ZA875295B - Novel peptides - Google Patents

Novel peptides

Info

Publication number
ZA875295B
ZA875295B ZA875295A ZA875295A ZA875295B ZA 875295 B ZA875295 B ZA 875295B ZA 875295 A ZA875295 A ZA 875295A ZA 875295 A ZA875295 A ZA 875295A ZA 875295 B ZA875295 B ZA 875295B
Authority
ZA
South Africa
Prior art keywords
amino acid
solutions
insulin
asn
substituted
Prior art date
Application number
ZA875295A
Other languages
English (en)
Inventor
Markussen Jan
Norris Kjeld
Langkjaer Liselotte
Original Assignee
Novo Industri A/S.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8123250&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA875295(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novo Industri A/S. filed Critical Novo Industri A/S.
Publication of ZA875295B publication Critical patent/ZA875295B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Endocrinology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Obesity (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Emergency Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA875295A 1986-07-21 1987-07-20 Novel peptides ZA875295B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK347086A DK347086D0 (da) 1986-07-21 1986-07-21 Novel peptides

Publications (1)

Publication Number Publication Date
ZA875295B true ZA875295B (en) 1988-01-21

Family

ID=8123250

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA875295A ZA875295B (en) 1986-07-21 1987-07-20 Novel peptides

Country Status (20)

Country Link
EP (1) EP0254516B1 (fr)
JP (1) JPS6399096A (fr)
KR (1) KR880001701A (fr)
CN (1) CN87104988A (fr)
AT (1) ATE99699T1 (fr)
AU (1) AU612324B2 (fr)
DD (1) DD273839A5 (fr)
DE (2) DE10075024I1 (fr)
DK (1) DK347086D0 (fr)
ES (1) ES2061504T3 (fr)
FI (1) FI873185A (fr)
HU (1) HU203371B (fr)
IL (1) IL83243A (fr)
MY (1) MY102873A (fr)
NL (1) NL300018I1 (fr)
NO (1) NO170978C (fr)
NZ (1) NZ221130A (fr)
PT (1) PT85355B (fr)
YU (1) YU135387A (fr)
ZA (1) ZA875295B (fr)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0280534B1 (fr) * 1987-02-25 1993-04-21 Novo Nordisk A/S Nouveaux dérivés de l'insuline
DK336188D0 (da) * 1988-06-20 1988-06-20 Nordisk Gentofte Propeptider
EP0425482B1 (fr) * 1988-07-20 1993-08-18 Novo Nordisk A/S Analogues d'insuline humaine et preparations les contenant
DE3827533A1 (de) * 1988-08-13 1990-02-15 Hoechst Ag Pharmazeutische zubereitung zur behandlung des diabetes mellitus
DE3837825A1 (de) * 1988-11-08 1990-05-10 Hoechst Ag Neue insulinderivate, ihre verwendung und eine sie enthaltende pharmazeutische zubereitung
WO1990007522A1 (fr) * 1988-12-23 1990-07-12 Novo Nordisk A/S Analogues d'insuline humaine
US5716927A (en) * 1988-12-23 1998-02-10 Novo Nordisk A/S Insulin analogs having a modified B-chain
US5514646A (en) * 1989-02-09 1996-05-07 Chance; Ronald E. Insulin analogs modified at position 29 of the B chain
DK134189D0 (da) * 1989-03-20 1989-03-20 Nordisk Gentofte Insulinforbindelser
DE3936876A1 (de) * 1989-11-06 1991-05-23 Hoechst Ag Neue insulinderivate, verfahren zu deren herstellung, ihre verwendung und eine sie enthaltende pharmazeutische zubereitung
US5474978A (en) * 1994-06-16 1995-12-12 Eli Lilly And Company Insulin analog formulations
US5693609A (en) * 1994-11-17 1997-12-02 Eli Lilly And Company Acylated insulin analogs
US7316999B2 (en) 2000-06-02 2008-01-08 Novo Nordisk A/S Glucose dependent release of insulin from glucose sensing insulin derivatives
DE10114178A1 (de) 2001-03-23 2002-10-10 Aventis Pharma Gmbh Zinkfreie und zinkarme Insulinzubereitungen mit verbesserter Stabilität
BR0213583A (pt) 2001-11-19 2004-08-24 Novo Nordisk As Processo para preparar um composto de insulina, e, composto de insulina
GB0206792D0 (en) 2002-03-22 2002-05-01 Leuven K U Res & Dev Normoglycemia
DE10227232A1 (de) 2002-06-18 2004-01-15 Aventis Pharma Deutschland Gmbh Saure Insulinzubereitungen mit verbesserter Stabilität
PL1641616T3 (pl) 2003-06-27 2011-09-30 Novo Nordisk As Wysoce wilgocioszczelny pojemnik dla medycznych mieszanin ciekłych
CN1898087A (zh) 2003-12-22 2007-01-17 诺沃挪第克公司 用于储存药物液体的透明、柔性、不可渗透的塑料容器
CA2552043A1 (fr) 2004-01-21 2005-08-04 Novo Nordisk A/S Conjugaison de peptides induite par la transglutaminase
DE102006031962A1 (de) 2006-07-11 2008-01-17 Sanofi-Aventis Deutschland Gmbh Amidiertes Insulin Glargin
DE102006031955A1 (de) * 2006-07-11 2008-01-17 Sanofi-Aventis Deutschland Gmbh Verfahren zur Herstellung von Insulinanaloga mit dibasischem B-Kettenende
WO2008049711A1 (fr) 2006-10-27 2008-05-02 Novo Nordisk A/S Insuline à peptide ajouté
NZ586589A (en) 2008-01-09 2012-04-27 Sanofi Aventis Deutschland Novel insulin analogues having an extremely delayed time-action profile
BRPI0907371A2 (pt) 2008-01-09 2015-11-24 Sanofi Aventis Deutschland derivados de insulina com um perfil de tempo-ação muito retardado
EP2910571B1 (fr) 2008-03-18 2016-10-05 Novo Nordisk A/S Analogues de l'insuline acylés, stabilisés à la protéase
TWI451876B (zh) 2008-06-13 2014-09-11 Lilly Co Eli 聚乙二醇化之離脯胰島素化合物
BRPI0823004B8 (pt) 2008-08-07 2021-05-25 Biocon Ltd processo para preparação de compostos de insulina
DK2349324T3 (en) 2008-10-17 2017-12-11 Sanofi Aventis Deutschland COMBINATION OF AN INSULIN AND A GLP-1 AGONIST
US20120241356A1 (en) * 2009-07-06 2012-09-27 Sanofi-Aventis Deutschland Gmbh Heat- and vibration-stable insulin preparations
JP5973918B2 (ja) 2009-11-13 2016-08-23 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング Ｇｌｐ−１アゴニスト及びメチオニンを含む薬学的組成物
KR101836070B1 (ko) 2009-11-13 2018-03-09 사노피-아벤티스 도이칠란트 게엠베하 Ｇｌｐ－１ 작용제, 인슐린 및 메티오닌을 포함하는 약제학적 조성물
EP2359843A1 (fr) 2010-01-21 2011-08-24 Sanofi Composition pharmaceutique pour le traitement d'un syndrome métabolique
TW201141513A (en) 2010-04-14 2011-12-01 Sanofi Aventis Insulin-siRNA conjugates
PT2611458T (pt) 2010-08-30 2016-12-16 Sanofi Aventis Deutschland Utilização de ave0010 para o fabrico de um medicamento para o tratamento da diabetes mellitus tipo 2
US9821032B2 (en) 2011-05-13 2017-11-21 Sanofi-Aventis Deutschland Gmbh Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin
EP2548570A1 (fr) 2011-07-19 2013-01-23 Sanofi Composition pharmaceutique pour le traitement d'un syndrome métabolique
CN108079281A (zh) 2011-08-29 2018-05-29 赛诺菲-安万特德国有限公司 用于2型糖尿病患者中的血糖控制的药物组合
AR087744A1 (es) 2011-09-01 2014-04-16 Sanofi Aventis Deutschland Composicion farmaceutica para uso en el tratamiento de una enfermedad neurodegenerativa
CA2870313A1 (fr) 2012-04-11 2013-10-17 Novo Nordisk A/S Formulations a base d'insuline
WO2015196174A1 (fr) 2014-06-20 2015-12-23 Greene Howard E Dispositifs et procédés d'administration de perfusion
CN107206058A (zh) 2014-12-12 2017-09-26 赛诺菲-安万特德国有限公司 甘精胰岛素/利西拉来固定比率配制剂
TWI748945B (zh) 2015-03-13 2021-12-11 德商賽諾菲阿凡提斯德意志有限公司 第２型糖尿病病患治療
TW201705975A (zh) 2015-03-18 2017-02-16 賽諾菲阿凡提斯德意志有限公司 第２型糖尿病病患之治療
MX2019006463A (es) 2016-12-16 2019-08-14 Novo Nordisk As Composiciones farmaceuticas que contienen insulina.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3033127A1 (de) * 1980-09-03 1982-04-08 Hoechst Ag, 6000 Frankfurt Neue analoga des insulins
DE3327709A1 (de) * 1983-07-29 1985-02-07 Hoechst Ag, 6230 Frankfurt Insulin-derivat-kristallsuspensionen, verfahren zu deren herstellung und deren verwendung
DE3333640A1 (de) * 1983-09-17 1985-04-25 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von insulin-derivaten, deren b-kette c-terminal verlaengert ist, neue basisch modifizierte insulin-derivate diese enthaltende mittel und ihre verwendung
DK113585D0 (da) * 1985-03-12 1985-03-12 Novo Industri As Nye peptider
DK119785D0 (da) * 1985-03-15 1985-03-15 Nordisk Gentofte Insulinpraeparat

Also Published As

Publication number Publication date
NO170978C (no) 1993-01-06
HU203371B (en) 1991-07-29
EP0254516A3 (en) 1990-06-27
YU135387A (en) 1988-10-31
DE10075024I1 (de) 2000-11-09
NL300018I1 (nl) 2000-11-01
NZ221130A (en) 1990-08-28
KR880001701A (ko) 1988-04-26
CN87104988A (zh) 1988-03-02
IL83243A0 (en) 1987-12-31
NO873018D0 (no) 1987-07-20
JPS6399096A (ja) 1988-04-30
NO873018L (no) 1988-01-22
FI873185A0 (fi) 1987-07-20
ATE99699T1 (de) 1994-01-15
EP0254516A2 (fr) 1988-01-27
DE3788684D1 (de) 1994-02-17
PT85355A (en) 1987-08-01
MY102873A (en) 1993-03-31
ES2061504T3 (es) 1994-12-16
DD273839A5 (de) 1989-11-29
DE3788684T2 (de) 1994-05-19
AU612324B2 (en) 1991-07-11
DK347086D0 (da) 1986-07-21
PT85355B (pt) 1990-04-30
EP0254516B1 (fr) 1994-01-05
NO170978B (no) 1992-09-28
AU7591687A (en) 1988-01-28
IL83243A (en) 1993-01-14
FI873185A (fi) 1988-01-22
HUT45271A (en) 1988-06-28

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