JPS57156430A - Compounds and novel drugs derived from 3-hydroxydodecahydrobenzo(e)indene-7-one manufacture - Google Patents

Compounds and novel drugs derived from 3-hydroxydodecahydrobenzo(e)indene-7-one manufacture

Info

Publication number
JPS57156430A
JPS57156430A JP57026928A JP2692882A JPS57156430A JP S57156430 A JPS57156430 A JP S57156430A JP 57026928 A JP57026928 A JP 57026928A JP 2692882 A JP2692882 A JP 2692882A JP S57156430 A JPS57156430 A JP S57156430A
Authority
JP
Japan
Prior art keywords
carbon atoms
alkyl
hydrogen
group
hydroxydodecahydrobenzo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP57026928A
Other languages
English (en)
Other versions
JPH0420893B2 (ja
Inventor
Madoreenu Buuton Marii
Jiyatsuku Jiyan
Pierude Andore
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Publication of JPS57156430A publication Critical patent/JPS57156430A/ja
Publication of JPH0420893B2 publication Critical patent/JPH0420893B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/80—Acids; Esters in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/385—Saturated compounds containing a keto group being part of a ring
    • C07C49/487—Saturated compounds containing a keto group being part of a ring containing hydroxy groups
    • C07C49/507—Saturated compounds containing a keto group being part of a ring containing hydroxy groups polycyclic
    • C07C49/513—Saturated compounds containing a keto group being part of a ring containing hydroxy groups polycyclic a keto group being part of a condensed ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/70—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with ring systems containing two or more relevant rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/72—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 spiro-condensed with carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/02—Ortho- or ortho- and peri-condensed systems
    • C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
    • C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
    • C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
    • C07C2603/16—Benz[e]indenes; Hydrogenated benz[e]indenes
JP57026928A 1981-02-23 1982-02-23 Compounds and novel drugs derived from 3-hydroxydodecahydrobenzo(e)indene-7-one manufacture Granted JPS57156430A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8103520A FR2500441A1 (fr) 1981-02-23 1981-02-23 Nouveaux medicaments derives de la 3-hydroxy dodecahydro benz (e) inden-7-one, produits derives de la 3-hydroxy dodecahydro benz (e) inden-7-one et leur procede de preparation

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2028621A Division JPH02243646A (ja) 1981-02-23 1990-02-09 ３―ヒドロキシドデカヒドロベンゾ（ｅ）インデン―７―オンから誘導される化合物及びこれらの製造法

Publications (2)

Publication Number Publication Date
JPS57156430A true JPS57156430A (en) 1982-09-27
JPH0420893B2 JPH0420893B2 (ja) 1992-04-07

Family

ID=9255514

Family Applications (2)

Application Number Title Priority Date Filing Date
JP57026928A Granted JPS57156430A (en) 1981-02-23 1982-02-23 Compounds and novel drugs derived from 3-hydroxydodecahydrobenzo(e)indene-7-one manufacture
JP2028621A Granted JPH02243646A (ja) 1981-02-23 1990-02-09 ３―ヒドロキシドデカヒドロベンゾ（ｅ）インデン―７―オンから誘導される化合物及びこれらの製造法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2028621A Granted JPH02243646A (ja) 1981-02-23 1990-02-09 ３―ヒドロキシドデカヒドロベンゾ（ｅ）インデン―７―オンから誘導される化合物及びこれらの製造法

Country Status (11)

Country Link
US (5) US4466971A (ja)
EP (1) EP0059146B1 (ja)
JP (2) JPS57156430A (ja)
AT (1) ATE15761T1 (ja)
AU (1) AU547375B2 (ja)
CA (1) CA1195982A (ja)
DE (1) DE3266460D1 (ja)
DK (1) DK167113B1 (ja)
FR (1) FR2500441A1 (ja)
IE (1) IE52327B1 (ja)
ZA (1) ZA821001B (ja)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2500441A1 (fr) * 1981-02-23 1982-08-27 Roussel Uclaf Nouveaux medicaments derives de la 3-hydroxy dodecahydro benz (e) inden-7-one, produits derives de la 3-hydroxy dodecahydro benz (e) inden-7-one et leur procede de preparation
TW224048B (ja) * 1992-03-30 1994-05-21 Hoechst Roussel Pharma
KR100731566B1 (ko) * 1999-10-14 2007-06-22 가켄 세야쿠 가부시키가이샤 테트라히드로퀴놀린 유도체

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3984473A (en) * 1968-10-04 1976-10-05 Hoffmann-La Roche Inc. Stereospecific total steroidal synthesis via substituted C/D-trans indanones

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1359675A (fr) * 1963-01-14 1964-04-30 Roussel Uclaf Nouveaux composés tricycliques et procédé de préparation
US3499912A (en) * 1963-11-06 1970-03-10 Hoffmann La Roche Process for the preparation of 5-oxo-11alpha-hydroxy - 3,5 - seco-a-nor-pregnan-3-oic acid - 3,11 lactones and derivatives thereof
US3956316A (en) * 1964-09-29 1976-05-11 Hoffmann-La Roche Inc. 11-Substituted-desA-pregnanes and derivatives thereof
US3412107A (en) * 1964-09-29 1968-11-19 Hoffmann La Roche 11-hydroxy-5-oxo-3, 5-seco-a-nor-androstan-3-oic acid 3, 11-lactones
CH558343A (de) * 1965-03-25 1975-01-31 Hoffmann La Roche Verfahren zur herstellung von 9(beta),10(alpha)-steroiden.
US3574688A (en) * 1966-03-22 1971-04-13 Roussel Uclaf Unsaturated 2-oxa steroid derivatives and process for their preparation
US3496199A (en) * 1968-06-17 1970-02-17 Hoffmann La Roche Process for the preparation of 9beta,10alpha-steroids
US3984474A (en) * 1975-05-30 1976-10-05 E. R. Squibb & Sons, Inc. 4,5-Secoandrostanes
JPS5538316A (en) * 1978-09-08 1980-03-17 Takeda Chem Ind Ltd Intermediate for synthesis of steroid and its preparation
CA1195997A (en) * 1979-02-23 1985-10-29 Andor Furst Dea-steroids
FR2500441A1 (fr) * 1981-02-23 1982-08-27 Roussel Uclaf Nouveaux medicaments derives de la 3-hydroxy dodecahydro benz (e) inden-7-one, produits derives de la 3-hydroxy dodecahydro benz (e) inden-7-one et leur procede de preparation

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3984473A (en) * 1968-10-04 1976-10-05 Hoffmann-La Roche Inc. Stereospecific total steroidal synthesis via substituted C/D-trans indanones

Also Published As

Publication number Publication date
US4849454A (en) 1989-07-18
EP0059146B1 (fr) 1985-09-25
ATE15761T1 (de) 1985-10-15
US4927975A (en) 1990-05-22
DK75282A (da) 1982-08-24
IE820379L (en) 1982-08-23
JPH02243646A (ja) 1990-09-27
DE3266460D1 (en) 1985-10-31
FR2500441A1 (fr) 1982-08-27
FR2500441B1 (ja) 1984-10-19
US4607054A (en) 1986-08-19
AU547375B2 (en) 1985-10-17
CA1195982A (fr) 1985-10-29
JPH0420893B2 (ja) 1992-04-07
US5158981A (en) 1992-10-27
ZA821001B (en) 1983-01-26
EP0059146A1 (fr) 1982-09-01
US4466971A (en) 1984-08-21
DK167113B1 (da) 1993-08-30
IE52327B1 (en) 1987-09-16
JPH0466855B2 (ja) 1992-10-26
AU8069982A (en) 1982-09-02

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