DK75282A - Fremgangsmaade til fremstilling af 3-hydroxydodecahydrobenz (e) inden-7-onderivater - Google Patents
Fremgangsmaade til fremstilling af 3-hydroxydodecahydrobenz (e) inden-7-onderivater Download PDFInfo
- Publication number
- DK75282A DK75282A DK75282A DK75282A DK75282A DK 75282 A DK75282 A DK 75282A DK 75282 A DK75282 A DK 75282A DK 75282 A DK75282 A DK 75282A DK 75282 A DK75282 A DK 75282A
- Authority
- DK
- Denmark
- Prior art keywords
- carbon atoms
- alkyl
- hydrogen
- group
- heteroatom
- Prior art date
Links
- 239000000126 substance Substances 0.000 title 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 8
- 125000000217 alkyl group Chemical group 0.000 abstract 5
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
- 125000003342 alkenyl group Chemical group 0.000 abstract 2
- 125000000304 alkynyl group Chemical group 0.000 abstract 2
- 125000005842 heteroatom Chemical group 0.000 abstract 2
- 241001465754 Metazoa Species 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 230000002280 anti-androgenic effect Effects 0.000 abstract 1
- 150000001732 carboxylic acid derivatives Chemical class 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 125000002485 formyl group Chemical group [H]C(*)=O 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 230000003000 nontoxic effect Effects 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C07D213/80—Acids; Esters in position 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/385—Saturated compounds containing a keto group being part of a ring
- C07C49/487—Saturated compounds containing a keto group being part of a ring containing hydroxy groups
- C07C49/507—Saturated compounds containing a keto group being part of a ring containing hydroxy groups polycyclic
- C07C49/513—Saturated compounds containing a keto group being part of a ring containing hydroxy groups polycyclic a keto group being part of a condensed ring system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/70—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with ring systems containing two or more relevant rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/72—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 spiro-condensed with carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
- C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
- C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
- C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
- C07C2603/16—Benz[e]indenes; Hydrogenated benz[e]indenes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Dermatology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyridine Compounds (AREA)
- Cosmetics (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8103520 | 1981-02-23 | ||
| FR8103520A FR2500441A1 (fr) | 1981-02-23 | 1981-02-23 | Nouveaux medicaments derives de la 3-hydroxy dodecahydro benz (e) inden-7-one, produits derives de la 3-hydroxy dodecahydro benz (e) inden-7-one et leur procede de preparation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK75282A true DK75282A (da) | 1982-08-24 |
| DK167113B1 DK167113B1 (da) | 1993-08-30 |
Family
ID=9255514
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK075282A DK167113B1 (da) | 1981-02-23 | 1982-02-22 | Analogifremgangsmaade til fremstilling af 3-hydroxydodecahydrobenz(e)inden-7-on-derivater |
Country Status (11)
| Country | Link |
|---|---|
| US (5) | US4466971A (da) |
| EP (1) | EP0059146B1 (da) |
| JP (2) | JPS57156430A (da) |
| AT (1) | ATE15761T1 (da) |
| AU (1) | AU547375B2 (da) |
| CA (1) | CA1195982A (da) |
| DE (1) | DE3266460D1 (da) |
| DK (1) | DK167113B1 (da) |
| FR (1) | FR2500441A1 (da) |
| IE (1) | IE52327B1 (da) |
| ZA (1) | ZA821001B (da) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2500441A1 (fr) * | 1981-02-23 | 1982-08-27 | Roussel Uclaf | Nouveaux medicaments derives de la 3-hydroxy dodecahydro benz (e) inden-7-one, produits derives de la 3-hydroxy dodecahydro benz (e) inden-7-one et leur procede de preparation |
| TW224048B (da) * | 1992-03-30 | 1994-05-21 | Hoechst Roussel Pharma | |
| KR100826485B1 (ko) | 1999-10-14 | 2008-05-02 | 가켄 세야쿠 가부시키가이샤 | 테트라히드로퀴놀린 유도체 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1359675A (fr) * | 1963-01-14 | 1964-04-30 | Roussel Uclaf | Nouveaux composés tricycliques et procédé de préparation |
| US3499912A (en) * | 1963-11-06 | 1970-03-10 | Hoffmann La Roche | Process for the preparation of 5-oxo-11alpha-hydroxy - 3,5 - seco-a-nor-pregnan-3-oic acid - 3,11 lactones and derivatives thereof |
| US3956316A (en) * | 1964-09-29 | 1976-05-11 | Hoffmann-La Roche Inc. | 11-Substituted-desA-pregnanes and derivatives thereof |
| US3412107A (en) * | 1964-09-29 | 1968-11-19 | Hoffmann La Roche | 11-hydroxy-5-oxo-3, 5-seco-a-nor-androstan-3-oic acid 3, 11-lactones |
| CH558343A (de) * | 1965-03-25 | 1975-01-31 | Hoffmann La Roche | Verfahren zur herstellung von 9(beta),10(alpha)-steroiden. |
| US3574688A (en) * | 1966-03-22 | 1971-04-13 | Roussel Uclaf | Unsaturated 2-oxa steroid derivatives and process for their preparation |
| US3496199A (en) * | 1968-06-17 | 1970-02-17 | Hoffmann La Roche | Process for the preparation of 9beta,10alpha-steroids |
| US3984473A (en) * | 1968-10-04 | 1976-10-05 | Hoffmann-La Roche Inc. | Stereospecific total steroidal synthesis via substituted C/D-trans indanones |
| US3984474A (en) * | 1975-05-30 | 1976-10-05 | E. R. Squibb & Sons, Inc. | 4,5-Secoandrostanes |
| JPS5538316A (en) * | 1978-09-08 | 1980-03-17 | Takeda Chem Ind Ltd | Intermediate for synthesis of steroid and its preparation |
| CA1195997A (en) * | 1979-02-23 | 1985-10-29 | Andor Furst | Dea-steroids |
| FR2500441A1 (fr) * | 1981-02-23 | 1982-08-27 | Roussel Uclaf | Nouveaux medicaments derives de la 3-hydroxy dodecahydro benz (e) inden-7-one, produits derives de la 3-hydroxy dodecahydro benz (e) inden-7-one et leur procede de preparation |
-
1981
- 1981-02-23 FR FR8103520A patent/FR2500441A1/fr active Granted
-
1982
- 1982-02-16 ZA ZA821001A patent/ZA821001B/xx unknown
- 1982-02-18 DE DE8282400285T patent/DE3266460D1/de not_active Expired
- 1982-02-18 EP EP82400285A patent/EP0059146B1/fr not_active Expired
- 1982-02-18 AT AT82400285T patent/ATE15761T1/de not_active IP Right Cessation
- 1982-02-19 US US06/350,151 patent/US4466971A/en not_active Expired - Lifetime
- 1982-02-22 AU AU80699/82A patent/AU547375B2/en not_active Ceased
- 1982-02-22 CA CA000396753A patent/CA1195982A/fr not_active Expired
- 1982-02-22 DK DK075282A patent/DK167113B1/da not_active IP Right Cessation
- 1982-02-23 IE IE379/82A patent/IE52327B1/en not_active IP Right Cessation
- 1982-02-23 JP JP57026928A patent/JPS57156430A/ja active Granted
-
1983
- 1983-10-19 US US06/543,315 patent/US4607054A/en not_active Expired - Lifetime
-
1986
- 1986-04-24 US US06/855,905 patent/US4849454A/en not_active Expired - Lifetime
-
1988
- 1988-07-25 US US07/223,636 patent/US4927975A/en not_active Expired - Lifetime
-
1990
- 1990-02-09 JP JP2028621A patent/JPH02243646A/ja active Granted
- 1990-03-30 US US07/502,922 patent/US5158981A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0420893B2 (da) | 1992-04-07 |
| IE52327B1 (en) | 1987-09-16 |
| US4466971A (en) | 1984-08-21 |
| ATE15761T1 (de) | 1985-10-15 |
| JPH02243646A (ja) | 1990-09-27 |
| EP0059146B1 (fr) | 1985-09-25 |
| DK167113B1 (da) | 1993-08-30 |
| US4849454A (en) | 1989-07-18 |
| JPS57156430A (en) | 1982-09-27 |
| CA1195982A (fr) | 1985-10-29 |
| DE3266460D1 (en) | 1985-10-31 |
| FR2500441B1 (da) | 1984-10-19 |
| AU8069982A (en) | 1982-09-02 |
| ZA821001B (en) | 1983-01-26 |
| FR2500441A1 (fr) | 1982-08-27 |
| JPH0466855B2 (da) | 1992-10-26 |
| EP0059146A1 (fr) | 1982-09-01 |
| US4927975A (en) | 1990-05-22 |
| US4607054A (en) | 1986-08-19 |
| AU547375B2 (en) | 1985-10-17 |
| US5158981A (en) | 1992-10-27 |
| IE820379L (en) | 1982-08-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B1 | Patent granted (law 1993) | ||
| PUP | Patent expired |