ZA806180B - Myocardium-protecting pyridine derivatives having an anti-arrhythmic activity and an activity as blood-platelets antiaggregants - Google Patents

Myocardium-protecting pyridine derivatives having an anti-arrhythmic activity and an activity as blood-platelets antiaggregants

Info

Publication number
ZA806180B
ZA806180B ZA00806180A ZA806180A ZA806180B ZA 806180 B ZA806180 B ZA 806180B ZA 00806180 A ZA00806180 A ZA 00806180A ZA 806180 A ZA806180 A ZA 806180A ZA 806180 B ZA806180 B ZA 806180B
Authority
ZA
South Africa
Prior art keywords
activity
antiaggregants
myocardium
platelets
protecting
Prior art date
Application number
ZA00806180A
Other languages
English (en)
Inventor
J Lansen
C Bernhart
H Demarne
Original Assignee
Cm Ind
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cm Ind filed Critical Cm Ind
Publication of ZA806180B publication Critical patent/ZA806180B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/57Nitriles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/56Amides

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA00806180A 1979-10-11 1980-10-07 Myocardium-protecting pyridine derivatives having an anti-arrhythmic activity and an activity as blood-platelets antiaggregants ZA806180B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7925370A FR2467200A1 (fr) 1979-10-11 1979-10-11 Derives du pyrrole actifs sur les troubles du rythme cardiovasculaire

Publications (1)

Publication Number Publication Date
ZA806180B true ZA806180B (en) 1981-11-25

Family

ID=9230594

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00806180A ZA806180B (en) 1979-10-11 1980-10-07 Myocardium-protecting pyridine derivatives having an anti-arrhythmic activity and an activity as blood-platelets antiaggregants

Country Status (26)

Country Link
US (1) US4356177A (xx)
EP (1) EP0027412B1 (xx)
JP (1) JPS5661355A (xx)
AR (2) AR231129A1 (xx)
AT (1) ATE5561T1 (xx)
AU (1) AU540556B2 (xx)
BR (1) BR8006547A (xx)
CA (1) CA1156653A (xx)
CS (2) CS225823B2 (xx)
DD (1) DD153549A5 (xx)
DE (1) DE3065906D1 (xx)
DK (1) DK156650C (xx)
ES (1) ES495745A0 (xx)
FI (1) FI75339C (xx)
FR (1) FR2467200A1 (xx)
GR (1) GR69616B (xx)
HU (1) HU184330B (xx)
IE (1) IE50827B1 (xx)
IL (1) IL61250A (xx)
NO (1) NO153849C (xx)
NZ (1) NZ195233A (xx)
PH (1) PH18748A (xx)
PT (1) PT71888B (xx)
SU (2) SU1011048A3 (xx)
YU (2) YU42537B (xx)
ZA (1) ZA806180B (xx)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2535721A1 (fr) * 1982-11-08 1984-05-11 Sanofi Sa Derives de la piperidinedione protecteurs du myocarde presentant une acticite antiarythmique, leur procede de preparation et les medicaments qui contiennent lesdits derives
FR2535722B1 (fr) * 1982-11-08 1985-06-28 Sanofi Sa Derives de la g-butyrolactone protecteurs du myocarde presentant une activite antiarythmique, procede pour leur preparation et medicaments en contenant
US4847301A (en) * 1985-11-13 1989-07-11 Pennwalt Corporation Methods of use of α-(aminoalkyl)-arylacetic acid derivatives
US4783537A (en) * 1985-11-13 1988-11-08 Pennwalt Corporation α-(aminoalkyl)-arylacetic acid derivatives
FR2856061A1 (fr) * 2003-06-11 2004-12-17 Chrysalon Derives polycycliques ortho-condenses de l'aminopyrrole a substituant electroattracteur chimiotheques combinatoires desdits derives et leur procede d'obtention

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL70757C (xx) * 1947-10-13
GB915804A (en) * 1958-04-12 1963-01-16 Degussa Process for the production of basically substituted carboxylic acid amides
FR2485M (fr) * 1961-05-17 1964-04-27 Searle & Co Nouveaux régulateurs cardiaques.
CA1073892A (en) * 1976-08-03 1980-03-18 John M. Holmes Mixed metal amide catalysts for h-d exchange in amines

Also Published As

Publication number Publication date
ES8200347A1 (es) 1981-11-16
FR2467200A1 (fr) 1981-04-17
PH18748A (en) 1985-09-19
IE802112L (en) 1981-04-11
IL61250A0 (en) 1980-12-31
DD153549A5 (de) 1982-01-13
DK156650B (da) 1989-09-18
NO803051L (no) 1981-04-13
SU1011048A3 (ru) 1983-04-07
ES495745A0 (es) 1981-11-16
FI75339B (fi) 1988-02-29
DK428280A (da) 1981-04-12
CS225840B2 (en) 1984-02-13
FR2467200B1 (xx) 1982-07-02
EP0027412B1 (fr) 1983-12-14
AR231129A1 (es) 1984-09-28
ATE5561T1 (de) 1983-12-15
GR69616B (xx) 1982-07-05
HU184330B (en) 1984-08-28
NZ195233A (en) 1983-05-10
SU1127529A3 (ru) 1984-11-30
JPS5661355A (en) 1981-05-26
JPH0115501B2 (xx) 1989-03-17
YU21283A (en) 1983-09-30
FI75339C (fi) 1988-06-09
PT71888B (fr) 1981-08-14
AR231975A1 (es) 1985-04-30
CA1156653A (en) 1983-11-08
PT71888A (fr) 1980-11-01
IE50827B1 (en) 1986-07-23
BR8006547A (pt) 1981-04-14
AU540556B2 (en) 1984-11-22
IL61250A (en) 1983-11-30
DE3065906D1 (en) 1984-01-19
YU42537B (en) 1988-10-31
AU6328380A (en) 1981-04-30
NO153849B (no) 1986-02-24
NO153849C (no) 1986-06-04
YU261180A (en) 1983-09-30
FI803221L (fi) 1981-04-12
US4356177A (en) 1982-10-26
CS225823B2 (en) 1984-02-13
DK156650C (da) 1990-02-12
EP0027412A1 (fr) 1981-04-22

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