ZA906049B - 1-(pyridinylamino)-2-pyrrolidinones,a process for their preparation and their use as medicaments - Google Patents
1-(pyridinylamino)-2-pyrrolidinones,a process for their preparation and their use as medicamentsInfo
- Publication number
- ZA906049B ZA906049B ZA906049A ZA906049A ZA906049B ZA 906049 B ZA906049 B ZA 906049B ZA 906049 A ZA906049 A ZA 906049A ZA 906049 A ZA906049 A ZA 906049A ZA 906049 B ZA906049 B ZA 906049B
- Authority
- ZA
- South Africa
- Prior art keywords
- pyridinylamino
- pyrrolidinones
- loweralkyl
- aryl
- medicaments
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/388,413 US4994472A (en) | 1989-08-02 | 1989-08-02 | 1-(pyridinylamino)-2-pyrrolidinones as pain relievers |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA906049B true ZA906049B (en) | 1991-04-24 |
Family
ID=23534027
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA906049A ZA906049B (en) | 1989-08-02 | 1990-08-01 | 1-(pyridinylamino)-2-pyrrolidinones,a process for their preparation and their use as medicaments |
Country Status (17)
Country | Link |
---|---|
US (1) | US4994472A (ko) |
EP (1) | EP0413191B1 (ko) |
JP (1) | JPH0674264B2 (ko) |
KR (1) | KR0164437B1 (ko) |
AT (1) | ATE109142T1 (ko) |
AU (1) | AU635051B2 (ko) |
CA (1) | CA2022484C (ko) |
DE (1) | DE69011013T2 (ko) |
DK (1) | DK0413191T3 (ko) |
ES (1) | ES2059929T3 (ko) |
FI (1) | FI903818A0 (ko) |
IE (1) | IE65117B1 (ko) |
IL (1) | IL95250A (ko) |
NO (1) | NO903388L (ko) |
NZ (1) | NZ234724A (ko) |
PT (1) | PT94878B (ko) |
ZA (1) | ZA906049B (ko) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5356908A (en) * | 1989-04-21 | 1994-10-18 | E. I. Du Pont De Nemours And Company | Fungicidal oxazolidinones |
EP0435843B1 (en) * | 1989-12-27 | 1994-06-15 | Monsanto Company | Substituted pyridine compounds |
AUPM656594A0 (en) * | 1994-06-30 | 1994-07-21 | Orbital Engine Company (Australia) Proprietary Limited | A method and apparatus relating to control of the operation of an internal combustion engine |
DK0892796T3 (da) * | 1996-04-12 | 2001-11-19 | Aventis Pharma Inc | Isatinderivater som acetylcholinesteraseinhibitorer og analgetika |
US6100276A (en) * | 1996-04-12 | 2000-08-08 | Aventis Pharmaceuticals Inc. | Isatin derivatives as acetylcholinesterase inhibitors and analgesics |
US6825229B2 (en) | 2002-03-07 | 2004-11-30 | Blanchette Rockefeller Neurosciences Institute | Methods for Alzheimer's Disease treatment and cognitive enhancement |
US20050065205A1 (en) | 2002-03-07 | 2005-03-24 | Daniel Alkon | Methods for Alzheimer's disease treatment and cognitive enhance |
EP1551387A4 (en) * | 2002-07-02 | 2007-10-10 | Brni Neurosciences Inst | PKC ACTIVATION AS A MEANS TO GAIN THE SAPP-A SECRETION AND IMPROVE THE COGNITION USING BRYOSTATIN-TYPE COMPOUNDS |
TW201207390A (en) | 2004-05-18 | 2012-02-16 | Brni Neurosciences Inst | Method for screening agent for antidepressant activity |
GB0412019D0 (en) * | 2004-05-28 | 2004-06-30 | Novartis Ag | Organic compounds |
WO2007016202A1 (en) | 2005-07-29 | 2007-02-08 | Blanchette Rockefeller Neurosciences Institute | Use of a pkc activator, alone or combined with a pkc inhibitor to enhance long term memory |
CA2873179A1 (en) | 2007-02-09 | 2008-08-21 | Blanchette Rockefeller Neurosciences Institute | Use of bryostatins and neristatins in the treatment of cognitive impairment due to head trauma |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1670184A1 (de) * | 1967-01-20 | 1971-01-21 | Boehringer Sohn Ingelheim | Verfahren zur Herstellung heterocyclisch substituierter Hydrazino-imidazoline-(2) |
US4260767A (en) * | 1979-12-26 | 1981-04-07 | American Cyanamid Company | 2-Pyridylhydrazides |
US4324884A (en) * | 1980-09-25 | 1982-04-13 | General Electric Company | Organic amine catalyzed method for making polyetherimide |
US4752610A (en) * | 1985-12-04 | 1988-06-21 | Hoechst-Roussel Pharmaceuticals Inc. | N-(pyrrol-1-yl)pyridinamines having memory enhancing properties |
US4792562A (en) * | 1985-12-04 | 1988-12-20 | Hoechst-Roussel Pharmaceuticals, Inc. | N-(pyrrol-1-yl)pyridinamines having memory enhancing activity |
JPH0699307B2 (ja) * | 1987-08-20 | 1994-12-07 | キッセイ薬品工業株式会社 | 抗痴呆剤 |
US4868190A (en) * | 1988-12-27 | 1989-09-19 | Hoechst-Roussel Pharmaceuticals, Inc. | N-pyridinyl-9H-carbazol-9-amines |
-
1989
- 1989-08-02 US US07/388,413 patent/US4994472A/en not_active Expired - Lifetime
-
1990
- 1990-07-31 EP EP90114659A patent/EP0413191B1/en not_active Expired - Lifetime
- 1990-07-31 NZ NZ234724A patent/NZ234724A/en unknown
- 1990-07-31 FI FI903818A patent/FI903818A0/fi not_active Application Discontinuation
- 1990-07-31 IL IL9525090A patent/IL95250A/en active IP Right Revival
- 1990-07-31 AT AT90114659T patent/ATE109142T1/de not_active IP Right Cessation
- 1990-07-31 DK DK90114659.7T patent/DK0413191T3/da active
- 1990-07-31 ES ES90114659T patent/ES2059929T3/es not_active Expired - Lifetime
- 1990-07-31 DE DE69011013T patent/DE69011013T2/de not_active Expired - Lifetime
- 1990-08-01 IE IE278690A patent/IE65117B1/en not_active IP Right Cessation
- 1990-08-01 KR KR1019900011816A patent/KR0164437B1/ko not_active IP Right Cessation
- 1990-08-01 JP JP2202617A patent/JPH0674264B2/ja not_active Expired - Lifetime
- 1990-08-01 CA CA002022484A patent/CA2022484C/en not_active Expired - Fee Related
- 1990-08-01 AU AU60002/90A patent/AU635051B2/en not_active Ceased
- 1990-08-01 PT PT94878A patent/PT94878B/pt not_active IP Right Cessation
- 1990-08-01 ZA ZA906049A patent/ZA906049B/xx unknown
- 1990-08-01 NO NO90903388A patent/NO903388L/no unknown
Also Published As
Publication number | Publication date |
---|---|
AU635051B2 (en) | 1993-03-11 |
US4994472A (en) | 1991-02-19 |
KR0164437B1 (ko) | 1999-01-15 |
AU6000290A (en) | 1991-02-07 |
IE65117B1 (en) | 1995-10-04 |
NO903388L (no) | 1991-02-04 |
DE69011013T2 (de) | 1994-12-22 |
NO903388D0 (no) | 1990-08-01 |
DK0413191T3 (da) | 1994-10-24 |
IL95250A (en) | 1994-01-25 |
PT94878B (pt) | 1997-08-29 |
KR910004597A (ko) | 1991-03-29 |
ES2059929T3 (es) | 1994-11-16 |
IE902786A1 (en) | 1991-02-27 |
EP0413191A1 (en) | 1991-02-20 |
ATE109142T1 (de) | 1994-08-15 |
JPH0368572A (ja) | 1991-03-25 |
IL95250A0 (en) | 1991-06-10 |
CA2022484C (en) | 2000-10-17 |
CA2022484A1 (en) | 1991-02-03 |
PT94878A (pt) | 1991-04-18 |
NZ234724A (en) | 1992-01-29 |
JPH0674264B2 (ja) | 1994-09-21 |
EP0413191B1 (en) | 1994-07-27 |
DE69011013D1 (de) | 1994-09-01 |
FI903818A0 (fi) | 1990-07-31 |
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