ZA84958B - 3-(5-aminopentyl)-amino-1-benzazepin-2-one-1-alkanoic acids - Google Patents

3-(5-aminopentyl)-amino-1-benzazepin-2-one-1-alkanoic acids

Info

Publication number
ZA84958B
ZA84958B ZA84958A ZA84958A ZA84958B ZA 84958 B ZA84958 B ZA 84958B ZA 84958 A ZA84958 A ZA 84958A ZA 84958 A ZA84958 A ZA 84958A ZA 84958 B ZA84958 B ZA 84958B
Authority
ZA
South Africa
Prior art keywords
benzazepin
aminopentyl
amino
alkanoic acids
alkanoic
Prior art date
Application number
ZA84958A
Other languages
English (en)
Inventor
Jeffrey William Herber Watthey
Stephen K Boyer
Joseph Bach
Gottfried Sedelmeier
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of ZA84958B publication Critical patent/ZA84958B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16—Benzazepines; Hydrogenated benzazepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06086—Dipeptides with the first amino acid being basic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
ZA84958A 1983-02-10 1984-02-09 3-(5-aminopentyl)-amino-1-benzazepin-2-one-1-alkanoic acids ZA84958B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/465,695 US4473575A (en) 1982-07-19 1983-02-10 3-Amino-(1)-benzazepin-2-one-1-alkanoic acids

Publications (1)

Publication Number Publication Date
ZA84958B true ZA84958B (en) 1984-09-26

Family

ID=23848805

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA84958A ZA84958B (en) 1983-02-10 1984-02-09 3-(5-aminopentyl)-amino-1-benzazepin-2-one-1-alkanoic acids

Country Status (24)

Country Link
US (1) US4473575A (es)
EP (2) EP0119954B1 (es)
JP (2) JPS59172473A (es)
KR (1) KR900009023B1 (es)
AR (8) AR242564A1 (es)
AT (2) ATE50989T1 (es)
AU (1) AU574061B2 (es)
CA (2) CA1225397A (es)
CY (1) CY1674A (es)
DD (1) DD218359A5 (es)
DE (2) DE3480705D1 (es)
DK (2) DK171257B1 (es)
ES (10) ES8609261A1 (es)
FI (1) FI77857C (es)
GR (1) GR79809B (es)
HK (1) HK97592A (es)
HU (1) HU192394B (es)
IE (1) IE56858B1 (es)
IL (1) IL70881A (es)
NO (1) NO166232C (es)
NZ (1) NZ207091A (es)
PT (1) PT78075B (es)
SG (1) SG94992G (es)
ZA (1) ZA84958B (es)

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US4575503A (en) * 1983-02-10 1986-03-11 Ciba-Geigy Corporation 3-Amino-[1]-benzazepin-2-one-1-alkanoic acids
US4600534A (en) * 1984-02-06 1986-07-15 Ciba-Geigy Corporation Process and intermediates for manufacture of 3-(5-amino-1-carboxypentylamino)-tetrahydro-1-benzazepin-2-one-1-acetic acid
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US4918187A (en) * 1986-05-28 1990-04-17 Ciba-Geigy Corporation [2,5-Dihydro 5-phenyl-2-oxo-3-furanyl]amines
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Also Published As

Publication number Publication date
DK58284A (da) 1984-08-11
HU192394B (en) 1987-06-29
FI77857C (fi) 1989-05-10
AR243165A1 (es) 1993-07-30
FI840513A0 (fi) 1984-02-08
PT78075A (en) 1984-03-01
CA1225397A (en) 1987-08-11
AU574061B2 (en) 1988-06-30
PT78075B (en) 1986-06-11
ATE50989T1 (de) 1990-03-15
US4473575A (en) 1984-09-25
ES8609264A1 (es) 1986-09-01
AU2443084A (en) 1984-08-16
ES544127A0 (es) 1987-01-01
ES8705409A1 (es) 1987-05-01
ES8707216A1 (es) 1987-07-16
DK58184A (da) 1984-08-11
IL70881A (en) 1987-10-30
JPS59172473A (ja) 1984-09-29
GR79809B (es) 1984-10-31
AR243164A1 (es) 1993-07-30
ES544256A0 (es) 1987-05-01
AR243161A1 (es) 1993-07-30
AR243162A1 (es) 1993-07-30
ES544260A0 (es) 1986-09-01
DK171257B1 (da) 1996-08-12
IL70881A0 (en) 1984-05-31
JPS59172475A (ja) 1984-09-29
FI840513A (fi) 1984-08-11
EP0119955A3 (en) 1986-06-11
ES8702363A1 (es) 1987-01-01
ES8609263A1 (es) 1986-09-01
DK58184D0 (da) 1984-02-09
DE3481612D1 (de) 1990-04-19
NO166232B (no) 1991-03-11
AR243163A1 (es) 1993-07-30
DK58284D0 (da) 1984-02-09
ES8703859A1 (es) 1987-03-01
CY1674A (en) 1993-10-10
JPH0460108B2 (es) 1992-09-25
JPH0421665B2 (es) 1992-04-13
ES529595A0 (es) 1987-07-16
IE840302L (en) 1984-08-10
IE56858B1 (en) 1992-01-01
ES8609265A1 (es) 1986-09-01
DD218359A5 (de) 1985-02-06
ES544255A0 (es) 1986-09-01
EP0119955B1 (de) 1989-12-13
EP0119954A3 (en) 1986-06-11
EP0119954B1 (de) 1990-03-14
ES8700239A1 (es) 1986-10-16
HK97592A (en) 1992-12-11
ES544257A0 (es) 1986-09-01
KR840007722A (ko) 1984-12-10
ES544259A0 (es) 1986-10-16
EP0119954A2 (de) 1984-09-26
AR242190A1 (es) 1993-03-31
SG94992G (en) 1992-12-04
FI77857B (fi) 1989-01-31
NO166232C (no) 1991-06-19
AR242191A1 (es) 1993-03-31
ES544258A0 (es) 1986-09-01
ES8609261A1 (es) 1986-07-16
AR242564A1 (es) 1993-04-30
KR900009023B1 (ko) 1990-12-17
ES529594A0 (es) 1986-07-16
NO840487L (no) 1984-08-13
DE3480705D1 (de) 1990-01-18
CA1218993A (en) 1987-03-10
ATE48598T1 (de) 1989-12-15
ES8609262A1 (es) 1986-09-01
ES544254A0 (es) 1987-03-01
NZ207091A (en) 1985-11-08
EP0119955A2 (de) 1984-09-26

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