ZA878824B - Process for the determination of a specifically bindable substance - Google Patents

Process for the determination of a specifically bindable substance

Info

Publication number
ZA878824B
ZA878824B ZA878824A ZA878824A ZA878824B ZA 878824 B ZA878824 B ZA 878824B ZA 878824 A ZA878824 A ZA 878824A ZA 878824 A ZA878824 A ZA 878824A ZA 878824 B ZA878824 B ZA 878824B
Authority
ZA
South Africa
Prior art keywords
determination
specifically binding
binding substance
specifically bindable
bindable substance
Prior art date
Application number
ZA878824A
Other languages
English (en)
Inventor
Wilhelm Tischer
Tischer Wilhelm
Josef Maier
Maier Josef
Rolf Deeg
Deeg Rolf
Original Assignee
Boehringer Mannheim Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh
Publication of ZA878824B publication Critical patent/ZA878824B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/551—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being inorganic
    • G01N33/552—Glass or silica
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/544—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G01N33/78—Thyroid gland hormones, e.g. T3, T4, TBH, TBG or their receptors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Endocrinology (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Formation And Processing Of Food Products (AREA)
  • Press Drives And Press Lines (AREA)
ZA878824A 1986-11-26 1987-11-25 Process for the determination of a specifically bindable substance ZA878824B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19863640412 DE3640412A1 (de) 1986-11-26 1986-11-26 Verfahren zur bestimmung einer spezifisch bindefaehigen substanz

Publications (1)

Publication Number Publication Date
ZA878824B true ZA878824B (en) 1989-04-26

Family

ID=6314821

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA878824A ZA878824B (en) 1986-11-26 1987-11-25 Process for the determination of a specifically bindable substance

Country Status (13)

Country Link
US (1) US5061640A (ja)
EP (1) EP0269092B1 (ja)
JP (1) JPH0731205B2 (ja)
KR (1) KR910002543B1 (ja)
CN (1) CN1032164C (ja)
AT (1) ATE86743T1 (ja)
AU (1) AU592910B2 (ja)
CA (1) CA1302245C (ja)
DD (1) DD279741A5 (ja)
DE (2) DE3640412A1 (ja)
ES (1) ES2054648T3 (ja)
GR (1) GR3007910T3 (ja)
ZA (1) ZA878824B (ja)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3725504A1 (de) * 1987-07-31 1989-02-09 Thraenhart Olaf Priv Doz Dr Verfahren und vorrichtung zum nachweis von antikoerpern und antigenen
US5268306A (en) * 1988-02-29 1993-12-07 Boehringer Mannheim Gmbh Preparation of a solid phase matrix containing a bound specific binding pair
DE3806431A1 (de) * 1988-02-29 1989-09-07 Boehringer Mannheim Gmbh Verfahren zur herstellung einer festphasenmatrix
IE64286B1 (en) * 1988-05-25 1995-07-26 Boehringer Mannheim Gmbh Process for the determination of an immunologically detectable substance and a suitable vessel therefor
US5362624A (en) * 1988-05-25 1994-11-08 Boehringer Mannheim Gmbh Process for the determination of an immunologically detectable substance and a suitable reaction vessel therefor
DE3901638C2 (de) * 1988-05-25 1999-03-25 Roche Diagnostics Gmbh Verfahren zur Bestimmung einer immunologisch nachweisbaren Substanz und dazu geeignetes Reaktionsgefäß
US5888728A (en) 1988-10-17 1999-03-30 Molecular Devices Corporation Hapten derivatized capture membrane and diagnostic assays using such membrane
DE3842700A1 (de) * 1988-12-19 1990-06-21 Boehringer Mannheim Gmbh Verfahren zur proteinimmobilisierung an einer festphase, so hergestellte protein tragende festphase sowie deren verwendung
US6333397B1 (en) 1989-04-25 2001-12-25 Roche Diagnostics Gmbh Monoclonal antibodies to troponin T and their production
DE3922873A1 (de) * 1989-04-25 1990-10-31 Boehringer Mannheim Gmbh Spezifische antikoerper gegen troponin t, ihre herstellung und verwendung in einem reagenz zur bestimmung von hermuskelnekrosen
DE3915135A1 (de) * 1989-05-09 1990-11-15 Boehringer Mannheim Gmbh Verfahren zum nachweis spezifisch bindefaehiger substanzen in koerperfluessigkeiten
US5270193A (en) * 1989-10-27 1993-12-14 E. I. Dupont De Nemours And Company Immobilization of biomolecules on perfluorocarbon surfaces
GB8927230D0 (en) * 1989-12-01 1990-01-31 Unilever Plc Reagents
DE3942999C2 (de) * 1989-12-27 1997-12-18 Progen Biotechnik Gmbh Verfahren zum Nachweis von malignen Erkrankungen
DE4024544A1 (de) * 1990-08-02 1992-02-06 Boehringer Mannheim Gmbh Analyseelement und verfahren zu seiner herstellung
DE4025726A1 (de) 1990-08-14 1992-02-20 Boehringer Mannheim Gmbh Bestimmung von biogenen aminen
WO1992003732A2 (en) * 1990-08-28 1992-03-05 Bioprobe International, Inc. Compositions and methods for enhanced binding in biological assays
JPH04363659A (ja) * 1991-06-10 1992-12-16 Smithkline Beckman Corp ビタミンｂ１２の分析
WO1992022816A1 (en) * 1991-06-11 1992-12-23 Csl Limited Solid phase immunoassay
DE4209215A1 (de) 1991-07-04 1993-01-07 Boehringer Mannheim Gmbh Hcv peptidantigene und verfahren zur bestimmung von hcv
DE4202850A1 (de) * 1992-01-31 1993-08-05 Boehringer Mannheim Gmbh Analysenelement fuer immunoassays
DE4240980A1 (de) * 1992-08-07 1994-02-10 Boehringer Mannheim Gmbh HCV Peptidantigene und Verfahren zur Bestimmung von HCV
DE4312399A1 (de) * 1993-04-16 1994-10-20 Boehringer Mannheim Gmbh Verfahren zur Bestimmung der Bindung eines Transkriptionsfaktors an eine Nukleinsäure
DE4313975A1 (de) * 1993-04-28 1994-11-03 Cytech Biomedical Inc Immunisierungsmittel und Affinitätschromatographie-Trägermaterial
DE4343479A1 (de) * 1993-12-21 1995-06-22 Boehringer Mannheim Gmbh Acylierte Proteinaggregate und deren Verwendung zur Entstörung von Immunoassays
DE4343480A1 (de) * 1993-12-21 1995-07-06 Boehringer Mannheim Gmbh Acylierte Proteinaggregate und deren Verwendung zur Signalsteigerung in einem Immunoassay zum Nachweis von Antikörpern
DE19637718A1 (de) 1996-04-01 1997-10-02 Boehringer Mannheim Gmbh Rekombinante inaktive Core-Streptavidin Mutanten
DE19724787A1 (de) * 1997-06-06 1998-12-10 Biotez Berlin Buch Gmbh Bioche Streptavidin/Avidin beschichtete Oberflächen
US6033918A (en) * 1997-11-10 2000-03-07 Bayer Corporation Method and device for the detection of analyte in a fluid sample
DE19924643B4 (de) * 1999-05-28 2017-02-23 Roche Diagnostics Gmbh Verfahren zur Herstellung von Protein-beladenen Mikropartikeln
DE50207516D1 (de) * 2001-08-10 2006-08-24 Roche Diagnostics Gmbh Verfahren zur herstellung von protein-beladenen mikropartikeln
JP5476376B2 (ja) * 2008-07-16 2014-04-23 ラジオメーター・メディカル・アー・ペー・エス 高性能固相
GB201105828D0 (en) 2011-04-06 2011-05-18 Vivacta Ltd A device for detecting an analyte
GB201121269D0 (en) 2011-12-12 2012-01-25 Vivacta Ltd A method forblood measurement
JP5717658B2 (ja) * 2012-01-13 2015-05-13 シスメックス株式会社 副腎皮質刺激ホルモンの検出方法および吸着剤
WO2016151558A1 (en) 2015-03-25 2016-09-29 Alexion Pharmaceuticals, Inc. A method for measuring the protease activity of factor d of the alternative complement pathway
WO2016151557A1 (en) 2015-03-25 2016-09-29 Alexion Pharmaceuticals, Inc. A method for measuring the protease activity of c5 convertase of the alternative complement pathway
CN109154616B (zh) 2016-05-31 2022-07-12 豪夫迈·罗氏有限公司 用于病毒抗原的血清学检测的方法
JP7044721B2 (ja) 2016-05-31 2022-03-30 エフ．ホフマン－ラ ロシュ アーゲー Ｈｃｖコア抗原の迅速な検出のための前処理法
EP3577460B1 (en) 2017-02-02 2021-01-20 Roche Diagnostics GmbH Immunoassay using at least two pegylated analyte-specific binding agents
ES2961462T3 (es) 2017-07-27 2024-03-12 Roche Diagnostics Gmbh Proteína de fusión multiepítopo de un antígeno del VHC y usos de la misma
CN113030456A (zh) * 2021-04-02 2021-06-25 山东康华生物医疗科技股份有限公司 一种抗环瓜氨酸肽抗体的检测试纸条、检测卡及试剂盒

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4006059A (en) * 1974-07-29 1977-02-01 Purdue Research Foundation Hydrophobic noncovalent binding of proteins to support materials
US3966580A (en) * 1974-09-16 1976-06-29 The University Of Utah Novel protein-immobilizing hydrophobic polymeric membrane, process for producing same and apparatus employing same
US4069352A (en) * 1976-07-02 1978-01-17 Baxter Travenol Laboratories, Inc. Immunoadsorbent polymeric material and method of making same
US4210418A (en) * 1976-08-30 1980-07-01 Mallinckrodt, Inc. Container for immunochemical and enzymatical determinations or procedures
AU533026B2 (en) * 1979-10-26 1983-10-27 Dynasciences Corp. Passively adsorbing immuno-reactive haptens to solid phases
SE8003732L (sv) * 1980-05-19 1981-11-20 Pharmacia Diagnostics Ab Sett vid bestemningsmetoder involverande biospecifika affinitetsreaktioner
DE3116491A1 (de) * 1981-04-25 1982-11-11 Basf Ag, 6700 Ludwigshafen "thermoplastische formmassen"
JPS5861466A (ja) * 1981-10-08 1983-04-12 Yatoron:Kk 血清学的凝集反応による測定方法
US4606855A (en) * 1982-07-26 1986-08-19 Mex Research Associates C/O Leon Reimer Monoclonal antibody to digoxin
US4572901A (en) * 1983-06-23 1986-02-25 Children's Hospital Medical Center Of Northern California Method and composition for protein immobilization
EP0142193A1 (en) * 1983-10-22 1985-05-22 Akzo N.V. Preparation of immunogens consisting of antigens and/or antigenic determinants bound to glycoside-containing carriers
JPS62132172A (ja) * 1985-12-04 1987-06-15 Shionogi & Co Ltd 固相化抗体およびその製造方法
US4808530A (en) * 1986-09-05 1989-02-28 The Ohio State University Protein immobilization by adsorption of a hydrophobic amidine protein derivative to a hydrophobic surface

Also Published As

Publication number Publication date
DD279741A5 (de) 1990-06-13
ES2054648T3 (es) 1994-08-16
CN87107982A (zh) 1988-06-15
KR890002227A (ko) 1989-04-10
DE3784638D1 (de) 1993-04-15
CN1032164C (zh) 1996-06-26
AU8169587A (en) 1988-06-02
US5061640A (en) 1991-10-29
ATE86743T1 (de) 1993-03-15
KR910002543B1 (ko) 1991-04-23
JPH0731205B2 (ja) 1995-04-10
EP0269092A2 (de) 1988-06-01
CA1302245C (en) 1992-06-02
EP0269092A3 (en) 1990-01-24
AU592910B2 (en) 1990-01-25
GR3007910T3 (ja) 1993-08-31
JPS63142268A (ja) 1988-06-14
EP0269092B1 (de) 1993-03-10
DE3640412A1 (de) 1988-06-09

Similar Documents

Publication Publication Date Title
ZA878824B (en) Process for the determination of a specifically bindable substance
DE3380697D1 (en) Monoclonal antibody
GB9206422D0 (en) Antibody preparation
AU2843889A (en) Antigen antibody conjugate
HUT50988A (en) Method for obtaining polimer derivates of immunoglobuline g for compensating factors disturbing immunotests
ZA897689B (en) Process for the determination of a specifically bindable substance
CA2056279A1 (en) Cell-free receptor binding assays, the production and use thereof
AU8172094A (en) Synthetic HTLV-III peptides, compositions and uses thereof
AU585253B2 (en) Carrier material for use in immune determinations
AU8185494A (en) Diagnostic assay for alzheimer's disease
WO1995007466A3 (en) Biotin-analog conjugated antibodies for positive cell selection and release
EP0109434A4 (en) IN VITRO DIAGNOSTICS METHODS USING MONOCLONAL ANTIBODIES AGAINST PROTEINS OF CONNECTIVE TISSUES.
EP0478689A4 (en) Human monoclonal antibodies to hiv-1 mn? gp 120
EP0635016A4 (en) BENZODIAZEPINE DERIVATIVES AND PROTEIN AND POLYPEPTIDE CONJUGATES OF SUCH DERIVATIVES.
AU8944291A (en) Immunoassay for the determination of anti-hiv antibodies in human samples
CA2106563A1 (en) Cocaine derivatives and protein and polypeptide cocaine derivative conjugates and labels
ATE90790T1 (de) Verfahren zur herstellung einer festphasenmatrix.
EP0269677A4 (en) ANALYZES AND ANTIBODIES OF N - i PROTEINS (myc).
AU1042488A (en) Bilirubin antigen, monoclonal antibody therefor, process for their preparation, and their use
AU3024889A (en) Immunoassay for herpes virus antigens bound to solid support
CA2004387A1 (en) Cyclosporine binding protein and use in an assay for biologically-active cyclosporine
WO1996040664A3 (en) Preparation of immunogens and other conjugates of drugs
DE3468324D1 (en) Specific antibody to the native form of 2'5'-oligonucleotides, the method of preparation and the use as reagents in immunoassays or for binding 2'5'-oligonucleotides in biological systems
JPS5328164A (en) Maleimide derivatives
EP0309992A3 (en) Iron colloid-labeled antibody, preparation thereof and histochemical detection thereby