NO173736C - Analogifremgangsmaate for fremstilling av en terapeutisk aktiv forbindelse bestaaende hovedsaklig av diastereomer (I) av cefalosporinderivater - Google Patents

Analogifremgangsmaate for fremstilling av en terapeutisk aktiv forbindelse bestaaende hovedsaklig av diastereomer (I) av cefalosporinderivater

Info

Publication number
NO173736C
NO173736C NO890657A NO890657A NO173736C NO 173736 C NO173736 C NO 173736C NO 890657 A NO890657 A NO 890657A NO 890657 A NO890657 A NO 890657A NO 173736 C NO173736 C NO 173736C
Authority
NO
Norway
Prior art keywords
diastereomer
preparing
active compound
therapeutically active
consisting mainly
Prior art date
Application number
NO890657A
Other languages
English (en)
Other versions
NO890657D0 (no
NO890657L (no
NO173736B (no
Inventor
Friedhelm Adam
Juergen Blumbach
Walter Duerckheimer
Gerd Fischer
Burghard Mencke
Dieter Isert
Gerhard Seibert
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of NO890657D0 publication Critical patent/NO890657D0/no
Publication of NO890657L publication Critical patent/NO890657L/no
Publication of NO173736B publication Critical patent/NO173736B/no
Publication of NO173736C publication Critical patent/NO173736C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • C07D501/34—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO890657A 1988-02-17 1989-02-16 Analogifremgangsmaate for fremstilling av en terapeutisk aktiv forbindelse bestaaende hovedsaklig av diastereomer (I) av cefalosporinderivater NO173736C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3804841A DE3804841A1 (de) 1988-02-17 1988-02-17 Cephalosporinderivate und verfahren zu ihrer herstellung

Publications (4)

Publication Number Publication Date
NO890657D0 NO890657D0 (no) 1989-02-16
NO890657L NO890657L (no) 1989-08-18
NO173736B NO173736B (no) 1993-10-18
NO173736C true NO173736C (no) 1994-01-26

Family

ID=6347539

Family Applications (1)

Application Number Title Priority Date Filing Date
NO890657A NO173736C (no) 1988-02-17 1989-02-16 Analogifremgangsmaate for fremstilling av en terapeutisk aktiv forbindelse bestaaende hovedsaklig av diastereomer (I) av cefalosporinderivater

Country Status (23)

Country Link
US (2) US5100887A (no)
EP (1) EP0329008B1 (no)
JP (1) JP2509689B2 (no)
KR (1) KR0140886B1 (no)
CN (1) CN1043042C (no)
AT (1) ATE183188T1 (no)
AU (1) AU613152B2 (no)
CA (1) CA1339421C (no)
DD (1) DD283629A5 (no)
DE (2) DE3804841A1 (no)
DK (1) DK174730B1 (no)
DZ (1) DZ1324A1 (no)
ES (1) ES2136591T3 (no)
FI (1) FI93458C (no)
GR (1) GR3031542T3 (no)
HU (1) HU205121B (no)
IL (1) IL89303A0 (no)
MY (1) MY104937A (no)
NO (1) NO173736C (no)
NZ (1) NZ227990A (no)
PT (1) PT89729B (no)
TN (1) TNSN89016A1 (no)
ZA (1) ZA891162B (no)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3809561A1 (de) * 1988-03-22 1989-10-05 Hoechst Ag Ester der 7-(2-(2-aminothiazol-4-yl)-2-(z)- hydroxyiminoacetamido)-3-methoxymethyl-3-cephem-4-carbonsaeure, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zubereitungen
DE3919259A1 (de) * 1989-06-13 1990-12-20 Hoechst Ag Kristalline cephem-saeureadditionssalze und verfahren zu ihrer herstellung
YU48484B (sh) * 1991-05-24 1998-09-18 Hoechst Aktiengesellschaft Kristalne kiselinske adicione soli diastereomerno čistih 1-(2,2-dimetilpropioniloksi)-etilestara 3-cefem-4-karbonske kiseline
EP0531875B1 (de) * 1991-09-07 2004-03-24 Aventis Pharma Deutschland GmbH Diastereomer des 3-Cephem-4-carbonsäure-1-(-isopropoxycarbonyloxy)ethylesters und Verfahren zu dessen Herstellung
TW212181B (no) * 1992-02-14 1993-09-01 Hoechst Ag
ATE164378T1 (de) * 1992-05-21 1998-04-15 Hoechst Ag Verfahren zur spaltung von cephalosporin prodrugestern zu 7-amino-3-methoxymethylceph-3-em-4-carbonsäure
LT3871B (en) 1993-11-30 1996-04-25 Hoechst Ag Additive crystalline salts of pure diastereomers of 1-cefem-4-carboxylic acid 1-(2,2-dimethyl-propionyloxy)ethyl esters, process for the preparation thereof, pharmaceutical compositions and process for the preparation thereof
DE4418957A1 (de) * 1994-05-31 1995-12-07 Merck Patent Gmbh Cefixim-Zubereitung
SE524569C2 (sv) * 1998-11-20 2004-08-31 Perstorp Ab Förfarande för framställning av en allyloxikarboxylsyra, användning av allyoxikarboxylsyran framställd enligt förfarandet som komponent i oligomera och polymera bindemedel samt 6-allyloxihexansyra framställd enligt förfarandet
AT408226B (de) * 1999-05-05 2001-09-25 Biochemie Gmbh Kristalliner 7-(2-(2-formylaminothiazol-4-yl)-2
AU2003282267A1 (en) * 2002-11-22 2004-06-18 Orchid Chemicals And Pharmaceuticals Ltd An improved process for the preparation of cefpodoxime proxetil
WO2005019227A1 (en) * 2003-08-22 2005-03-03 Orchid Chemicals & Pharmaceuticals Ltd Process for the preparation of cephalosporin antibiotic
JP2010047550A (ja) * 2008-08-25 2010-03-04 Daicel Chem Ind Ltd アルコキシアルカンカルボン酸エステルの製造方法
CN114138116A (zh) 2016-02-04 2022-03-04 苹果公司 基于无线测距来控制电子设备和显示信息

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4298606A (en) * 1974-12-19 1981-11-03 Takeda Chemical Industries, Ltd. Thiazolylacetamido compounds
US4668783A (en) * 1974-12-19 1987-05-26 Takeda Chemical Industries, Ltd. Thiazolylacetamido cephalosporin compounds
US4203899A (en) * 1974-12-19 1980-05-20 Takeda Chemical Industries, Ltd. Thiazolylacetamido compounds
JPS5760345B2 (no) * 1974-12-19 1982-12-18 Takeda Chemical Industries Ltd
DK154939C (da) * 1974-12-19 1989-06-12 Takeda Chemical Industries Ltd Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf
DE2760123C2 (de) * 1976-01-23 1986-04-30 Roussel-Uclaf, Paris 7-Aminothiazolyl-syn-oxyiminoacetamidocephalosporansäuren, ihre Herstellung und sie enthaltende pharmazeutische Zusammensetzungen
JPS6011713B2 (ja) * 1976-09-08 1985-03-27 武田薬品工業株式会社 セフアロスポリン誘導体およびその製造法
DE2714880A1 (de) * 1977-04-02 1978-10-26 Hoechst Ag Cephemderivate und verfahren zu ihrer herstellung
US4409215A (en) * 1979-11-19 1983-10-11 Fujisawa Pharmaceutical Co., Ltd. 7-Acylamino-3-substituted cephalosporanic acid derivatives and processes for the preparation thereof
FR2476087A1 (fr) * 1980-02-18 1981-08-21 Roussel Uclaf Nouvelles oximes derivees de l'acide 3-alkyloxy ou 3-alkyl-thiomethyl 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
US4486425A (en) * 1980-09-30 1984-12-04 Sankyo Company Limited 7-[2-(2-Aminothiazol-4-yl)-2-(syn)-methoxyiminoacetamido]-3-methoxymethyl-3-cephem-4-carboxylates
JPS5759894A (en) * 1980-09-30 1982-04-10 Sankyo Co Ltd Cephalosporin for oral administration
JPS609757B2 (ja) * 1981-07-16 1985-03-12 三共株式会社 経口用セフアロスポリン化合物
GB8400024D0 (en) * 1984-01-03 1984-02-08 Glaxo Group Ltd Cephalosporin antibiotics
JPH0631259B2 (ja) * 1984-02-17 1994-04-27 三共株式会社 経口用セフアロスポリン化合物
DE3809561A1 (de) * 1988-03-22 1989-10-05 Hoechst Ag Ester der 7-(2-(2-aminothiazol-4-yl)-2-(z)- hydroxyiminoacetamido)-3-methoxymethyl-3-cephem-4-carbonsaeure, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zubereitungen
DE3901405A1 (de) * 1989-01-19 1990-07-26 Hoechst Ag Cephalosporinderivate und verfahren zu ihrer herstellung
US5063224A (en) * 1990-07-09 1991-11-05 Eli Lilly And Company R-cefuroxime axetil

Also Published As

Publication number Publication date
ES2136591T3 (es) 1999-12-01
NO890657D0 (no) 1989-02-16
DE58909854D1 (de) 1999-09-16
EP0329008A3 (de) 1991-08-28
EP0329008A2 (de) 1989-08-23
JPH01249778A (ja) 1989-10-05
DE3804841A1 (de) 1989-08-31
DK72289A (da) 1989-08-18
FI890722A (fi) 1989-08-18
NO890657L (no) 1989-08-18
US5100887A (en) 1992-03-31
TNSN89016A1 (fr) 1991-02-04
FI93458B (fi) 1994-12-30
ATE183188T1 (de) 1999-08-15
GR3031542T3 (en) 2000-01-31
EP0329008B1 (de) 1999-08-11
CN1035509A (zh) 1989-09-13
ZA891162B (en) 1989-10-25
HUT49614A (en) 1989-10-30
CN1043042C (zh) 1999-04-21
PT89729A (pt) 1989-10-04
KR0140886B1 (ko) 1998-06-01
DD283629A5 (de) 1990-10-17
NZ227990A (en) 1990-10-26
MY104937A (en) 1994-07-30
FI890722A0 (fi) 1989-02-15
AU3003189A (en) 1989-08-17
DZ1324A1 (fr) 2004-09-13
AU613152B2 (en) 1991-07-25
DK174730B1 (da) 2003-10-06
NO173736B (no) 1993-10-18
IL89303A0 (en) 1989-09-10
FI93458C (fi) 1995-04-10
DK72289D0 (da) 1989-02-16
CA1339421C (en) 1997-09-02
USRE34865E (en) 1995-02-21
JP2509689B2 (ja) 1996-06-26
HU205121B (en) 1992-03-30
KR890013028A (ko) 1989-09-20
PT89729B (pt) 1994-03-31

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