ZA858733B - Alkyl-1-cyclopropyl,1,4-dihydro-4-oxo-3-quinolinecarboxylic acids,a process for their preparation and antibacterial agents containing these compounds - Google Patents

Alkyl-1-cyclopropyl,1,4-dihydro-4-oxo-3-quinolinecarboxylic acids,a process for their preparation and antibacterial agents containing these compounds

Info

Publication number
ZA858733B
ZA858733B ZA858733A ZA858733A ZA858733B ZA 858733 B ZA858733 B ZA 858733B ZA 858733 A ZA858733 A ZA 858733A ZA 858733 A ZA858733 A ZA 858733A ZA 858733 B ZA858733 B ZA 858733B
Authority
ZA
South Africa
Prior art keywords
cyclopropyl
dihydro
oxo
alkyl
compounds
Prior art date
Application number
ZA858733A
Other languages
English (en)
Inventor
Klaus Grohe
Michael Schriewer
Hans-Joachim Zeiler
Karl Georg Metzger
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of ZA858733B publication Critical patent/ZA858733B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/116—Heterocyclic compounds
    • A23K20/132—Heterocyclic compounds containing only one nitrogen as hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Health & Medical Sciences (AREA)
  • Food Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Animal Husbandry (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Fodder In General (AREA)
  • Quinoline Compounds (AREA)
ZA858733A 1984-11-15 1985-11-14 Alkyl-1-cyclopropyl,1,4-dihydro-4-oxo-3-quinolinecarboxylic acids,a process for their preparation and antibacterial agents containing these compounds ZA858733B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19843441788 DE3441788A1 (de) 1984-11-15 1984-11-15 Alkyl-1-cyclopropyl-1,4-dihydro-4-oxo-3-chinolincarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel

Publications (1)

Publication Number Publication Date
ZA858733B true ZA858733B (en) 1986-07-30

Family

ID=6250391

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA858733A ZA858733B (en) 1984-11-15 1985-11-14 Alkyl-1-cyclopropyl,1,4-dihydro-4-oxo-3-quinolinecarboxylic acids,a process for their preparation and antibacterial agents containing these compounds

Country Status (14)

Country Link
US (1) US4762844A (es)
EP (1) EP0181588A3 (es)
JP (1) JPS61122272A (es)
KR (1) KR870000784B1 (es)
AU (1) AU572702B2 (es)
BR (1) BR8505734A (es)
CA (1) CA1260478A (es)
CS (1) CS252835B2 (es)
DE (1) DE3441788A1 (es)
ES (1) ES8700851A1 (es)
FI (1) FI854466A (es)
HU (1) HU194178B (es)
PL (1) PL145639B1 (es)
ZA (1) ZA858733B (es)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3318145A1 (de) * 1983-05-18 1984-11-22 Bayer Ag, 5090 Leverkusen 7-amino-1-cyclopropyl-6,8-difluor-1,4-dihydro-4-oxo-3-chinolincarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
AU576272B2 (en) * 1984-11-13 1988-08-18 Kyorin Pharmaceutical Co. Ltd. Quinolone carboxylic acid derivates
JPS62215572A (ja) * 1986-03-17 1987-09-22 Kyorin Pharmaceut Co Ltd キノロンカルボン酸誘導体
DE3615767A1 (de) * 1986-05-10 1987-11-12 Bayer Ag Verfahren zur herstellung von 4-hydroxy-chinolin-3-carbonsaeuren
US5563138A (en) * 1987-04-16 1996-10-08 Otsuka Pharmaceutical Company, Limited Benzoheterocyclic compounds
US5290934A (en) * 1987-04-16 1994-03-01 Otsuka Pharmaceutical Company, Limited Benzoheterocyclic compounds
DE3724466A1 (de) * 1987-07-24 1989-02-02 Bayer Ag Verfahren zur herstellung von chinoloncarbonsaeuren
US4929613A (en) * 1987-08-26 1990-05-29 Warner-Lambert Company Antibacterial agents
DE3811341A1 (de) * 1987-10-09 1989-04-27 Bayer Ag In 7-stellung c-verknuepfte chinolon- und 1,8-naphthyridin-4-on-carbonsaeure und ein verfahren zu ihrer herstellung
EP0342849A3 (en) * 1988-05-19 1990-03-14 Pfizer Inc. Intermediates for preparing 1,4-dihydro-4-oxo-quinoline-3-carboxylic acid esters
US5103040A (en) * 1988-06-21 1992-04-07 Pfizer Inc. 6-fluoro-1,4-dihydroquinol-4-one-3-carboxylic acid derivatives and intermediates therefor
US5104868A (en) * 1988-06-21 1992-04-14 Pfizer Inc. Tricyclic derivatives of 7-substituted-6-fluoro-1,4-dihydroquinol-4-one-3-carboxylic acids and esters
US5039682A (en) * 1988-06-21 1991-08-13 Pfizer Inc. 6-fluoro-1,4-dihydroquinol-4-one-3-carboxylic acid derivatives and intermediates therefor
US5233091A (en) * 1988-06-21 1993-08-03 Pfizer Inc. 6-fluoro-1,4-dihydroquinol-4-one-3-carboxylic acid derivatives and intermediates therefor
JP2915068B2 (ja) * 1990-05-07 1999-07-05 岩城製薬株式会社 ジヒドロフラノン誘導体の製造方法
DE4301246A1 (de) * 1993-01-19 1994-07-21 Bayer Ag Chinolon- und Naphthyridoncarbonsäurederivate
JP3346766B2 (ja) * 1998-04-06 2002-11-18 富山化学工業株式会社 キノロンカルボン酸誘導体またはその塩
DE10108750A1 (de) * 2001-02-23 2002-09-05 Bayer Ag Verbessertes Verfahren zur Herstellung von Fluorchinoloncarbonsäuren
KR100519158B1 (ko) * 2002-12-21 2005-10-06 주식회사유한양행 퀴놀론 카르복실레이트 유도체의 제조방법
US20080139574A1 (en) 2006-11-30 2008-06-12 Cadila Healthcare Limited Novel quinoline derivatives
AU2012308582B2 (en) 2011-09-15 2016-11-24 Arizona Board Of Regents, A Body Corporate Of The State Of Arizona Acting For And On Behalf Of Arizona State University Therapeutic compounds
US10328040B2 (en) 2014-01-17 2019-06-25 Arizona Board Of Regents On Behalf Of Arizona State University Therapeutic methods
US10231947B2 (en) 2017-01-23 2019-03-19 Arizona Board Of Regents On Behalf Of Arizona State University Isochroman compounds and methods of use thereof
US10238655B2 (en) 2017-01-23 2019-03-26 Arizona Board Of Regents On Behalf Of Arizona State University Dihydroindene and tetrahydronaphthalene compounds
US10238626B2 (en) 2017-01-23 2019-03-26 Arizona Board Of Regents On Behalf Of Arizona State University Therapeutic compounds
JP7282332B2 (ja) * 2017-10-25 2023-05-29 学校法人順天堂 リアノジン受容体阻害薬
CN113968787A (zh) * 2020-07-24 2022-01-25 广东东阳光药业有限公司 一种制备5-氟-4-甲基-2-硝基苯甲酸的方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2103805C3 (de) * 1970-01-28 1980-03-20 Sumitomo Chemical Co., Ltd., Osaka (Japan) Verfahren zur Herstellung von N-substituierten 6,7-Methylendioxy-4chinolonen
DE2246503A1 (de) * 1972-09-22 1974-04-04 Boehringer Mannheim Gmbh 7,8-dimethylchinolon-3-carbonsaeurederivate
JPS604820B2 (ja) * 1979-02-26 1985-02-06 大塚製薬株式会社 キノリンカルボン酸誘導体
JPS5653656A (en) * 1979-10-05 1981-05-13 Tanabe Seiyaku Co Ltd Quinoline derivative and its preparation
DE3248507A1 (de) * 1982-12-29 1984-07-05 Bayer Ag, 5090 Leverkusen Mikrobizide mittel auf chinoloncarbonsaeure basis
DE3318145A1 (de) * 1983-05-18 1984-11-22 Bayer Ag, 5090 Leverkusen 7-amino-1-cyclopropyl-6,8-difluor-1,4-dihydro-4-oxo-3-chinolincarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
US4571396A (en) * 1984-04-16 1986-02-18 Warner-Lambert Company Antibacterial agents
US4623650A (en) * 1984-12-06 1986-11-18 Pfizer Inc. Antibiotic derivatives of 7-phenyl-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids

Also Published As

Publication number Publication date
US4762844A (en) 1988-08-09
PL145639B1 (en) 1988-10-31
FI854466A0 (fi) 1985-11-13
AU4917785A (en) 1986-05-22
FI854466A (fi) 1986-05-16
CS813285A2 (en) 1987-03-12
HUT40422A (en) 1986-12-28
ES548843A0 (es) 1986-11-16
JPS61122272A (ja) 1986-06-10
EP0181588A3 (de) 1989-02-01
EP0181588A2 (de) 1986-05-21
AU572702B2 (en) 1988-05-12
CA1260478A (en) 1989-09-26
KR860004026A (ko) 1986-06-16
BR8505734A (pt) 1986-08-12
DE3441788A1 (de) 1986-05-15
HU194178B (en) 1988-01-28
ES8700851A1 (es) 1986-11-16
CS252835B2 (en) 1987-10-15
PL256260A1 (en) 1986-12-30
KR870000784B1 (ko) 1987-04-18

Similar Documents

Publication Publication Date Title
ZA858733B (en) Alkyl-1-cyclopropyl,1,4-dihydro-4-oxo-3-quinolinecarboxylic acids,a process for their preparation and antibacterial agents containing these compounds
ZA854167B (en) 7-amino-1-cyclopropyl-6,8-dihalogeno-1,-dihydro-4-oxo-3-quinolinecarboxylic acids,process for their preparation and antibacterial agents containing them
IL76796A0 (en) 9-amino-1,2,3,4-tetrahydroacridin-1-ol and related compounds,a process for their preparation and their use as medicaments
ZA858163B (en) 9-amino-1,2,3,4-tetrahydroacridin-1-ol and related compounds,a process for their preparation and their use as medicaments
ZA816080B (en) 7-amino-1-cyclopropyl-4-oxo-1,4-dihydro-naphthyridine-3-carboxylic acids,processes for their preparation and antibacterial agents containing these compounds
CY1487A (en) 7-amino-1-cyclopropyl-6,8-difluoro-1,4-dihydro-4-oxo-3-quinotinecarboxylic acids,processes for their preparation and also antibacterial agents containing these substances
EP0159174A3 (en) Substituted naphthyridine-, quinoline- and benzoxazine- carboxylic acids as antibacterial agents and processes for their production
PT80349A (en) Process for the preparation of 1,4-dihydro-4-oxonaphthyridine derivatives and salts thereof and of antibacterial agents comprising the same
ZA841375B (en) Quinolone acids,processes for their preparation and antibacterial agents containing these compounds
HUT39479A (en) Process for preparing 4'-dechloro-rebeccamicin
GB2205830B (en) Process for the preparation of 1,2,5,6,9,10-hexabromocyclododecane
DE3567638D1 (en) 2,4-dichloro-3-alkyl-6-nitrophenols and process for their preparation
ZA873565B (en) New quinoline compounds and a process for the preparation thereof
PT81144A (en) Process for the preparation of antibacterial 2,4-dichloro-5-fluoro-benzoic acid
DE3260908D1 (en) Process for preparing o,o'-dithiodibenzoic acids
PT76012A (en) Process for preparing 1,1-alkanediol dicarboxilate linked antibacterial agents
GB8800425D0 (en) Process for preparing 4 4-dialkyl-2-azetidinones
GB8824694D0 (en) New isopolypeptides & process for preparation thereof
PT81086A (en) Histargin-related compounds a process for their preparation and their use as medicaments
PT79833A (en) Process for preparing novel n-phosphoryl- or n-thiophosphoryl-n'-s-triazinyl-formamidines
EP0186629A3 (en) Process for the preparation of 3,5-dialkyl-4-hydroxybenzoic acid
EP0232536A3 (en) Spirodiphosphoamidate type compounds and process for their preparation
DE3161077D1 (en) 2,4-diamino-5-sulfamoylbenzol-sulfonic acids and process for their preparation
IE840444L (en) Quinolonecarboxylic acids
PL245983A1 (en) Process for preparing 2,2-dibromo-haloacetphenones,especially 2,2-dibromo-2',4-dichloroacetphenone