IL70082A - Pharmaceutical compositions comprising 1-aroyl-5-oxo-2-pyrrolidinopropanoic acids and salts and esters thereof,certain such compounds and their preparation - Google Patents

Pharmaceutical compositions comprising 1-aroyl-5-oxo-2-pyrrolidinopropanoic acids and salts and esters thereof,certain such compounds and their preparation

Info

Publication number
IL70082A
IL70082A IL70082A IL7008283A IL70082A IL 70082 A IL70082 A IL 70082A IL 70082 A IL70082 A IL 70082A IL 7008283 A IL7008283 A IL 7008283A IL 70082 A IL70082 A IL 70082A
Authority
IL
Israel
Prior art keywords
esters
salts
compounds
aroyl
oxo
Prior art date
Application number
IL70082A
Other languages
English (en)
Other versions
IL70082A0 (en
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of IL70082A0 publication Critical patent/IL70082A0/xx
Publication of IL70082A publication Critical patent/IL70082A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL70082A 1982-11-15 1983-10-28 Pharmaceutical compositions comprising 1-aroyl-5-oxo-2-pyrrolidinopropanoic acids and salts and esters thereof,certain such compounds and their preparation IL70082A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/441,335 US4452990A (en) 1982-11-15 1982-11-15 1-Aroyl-5-oxo-2-pyrrolidinepropanoic acids and related esters

Publications (2)

Publication Number Publication Date
IL70082A0 IL70082A0 (en) 1984-01-31
IL70082A true IL70082A (en) 1987-07-31

Family

ID=23752490

Family Applications (1)

Application Number Title Priority Date Filing Date
IL70082A IL70082A (en) 1982-11-15 1983-10-28 Pharmaceutical compositions comprising 1-aroyl-5-oxo-2-pyrrolidinopropanoic acids and salts and esters thereof,certain such compounds and their preparation

Country Status (20)

Country Link
US (1) US4452990A (xx)
EP (1) EP0110575B1 (xx)
JP (1) JPS59101461A (xx)
KR (1) KR900005018B1 (xx)
AT (1) ATE27272T1 (xx)
AU (1) AU557068B2 (xx)
CA (1) CA1215977A (xx)
DE (1) DE3371628D1 (xx)
DK (1) DK519783D0 (xx)
ES (1) ES527241A0 (xx)
FI (1) FI77443C (xx)
GR (1) GR78737B (xx)
HU (1) HU190916B (xx)
IE (1) IE56126B1 (xx)
IL (1) IL70082A (xx)
NO (1) NO161491C (xx)
NZ (1) NZ206256A (xx)
PH (1) PH20393A (xx)
PT (1) PT77653B (xx)
ZA (1) ZA838126B (xx)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4760083A (en) * 1986-04-10 1988-07-26 E. I. Dupont De Nemours & Company 3,3-disubstituted indolines
US5173489A (en) * 1986-04-10 1992-12-22 The Dupont Merck Pharmaceutical Co. α,α-disubstituted aromatics and heteroaromatics as cognition enhancers
US4876259A (en) * 1987-01-05 1989-10-24 E. I. Du Pont De Nemours And Company 3,3-disubstituted indolines
EP0367393A3 (en) * 1988-10-31 1991-03-27 Takeda Chemical Industries, Ltd. New heterocyclic compounds, production and use thereof
AT391692B (de) * 1989-04-24 1990-11-12 Fleischhacker Wilhelm Dr Enantiomerenreine, in position 1 alkylierte 5-oxo-2-pyrrolidinpropansaeuren und deren ester, deren herstellung und verwendung

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS535158A (en) * 1976-07-05 1978-01-18 Teijin Ltd Preparation of optical active alpha-alkylvenzylalcohol and its intermediates

Also Published As

Publication number Publication date
AU557068B2 (en) 1986-12-04
DK519783D0 (da) 1983-11-14
HU190916B (en) 1986-12-28
FI77443C (fi) 1989-03-10
NO834149L (no) 1984-05-16
US4452990A (en) 1984-06-05
CA1215977A (en) 1986-12-30
ZA838126B (en) 1985-06-26
IE56126B1 (en) 1991-04-24
NO161491B (no) 1989-05-16
NO161491C (no) 1989-08-23
FI77443B (fi) 1988-11-30
ES8600238A1 (es) 1985-04-16
PH20393A (en) 1986-12-12
ATE27272T1 (de) 1987-06-15
KR840006622A (ko) 1984-12-01
IE832475L (en) 1984-05-15
PT77653B (en) 1986-04-17
FI834136A0 (fi) 1983-11-11
KR900005018B1 (ko) 1990-07-18
FI834136A (fi) 1984-05-16
JPS59101461A (ja) 1984-06-12
GR78737B (xx) 1984-10-02
EP0110575A1 (en) 1984-06-13
AU2087183A (en) 1984-05-24
NZ206256A (en) 1985-09-13
EP0110575B1 (en) 1987-05-20
PT77653A (en) 1983-12-01
ES527241A0 (es) 1985-04-16
DE3371628D1 (en) 1987-06-25
IL70082A0 (en) 1984-01-31

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