ZA891162B - Cephalosporin derivatives and processes for their preparation - Google Patents

Cephalosporin derivatives and processes for their preparation

Info

Publication number
ZA891162B
ZA891162B ZA891162A ZA891162A ZA891162B ZA 891162 B ZA891162 B ZA 891162B ZA 891162 A ZA891162 A ZA 891162A ZA 891162 A ZA891162 A ZA 891162A ZA 891162 B ZA891162 B ZA 891162B
Authority
ZA
South Africa
Prior art keywords
preparation
processes
cephalosporin derivatives
cephem derivatives
image
Prior art date
Application number
ZA891162A
Other languages
English (en)
Inventor
Friedhelm Adam
Adam Friedhelm
Juergen Blumbach
Blumbach Juergen
Walter Duerckheimer
Duerckheimer Walter
Gerd Fischer
Fischer Gerd
Burghard Mencke
Mencke Burghard
Dieter Isert
Isert Dieter
Gerhard Seibert
Seibert Gerhard
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of ZA891162B publication Critical patent/ZA891162B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • C07D501/34—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA891162A 1988-02-17 1989-02-15 Cephalosporin derivatives and processes for their preparation ZA891162B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3804841A DE3804841A1 (de) 1988-02-17 1988-02-17 Cephalosporinderivate und verfahren zu ihrer herstellung

Publications (1)

Publication Number Publication Date
ZA891162B true ZA891162B (en) 1989-10-25

Family

ID=6347539

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA891162A ZA891162B (en) 1988-02-17 1989-02-15 Cephalosporin derivatives and processes for their preparation

Country Status (23)

Country Link
US (2) US5100887A (fr)
EP (1) EP0329008B1 (fr)
JP (1) JP2509689B2 (fr)
KR (1) KR0140886B1 (fr)
CN (1) CN1043042C (fr)
AT (1) ATE183188T1 (fr)
AU (1) AU613152B2 (fr)
CA (1) CA1339421C (fr)
DD (1) DD283629A5 (fr)
DE (2) DE3804841A1 (fr)
DK (1) DK174730B1 (fr)
DZ (1) DZ1324A1 (fr)
ES (1) ES2136591T3 (fr)
FI (1) FI93458C (fr)
GR (1) GR3031542T3 (fr)
HU (1) HU205121B (fr)
IL (1) IL89303A0 (fr)
MY (1) MY104937A (fr)
NO (1) NO173736C (fr)
NZ (1) NZ227990A (fr)
PT (1) PT89729B (fr)
TN (1) TNSN89016A1 (fr)
ZA (1) ZA891162B (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3809561A1 (de) * 1988-03-22 1989-10-05 Hoechst Ag Ester der 7-(2-(2-aminothiazol-4-yl)-2-(z)- hydroxyiminoacetamido)-3-methoxymethyl-3-cephem-4-carbonsaeure, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zubereitungen
DE3919259A1 (de) * 1989-06-13 1990-12-20 Hoechst Ag Kristalline cephem-saeureadditionssalze und verfahren zu ihrer herstellung
YU48484B (sh) * 1991-05-24 1998-09-18 Hoechst Aktiengesellschaft Kristalne kiselinske adicione soli diastereomerno čistih 1-(2,2-dimetilpropioniloksi)-etilestara 3-cefem-4-karbonske kiseline
DE59209994D1 (de) * 1991-09-07 2004-04-29 Aventis Pharma Gmbh Diastereomer des 3-Cephem-4-carbonsäure-1-(-isopropoxycarbonyloxy)ethylesters und Verfahren zu dessen Herstellung
TW212181B (fr) * 1992-02-14 1993-09-01 Hoechst Ag
ES2117066T3 (es) * 1992-05-21 1998-08-01 Hoechst Ag Procedimiento para la disociacion de esteres profarmacos de cefalosporina para dar acido 7-amino-3-metoximetil-cef-3-em-4-carboxilico.
LT3871B (en) 1993-11-30 1996-04-25 Hoechst Ag Additive crystalline salts of pure diastereomers of 1-cefem-4-carboxylic acid 1-(2,2-dimethyl-propionyloxy)ethyl esters, process for the preparation thereof, pharmaceutical compositions and process for the preparation thereof
DE4418957A1 (de) * 1994-05-31 1995-12-07 Merck Patent Gmbh Cefixim-Zubereitung
SE524569C2 (sv) * 1998-11-20 2004-08-31 Perstorp Ab Förfarande för framställning av en allyloxikarboxylsyra, användning av allyoxikarboxylsyran framställd enligt förfarandet som komponent i oligomera och polymera bindemedel samt 6-allyloxihexansyra framställd enligt förfarandet
AT408226B (de) * 1999-05-05 2001-09-25 Biochemie Gmbh Kristalliner 7-(2-(2-formylaminothiazol-4-yl)-2
AU2003282267A1 (en) * 2002-11-22 2004-06-18 Orchid Chemicals And Pharmaceuticals Ltd An improved process for the preparation of cefpodoxime proxetil
WO2005019227A1 (fr) * 2003-08-22 2005-03-03 Orchid Chemicals & Pharmaceuticals Ltd Procede de preparation d'un antibiotique a base de cephalosporine
JP2010047550A (ja) * 2008-08-25 2010-03-04 Daicel Chem Ind Ltd アルコキシアルカンカルボン酸エステルの製造方法
KR102515013B1 (ko) 2016-02-04 2023-03-30 애플 인크. 무선 레인징에 기초한 전자 디바이스들의 제어 및 정보의 디스플레이

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK154939C (da) * 1974-12-19 1989-06-12 Takeda Chemical Industries Ltd Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf
US4203899A (en) * 1974-12-19 1980-05-20 Takeda Chemical Industries, Ltd. Thiazolylacetamido compounds
US4668783A (en) * 1974-12-19 1987-05-26 Takeda Chemical Industries, Ltd. Thiazolylacetamido cephalosporin compounds
US4298606A (en) * 1974-12-19 1981-11-03 Takeda Chemical Industries, Ltd. Thiazolylacetamido compounds
JPS5760345B2 (fr) * 1974-12-19 1982-12-18 Takeda Chemical Industries Ltd
DE2760123C2 (de) * 1976-01-23 1986-04-30 Roussel-Uclaf, Paris 7-Aminothiazolyl-syn-oxyiminoacetamidocephalosporansäuren, ihre Herstellung und sie enthaltende pharmazeutische Zusammensetzungen
JPS6011713B2 (ja) * 1976-09-08 1985-03-27 武田薬品工業株式会社 セフアロスポリン誘導体およびその製造法
DE2714880A1 (de) * 1977-04-02 1978-10-26 Hoechst Ag Cephemderivate und verfahren zu ihrer herstellung
US4409215A (en) * 1979-11-19 1983-10-11 Fujisawa Pharmaceutical Co., Ltd. 7-Acylamino-3-substituted cephalosporanic acid derivatives and processes for the preparation thereof
FR2476087A1 (fr) * 1980-02-18 1981-08-21 Roussel Uclaf Nouvelles oximes derivees de l'acide 3-alkyloxy ou 3-alkyl-thiomethyl 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
US4486425A (en) * 1980-09-30 1984-12-04 Sankyo Company Limited 7-[2-(2-Aminothiazol-4-yl)-2-(syn)-methoxyiminoacetamido]-3-methoxymethyl-3-cephem-4-carboxylates
JPS5759894A (en) * 1980-09-30 1982-04-10 Sankyo Co Ltd Cephalosporin for oral administration
JPS609757B2 (ja) * 1981-07-16 1985-03-12 三共株式会社 経口用セフアロスポリン化合物
GB8400024D0 (en) * 1984-01-03 1984-02-08 Glaxo Group Ltd Cephalosporin antibiotics
JPH0631259B2 (ja) * 1984-02-17 1994-04-27 三共株式会社 経口用セフアロスポリン化合物
DE3809561A1 (de) * 1988-03-22 1989-10-05 Hoechst Ag Ester der 7-(2-(2-aminothiazol-4-yl)-2-(z)- hydroxyiminoacetamido)-3-methoxymethyl-3-cephem-4-carbonsaeure, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zubereitungen
DE3901405A1 (de) * 1989-01-19 1990-07-26 Hoechst Ag Cephalosporinderivate und verfahren zu ihrer herstellung
US5063224A (en) * 1990-07-09 1991-11-05 Eli Lilly And Company R-cefuroxime axetil

Also Published As

Publication number Publication date
AU3003189A (en) 1989-08-17
TNSN89016A1 (fr) 1991-02-04
DD283629A5 (de) 1990-10-17
EP0329008B1 (fr) 1999-08-11
DK174730B1 (da) 2003-10-06
DZ1324A1 (fr) 2004-09-13
HU205121B (en) 1992-03-30
PT89729A (pt) 1989-10-04
CN1035509A (zh) 1989-09-13
DK72289D0 (da) 1989-02-16
DE58909854D1 (de) 1999-09-16
AU613152B2 (en) 1991-07-25
MY104937A (en) 1994-07-30
CA1339421C (fr) 1997-09-02
JPH01249778A (ja) 1989-10-05
CN1043042C (zh) 1999-04-21
NO173736B (no) 1993-10-18
EP0329008A3 (fr) 1991-08-28
HUT49614A (en) 1989-10-30
ES2136591T3 (es) 1999-12-01
DK72289A (da) 1989-08-18
IL89303A0 (en) 1989-09-10
NO890657L (no) 1989-08-18
US5100887A (en) 1992-03-31
NZ227990A (en) 1990-10-26
FI93458C (fi) 1995-04-10
FI93458B (fi) 1994-12-30
NO890657D0 (no) 1989-02-16
NO173736C (no) 1994-01-26
PT89729B (pt) 1994-03-31
DE3804841A1 (de) 1989-08-31
FI890722A0 (fi) 1989-02-15
USRE34865E (en) 1995-02-21
KR890013028A (ko) 1989-09-20
GR3031542T3 (en) 2000-01-31
FI890722A (fi) 1989-08-18
KR0140886B1 (ko) 1998-06-01
EP0329008A2 (fr) 1989-08-23
ATE183188T1 (de) 1999-08-15
JP2509689B2 (ja) 1996-06-26

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