ZA821001B - New medicaments derived from 3-hydroxy dodecahydro benz(e)inden-7-ome,products derived from 3-hydroxy dodecahydro benz(e)inden-7-one and the process for their preparation - Google Patents

New medicaments derived from 3-hydroxy dodecahydro benz(e)inden-7-ome,products derived from 3-hydroxy dodecahydro benz(e)inden-7-one and the process for their preparation

Info

Publication number
ZA821001B
ZA821001B ZA821001A ZA821001A ZA821001B ZA 821001 B ZA821001 B ZA 821001B ZA 821001 A ZA821001 A ZA 821001A ZA 821001 A ZA821001 A ZA 821001A ZA 821001 B ZA821001 B ZA 821001B
Authority
ZA
South Africa
Prior art keywords
carbon atoms
dodecahydro
inden
benz
hydroxy
Prior art date
Application number
ZA821001A
Other languages
English (en)
Inventor
Marie Madeleine Bouton
Andre Pierdet
Jean Jacques
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of ZA821001B publication Critical patent/ZA821001B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79Acids; Esters
    • C07D213/80Acids; Esters in position 3
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/385Saturated compounds containing a keto group being part of a ring
    • C07C49/487Saturated compounds containing a keto group being part of a ring containing hydroxy groups
    • C07C49/507Saturated compounds containing a keto group being part of a ring containing hydroxy groups polycyclic
    • C07C49/513Saturated compounds containing a keto group being part of a ring containing hydroxy groups polycyclic a keto group being part of a condensed ring system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/70Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with ring systems containing two or more relevant rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/72Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 spiro-condensed with carbocyclic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00Systems containing at least three condensed rings
    • C07C2603/02Ortho- or ortho- and peri-condensed systems
    • C07C2603/04Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/06Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
    • C07C2603/10Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
    • C07C2603/12Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
    • C07C2603/16Benz[e]indenes; Hydrogenated benz[e]indenes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyridine Compounds (AREA)
  • Cosmetics (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Steroid Compounds (AREA)
ZA821001A 1981-02-23 1982-02-16 New medicaments derived from 3-hydroxy dodecahydro benz(e)inden-7-ome,products derived from 3-hydroxy dodecahydro benz(e)inden-7-one and the process for their preparation ZA821001B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8103520A FR2500441A1 (fr) 1981-02-23 1981-02-23 Nouveaux medicaments derives de la 3-hydroxy dodecahydro benz (e) inden-7-one, produits derives de la 3-hydroxy dodecahydro benz (e) inden-7-one et leur procede de preparation

Publications (1)

Publication Number Publication Date
ZA821001B true ZA821001B (en) 1983-01-26

Family

ID=9255514

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA821001A ZA821001B (en) 1981-02-23 1982-02-16 New medicaments derived from 3-hydroxy dodecahydro benz(e)inden-7-ome,products derived from 3-hydroxy dodecahydro benz(e)inden-7-one and the process for their preparation

Country Status (11)

Country Link
US (5) US4466971A (da)
EP (1) EP0059146B1 (da)
JP (2) JPS57156430A (da)
AT (1) ATE15761T1 (da)
AU (1) AU547375B2 (da)
CA (1) CA1195982A (da)
DE (1) DE3266460D1 (da)
DK (1) DK167113B1 (da)
FR (1) FR2500441A1 (da)
IE (1) IE52327B1 (da)
ZA (1) ZA821001B (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2500441A1 (fr) * 1981-02-23 1982-08-27 Roussel Uclaf Nouveaux medicaments derives de la 3-hydroxy dodecahydro benz (e) inden-7-one, produits derives de la 3-hydroxy dodecahydro benz (e) inden-7-one et leur procede de preparation
TW224048B (da) * 1992-03-30 1994-05-21 Hoechst Roussel Pharma
AU7558900A (en) * 1999-10-14 2001-04-23 Kaken Pharmaceutical Co., Ltd. Tetrahydroquinoline derivatives

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1359675A (fr) * 1963-01-14 1964-04-30 Roussel Uclaf Nouveaux composés tricycliques et procédé de préparation
US3499912A (en) * 1963-11-06 1970-03-10 Hoffmann La Roche Process for the preparation of 5-oxo-11alpha-hydroxy - 3,5 - seco-a-nor-pregnan-3-oic acid - 3,11 lactones and derivatives thereof
US3956316A (en) * 1964-09-29 1976-05-11 Hoffmann-La Roche Inc. 11-Substituted-desA-pregnanes and derivatives thereof
US3412107A (en) * 1964-09-29 1968-11-19 Hoffmann La Roche 11-hydroxy-5-oxo-3, 5-seco-a-nor-androstan-3-oic acid 3, 11-lactones
CH558343A (de) * 1965-03-25 1975-01-31 Hoffmann La Roche Verfahren zur herstellung von 9(beta),10(alpha)-steroiden.
US3574688A (en) * 1966-03-22 1971-04-13 Roussel Uclaf Unsaturated 2-oxa steroid derivatives and process for their preparation
US3496199A (en) * 1968-06-17 1970-02-17 Hoffmann La Roche Process for the preparation of 9beta,10alpha-steroids
US3984473A (en) * 1968-10-04 1976-10-05 Hoffmann-La Roche Inc. Stereospecific total steroidal synthesis via substituted C/D-trans indanones
US3984474A (en) * 1975-05-30 1976-10-05 E. R. Squibb & Sons, Inc. 4,5-Secoandrostanes
JPS5538316A (en) * 1978-09-08 1980-03-17 Takeda Chem Ind Ltd Intermediate for synthesis of steroid and its preparation
CA1195997A (en) * 1979-02-23 1985-10-29 Andor Furst Dea-steroids
FR2500441A1 (fr) * 1981-02-23 1982-08-27 Roussel Uclaf Nouveaux medicaments derives de la 3-hydroxy dodecahydro benz (e) inden-7-one, produits derives de la 3-hydroxy dodecahydro benz (e) inden-7-one et leur procede de preparation

Also Published As

Publication number Publication date
EP0059146B1 (fr) 1985-09-25
FR2500441A1 (fr) 1982-08-27
EP0059146A1 (fr) 1982-09-01
FR2500441B1 (da) 1984-10-19
US5158981A (en) 1992-10-27
CA1195982A (fr) 1985-10-29
AU547375B2 (en) 1985-10-17
DK75282A (da) 1982-08-24
JPH02243646A (ja) 1990-09-27
JPH0420893B2 (da) 1992-04-07
DE3266460D1 (en) 1985-10-31
JPS57156430A (en) 1982-09-27
DK167113B1 (da) 1993-08-30
US4849454A (en) 1989-07-18
ATE15761T1 (de) 1985-10-15
US4466971A (en) 1984-08-21
IE820379L (en) 1982-08-23
JPH0466855B2 (da) 1992-10-26
IE52327B1 (en) 1987-09-16
US4927975A (en) 1990-05-22
AU8069982A (en) 1982-09-02
US4607054A (en) 1986-08-19

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