ZA864715B - 2-oxy-4h-3,1-benzoxazin-4-one derivatives and related compounds - Google Patents

2-oxy-4h-3,1-benzoxazin-4-one derivatives and related compounds

Info

Publication number
ZA864715B
ZA864715B ZA864715A ZA864715A ZA864715B ZA 864715 B ZA864715 B ZA 864715B ZA 864715 A ZA864715 A ZA 864715A ZA 864715 A ZA864715 A ZA 864715A ZA 864715 B ZA864715 B ZA 864715B
Authority
ZA
South Africa
Prior art keywords
benzoxazin
oxy
derivatives
related compounds
compounds
Prior art date
Application number
ZA864715A
Other languages
English (en)
Inventor
Alexander Krantz
Robin W Spencer
Tim Tam
Teng J Liak
Original Assignee
Syntex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex Inc filed Critical Syntex Inc
Publication of ZA864715B publication Critical patent/ZA864715B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
    • C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
    • C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D265/24—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in positions 2 and 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
    • C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
    • C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D265/24—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in positions 2 and 4
    • C07D265/26—Two oxygen atoms, e.g. isatoic anhydride
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
    • C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
    • C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D265/18—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6527—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07F9/6533—Six-membered rings
    • C07F9/65335—Six-membered rings condensed with carbocyclic rings or carbocyclic ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
ZA864715A 1985-06-25 1986-06-24 2-oxy-4h-3,1-benzoxazin-4-one derivatives and related compounds ZA864715B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/748,631 US4665070A (en) 1985-06-25 1985-06-25 2-oxy-4H-3,1-benzoxazin-4-ones and pharmaceutical use

Publications (1)

Publication Number Publication Date
ZA864715B true ZA864715B (en) 1988-02-24

Family

ID=25010264

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA864715A ZA864715B (en) 1985-06-25 1986-06-24 2-oxy-4h-3,1-benzoxazin-4-one derivatives and related compounds

Country Status (13)

Country Link
US (1) US4665070A (xx)
EP (1) EP0206323A1 (xx)
JP (1) JPS6230770A (xx)
KR (1) KR900004319B1 (xx)
AU (2) AU599320B2 (xx)
CA (1) CA1270487A (xx)
DK (1) DK297486A (xx)
ES (4) ES8802223A1 (xx)
FI (1) FI862691A (xx)
HU (1) HU196772B (xx)
IL (1) IL79222A0 (xx)
NO (1) NO163486C (xx)
ZA (1) ZA864715B (xx)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4745116A (en) * 1985-06-25 1988-05-17 Syntex (U.S.A.) Inc. 2-oxy-4H-3,1-benzoxazin-4-ones and related compounds and pharmaceutical use
CA1309556C (en) * 1987-06-09 1992-10-27 Masayuki Kokubo 4h-3,1-benzoxazin-4-one compounds and pharmaceutical composition thereoffor the inhibition of serine proteases
WO1991015487A1 (fr) * 1990-03-30 1991-10-17 Japan Tobacco Inc. Nouveau derive de 4-1-benzoxazine-4h-3,1
US5985872A (en) * 1995-05-24 1999-11-16 G.D. Searle & Co. 2-amino-benzoxazinones for the treatment of viral infections
FR2763944B1 (fr) * 1997-06-03 2000-12-15 Centre Nat Rech Scient Nouveaux derives de coumarines, leurs procedes de preparation et leur application comme medicaments en tant qu'inhibiteurs de proteases
WO1999048878A1 (en) * 1998-03-24 1999-09-30 Novo Nordisk A/S Heterocyclic compounds regulating clotting
US6180625B1 (en) 1998-03-24 2001-01-30 Novo Nordisk A/S Heterocyclic compounds regulating clotting
WO2000030646A1 (en) * 1998-11-26 2000-06-02 Novo Nordisk A/S Heterocyclic compounds regulating clotting
AR022204A1 (es) * 1999-01-08 2002-09-04 Norgine Bv Compuesto, proceso para su preparacion, composicion farmaceutica y producto comestible que lo comprende.
GB9900416D0 (en) * 1999-01-08 1999-02-24 Alizyme Therapeutics Ltd Inhibitors
WO2001018181A2 (en) * 1999-09-10 2001-03-15 The Procter & Gamble Company Enzyme inhibitors
EP1628674A2 (en) * 2003-05-06 2006-03-01 Cytovia, Inc. Protease inhibitors for coronaviruses and sars-cov and the use thereof
ES2380135T3 (es) 2006-11-22 2012-05-08 Ajinomoto Co., Inc. Método de preparación de derivados de fenilalanina que tienen esqueleto de quinazolinadiona e intermedios para su preparación
JP2010254623A (ja) * 2009-04-24 2010-11-11 Takeda Chem Ind Ltd ベンゾオキサジノン化合物の結晶

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU173974B (hu) * 1971-08-30 1979-10-28 Chinoin Gyogyszer Es Vegyeszet Sposob poluchenija proizvodnykh 3,1-benzoksazin-4-ona

Also Published As

Publication number Publication date
ES8801807A1 (es) 1988-03-01
NO163486B (no) 1990-02-26
ES557730A0 (es) 1988-03-01
IL79222A0 (en) 1986-09-30
NO163486C (no) 1990-06-13
AU599320B2 (en) 1990-07-19
CA1270487A (en) 1990-06-19
DK297486D0 (da) 1986-06-24
EP0206323A1 (en) 1986-12-30
DK297486A (da) 1986-12-26
NO862534D0 (no) 1986-06-24
HUT41750A (en) 1987-05-28
ES556514A0 (es) 1988-05-01
AU5915086A (en) 1987-01-08
AU4912090A (en) 1990-05-31
FI862691A0 (fi) 1986-06-24
ES8801806A1 (es) 1988-03-01
ES8801808A1 (es) 1988-03-01
NO862534L (no) 1986-12-29
HU196772B (en) 1989-01-30
KR870000310A (ko) 1987-02-17
US4665070A (en) 1987-05-12
JPS6230770A (ja) 1987-02-09
ES8802223A1 (es) 1988-05-01
KR900004319B1 (ko) 1990-06-22
ES557732A0 (es) 1988-03-01
ES557731A0 (es) 1988-03-01
FI862691A (fi) 1986-12-26

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