FI873009A - Foerfarande foer framstaellning av (2-dimetylaminoetyl)-/2-/(2-tiometylfenyl)-(fenylmetyl)/amino-2-oxoetyl /karbamater eller -karbamider. - Google Patents

Foerfarande foer framstaellning av (2-dimetylaminoetyl)-/2-/(2-tiometylfenyl)-(fenylmetyl)/amino-2-oxoetyl /karbamater eller -karbamider. Download PDF

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Publication number
FI873009A
FI873009A FI873009A FI873009A FI873009A FI 873009 A FI873009 A FI 873009A FI 873009 A FI873009 A FI 873009A FI 873009 A FI873009 A FI 873009A FI 873009 A FI873009 A FI 873009A
Authority
FI
Finland
Prior art keywords
group
halogen atoms
carbamider
carbamater
thiomethylphenyl
Prior art date
Application number
FI873009A
Other languages
English (en)
Other versions
FI85583C (fi
FI873009A0 (fi
FI85583B (fi
Inventor
Nigel Beeley
Gerard Cremer
Original Assignee
Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo filed Critical Synthelabo
Publication of FI873009A0 publication Critical patent/FI873009A0/fi
Publication of FI873009A publication Critical patent/FI873009A/fi
Application granted granted Critical
Publication of FI85583B publication Critical patent/FI85583B/fi
Publication of FI85583C publication Critical patent/FI85583C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/39Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
    • C07C323/40Y being a hydrogen or a carbon atom
    • C07C323/41Y being a hydrogen or an acyclic carbon atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/12Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/14Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
    • C07C319/20Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides by reactions not involving the formation of sulfide groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicinal Preparation (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
FI873009A 1986-07-08 1987-07-07 Foerfarande foer framstaellning av terapeutiskt anvaendbara (2-dimetylaminoetyl)/2-/(2-metyltiofenyl)-(fenylmetyl)/amino-2-oxoetyl/ karbamater eller -karbamider. FI85583C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8609887 1986-07-08
FR8609887A FR2601363B1 (fr) 1986-07-08 1986-07-08 (dimethylamino)-2 ethyl) ((((methylthio)-2 phenyl) (phenylmethyl)amino)-2 oxo-2 ethyl) carbamates ou urees, leur preparation et leur application en therapeutique.

Publications (4)

Publication Number Publication Date
FI873009A0 FI873009A0 (fi) 1987-07-07
FI873009A true FI873009A (fi) 1988-01-09
FI85583B FI85583B (fi) 1992-01-31
FI85583C FI85583C (fi) 1992-05-11

Family

ID=9337176

Family Applications (1)

Application Number Title Priority Date Filing Date
FI873009A FI85583C (fi) 1986-07-08 1987-07-07 Foerfarande foer framstaellning av terapeutiskt anvaendbara (2-dimetylaminoetyl)/2-/(2-metyltiofenyl)-(fenylmetyl)/amino-2-oxoetyl/ karbamater eller -karbamider.

Country Status (19)

Country Link
US (1) US4840967A (fi)
EP (1) EP0252810B1 (fi)
JP (1) JPS6323856A (fi)
KR (1) KR880001587A (fi)
AT (1) ATE62669T1 (fi)
AU (1) AU595340B2 (fi)
CA (1) CA1277330C (fi)
CS (1) CS357891A3 (fi)
DE (1) DE3769384D1 (fi)
DK (1) DK349287A (fi)
FI (1) FI85583C (fi)
FR (1) FR2601363B1 (fi)
GR (1) GR3002081T3 (fi)
HU (1) HU196169B (fi)
IL (1) IL83092A (fi)
NO (1) NO164593C (fi)
NZ (1) NZ220987A (fi)
PT (1) PT85280B (fi)
ZA (1) ZA874945B (fi)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2641279B1 (fr) * 1989-01-03 1991-02-22 Synthelabo Derives de n-(amino-2 ethyl) n-(((methylthio-2 phenyl) (phenylmethyl)amino)-2 oxo ethyl)amides et carbamates, leur preparation et leur application en therapeutique
JPH02290464A (ja) * 1989-04-28 1990-11-30 Takagi Ind Co Ltd 瞬間湯沸器
EP0903341A1 (en) * 1997-07-22 1999-03-24 Akzo Nobel N.V. "Novel ortho-mercaptoaniline compounds"
CA2284864A1 (en) 1998-01-21 1999-07-29 Zymogenetics, Inc. Dialkyl ureas as calcitonin mimetics
KR20040074102A (ko) * 2001-12-27 2004-08-21 다이쇼 세이야꾸 가부시끼가이샤 카르복실산 유도체
FR2885129B1 (fr) * 2005-04-29 2007-06-15 Proskelia Sas Nouveaux derives de l'ureee substituee parun thiazole ou benzothiazole, leur procede de preparation, leur application a titre de medicaments, les compositions pharmaceutiques les renfermant et utilisation.
EP2091917A1 (en) * 2006-12-11 2009-08-26 Wyeth a Corporation of the State of Delaware Ion channel modulators
CN102105162B (zh) * 2008-08-13 2014-05-07 温特研究公司 Wnt5-α肽衍生物用于治疗黑色素瘤和胃癌的用途
WO2013006129A1 (en) 2011-07-01 2013-01-10 Wntresearch Ab Treatment of prostate cancer and a method for determining the prognosis for prostate cancer patients
US11633487B2 (en) 2014-08-06 2023-04-25 Ascendis Pharma A/S Prodrugs comprising an aminoalkyl glycine linker

Also Published As

Publication number Publication date
ATE62669T1 (de) 1991-05-15
FI85583C (fi) 1992-05-11
DK349287D0 (da) 1987-07-07
NO164593C (no) 1990-10-24
ZA874945B (en) 1988-02-24
EP0252810A2 (fr) 1988-01-13
NZ220987A (en) 1989-12-21
JPS6323856A (ja) 1988-02-01
NO872832D0 (no) 1987-07-07
NO164593B (no) 1990-07-16
KR880001587A (ko) 1988-04-25
DE3769384D1 (de) 1991-05-23
EP0252810A3 (en) 1988-09-07
FI873009A0 (fi) 1987-07-07
EP0252810B1 (fr) 1991-04-17
IL83092A (en) 1991-11-21
FI85583B (fi) 1992-01-31
AU7529487A (en) 1988-01-14
DK349287A (da) 1988-01-09
PT85280B (pt) 1990-03-30
HUT44482A (en) 1988-03-28
AU595340B2 (en) 1990-03-29
PT85280A (fr) 1987-08-01
FR2601363B1 (fr) 1988-10-21
HU196169B (en) 1988-10-28
IL83092A0 (en) 1987-12-31
GR3002081T3 (en) 1992-12-30
US4840967A (en) 1989-06-20
FR2601363A1 (fr) 1988-01-15
CS357891A3 (en) 1992-12-16
NO872832L (no) 1988-01-11
CA1277330C (en) 1990-12-04

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Owner name: SYNTHELABO