MX9504349A - Derivados de aroilpiperidina. - Google Patents

Derivados de aroilpiperidina.

Info

Publication number
MX9504349A
MX9504349A MX9504349A MX9504349A MX9504349A MX 9504349 A MX9504349 A MX 9504349A MX 9504349 A MX9504349 A MX 9504349A MX 9504349 A MX9504349 A MX 9504349A MX 9504349 A MX9504349 A MX 9504349A
Authority
MX
Mexico
Prior art keywords
aroylpiperidine
derivatives
trifluoromethyl
pipindependently
naphtoylamino
Prior art date
Application number
MX9504349A
Other languages
English (en)
Inventor
Silvio Ofner
Siem Jacob Veenstra
Walter Schilling
Original Assignee
Novartis Ag Tambien Denominada
Y O Novartis Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag Tambien Denominada, Y O Novartis Inc filed Critical Novartis Ag Tambien Denominada
Publication of MX9504349A publication Critical patent/MX9504349A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Immunology (AREA)
  • Hospice & Palliative Care (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)

Abstract

La invencion se refiere a novedosas N-(3,5-bis-trifluorometil-benzoil)-2-bencil-4-(aza naftoilamino)-piperidinas de la formula I, en donde X e Y son cl anillo A está insustituido o mono- o polisustituido por sustituyentes seleccionados a partir del grupo que consiste en alquilo inferior, alcoxi inferior, halogeno, nitro, y trifluorometilo; y a las sales de los mismos, al uso de los mismos, a procesos para la preparacion de los mismos, y a composiciones farmacéuticas que comprenden un compuesto de acuerdo con la invencion o una sal farmacéuticamente aceptable de las mismas.
MX9504349A 1994-10-14 1995-10-13 Derivados de aroilpiperidina. MX9504349A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH309194 1994-10-14

Publications (1)

Publication Number Publication Date
MX9504349A true MX9504349A (es) 1997-03-29

Family

ID=4248427

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9504349A MX9504349A (es) 1994-10-14 1995-10-13 Derivados de aroilpiperidina.

Country Status (23)

Country Link
US (1) US5965562A (es)
EP (1) EP0707006B1 (es)
JP (1) JP3022951B2 (es)
KR (1) KR100413985B1 (es)
CN (1) CN1066445C (es)
AT (1) ATE178602T1 (es)
AU (1) AU705851B2 (es)
CA (1) CA2160444C (es)
DE (1) DE59505575D1 (es)
DK (1) DK0707006T3 (es)
ES (1) ES2132580T3 (es)
FI (1) FI114795B (es)
GR (1) GR3030515T3 (es)
HU (1) HUT74103A (es)
IL (1) IL115572A (es)
MX (1) MX9504349A (es)
MY (1) MY114679A (es)
NO (1) NO308034B1 (es)
NZ (1) NZ280212A (es)
RU (1) RU2158731C2 (es)
SA (1) SA96160637B1 (es)
TW (1) TW397825B (es)
ZA (1) ZA958647B (es)

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AU2898297A (en) * 1996-05-24 1998-01-05 Novartis Ag Use of substance p antagonists for treating social phobia
AR018376A1 (es) * 1998-05-26 2001-11-14 Novartis Ag Composiciones farmaceuticas que se pueden dispersar de una manera espontanea y el uso de las mismas para la manufactura de un medicamento
BR9913201A (pt) * 1998-08-25 2001-05-08 Novartis Ag Uso de antagonista da substância p para o tratamento da sìndrome da fadiga crÈnica e/ou fibromialgia e uso de antagonistas do recptor de nk-1 para tratamento da sìndrome da fadiga crÈnica
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GB0220953D0 (en) * 2002-09-10 2002-10-23 Novartis Ag Organic compounds
GB2394417A (en) * 2002-10-24 2004-04-28 Novartis Ag Solid dispersion comprising a piperidine substance P antagonist and a carrier
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AR071997A1 (es) 2008-06-04 2010-07-28 Bristol Myers Squibb Co Forma cristalina de 6-((4s)-2-metil-4-(2-naftil)-1,2,3,4-tetrahidroisoquinolin-7-il)piridazin-3-amina
US9156812B2 (en) 2008-06-04 2015-10-13 Bristol-Myers Squibb Company Crystalline form of 6-[(4S)-2-methyl-4-(2-naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine
WO2010114780A1 (en) 2009-04-01 2010-10-07 Merck Sharp & Dohme Corp. Inhibitors of akt activity
JP2012526823A (ja) 2009-05-12 2012-11-01 アルバニー モレキュラー リサーチ， インコーポレイテッド アリール、ヘテロアリール、および複素環置換テトラヒドロイソキノリンならびにそれらの使用
PE20120373A1 (es) 2009-05-12 2012-05-17 Albany Molecular Res Inc 7-([1,2,4]triazolo[1,5-a]piridin-6-il)-4-(3,4-diclorofenil)-1,2,3,4-tetrahidroisoquinolina
US8815894B2 (en) 2009-05-12 2014-08-26 Bristol-Myers Squibb Company Crystalline forms of (S)-7-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydroisoquinoline and use thereof
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Also Published As

Publication number Publication date
US5965562A (en) 1999-10-12
KR100413985B1 (ko) 2004-03-26
HUT74103A (en) 1996-11-28
JPH08176145A (ja) 1996-07-09
CN1066445C (zh) 2001-05-30
JP3022951B2 (ja) 2000-03-21
GR3030515T3 (en) 1999-10-29
NO954067D0 (no) 1995-10-13
NO308034B1 (no) 2000-07-10
FI114795B (fi) 2004-12-31
ATE178602T1 (de) 1999-04-15
DE59505575D1 (de) 1999-05-12
TW397825B (en) 2000-07-11
FI954829L (fi) 1996-04-15
CN1133839A (zh) 1996-10-23
AU3317495A (en) 1996-04-26
KR960014121A (ko) 1996-05-22
CA2160444C (en) 2006-11-28
RU2158731C2 (ru) 2000-11-10
CA2160444A1 (en) 1996-04-15
EP0707006A1 (de) 1996-04-17
IL115572A0 (en) 1996-01-19
MY114679A (en) 2002-12-31
AU705851B2 (en) 1999-06-03
HU9502973D0 (en) 1995-12-28
DK0707006T3 (da) 1999-10-18
NO954067L (no) 1996-04-15
NZ280212A (en) 2001-10-26
IL115572A (en) 2001-05-20
ZA958647B (en) 1996-04-15
FI954829A0 (fi) 1995-10-11
ES2132580T3 (es) 1999-08-16
EP0707006B1 (de) 1999-04-07
SA96160637B1 (ar) 2005-06-14

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