ZA874945B - Carbamate or urea derivatives,their preparation and pharmaceutical compositions comprising them - Google Patents

Carbamate or urea derivatives,their preparation and pharmaceutical compositions comprising them

Info

Publication number
ZA874945B
ZA874945B ZA874945A ZA874945A ZA874945B ZA 874945 B ZA874945 B ZA 874945B ZA 874945 A ZA874945 A ZA 874945A ZA 874945 A ZA874945 A ZA 874945A ZA 874945 B ZA874945 B ZA 874945B
Authority
ZA
South Africa
Prior art keywords
group
halogen atoms
carbamate
methyl
alkyl
Prior art date
Application number
ZA874945A
Other languages
English (en)
Inventor
Nigel Beeley
Beeley Nigel
Gerard Cremer
Cremer Gerard
Original Assignee
Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo filed Critical Synthelabo
Publication of ZA874945B publication Critical patent/ZA874945B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/39—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
    • C07C323/40—Y being a hydrogen or a carbon atom
    • C07C323/41—Y being a hydrogen or an acyclic carbon atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/14—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
    • C07C319/20—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides by reactions not involving the formation of sulfide groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Emergency Medicine (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Epidemiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Steroid Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Medicinal Preparation (AREA)
ZA874945A 1986-07-08 1987-07-07 Carbamate or urea derivatives,their preparation and pharmaceutical compositions comprising them ZA874945B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8609887A FR2601363B1 (fr) 1986-07-08 1986-07-08 (dimethylamino)-2 ethyl) ((((methylthio)-2 phenyl) (phenylmethyl)amino)-2 oxo-2 ethyl) carbamates ou urees, leur preparation et leur application en therapeutique.

Publications (1)

Publication Number Publication Date
ZA874945B true ZA874945B (en) 1988-02-24

Family

ID=9337176

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA874945A ZA874945B (en) 1986-07-08 1987-07-07 Carbamate or urea derivatives,their preparation and pharmaceutical compositions comprising them

Country Status (19)

Country Link
US (1) US4840967A (de)
EP (1) EP0252810B1 (de)
JP (1) JPS6323856A (de)
KR (1) KR880001587A (de)
AT (1) ATE62669T1 (de)
AU (1) AU595340B2 (de)
CA (1) CA1277330C (de)
CS (1) CS357891A3 (de)
DE (1) DE3769384D1 (de)
DK (1) DK349287A (de)
FI (1) FI85583C (de)
FR (1) FR2601363B1 (de)
GR (1) GR3002081T3 (de)
HU (1) HU196169B (de)
IL (1) IL83092A (de)
NO (1) NO164593C (de)
NZ (1) NZ220987A (de)
PT (1) PT85280B (de)
ZA (1) ZA874945B (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2641279B1 (fr) * 1989-01-03 1991-02-22 Synthelabo Derives de n-(amino-2 ethyl) n-(((methylthio-2 phenyl) (phenylmethyl)amino)-2 oxo ethyl)amides et carbamates, leur preparation et leur application en therapeutique
JPH02290464A (ja) * 1989-04-28 1990-11-30 Takagi Ind Co Ltd 瞬間湯沸器
EP0903341A1 (de) * 1997-07-22 1999-03-24 Akzo Nobel N.V. Ortho-Mercaptoanilinverbindungen
JP2001501979A (ja) 1998-01-21 2001-02-13 ザイモジェネティクス，インコーポレイティド カルシトニン擬態物としてのジアルキルウレア
AU2002359922A1 (en) * 2001-12-27 2003-07-15 Taisho Pharmaceutical Co., Ltd. Carboxylic acid derivative
FR2885129B1 (fr) * 2005-04-29 2007-06-15 Proskelia Sas Nouveaux derives de l'ureee substituee parun thiazole ou benzothiazole, leur procede de preparation, leur application a titre de medicaments, les compositions pharmaceutiques les renfermant et utilisation.
JP2010512417A (ja) * 2006-12-11 2010-04-22 ワイス エルエルシー イオンチャネルモジュレータ−
US8497352B2 (en) * 2008-08-13 2013-07-30 Wntresearch Ab Use of Wnt5-α peptide derivates for the treatment of melanoma and gastric cancer
WO2013006129A1 (en) 2011-07-01 2013-01-10 Wntresearch Ab Treatment of prostate cancer and a method for determining the prognosis for prostate cancer patients
EP3193941B1 (de) 2014-08-06 2024-05-22 Ascendis Pharma A/S Prodrugs mit einem aminoalkylglycin-linker

Also Published As

Publication number Publication date
EP0252810B1 (de) 1991-04-17
EP0252810A2 (de) 1988-01-13
IL83092A0 (en) 1987-12-31
NO872832D0 (no) 1987-07-07
FI85583B (fi) 1992-01-31
IL83092A (en) 1991-11-21
JPS6323856A (ja) 1988-02-01
FR2601363A1 (fr) 1988-01-15
PT85280B (pt) 1990-03-30
FI873009A0 (fi) 1987-07-07
DK349287D0 (da) 1987-07-07
ATE62669T1 (de) 1991-05-15
NO872832L (no) 1988-01-11
NO164593C (no) 1990-10-24
CA1277330C (en) 1990-12-04
NZ220987A (en) 1989-12-21
KR880001587A (ko) 1988-04-25
HUT44482A (en) 1988-03-28
AU595340B2 (en) 1990-03-29
HU196169B (en) 1988-10-28
DE3769384D1 (de) 1991-05-23
EP0252810A3 (en) 1988-09-07
DK349287A (da) 1988-01-09
AU7529487A (en) 1988-01-14
FR2601363B1 (fr) 1988-10-21
US4840967A (en) 1989-06-20
FI873009A (fi) 1988-01-09
GR3002081T3 (en) 1992-12-30
FI85583C (fi) 1992-05-11
NO164593B (no) 1990-07-16
PT85280A (fr) 1987-08-01
CS357891A3 (en) 1992-12-16

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