ZA878306B - Therapeutic agents - Google Patents

Therapeutic agents

Info

Publication number
ZA878306B
ZA878306B ZA878306A ZA878306A ZA878306B ZA 878306 B ZA878306 B ZA 878306B ZA 878306 A ZA878306 A ZA 878306A ZA 878306 A ZA878306 A ZA 878306A ZA 878306 B ZA878306 B ZA 878306B
Authority
ZA
South Africa
Prior art keywords
lower alkyl
therapeutic agents
halo
trifluoromethyl
novel
Prior art date
Application number
ZA878306A
Other languages
English (en)
Inventor
Victor Davies Roy
Original Assignee
The Boots Company Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Boots Company Plc filed Critical The Boots Company Plc
Publication of ZA878306B publication Critical patent/ZA878306B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pyridine Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Liquid Crystal Substances (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
ZA878306A 1986-11-20 1987-11-05 Therapeutic agents ZA878306B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB868627698A GB8627698D0 (en) 1986-11-20 1986-11-20 Therapeutic agents

Publications (1)

Publication Number Publication Date
ZA878306B true ZA878306B (en) 1988-05-02

Family

ID=10607612

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA878306A ZA878306B (en) 1986-11-20 1987-11-05 Therapeutic agents

Country Status (24)

Country Link
US (1) US4877793A (fi)
EP (1) EP0269295B1 (fi)
JP (1) JPS63141984A (fi)
KR (1) KR880006247A (fi)
CN (1) CN1019491B (fi)
AT (1) ATE64736T1 (fi)
AU (1) AU599721B2 (fi)
DD (1) DD282690A5 (fi)
DE (1) DE3771039D1 (fi)
DK (1) DK599887A (fi)
ES (1) ES2038188T3 (fi)
FI (1) FI875020A (fi)
GB (1) GB8627698D0 (fi)
GR (1) GR3002500T3 (fi)
HU (1) HU198060B (fi)
IL (1) IL84505A (fi)
JO (1) JO1520B1 (fi)
MX (1) MX9428A (fi)
NO (1) NO874834L (fi)
NZ (1) NZ222554A (fi)
PH (1) PH23293A (fi)
PL (1) PL149617B1 (fi)
PT (1) PT86115B (fi)
ZA (1) ZA878306B (fi)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8726950D0 (en) * 1987-11-18 1987-12-23 Boots Co Plc Chemical process
NZ230711A (en) * 1988-09-23 1990-10-26 Ortho Pharma Corp Substituted thienopyrans as antihypertensive agents
ZA903588B (en) * 1989-05-16 1991-02-27 Merrell Dow Pharma Excitatory amino acid antagonists
US5026700A (en) * 1989-05-16 1991-06-25 Merrell Dow Pharmaceuticals Certain quinolines and thienopyridines as excitatory amino acid antagonists
US5219864A (en) * 1991-03-12 1993-06-15 Kyowa Hakko Kogyo Co., Ltd. Thienopyridine derivatives
JP2699794B2 (ja) * 1992-03-12 1998-01-19 三菱化学株式会社 チエノ〔３，２−ｂ〕ピリジン誘導体
DE4227747A1 (de) * 1992-08-21 1994-02-24 Basf Ag Heteroaromatisch kondensierte Hydroxypyridoncarbonsäureamide, deren Herstellung und Verwendung
WO2000007595A1 (en) * 1998-08-03 2000-02-17 Basf Corporation Pyridinones for the treatment of sexual dysfunction
US6562838B2 (en) * 2001-01-26 2003-05-13 R. T. Alamo Ventures I, L.L.C. Treatment of cardiovascular disease with quinolinone enantiomers
US6458804B1 (en) * 2001-01-26 2002-10-01 R.T. Alamo Venturesi, Llc Methods for the treatment of central nervous system disorders in certain patient groups
US6451813B1 (en) 2001-01-26 2002-09-17 R. T. Alamo Ventures I, Llc Treatment of gastroparesis in certain patient groups
US8329924B2 (en) 2001-06-11 2012-12-11 Vertex Pharmaceuticals (Canada) Incorporated Compounds and methods for the treatment or prevention of Flavivirus infections
PT1401825E (pt) 2001-06-11 2009-10-23 Virochem Pharma Inc Compostos e métodos para o tratamento ou para a prevenção de infecções com flavivírus
WO2003020728A1 (en) 2001-08-30 2003-03-13 Pharmacia & Upjohn Company 4-THIOXO-4,7-DIHYDRO-THIENO[2,3-b]PYRIDINE-5-CARBOTHIOAMIDES AS ANTIVIRAL AGENTS
AR038294A1 (es) * 2002-01-14 2005-01-12 Upjohn Co Oxotieno(3,2-b)piridincarboxamidas como agentes antivirales
AR038117A1 (es) 2002-01-14 2004-12-29 Upjohn Co Agentes antivirales derivados de la 4- oxo-4,7 -dihidrofuro [2,3-b]piridin-5-carboxamida
AR038118A1 (es) 2002-01-14 2004-12-29 Upjohn Co Compuestos derivados de la bencinamida del acido 7-oxo-4,7-dihidrotien[2,3-b[piridin-6-carboxilico 3-sustituido que son utiles como antivirales
US7402608B2 (en) 2002-12-10 2008-07-22 Virochem Pharma Inc. Compounds and methods for the treatment or prevention of Flavivirus infections
CA2607359C (en) 2005-05-13 2011-08-09 Virochem Pharma Inc. Compounds and methods for the treatment or prevention of flavivirus infections
JP2008093872A (ja) * 2006-10-09 2008-04-24 Kouritsu Kogyo:Kk 表示装置
BRPI0718915A2 (pt) 2006-11-15 2013-12-03 Virochem Pharma Inc Análogos de tiofeno para o tratamento ou prevenção de infecções por flavivírus
WO2009135580A1 (en) * 2008-05-05 2009-11-12 Merck Patent Gmbh Thienopyridone derivatives as amp-activated protein kinase (ampk) activators
EP2702085A1 (en) * 2011-04-27 2014-03-05 Basf Se Semiconductor materials based on dithienopyridone copolymers
PE20191817A1 (es) * 2017-05-11 2019-12-27 Bristol Myers Squibb Co Tienopiridinas y benzotiofenos utiles como inhibidores de cinasa 4 asociada al receptor de interleucina 1 (irak4)

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3903095A (en) * 1972-02-18 1975-09-02 Merck & Co Inc Certain substituted-thieno{8 3,2-c{9 -pyridines
US3997545A (en) * 1973-07-23 1976-12-14 Takeda Chemical Industries, Ltd. Thienopyridine-carboxylic acid derivatives
NZ193167A (en) * 1979-03-27 1984-08-24 Boots Co Plc Quinoline derivatives and pharmaceutical compositions
JPS5742690A (en) * 1980-08-28 1982-03-10 Kanebo Ltd Thieno 3,2-b pyridinecarboxylic acid derivative
IE51542B1 (en) * 1980-09-26 1987-01-07 Boots Co Ltd Therapeutic agents
EP0126970A3 (en) * 1983-04-27 1985-11-06 Beecham Group Plc Anxiolytic and anti-depressant thienopyridine derivatives
PT79031B (en) * 1983-08-20 1986-08-22 Boots Co Plc Therapeutic agents
EP0149519B1 (en) * 1984-01-13 1990-06-27 The Boots Company PLC Use of quinolones for the manufacture of a composition for the treatment of heart failure.
GB2161524B (en) * 1984-07-13 1988-01-06 Pandrol Ltd Improvements in or relating to rail pads and rail assemblies including such pads
EP0172004B1 (en) * 1984-08-15 1990-03-21 The Boots Company PLC Quinolinones, process for their preparation and pharmaceutical compositions containing them
GB8515209D0 (en) * 1985-06-15 1985-07-17 Boots Co Plc Therapeutic agents
GB8515207D0 (en) * 1985-06-15 1985-07-17 Boots Co Plc Therapeutic agents

Also Published As

Publication number Publication date
JO1520B1 (en) 1989-01-25
FI875020A0 (fi) 1987-11-13
ES2038188T3 (es) 1993-07-16
DD282690A5 (de) 1990-09-19
AU8144087A (en) 1988-05-26
ATE64736T1 (de) 1991-07-15
EP0269295B1 (en) 1991-06-26
NO874834L (no) 1988-05-24
PT86115B (pt) 1990-08-31
AU599721B2 (en) 1990-07-26
PL268925A1 (en) 1988-09-01
KR880006247A (ko) 1988-07-22
DE3771039D1 (de) 1991-08-01
NO874834D0 (no) 1987-11-19
PL149617B1 (en) 1990-03-31
DK599887D0 (da) 1987-11-16
NZ222554A (en) 1989-08-29
GB8627698D0 (en) 1986-12-17
HUT47289A (en) 1989-02-28
HU198060B (en) 1989-07-28
US4877793A (en) 1989-10-31
CN87107975A (zh) 1988-06-01
IL84505A (en) 1990-12-23
PT86115A (en) 1987-12-01
EP0269295A1 (en) 1988-06-01
PH23293A (en) 1989-06-30
CN1019491B (zh) 1992-12-16
DK599887A (da) 1988-05-21
MX9428A (es) 1993-10-01
GR3002500T3 (en) 1992-12-30
JPS63141984A (ja) 1988-06-14
FI875020A (fi) 1988-05-21

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