DE3769384D1 - N-2(dimethylamino)ethyl n.(2((2(methylthio)phenyl)(phenylmethyl))amino-2-oxo)ethyl) carbamidsaeureester und harnstoffe-herstellungsverfahren und therapeutisches mittel. - Google Patents

N-2(dimethylamino)ethyl n.(2((2(methylthio)phenyl)(phenylmethyl))amino-2-oxo)ethyl) carbamidsaeureester und harnstoffe-herstellungsverfahren und therapeutisches mittel.

Info

Publication number
DE3769384D1
DE3769384D1 DE8787401523T DE3769384T DE3769384D1 DE 3769384 D1 DE3769384 D1 DE 3769384D1 DE 8787401523 T DE8787401523 T DE 8787401523T DE 3769384 T DE3769384 T DE 3769384T DE 3769384 D1 DE3769384 D1 DE 3769384D1
Authority
DE
Germany
Prior art keywords
group
ethyl
methylthio
phenyl
carbamid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8787401523T
Other languages
English (en)
Inventor
Nigel Beeley
Gerard Cremer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo SA filed Critical Synthelabo SA
Application granted granted Critical
Publication of DE3769384D1 publication Critical patent/DE3769384D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/39—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
    • C07C323/40—Y being a hydrogen or a carbon atom
    • C07C323/41—Y being a hydrogen or an acyclic carbon atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/14—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
    • C07C319/20—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides by reactions not involving the formation of sulfide groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Steroid Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Medicinal Preparation (AREA)
DE8787401523T 1986-07-08 1987-07-01 N-2(dimethylamino)ethyl n.(2((2(methylthio)phenyl)(phenylmethyl))amino-2-oxo)ethyl) carbamidsaeureester und harnstoffe-herstellungsverfahren und therapeutisches mittel. Expired - Fee Related DE3769384D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8609887A FR2601363B1 (fr) 1986-07-08 1986-07-08 (dimethylamino)-2 ethyl) ((((methylthio)-2 phenyl) (phenylmethyl)amino)-2 oxo-2 ethyl) carbamates ou urees, leur preparation et leur application en therapeutique.

Publications (1)

Publication Number Publication Date
DE3769384D1 true DE3769384D1 (de) 1991-05-23

Family

ID=9337176

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8787401523T Expired - Fee Related DE3769384D1 (de) 1986-07-08 1987-07-01 N-2(dimethylamino)ethyl n.(2((2(methylthio)phenyl)(phenylmethyl))amino-2-oxo)ethyl) carbamidsaeureester und harnstoffe-herstellungsverfahren und therapeutisches mittel.

Country Status (19)

Country Link
US (1) US4840967A (de)
EP (1) EP0252810B1 (de)
JP (1) JPS6323856A (de)
KR (1) KR880001587A (de)
AT (1) ATE62669T1 (de)
AU (1) AU595340B2 (de)
CA (1) CA1277330C (de)
CS (1) CS357891A3 (de)
DE (1) DE3769384D1 (de)
DK (1) DK349287A (de)
FI (1) FI85583C (de)
FR (1) FR2601363B1 (de)
GR (1) GR3002081T3 (de)
HU (1) HU196169B (de)
IL (1) IL83092A (de)
NO (1) NO164593C (de)
NZ (1) NZ220987A (de)
PT (1) PT85280B (de)
ZA (1) ZA874945B (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2641279B1 (fr) * 1989-01-03 1991-02-22 Synthelabo Derives de n-(amino-2 ethyl) n-(((methylthio-2 phenyl) (phenylmethyl)amino)-2 oxo ethyl)amides et carbamates, leur preparation et leur application en therapeutique
JPH02290464A (ja) * 1989-04-28 1990-11-30 Takagi Ind Co Ltd 瞬間湯沸器
EP0903341A1 (de) * 1997-07-22 1999-03-24 Akzo Nobel N.V. Ortho-Mercaptoanilinverbindungen
CA2284864A1 (en) 1998-01-21 1999-07-29 Zymogenetics, Inc. Dialkyl ureas as calcitonin mimetics
JPWO2003055847A1 (ja) * 2001-12-27 2005-05-12 大正製薬株式会社 カルボン酸誘導体
FR2885129B1 (fr) * 2005-04-29 2007-06-15 Proskelia Sas Nouveaux derives de l'ureee substituee parun thiazole ou benzothiazole, leur procede de preparation, leur application a titre de medicaments, les compositions pharmaceutiques les renfermant et utilisation.
JP2010512417A (ja) * 2006-12-11 2010-04-22 ワイス エルエルシー イオンチャネルモジュレータ−
RU2517190C2 (ru) * 2008-08-13 2014-05-27 Внтрисерч Аб Применение производных пептида wnt5-a для лечения меланомы и рака желудка
EP2726880B1 (de) 2011-07-01 2019-04-17 Wntresearch AB Behandlung von prostatakrebs und verfahren zur bestimmung der prognose von prostatakrebspatienten
CA2955569C (en) * 2014-08-06 2023-02-14 Ascendis Pharma A/S Prodrugs comprising an aminoalkyl glycine linker

Also Published As

Publication number Publication date
GR3002081T3 (en) 1992-12-30
EP0252810A2 (de) 1988-01-13
NO164593B (no) 1990-07-16
DK349287D0 (da) 1987-07-07
CS357891A3 (en) 1992-12-16
FI85583B (fi) 1992-01-31
NO872832D0 (no) 1987-07-07
PT85280A (fr) 1987-08-01
NO872832L (no) 1988-01-11
ATE62669T1 (de) 1991-05-15
PT85280B (pt) 1990-03-30
DK349287A (da) 1988-01-09
US4840967A (en) 1989-06-20
FR2601363A1 (fr) 1988-01-15
IL83092A (en) 1991-11-21
HUT44482A (en) 1988-03-28
KR880001587A (ko) 1988-04-25
EP0252810B1 (de) 1991-04-17
EP0252810A3 (en) 1988-09-07
JPS6323856A (ja) 1988-02-01
IL83092A0 (en) 1987-12-31
NZ220987A (en) 1989-12-21
HU196169B (en) 1988-10-28
FR2601363B1 (fr) 1988-10-21
AU7529487A (en) 1988-01-14
AU595340B2 (en) 1990-03-29
FI85583C (fi) 1992-05-11
ZA874945B (en) 1988-02-24
FI873009A (fi) 1988-01-09
CA1277330C (en) 1990-12-04
NO164593C (no) 1990-10-24
FI873009A0 (fi) 1987-07-07

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee