ATE35538T1 - (substituierte phenyl)-5-oxo-2pyrrolidinpropions|uren, verfahren zur herstellung dieser verbindungen und diese verbindungen enthaltende pharmazeutische zusammensetzungen. - Google Patents

(substituierte phenyl)-5-oxo-2pyrrolidinpropions|uren, verfahren zur herstellung dieser verbindungen und diese verbindungen enthaltende pharmazeutische zusammensetzungen.

Info

Publication number
ATE35538T1
ATE35538T1 AT85302949T AT85302949T ATE35538T1 AT E35538 T1 ATE35538 T1 AT E35538T1 AT 85302949 T AT85302949 T AT 85302949T AT 85302949 T AT85302949 T AT 85302949T AT E35538 T1 ATE35538 T1 AT E35538T1
Authority
AT
Austria
Prior art keywords
compounds
radical
pharmaceutical compositions
ures
oxo
Prior art date
Application number
AT85302949T
Other languages
English (en)
Inventor
Donald E Butler
Anthony J Thomas
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Application granted granted Critical
Publication of ATE35538T1 publication Critical patent/ATE35538T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Closures For Containers (AREA)
AT85302949T 1984-05-07 1985-04-26 (substituierte phenyl)-5-oxo-2pyrrolidinpropions|uren, verfahren zur herstellung dieser verbindungen und diese verbindungen enthaltende pharmazeutische zusammensetzungen. ATE35538T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/607,376 US4584313A (en) 1984-05-07 1984-05-07 (Substituted-phenyl)-5-oxo-2-pyrrolidinepropanoic acids and esters thereof, and use for reversing electroconvulsive shock-induced amnesia
EP85302949A EP0164853B1 (de) 1984-05-07 1985-04-26 (Substituierte Phenyl)-5-oxo-2-pyrrolidinpropionsäuren, Verfahren zur Herstellung dieser Verbindungen und diese Verbindungen enthaltende pharmazeutische Zusammensetzungen

Publications (1)

Publication Number Publication Date
ATE35538T1 true ATE35538T1 (de) 1988-07-15

Family

ID=24431998

Family Applications (1)

Application Number Title Priority Date Filing Date
AT85302949T ATE35538T1 (de) 1984-05-07 1985-04-26 (substituierte phenyl)-5-oxo-2pyrrolidinpropions|uren, verfahren zur herstellung dieser verbindungen und diese verbindungen enthaltende pharmazeutische zusammensetzungen.

Country Status (10)

Country Link
US (1) US4584313A (de)
EP (1) EP0164853B1 (de)
JP (1) JPS60239463A (de)
AT (1) ATE35538T1 (de)
AU (1) AU566359B2 (de)
CA (1) CA1235706A (de)
DE (1) DE3563621D1 (de)
DK (1) DK201385A (de)
ES (1) ES8702889A1 (de)
ZA (1) ZA852875B (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5665754A (en) * 1993-09-20 1997-09-09 Glaxo Wellcome Inc. Substituted pyrrolidines
CN107188808A (zh) * 2017-05-22 2017-09-22 江苏斯威森生物医药工程研究中心有限公司 一种4‑氨基‑3‑苯基丁酸盐酸盐的合成方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2413935A1 (de) * 1974-03-20 1975-10-16 Schering Ag 4-(polyalkoxy-phenyl)-2-pyrrolidone
AU518986B2 (en) * 1977-10-11 1981-10-29 Takeda Chemical Industries Ltd. Lactams

Also Published As

Publication number Publication date
DK201385D0 (da) 1985-05-06
EP0164853A1 (de) 1985-12-18
ES8702889A1 (es) 1987-01-16
EP0164853B1 (de) 1988-07-06
CA1235706A (en) 1988-04-26
ES542811A0 (es) 1987-01-16
ZA852875B (en) 1986-11-26
US4584313A (en) 1986-04-22
AU566359B2 (en) 1987-10-15
DK201385A (da) 1985-11-08
DE3563621D1 (en) 1988-08-11
AU4134185A (en) 1985-11-14
JPS60239463A (ja) 1985-11-28

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee