ZA838126B - 1-aroyl-5-oxo-2-pyrrolidinepropanoic acids and related esters - Google Patents

1-aroyl-5-oxo-2-pyrrolidinepropanoic acids and related esters

Info

Publication number
ZA838126B
ZA838126B ZA838126A ZA838126A ZA838126B ZA 838126 B ZA838126 B ZA 838126B ZA 838126 A ZA838126 A ZA 838126A ZA 838126 A ZA838126 A ZA 838126A ZA 838126 B ZA838126 B ZA 838126B
Authority
ZA
South Africa
Prior art keywords
aroyl
oxo
esters
amnesia
reversal
Prior art date
Application number
ZA838126A
Other languages
English (en)
Inventor
Donald Eugene Butler
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of ZA838126B publication Critical patent/ZA838126B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24Oxygen or sulfur atoms
    • C07D207/262-Pyrrolidones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA838126A 1982-11-15 1983-10-31 1-aroyl-5-oxo-2-pyrrolidinepropanoic acids and related esters ZA838126B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/441,335 US4452990A (en) 1982-11-15 1982-11-15 1-Aroyl-5-oxo-2-pyrrolidinepropanoic acids and related esters

Publications (1)

Publication Number Publication Date
ZA838126B true ZA838126B (en) 1985-06-26

Family

ID=23752490

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA838126A ZA838126B (en) 1982-11-15 1983-10-31 1-aroyl-5-oxo-2-pyrrolidinepropanoic acids and related esters

Country Status (20)

Country Link
US (1) US4452990A (pt)
EP (1) EP0110575B1 (pt)
JP (1) JPS59101461A (pt)
KR (1) KR900005018B1 (pt)
AT (1) ATE27272T1 (pt)
AU (1) AU557068B2 (pt)
CA (1) CA1215977A (pt)
DE (1) DE3371628D1 (pt)
DK (1) DK519783D0 (pt)
ES (1) ES8600238A1 (pt)
FI (1) FI77443C (pt)
GR (1) GR78737B (pt)
HU (1) HU190916B (pt)
IE (1) IE56126B1 (pt)
IL (1) IL70082A (pt)
NO (1) NO161491C (pt)
NZ (1) NZ206256A (pt)
PH (1) PH20393A (pt)
PT (1) PT77653B (pt)
ZA (1) ZA838126B (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4760083A (en) * 1986-04-10 1988-07-26 E. I. Dupont De Nemours & Company 3,3-disubstituted indolines
US5173489A (en) * 1986-04-10 1992-12-22 The Dupont Merck Pharmaceutical Co. α,α-disubstituted aromatics and heteroaromatics as cognition enhancers
US4876259A (en) * 1987-01-05 1989-10-24 E. I. Du Pont De Nemours And Company 3,3-disubstituted indolines
US5021439A (en) * 1988-10-31 1991-06-04 Takeda Chemical Industries, Ltd. Cerebral function ameliorating agents related to Tan-950 A
AT391692B (de) * 1989-04-24 1990-11-12 Fleischhacker Wilhelm Dr Enantiomerenreine, in position 1 alkylierte 5-oxo-2-pyrrolidinpropansaeuren und deren ester, deren herstellung und verwendung

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS535158A (en) * 1976-07-05 1978-01-18 Teijin Ltd Preparation of optical active alpha-alkylvenzylalcohol and its intermediates

Also Published As

Publication number Publication date
US4452990A (en) 1984-06-05
PT77653A (en) 1983-12-01
PH20393A (en) 1986-12-12
NO834149L (no) 1984-05-16
ES527241A0 (es) 1985-04-16
CA1215977A (en) 1986-12-30
IL70082A (en) 1987-07-31
GR78737B (pt) 1984-10-02
KR900005018B1 (ko) 1990-07-18
IE56126B1 (en) 1991-04-24
EP0110575B1 (en) 1987-05-20
HU190916B (en) 1986-12-28
EP0110575A1 (en) 1984-06-13
AU2087183A (en) 1984-05-24
ES8600238A1 (es) 1985-04-16
IE832475L (en) 1984-05-15
DK519783D0 (da) 1983-11-14
JPS59101461A (ja) 1984-06-12
FI77443B (fi) 1988-11-30
FI834136A0 (fi) 1983-11-11
NO161491B (no) 1989-05-16
DE3371628D1 (en) 1987-06-25
NZ206256A (en) 1985-09-13
FI834136A (fi) 1984-05-16
FI77443C (fi) 1989-03-10
AU557068B2 (en) 1986-12-04
IL70082A0 (en) 1984-01-31
KR840006622A (ko) 1984-12-01
ATE27272T1 (de) 1987-06-15
PT77653B (en) 1986-04-17
NO161491C (no) 1989-08-23

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