takeda Pharmaceutical Company Limited Promedicament et procede de production de celui-ci
WO2004009583A2 (fr) * 2002-07-19 2004-01-29 Garst Michael E Promedicaments des inhibiteurs de la pompe a protons
MY148805A (en) 2002-10-16 2013-05-31 Takeda Pharmaceutical Controlled release preparation
WO2004091665A1 (fr) * 2003-04-08 2004-10-28 Progenics Pharmaceuticals, Inc. Traitement combine de la constipation comprenant un laxatif et un antagoniste des opioides a action peripherique
CA2521369A1 (fr) * 2003-04-08 2004-10-28 Progenics Pharmaceuticals, Inc. Utilisation d'antagonistes des opioides peripheriques, en particulier de methylnaltrexone, dans le traitement du syndrome du colon irritable
EP1615646B2 (fr) 2003-04-08 2022-07-27 Progenics Pharmaceuticals, Inc. Formulations pharmaceutiques contenant de la methylnaltrexone
CA2529984C (fr) * 2003-06-26 2012-09-25 Isa Odidi Capsules contenant un inhibiteur de la pompe a protons comprenant des unites secondaires differemment structurees permettant une liberation retardee de l'ingredient actif
WO2005039640A1 (fr) * 2003-10-03 2005-05-06 Allergan Inc. Compositions contenant des peptides en trefle et/ou des mucoadhesifs et des promedicaments d'un inhibiteur de pompe a proton
US20050075371A1 (en) * 2003-10-03 2005-04-07 Allergan, Inc. Methods and compositions for the oral administration of prodrugs of proton pump inhibitors
JP2007523164A (ja) * 2004-02-18 2007-08-16 アラーガン、インコーポレイテッド プロトンポンプインヒビターに関連する化合物の静脈内投与のための方法および組成物
US20070060621A1 (en) * 2004-02-18 2007-03-15 Hughes Patrick M Methods and compositions for the administration of prodrugs of proton pump inhibitors
JP2007532677A (ja) * 2004-04-16 2007-11-15 サンタラス インコーポレイティッド プロトンポンプ阻害剤、緩衝剤、および運動促進薬の組み合わせ
US8394409B2 (en) 2004-07-01 2013-03-12 Intellipharmaceutics Corp. Controlled extended drug release technology
US10624858B2 (en) 2004-08-23 2020-04-21 Intellipharmaceutics Corp Controlled release composition using transition coating, and method of preparing same
CA2595329A1 (fr) * 2005-01-20 2006-07-27 Progenics Pharmaceuticals, Inc. Utilisation de methylnaltrexone et de composes apparentes pour traiter un dysfonctionnement gastrointestinal post-operatoire
JP5241484B2 (ja) 2005-03-07 2013-07-17 ザ ユニヴァーシティー オヴ シカゴ 内皮細胞増殖及び内皮細胞遊走を減弱するためのオピオイドアンタゴニストの使用
US8524731B2 (en) 2005-03-07 2013-09-03 The University Of Chicago Use of opioid antagonists to attenuate endothelial cell proliferation and migration
US8518962B2 (en) 2005-03-07 2013-08-27 The University Of Chicago Use of opioid antagonists
US9662325B2 (en) 2005-03-07 2017-05-30 The University Of Chicago Use of opioid antagonists to attenuate endothelial cell proliferation and migration
AR057035A1 (es) 2005-05-25 2007-11-14 Progenics Pharm Inc SíNTESIS DE (R)-N-METILNALTREXONA, COMPOSICIONES FARMACÉUTICAS Y USOS
AR057325A1 (es) 2005-05-25 2007-11-28 Progenics Pharm Inc Sintesis de (s)-n-metilnaltrexona, composiciones farmaceuticas y usos
US20080194611A1 (en) * 2005-06-03 2008-08-14 Alverdy John C Modulation of Cell Barrier Dysfunction
US10064828B1 (en) 2005-12-23 2018-09-04 Intellipharmaceutics Corp. Pulsed extended-pulsed and extended-pulsed pulsed drug delivery systems
JP5457830B2 (ja) 2006-04-03 2014-04-02 オディディ，イサ オルガノゾル被膜を含む制御放出送達デバイス
US10960077B2 (en) 2006-05-12 2021-03-30 Intellipharmaceutics Corp. Abuse and alcohol resistant drug composition
US20100317689A1 (en) * 2006-09-19 2010-12-16 Garst Michael E Prodrugs of proton pump inhibitors including the 1h-imidazo[4,5-b] pyridine moiety
US20080103169A1 (en) 2006-10-27 2008-05-01 The Curators Of The University Of Missouri Compositions comprising acid labile proton pump inhibiting agents, at least one other pharmaceutically active agent and methods of using same
US20080194307A1 (en) * 2007-02-13 2008-08-14 Jeff Sanger Sports-based game of chance
TWI553009B (zh) 2007-03-29 2016-10-11 普吉尼製藥公司 末梢性類鴉片受體拮抗劑及其用途
PL2565195T3 (pl) 2007-03-29 2015-10-30 Wyeth Llc Obwodowy receptor opioidowy i jego antagoniści oraz ich zastosowania
AU2008233133B2 (en) 2007-03-29 2014-03-27 Progenics Pharmaceuticals, Inc. Crystal forms of (R) -N-methylnaltrexone bromide and uses thereof
KR101581480B1 (ko) 2008-02-06 2015-12-30 프로제닉스 파머슈티컬스, 인코포레이티드 (ｒ),(ｒ)-2,2'-비스-메틸날트렉손의 제조법 및 용도
EP2252274A4 (fr) 2008-02-20 2011-05-11 Univ Missouri Composition comprenant une combinaison d'oméprazole et de lansoprazole, et un agent tampon, et ses méthodes d'utilisation
US8685995B2 (en) 2008-03-21 2014-04-01 The University Of Chicago Treatment with opioid antagonists and mTOR inhibitors
CA2676881C (fr) 2008-09-30 2017-04-25 Wyeth Antagonistes de recepteurs opioides peripheriques, et leurs utilisations

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SE8301182D0 (sv) * 1983-03-04 1983-03-04 Haessle Ab Novel compounds
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Also Published As

Publication number Publication date
CN1052671A (zh) 1991-07-03
IE904249A1 (en) 1991-07-03
AU6973991A (en) 1991-07-18
US4965269A (en) 1990-10-23
WO1991009029A1 (fr) 1991-06-27
PT96257A (pt) 1991-09-30
PL288336A1 (en) 1991-12-02
IS3660A7 (is) 1991-06-21
IL96398A0 (en) 1991-08-16

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