ZA775905B - Improvements relating to 1-aryloxy-2-hydroxy-3-alkyleneaminopropanes - Google Patents

Improvements relating to 1-aryloxy-2-hydroxy-3-alkyleneaminopropanes

Info

Publication number
ZA775905B
ZA775905B ZA00775905A ZA775905A ZA775905B ZA 775905 B ZA775905 B ZA 775905B ZA 00775905 A ZA00775905 A ZA 00775905A ZA 775905 A ZA775905 A ZA 775905A ZA 775905 B ZA775905 B ZA 775905B
Authority
ZA
South Africa
Prior art keywords
alkyleneaminopropanes
aryloxy
hydroxy
improvements relating
relating
Prior art date
Application number
ZA00775905A
Other languages
English (en)
Inventor
A Mentrup
W Hoefke
H Koeppe
E Renth
K Schromm
G Muacevic
Original Assignee
Boehringer Sohn Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim
Publication of ZA775905B publication Critical patent/ZA775905B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • C07D209/34—Oxygen atoms in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/30—Oxygen or sulfur atoms
    • C07D233/32—One oxygen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/26—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
    • C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
    • C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D265/18—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
ZA00775905A 1976-10-05 1977-10-04 Improvements relating to 1-aryloxy-2-hydroxy-3-alkyleneaminopropanes ZA775905B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19762644833 DE2644833A1 (de) 1976-10-05 1976-10-05 Neue 1-aryloxy-2-hydroxy-3-alkylenaminopropane und verfahren zu ihrer herstellung

Publications (1)

Publication Number Publication Date
ZA775905B true ZA775905B (en) 1979-06-27

Family

ID=5989679

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00775905A ZA775905B (en) 1976-10-05 1977-10-04 Improvements relating to 1-aryloxy-2-hydroxy-3-alkyleneaminopropanes

Country Status (33)

Country Link
US (7) US4256756A (da)
JP (1) JPS5368775A (da)
AT (15) AT361908B (da)
AU (1) AU514600B2 (da)
BE (1) BE859415A (da)
BG (1) BG33153A3 (da)
CA (4) CA1101859A (da)
CS (1) CS197304B2 (da)
DD (5) DD148050A5 (da)
DE (1) DE2644833A1 (da)
DK (1) DK439077A (da)
ES (16) ES462868A1 (da)
FI (1) FI69066C (da)
FR (1) FR2394534A1 (da)
GB (3) GB1592976A (da)
GR (1) GR64229B (da)
HK (1) HK19385A (da)
HU (1) HU177173B (da)
IE (3) IE46159B1 (da)
IL (1) IL53043A (da)
LU (1) LU78240A1 (da)
MY (1) MY8500909A (da)
NL (1) NL7710840A (da)
NO (1) NO151411C (da)
NZ (1) NZ185356A (da)
PH (4) PH15763A (da)
PL (1) PL113879B1 (da)
PT (1) PT67107B (da)
SE (1) SE442400B (da)
SG (1) SG70884G (da)
SU (1) SU665801A3 (da)
YU (1) YU40484B (da)
ZA (1) ZA775905B (da)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4404380A (en) * 1977-02-14 1983-09-13 Mead Johnson & Company Triazolopyrimidines
DE2833140A1 (de) * 1978-07-28 1980-02-07 Boehringer Sohn Ingelheim Neue n-substituierte heterocyclen
SE8003278L (sv) * 1979-05-04 1980-11-05 Continental Pharma Fenyletylaminderivat
US4349673A (en) * 1980-12-23 1982-09-14 Merck & Co., Inc. Benzoxazines
US4656168A (en) * 1980-12-23 1987-04-07 Merck & Co., Inc. (3-aralkylamino-2-or-propoxy)heterocyclic compounds in method of effecting bronchodilation
US4473501A (en) * 1981-05-04 1984-09-25 G. D. Searle & Co. Dihydro azino isoquinolines
US4379508A (en) * 1981-10-14 1983-04-12 Nestier Corporation Nesting tray with stacking keyed interlock
IT1193608B (it) * 1983-01-21 1988-07-21 Pierrel Spa Derivati di arilossipropanolamina,procedimento per la loro preparazione composizioni farmaceutiche che li contengono e loro impiego terapeutico
DE3324903A1 (de) * 1983-07-09 1985-01-17 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung substituierter ethylenharnstoffe sowie neue n-vinylethylenharnstoffe
GB8419797D0 (en) * 1984-08-03 1984-09-05 Beecham Group Plc Compounds
DE3807922A1 (de) * 1988-03-10 1989-09-21 Boehringer Mannheim Gmbh Substituierte heterocyclen, verfahren zu ihrer herstellung sowie arzneimittel, die diese verbindungen enthalten
TW203049B (da) * 1990-04-13 1993-04-01 Yamanouchi Pharma Co Ltd
US6860524B1 (en) 1993-05-14 2005-03-01 William W. Rowley Polyolefin connectors
US6557907B2 (en) 1993-05-14 2003-05-06 William W. Rowley Polyethylene connectors
CA2330611A1 (en) 1998-05-22 1999-12-02 The Board Of Trustees Of The Leland Stanford Junior University Bifunctional molecules and therapies based thereon
DE60234057D1 (de) 2001-07-25 2009-11-26 Raptor Pharmaceutical Inc Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke
US6848719B2 (en) 2001-09-06 2005-02-01 William W. Rowley Bendable polymer-lined water heater connector
TWI316511B (en) * 2002-11-26 2009-11-01 Smithkline Beecham Corp Calcilytic compounds
JP2006513222A (ja) * 2002-12-23 2006-04-20 アルテシアン セラピューティック，インコーポレイティド アドレナリン性β受容体およびホスホジエステラーゼに対する抑制活性を有する強心性化合物
DE102004045648A1 (de) * 2004-09-21 2006-03-23 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Betamimetika zur Behandlung von Atemwegserkrankungen
JP2008521805A (ja) * 2004-11-30 2008-06-26 アーテシアン セラピューティクス， インコーポレイテッド β−アドレナリン作用性受容体およびホスホジエステラーゼに対する阻害活性を有する強心性化合物
SI1889198T1 (sl) 2005-04-28 2015-02-27 Proteus Digital Health, Inc. Farma-informacijski sistem
MX2009002893A (es) 2006-09-18 2009-07-10 Raptor Pharmaceutical Inc Tratamiento de trastornos hepaticos mediante la administracion de conjugados de la proteina asociada al receptor (rap).
US8993641B2 (en) * 2007-11-29 2015-03-31 Innolex Investment Corporation Preservation of cosmetics, toiletry and pharmaceutical compositions
WO2010095940A2 (en) 2009-02-20 2010-08-26 To-Bbb Holding B.V. Glutathione-based drug delivery system
NZ596876A (en) 2009-05-06 2014-01-31 Lab Skin Care Inc Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL284529A (da) * 1961-10-24
GB1066613A (en) * 1965-03-03 1967-04-26 Ici Ltd Naphthalene derivatives
GB1349357A (en) * 1969-11-28 1974-04-03 Teikoku Hormone Mfg Co Ltd Propylamines
ZA71932B (en) * 1970-02-27 1971-10-27 Ici Ltd Organic compounds
BE787103A (fr) * 1971-08-04 1973-02-02 Pfizer Nouveaux derives de propanolamine et composition pharmaceutiqueles contenant
US3818017A (en) * 1973-01-04 1974-06-18 Janssen Pharmaceutica Nv 1-{8 1-(2-hydroxy-3-aryloxypropyl)-4-piperidyl{9 -2-benzimidazolinones and related compounds
US3894030A (en) * 1973-01-04 1975-07-08 Janssen Pharmaceutica Nv 1-{8 1-(2-Hydroxy-3-aryloxypropyl)-4-piperidyl{9 -2-benzimidazolinones and related compounds
GB1456525A (en) * 1973-07-18 1976-11-24 Ici Ltd Process for the manufacture of alkanolamine derivatives
DE2503222A1 (de) * 1975-01-27 1976-07-29 Boehringer Sohn Ingelheim Verfahren zur herstellung von 1-aryl- oxy-3-n-substituierten aminopropanderivaten
US4081447A (en) * 1975-04-09 1978-03-28 Abbott Laboratories 5-[2-Hydroxy-3-(3,4-dimethoxy phenethylamino)]-propoxy-3,4-dihydro carbostyril and pharmaceutically acceptable salts thereof
CH624395A5 (da) * 1976-01-08 1981-07-31 Ciba Geigy Ag
DE2609645A1 (de) * 1976-03-09 1977-09-15 Boehringer Sohn Ingelheim Aminoalkylheterocyclen

Also Published As

Publication number Publication date
ES471796A1 (es) 1979-02-01
NL7710840A (nl) 1978-04-07
ATA57380A (de) 1980-10-15
ATA57180A (de) 1980-09-15
US4381309A (en) 1983-04-26
ATA57880A (de) 1980-10-15
PL201286A1 (pl) 1978-12-04
DD143074A5 (de) 1980-07-30
IE46158L (en) 1978-04-05
ES471803A1 (es) 1979-02-01
HU177173B (en) 1981-08-28
FR2394534A1 (fr) 1979-01-12
AT362362B (de) 1981-05-11
AT362363B (de) 1981-05-11
LU78240A1 (da) 1979-02-02
ES471798A1 (es) 1979-02-01
AU514600B2 (en) 1981-02-19
ES471808A1 (es) 1979-02-01
DD148050A5 (de) 1981-05-06
AT361913B (de) 1981-04-10
ATA56980A (de) 1980-09-15
PH19028A (en) 1985-12-06
DD148051A5 (de) 1981-05-06
ATA679377A (de) 1980-09-15
PH16053A (en) 1983-06-09
GB1592975A (en) 1981-07-15
CS197304B2 (en) 1980-04-30
IE822409L (en) 1978-04-05
US4256756A (en) 1981-03-17
US4604468A (en) 1986-08-05
FR2394534B1 (da) 1982-04-30
IE822410L (en) 1978-04-05
ATA57480A (de) 1980-10-15
DK439077A (da) 1978-04-06
AT363080B (de) 1981-07-10
AT361912B (de) 1981-04-10
ES471802A1 (es) 1979-02-01
YU40484B (en) 1986-02-28
US4212877A (en) 1980-07-15
ATA58080A (de) 1981-04-15
DD134642A5 (de) 1979-03-14
AT362364B (de) 1981-05-11
ES471800A1 (es) 1979-02-01
IE46159B1 (en) 1983-03-09
BE859415A (fr) 1978-04-05
SE442400B (sv) 1985-12-23
YU236977A (en) 1983-01-21
ES462868A1 (es) 1978-12-16
AT361908B (de) 1981-04-10
ES471805A1 (es) 1979-02-01
ES471797A1 (es) 1979-02-01
AT363081B (de) 1981-07-10
ATA56880A (de) 1980-09-15
DD148052A5 (de) 1981-05-06
ATA57680A (de) 1980-12-15
ES471804A1 (es) 1979-02-01
IL53043A (en) 1982-01-31
GR64229B (en) 1980-02-14
NO151411B (no) 1984-12-27
IL53043A0 (en) 1977-12-30
DE2644833A1 (de) 1978-04-20
NO773384L (no) 1978-04-06
ATA57980A (de) 1980-12-15
AT363079B (de) 1981-07-10
CA1126271A (en) 1982-06-22
ATA57580A (de) 1980-12-15
BG33153A3 (en) 1982-12-15
IE46160B1 (en) 1983-03-09
CA1127643A (en) 1982-07-13
ATA57080A (de) 1980-09-15
AT363082B (de) 1981-07-10
AT361914B (de) 1981-04-10
ES471801A1 (es) 1979-02-01
MY8500909A (en) 1985-12-31
PH15763A (en) 1983-03-22
CA1125751A (en) 1982-06-15
ATA57780A (de) 1980-12-15
US4255430A (en) 1981-03-10
AU2933377A (en) 1979-04-12
ES471806A1 (es) 1979-02-01
PH18363A (en) 1985-06-13
US4296117A (en) 1981-10-20
SE7711168L (sv) 1978-05-18
GB1592976A (en) 1981-07-15
PT67107B (de) 1980-04-07
ATA56780A (de) 1980-09-15
AT361915B (de) 1981-04-10
FI772823A (fi) 1978-04-06
FI69066C (fi) 1985-12-10
ES471794A1 (es) 1979-02-01
AT362365B (de) 1981-05-11
NO151411C (no) 1985-04-10
ES471807A1 (es) 1979-02-01
JPS5368775A (en) 1978-06-19
ES471795A1 (es) 1979-02-01
SU665801A3 (ru) 1979-05-30
GB1592977A (en) 1981-07-15
AT364828B (de) 1981-11-25
NZ185356A (en) 1981-05-01
CA1101859A (en) 1981-05-26
FI69066B (fi) 1985-08-30
PL113879B1 (en) 1981-01-31
PT67107A (de) 1977-11-01
HK19385A (en) 1985-03-22
JPS6210988B2 (da) 1987-03-10
ES471799A1 (es) 1979-02-01
ATA57280A (de) 1980-10-15
AT361911B (de) 1981-04-10
US4343800A (en) 1982-08-10
SG70884G (en) 1985-04-04
IE46158B1 (en) 1983-03-09

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