NO163486C - Analogifremgangsmaate for fremstilling av terapeutisk virksomme 2-oxy-4h-3,1-benzoxazin-4-on-derivater. - Google Patents

Analogifremgangsmaate for fremstilling av terapeutisk virksomme 2-oxy-4h-3,1-benzoxazin-4-on-derivater.

Info

Publication number
NO163486C
NO163486C NO862534A NO862534A NO163486C NO 163486 C NO163486 C NO 163486C NO 862534 A NO862534 A NO 862534A NO 862534 A NO862534 A NO 862534A NO 163486 C NO163486 C NO 163486C
Authority
NO
Norway
Prior art keywords
benzoxazin
oxy
derivatives
preparation
therapeutic activity
Prior art date
Application number
NO862534A
Other languages
English (en)
Other versions
NO862534L (no
NO163486B (no
NO862534D0 (no
Inventor
Alexander Krantz
Robin W Spencer
Tim Tam
Teng J Liak
Original Assignee
Syntex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex Inc filed Critical Syntex Inc
Publication of NO862534D0 publication Critical patent/NO862534D0/no
Publication of NO862534L publication Critical patent/NO862534L/no
Priority to NO871576A priority Critical patent/NO166176C/no
Publication of NO163486B publication Critical patent/NO163486B/no
Publication of NO163486C publication Critical patent/NO163486C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
    • C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
    • C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D265/24—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in positions 2 and 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
    • C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
    • C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D265/24—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in positions 2 and 4
    • C07D265/26—Two oxygen atoms, e.g. isatoic anhydride
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
    • C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
    • C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D265/18—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6527—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07F9/6533—Six-membered rings
    • C07F9/65335—Six-membered rings condensed with carbocyclic rings or carbocyclic ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
NO862534A 1985-06-25 1986-06-24 Analogifremgangsmaate for fremstilling av terapeutisk virksomme 2-oxy-4h-3,1-benzoxazin-4-on-derivater. NO163486C (no)

Priority Applications (1)

Application Number Priority Date Filing Date Title
NO871576A NO166176C (no) 1985-06-25 1987-04-14 Anthranilsyrederivater.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/748,631 US4665070A (en) 1985-06-25 1985-06-25 2-oxy-4H-3,1-benzoxazin-4-ones and pharmaceutical use

Publications (4)

Publication Number Publication Date
NO862534D0 NO862534D0 (no) 1986-06-24
NO862534L NO862534L (no) 1986-12-29
NO163486B NO163486B (no) 1990-02-26
NO163486C true NO163486C (no) 1990-06-13

Family

ID=25010264

Family Applications (1)

Application Number Title Priority Date Filing Date
NO862534A NO163486C (no) 1985-06-25 1986-06-24 Analogifremgangsmaate for fremstilling av terapeutisk virksomme 2-oxy-4h-3,1-benzoxazin-4-on-derivater.

Country Status (13)

Country Link
US (1) US4665070A (no)
EP (1) EP0206323A1 (no)
JP (1) JPS6230770A (no)
KR (1) KR900004319B1 (no)
AU (2) AU599320B2 (no)
CA (1) CA1270487A (no)
DK (1) DK297486A (no)
ES (4) ES8802223A1 (no)
FI (1) FI862691A (no)
HU (1) HU196772B (no)
IL (1) IL79222A0 (no)
NO (1) NO163486C (no)
ZA (1) ZA864715B (no)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4745116A (en) * 1985-06-25 1988-05-17 Syntex (U.S.A.) Inc. 2-oxy-4H-3,1-benzoxazin-4-ones and related compounds and pharmaceutical use
CA1309556C (en) * 1987-06-09 1992-10-27 Masayuki Kokubo 4h-3,1-benzoxazin-4-one compounds and pharmaceutical composition thereoffor the inhibition of serine proteases
WO1991015487A1 (fr) * 1990-03-30 1991-10-17 Japan Tobacco Inc. Nouveau derive de 4-1-benzoxazine-4h-3,1
US5985872A (en) * 1995-05-24 1999-11-16 G.D. Searle & Co. 2-amino-benzoxazinones for the treatment of viral infections
FR2763944B1 (fr) * 1997-06-03 2000-12-15 Centre Nat Rech Scient Nouveaux derives de coumarines, leurs procedes de preparation et leur application comme medicaments en tant qu'inhibiteurs de proteases
US6180625B1 (en) 1998-03-24 2001-01-30 Novo Nordisk A/S Heterocyclic compounds regulating clotting
WO1999048878A1 (en) * 1998-03-24 1999-09-30 Novo Nordisk A/S Heterocyclic compounds regulating clotting
WO2000030646A1 (en) * 1998-11-26 2000-06-02 Novo Nordisk A/S Heterocyclic compounds regulating clotting
AR022204A1 (es) * 1999-01-08 2002-09-04 Norgine Bv Compuesto, proceso para su preparacion, composicion farmaceutica y producto comestible que lo comprende.
GB9900416D0 (en) * 1999-01-08 1999-02-24 Alizyme Therapeutics Ltd Inhibitors
EP1212098A2 (en) * 1999-09-10 2002-06-12 The Procter & Gamble Company Enzyme inhibitors
US7504382B2 (en) * 2003-05-06 2009-03-17 Cytovia, Inc. Protease inhibitors for coronaviruses and SARS-CoV and the use thereof
EP2103601B1 (en) * 2006-11-22 2012-03-14 Ajinomoto Co., Inc. Process for production of phenylalanine derivatives having quinazolinedione skeletons and intermediates for the production
JP2010254623A (ja) * 2009-04-24 2010-11-11 Takeda Chem Ind Ltd ベンゾオキサジノン化合物の結晶

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU173974B (hu) * 1971-08-30 1979-10-28 Chinoin Gyogyszer Es Vegyeszet Sposob poluchenija proizvodnykh 3,1-benzoksazin-4-ona

Also Published As

Publication number Publication date
AU4912090A (en) 1990-05-31
ES557731A0 (es) 1988-03-01
IL79222A0 (en) 1986-09-30
AU5915086A (en) 1987-01-08
ES8802223A1 (es) 1988-05-01
US4665070A (en) 1987-05-12
ES556514A0 (es) 1988-05-01
KR900004319B1 (ko) 1990-06-22
FI862691A (fi) 1986-12-26
HU196772B (en) 1989-01-30
JPS6230770A (ja) 1987-02-09
NO862534L (no) 1986-12-29
AU599320B2 (en) 1990-07-19
ES8801807A1 (es) 1988-03-01
ES557732A0 (es) 1988-03-01
ES557730A0 (es) 1988-03-01
FI862691A0 (fi) 1986-06-24
ZA864715B (en) 1988-02-24
DK297486A (da) 1986-12-26
CA1270487A (en) 1990-06-19
ES8801806A1 (es) 1988-03-01
NO163486B (no) 1990-02-26
NO862534D0 (no) 1986-06-24
EP0206323A1 (en) 1986-12-30
ES8801808A1 (es) 1988-03-01
HUT41750A (en) 1987-05-28
KR870000310A (ko) 1987-02-17
DK297486D0 (da) 1986-06-24

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