ZA859462B - New pteridines,processes for preparing them and their use as intermediate products or as pharmaceutical compositions - Google Patents

New pteridines,processes for preparing them and their use as intermediate products or as pharmaceutical compositions

Info

Publication number
ZA859462B
ZA859462B ZA859462A ZA859462A ZA859462B ZA 859462 B ZA859462 B ZA 859462B ZA 859462 A ZA859462 A ZA 859462A ZA 859462 A ZA859462 A ZA 859462A ZA 859462 B ZA859462 B ZA 859462B
Authority
ZA
South Africa
Prior art keywords
preparing
processes
pharmaceutical compositions
intermediate products
pteridines
Prior art date
Application number
ZA859462A
Other languages
English (en)
Inventor
Josef Roch
Armin Heckel
Josef Nickl
Erich Mueller
Berthold Narr
Rainer Zimmermann
Hans Weisenberger
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of ZA859462B publication Critical patent/ZA859462B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D475/00—Heterocyclic compounds containing pteridine ring systems
    • C07D475/06—Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4
    • C07D475/08—Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4 with a nitrogen atom directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
ZA859462A 1984-12-12 1985-12-11 New pteridines,processes for preparing them and their use as intermediate products or as pharmaceutical compositions ZA859462B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19843445298 DE3445298A1 (de) 1984-12-12 1984-12-12 Neue pteridine, verfahren zu ihrer herstellung und deren verwendung als zwischenprodukte oder als arzneimittel

Publications (1)

Publication Number Publication Date
ZA859462B true ZA859462B (en) 1987-07-29

Family

ID=6252576

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA859462A ZA859462B (en) 1984-12-12 1985-12-11 New pteridines,processes for preparing them and their use as intermediate products or as pharmaceutical compositions

Country Status (15)

Country Link
EP (1) EP0185259A3 (forum.php)
JP (1) JPS61140585A (forum.php)
AU (1) AU576924B2 (forum.php)
CA (1) CA1252783A (forum.php)
DE (1) DE3445298A1 (forum.php)
DK (1) DK161327C (forum.php)
ES (1) ES8707238A1 (forum.php)
FI (1) FI82696C (forum.php)
GR (1) GR852996B (forum.php)
IL (1) IL77294A (forum.php)
NO (1) NO161373C (forum.php)
NZ (1) NZ214522A (forum.php)
PH (1) PH24451A (forum.php)
PT (1) PT81650B (forum.php)
ZA (1) ZA859462B (forum.php)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7276506B2 (en) 1998-12-28 2007-10-02 4 Aza Bioscience Nv Immunosuppressive effects of pteridine derivatives
BR0211310A (pt) * 2001-06-28 2006-10-31 Pliva D D compostos heterocìclicos e seus usos como inibidores de d-alanil, d-alanina ligase
DE10202468A1 (de) * 2002-01-23 2004-09-30 Faustus Forschungs Cie. Translational Cancer Research Gmbh Pteridinderivate, Verfahren zu deren Herstellung und ihre Verwendung
CA2534151A1 (en) * 2003-08-29 2005-03-10 4 Aza Bioscience Nv Immunosuppressive effects of pteridine derivatives
AU2004283479A1 (en) * 2003-10-17 2005-05-06 4 Aza Bioscience Nv Heterocycle-substituted pteridine derivatives and their use in therapy
GB2407089A (en) * 2003-10-17 2005-04-20 4 Aza Bioscience Nv Pteridine derivatives
CN1950081A (zh) * 2004-03-04 2007-04-18 神经能质公司 芳烷氨基取代的喹唑啉类似物
DE102004057645A1 (de) * 2004-11-29 2006-06-01 Boehringer Ingelheim Pharma Gmbh & Co. Kg Substituierte Pteridine zur Behandlung von entzündlichen Erkrankungen
DE102004057618A1 (de) 2004-11-29 2006-06-01 Boehringer Ingelheim Pharma Gmbh & Co. Kg Substituierte Pteridine zur Behandlung von entzündlichen Erkrankungen
DE102004057595A1 (de) 2004-11-29 2006-06-08 Boehringer Ingelheim Pharma Gmbh & Co. Kg Substituierte Pteridine zur Behandlung von entzündlichen Erkrankungen
DE102004057594A1 (de) 2004-11-29 2006-06-08 Boehringer Ingelheim Pharma Gmbh & Co. Kg Substitueirte Pteridine zur Behandlung von entzündlichen Erkrankungen
CA2628920C (en) * 2005-11-22 2015-12-29 Kudos Pharmaceuticals Limited Pyrido-,pyrazo- and pyrimido-pyrimidine derivatives as mtor inhibitors
RU2445315C2 (ru) * 2005-11-22 2012-03-20 Кудос Фармасьютиклз Лимитед ПРОИЗВОДНЫЕ ПИРИДО-, ПИРАЗО- И ПИРИМИДО-ПИРИМИДИНА И ИХ ПРИМЕНЕНИЕ В КАЧЕСТВЕ ИНГИБИТОРОВ mTOR
EP2032585B1 (de) 2006-05-24 2014-07-23 Boehringer Ingelheim International GmbH Substituierte pteridine als therapeutika
US10144736B2 (en) 2006-07-20 2018-12-04 Gilead Sciences, Inc. Substituted pteridines useful for the treatment and prevention of viral infections
US9259426B2 (en) 2006-07-20 2016-02-16 Gilead Sciences, Inc. 4,6-di- and 2,4,6-trisubstituted quinazoline derivatives useful for treating viral infections
EP2057156B1 (en) 2006-08-23 2017-02-01 KuDOS Pharmaceuticals Limited 2-methylmorpholine pyrido-,pyrazo- and pyrimido-pyrimidine derivatives as mtor inhibitors
US8198441B2 (en) 2008-06-20 2012-06-12 Astrazeneca Ab Process for the preparation of novel pyridopyrazines as mTOR kinase inhibitors
SI3097102T1 (en) 2015-03-04 2018-02-28 Gilead Sciences, Inc. Toll-like receptor modulating 4,6-diamino-pyrido(3,2-d)pyrimidine compounds
US10640499B2 (en) 2016-09-02 2020-05-05 Gilead Sciences, Inc. Toll like receptor modulator compounds
AU2017318601B2 (en) 2016-09-02 2020-09-03 Gilead Sciences, Inc. Toll like receptor modulator compounds
TWI751516B (zh) 2019-04-17 2022-01-01 美商基利科學股份有限公司 類鐸受體調節劑之固體形式
TWI751517B (zh) 2019-04-17 2022-01-01 美商基利科學股份有限公司 類鐸受體調節劑之固體形式
TWI879779B (zh) 2019-06-28 2025-04-11 美商基利科學股份有限公司 類鐸受體調節劑化合物的製備方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3159628A (en) * 1962-05-28 1964-12-01 Smith Kline French Lab Pteridine-5-oxide derivatives
DE3323932A1 (de) * 1983-07-02 1985-01-10 Dr. Karl Thomae Gmbh, 7950 Biberach Neue 2-piperazino-pteridine, verfahren zu ihrer herstellung und diese verbindung enthaltende arzneimittel

Also Published As

Publication number Publication date
DK161327C (da) 1991-12-09
DK161327B (da) 1991-06-24
DK572685A (da) 1986-06-13
PH24451A (en) 1990-06-25
FI82696B (fi) 1990-12-31
GR852996B (forum.php) 1986-04-16
PT81650A (de) 1986-01-01
NO161373C (no) 1989-08-09
NZ214522A (en) 1988-07-28
DE3445298A1 (de) 1986-06-12
FI854862A0 (fi) 1985-12-10
DK572685D0 (da) 1985-12-11
NO161373B (no) 1989-05-02
IL77294A (en) 1989-02-28
JPS61140585A (ja) 1986-06-27
PT81650B (pt) 1988-04-21
EP0185259A2 (de) 1986-06-25
FI82696C (fi) 1991-04-10
NO854965L (no) 1986-06-13
AU576924B2 (en) 1988-09-08
CA1252783A (en) 1989-04-18
EP0185259A3 (de) 1989-03-01
FI854862A7 (fi) 1986-06-13
AU5123285A (en) 1986-06-19
ES8707238A1 (es) 1987-07-16
ES549806A0 (es) 1987-07-16

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