ZA821901B - Bis-esters of 1,1-alkanediols with 6-beta-hydroxymethylpenicillanic acid 1,1-dioxide and beta-lactam antibiotics - Google Patents

Bis-esters of 1,1-alkanediols with 6-beta-hydroxymethylpenicillanic acid 1,1-dioxide and beta-lactam antibiotics

Info

Publication number
ZA821901B
ZA821901B ZA821901A ZA821901A ZA821901B ZA 821901 B ZA821901 B ZA 821901B ZA 821901 A ZA821901 A ZA 821901A ZA 821901 A ZA821901 A ZA 821901A ZA 821901 B ZA821901 B ZA 821901B
Authority
ZA
South Africa
Prior art keywords
beta
esters
dioxide
alkanediols
hydroxymethyl
Prior art date
Application number
ZA821901A
Other languages
English (en)
Inventor
Michael Stephen Kellogg
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of ZA821901B publication Critical patent/ZA821901B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D499/00Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Cephalosporin Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA821901A 1981-03-23 1982-03-22 Bis-esters of 1,1-alkanediols with 6-beta-hydroxymethylpenicillanic acid 1,1-dioxide and beta-lactam antibiotics ZA821901B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/246,505 US4342768A (en) 1979-10-22 1981-03-23 Bis-esters of 1,1-alkanediols with 6-beta-hydroxymethylpenicillanic acid 1,1-dioxide and beta-lactam antibiotics

Publications (1)

Publication Number Publication Date
ZA821901B true ZA821901B (en) 1983-01-26

Family

ID=22930958

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA821901A ZA821901B (en) 1981-03-23 1982-03-22 Bis-esters of 1,1-alkanediols with 6-beta-hydroxymethylpenicillanic acid 1,1-dioxide and beta-lactam antibiotics

Country Status (26)

Country Link
US (1) US4342768A (de)
EP (1) EP0061313B1 (de)
JP (1) JPS57169492A (de)
KR (1) KR860000425B1 (de)
AT (1) ATE11291T1 (de)
AU (1) AU527895B2 (de)
CA (1) CA1201709A (de)
CS (1) CS228921B2 (de)
DD (1) DD203723A5 (de)
DE (1) DE3261898D1 (de)
DK (1) DK126982A (de)
ES (1) ES8305769A1 (de)
FI (1) FI74285C (de)
GR (1) GR76107B (de)
GT (1) GT198274394A (de)
HU (1) HU186487B (de)
IE (1) IE52812B1 (de)
IL (1) IL65306A (de)
NO (1) NO820897L (de)
NZ (1) NZ200068A (de)
PH (1) PH18040A (de)
PL (1) PL130110B1 (de)
PT (1) PT74624B (de)
SU (1) SU1122230A3 (de)
YU (1) YU61882A (de)
ZA (1) ZA821901B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4540689A (en) * 1981-09-22 1985-09-10 Kureha Kagaku Kogyo Kabushiki Kaisha Penicillin derivative
US4452796A (en) * 1982-06-14 1984-06-05 Pfizer Inc. 6-Aminoalkylpenicillanic acid 1,1-dioxides as beta-lactamase inhibitors
EP0084730A1 (de) * 1982-01-22 1983-08-03 Beecham Group Plc Ester von Penicillinderivaten mit Beta-Lactamase-Inhibitoren, ihre Herstellung und ihre Verwendung
FR2520362B1 (fr) * 1982-01-26 1986-04-11 Leo Pharm Prod Ltd Nouveaux composes de type b-lactame, y compris leurs sels formes avec des acides ou des bases acceptables en pharmacie, procedes pour produire ces composes, medicaments les contenant et leur utilisation pour combattre les maladies infectieuses
US4462934A (en) * 1983-03-31 1984-07-31 Pfizer Inc. Bis-esters of dicarboxylic acids with amoxicillin and certain hydroxymethylpenicillanate 1,1-dioxides
US4536393A (en) * 1983-06-06 1985-08-20 Pfizer Inc. 6-(Aminomethyl)penicillanic acid 1,1-dioxide esters and intermediates therefor
US4503040A (en) * 1984-02-27 1985-03-05 Pfizer Inc. 6-(Aminoacyloxymethyl)penicillanic acid 1,1-dioxides as beta-lactamase inhibitors
US4591459A (en) * 1984-12-03 1986-05-27 Pfizer Inc. Intermediates for 6-(aminoacyloxymethyl) penicillanic acid 1,1-dioxides
US4675186A (en) 1985-04-18 1987-06-23 Pfizer Inc. 6-(1-acyl-1-hydroxymethyl)penicillanic acid derivatives
US4762921A (en) * 1985-04-18 1988-08-09 Pfizer Inc. 6-(1-acyl-1-hydroxymethyl)penicillanic acid derivatives
JPS63144296U (de) * 1987-03-12 1988-09-22
CN108107120B (zh) * 2017-12-12 2020-12-01 山东鑫泉医药有限公司 采用高效液相法测定中间产物6,6-二溴青霉烷酸的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4207323A (en) * 1975-11-21 1980-06-10 Merck & Co., Inc. 6-Substituted methyl penicillins, derivatives and analogues thereof
IE49881B1 (en) 1979-02-13 1986-01-08 Leo Pharm Prod Ltd B-lactam intermediates
US4244951A (en) * 1979-05-16 1981-01-13 Pfizer Inc. Bis-esters of methanediol with penicillins and penicillanic acid 1,1-dioxide

Also Published As

Publication number Publication date
HU186487B (en) 1985-08-28
FI74285B (fi) 1987-09-30
PH18040A (en) 1985-03-08
GR76107B (de) 1984-08-03
PL235576A1 (en) 1983-03-14
DE3261898D1 (en) 1985-02-28
ATE11291T1 (de) 1985-02-15
DD203723A5 (de) 1983-11-02
IL65306A0 (en) 1982-05-31
ES510656A0 (es) 1983-04-16
DK126982A (da) 1982-09-24
PT74624A (en) 1982-04-01
EP0061313A2 (de) 1982-09-29
AU527895B2 (en) 1983-03-31
GT198274394A (es) 1983-09-08
PL130110B1 (en) 1984-07-31
AU8176182A (en) 1982-11-04
IE820656L (en) 1982-09-23
NZ200068A (en) 1985-08-16
FI74285C (fi) 1988-01-11
IL65306A (en) 1986-02-28
FI820992L (fi) 1982-09-24
SU1122230A3 (ru) 1984-10-30
EP0061313A3 (en) 1982-12-08
PT74624B (en) 1984-11-26
US4342768A (en) 1982-08-03
CA1201709A (en) 1986-03-11
CS228921B2 (en) 1984-05-14
IE52812B1 (en) 1988-03-16
KR860000425B1 (ko) 1986-04-19
JPS6325593B2 (de) 1988-05-26
YU61882A (en) 1985-03-20
KR830009110A (ko) 1983-12-17
NO820897L (no) 1982-09-24
ES8305769A1 (es) 1983-04-16
JPS57169492A (en) 1982-10-19
EP0061313B1 (de) 1985-01-16

Similar Documents

Publication Publication Date Title
ES8104300A1 (es) Un procedimiento para la preparacion de nuevos bis-esteres de metanodiol.
DE3261898D1 (en) Bis-esters of 1,1-alkanediols with 6-beta-hydroxymethylpenicillanic acid 1,1-dioxide and beta-lactam antibiotics
DE3265082D1 (en) Beta-lactamase inhibiting 2-beta-substituted-2-alpha-methyl-(5r) penam-3-alpha-carboxylic acid 1,1-dioxides and intermediates therefor
GB2045755B (en) Process and intermediates for penicillanic acid 1,1-dioxide and esters thereof
IE820342L (en) Penicillins
JPS5690088A (en) Novel cephalosporin analog compound
ATE136306T1 (de) Solvate von einem beta-lactam-antibiotikum
IE822278L (en) Anti bacterial esters of beta-lactams
ZA80646B (en) Process and intermediates for penicillanic acid,1,1-dioxide and esters thereof
IE810102L (en) Penicillin compounds
PT83311A (en) Process for the preparation of 6-amino penicillanic acid 1,1-dioxide by oxidation of this acid
HUT34203A (en) Process for producing 6-/amino-methyl/-penicillanic acid-1,1-dioxide and derivatives
ZA793092B (en) Combinations of penicillanic acid 1,1-dioxide with 7-(d-2-(4-ethyl-piperazin-2,3-dione-1-carboxamido)-2-(4-hydroxyphenyl)acetamido)-3-((1-methyl-5-tetrazolyl)thiomethyl)-3-desacetoxymethylcephalosporanic acid
PH19472A (en) Process and intermediates for penicillanic acid 1,1-dioxide and esters thereof