ZA766381B - New piperidine derivatives - Google Patents
New piperidine derivativesInfo
- Publication number
- ZA766381B ZA766381B ZA766381A ZA766381A ZA766381B ZA 766381 B ZA766381 B ZA 766381B ZA 766381 A ZA766381 A ZA 766381A ZA 766381 A ZA766381 A ZA 766381A ZA 766381 B ZA766381 B ZA 766381B
- Authority
- ZA
- South Africa
- Prior art keywords
- piperidine derivatives
- new piperidine
- new
- derivatives
- piperidine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19752549999 DE2549999A1 (de) | 1975-11-07 | 1975-11-07 | Piperidin-derivate und verfahren zu ihrer herstellung |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA766381B true ZA766381B (en) | 1977-10-26 |
Family
ID=5961166
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA766381A ZA766381B (en) | 1975-11-07 | 1976-10-25 | New piperidine derivatives |
Country Status (20)
Country | Link |
---|---|
US (1) | US4243807A (ru) |
JP (1) | JPS6055509B2 (ru) |
AT (1) | AT352726B (ru) |
BE (1) | BE847973A (ru) |
CA (1) | CA1077942A (ru) |
CH (3) | CH624102A5 (ru) |
DD (1) | DD126942A5 (ru) |
DE (1) | DE2549999A1 (ru) |
DK (1) | DK494876A (ru) |
FI (1) | FI763148A (ru) |
FR (1) | FR2330678A1 (ru) |
GB (1) | GB1502050A (ru) |
HU (1) | HU171237B (ru) |
IE (1) | IE43866B1 (ru) |
IT (1) | IT1063618B (ru) |
LU (1) | LU76141A1 (ru) |
NL (1) | NL7612286A (ru) |
SE (1) | SE7612234L (ru) |
SU (3) | SU633473A3 (ru) |
ZA (1) | ZA766381B (ru) |
Families Citing this family (38)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ZA848275B (en) * | 1983-12-28 | 1985-08-28 | Degussa | New piridine-2-ethers or pyridine-2-thioethers having a nitrogen-containing cycloaliphatic ring |
US4556664A (en) * | 1984-03-13 | 1985-12-03 | Gunnar A. K. Aberg | Method and composition for the treatment of cardiac arrhythmias |
IE66332B1 (en) * | 1986-11-03 | 1995-12-27 | Novo Nordisk As | Piperidine compounds and their preparation and use |
US5231184A (en) * | 1987-11-23 | 1993-07-27 | Janssen Pharmaceutica N.V. | Pridazinamine derivatives |
US4822778A (en) * | 1988-01-19 | 1989-04-18 | Gunnar Aberg | Membrane stabilizing phenoxy-piperidine compounds and pharmaceutical compositions employing such compounds |
US5109002A (en) * | 1989-09-08 | 1992-04-28 | Du Pont Merck Pharmaceutical Company | Antipsychotic 1-cycloalkylpiperidines |
US5264420A (en) * | 1990-09-27 | 1993-11-23 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
IL99537A (en) * | 1990-09-27 | 1995-11-27 | Merck & Co Inc | Fibrinogen receptor antagonists and pharmaceutical preparations containing them |
NZ239846A (en) * | 1990-09-27 | 1994-11-25 | Merck & Co Inc | Sulphonamide derivatives and pharmaceutical compositions thereof |
FR2667317B1 (fr) * | 1990-10-02 | 1992-12-04 | Synthelabo | Derives de 2-aminopyrimidine-4-carboxamide, leur preparation et leur application en therapeutique. |
US5321034A (en) * | 1991-05-07 | 1994-06-14 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
WO1992019595A1 (en) * | 1991-05-07 | 1992-11-12 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
US5272158A (en) * | 1991-10-29 | 1993-12-21 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
US5416099A (en) * | 1991-10-29 | 1995-05-16 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
US5389631A (en) * | 1991-10-29 | 1995-02-14 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
US5358956A (en) * | 1992-10-14 | 1994-10-25 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
ATE188379T1 (de) * | 1992-10-14 | 2000-01-15 | Merck & Co Inc | Fibrinogenrezeptor-antagonisten |
AU675689B2 (en) * | 1992-12-01 | 1997-02-13 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
US5441952A (en) * | 1993-04-05 | 1995-08-15 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
US5334596A (en) * | 1993-05-11 | 1994-08-02 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
US5397791A (en) * | 1993-08-09 | 1995-03-14 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
US5821241A (en) * | 1994-02-22 | 1998-10-13 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
US5719144A (en) * | 1995-02-22 | 1998-02-17 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
US5750147A (en) | 1995-06-07 | 1998-05-12 | Emisphere Technologies, Inc. | Method of solubilizing and encapsulating itraconazole |
DE69615063T2 (de) * | 1995-09-28 | 2002-04-25 | Kaken Pharmaceutical Co., Ltd. | Verfahren zur herstellung von 4-methylen piperidinen |
US5789421A (en) * | 1995-10-26 | 1998-08-04 | Merck & Co., Inc. | Fibrinogen receptor antagonist |
US5780480A (en) * | 1996-02-28 | 1998-07-14 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
US5889023A (en) * | 1996-05-10 | 1999-03-30 | Merck & Co., Inc. | Fibrinogen receptor antagonist |
US5981584A (en) * | 1997-02-06 | 1999-11-09 | Merck & Co., Inc. | Fibrinogen receptor antagonist prodrugs |
TWI438190B (zh) * | 2008-07-24 | 2014-05-21 | Theravance Inc | 3-(苯氧基苯基甲基)吡咯啶化合物 |
BRPI0921595B8 (pt) | 2008-11-14 | 2021-05-25 | Theravance Biopharma R&D Ip Llc | sal monocloridrato cristalino de 4-[2,4,6-(trifluorfenoximetil)fenil]piperidina, seu processo de preparo e usos |
JP2012524098A (ja) * | 2009-04-15 | 2012-10-11 | セラヴァンス, インコーポレーテッド | 3−(フェノキシピロリジン−3−イル−メチル)ヘテロアリール、3−(フェニルピロリジン−3−イルメトキシ)ヘテロアリールおよび3−(ヘテロアリールピロリジン−3−イルメトキシ)ヘテロアリール化合物 |
CN102471258A (zh) * | 2009-07-13 | 2012-05-23 | 施万制药 | 3-苯氧基甲基吡咯烷化合物 |
WO2011011231A1 (en) | 2009-07-21 | 2011-01-27 | Theravance, Inc. | 3-phenoxymethylpyrrolidine compounds |
JP5705239B2 (ja) | 2010-01-11 | 2015-04-22 | セラヴァンス バイオファーマ アール&ディー アイピー, エルエルシー | セロトニンおよびノルエピネフリン再取込みインヒビターとしての1−(2−フェノキシメチルフェニル)ピペラジン化合物 |
JP5769348B2 (ja) * | 2010-03-22 | 2015-08-26 | セラヴァンス バイオファーマ アール&ディー アイピー, エルエルシー | 1−(2−フェノキシメチルヘテロアリール)ピペリジン化合物および1−(2−フェノキシメチルヘテロアリール)ピペラジン化合物 |
CA2811641A1 (en) | 2010-10-11 | 2012-04-19 | Theravance, Inc. | Serotonin reuptake inhibitors |
WO2012075239A1 (en) | 2010-12-03 | 2012-06-07 | Theravance, Inc. | Serotonin reuptake inhibitors |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1268951A (en) * | 1969-06-12 | 1972-03-29 | Pfizer Ltd | Phenoxy-amines |
DE2245061A1 (de) * | 1972-09-14 | 1974-03-28 | Boehringer Mannheim Gmbh | Derivate des adenins |
DE2401254A1 (de) * | 1974-01-11 | 1975-11-27 | Boehringer Mannheim Gmbh | Neue derivate von n hoch 6-substituierten adeninen |
DE2550000A1 (de) * | 1975-11-07 | 1977-05-12 | Boehringer Mannheim Gmbh | Neue purin-derivate und verfahren zu ihrer herstellung |
-
1975
- 1975-11-07 DE DE19752549999 patent/DE2549999A1/de active Granted
-
1976
- 1976-10-25 ZA ZA766381A patent/ZA766381B/xx unknown
- 1976-10-28 CA CA264,608A patent/CA1077942A/en not_active Expired
- 1976-10-29 IE IE2394/76A patent/IE43866B1/en unknown
- 1976-11-01 US US05/737,518 patent/US4243807A/en not_active Expired - Lifetime
- 1976-11-01 HU HU76BO00001639A patent/HU171237B/hu not_active IP Right Cessation
- 1976-11-02 SU SU762415648A patent/SU633473A3/ru active
- 1976-11-02 DK DK494876A patent/DK494876A/da not_active Application Discontinuation
- 1976-11-03 FI FI763148A patent/FI763148A/fi not_active Application Discontinuation
- 1976-11-03 SE SE7612234A patent/SE7612234L/xx not_active Application Discontinuation
- 1976-11-03 CH CH1385576A patent/CH624102A5/de not_active IP Right Cessation
- 1976-11-04 BE BE172068A patent/BE847973A/xx not_active IP Right Cessation
- 1976-11-04 GB GB45916/76A patent/GB1502050A/en not_active Expired
- 1976-11-04 DD DD195610A patent/DD126942A5/xx unknown
- 1976-11-05 AT AT823776A patent/AT352726B/de not_active IP Right Cessation
- 1976-11-05 IT IT29083/76A patent/IT1063618B/it active
- 1976-11-05 FR FR7633389A patent/FR2330678A1/fr active Granted
- 1976-11-05 LU LU76141A patent/LU76141A1/xx unknown
- 1976-11-05 JP JP51133139A patent/JPS6055509B2/ja not_active Expired
- 1976-11-05 NL NL7612286A patent/NL7612286A/xx not_active Application Discontinuation
-
1977
- 1977-10-21 SU SU772534003A patent/SU662009A3/ru active
- 1977-10-21 SU SU772534004A patent/SU867298A3/ru active
-
1980
- 1980-10-03 CH CH742380A patent/CH625788A5/de not_active IP Right Cessation
- 1980-10-03 CH CH742480A patent/CH627166A5/de not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
AT352726B (de) | 1979-10-10 |
HU171237B (hu) | 1977-12-28 |
DE2549999A1 (de) | 1977-05-12 |
FR2330678A1 (fr) | 1977-06-03 |
SE7612234L (sv) | 1977-05-07 |
FR2330678B1 (ru) | 1980-11-07 |
JPS6055509B2 (ja) | 1985-12-05 |
SU662009A3 (ru) | 1979-05-05 |
ATA823776A (de) | 1979-03-15 |
SU867298A3 (ru) | 1981-09-23 |
LU76141A1 (ru) | 1977-05-18 |
CH624102A5 (ru) | 1981-07-15 |
NL7612286A (nl) | 1977-05-10 |
FI763148A (ru) | 1977-05-08 |
IE43866L (en) | 1977-05-07 |
CH625788A5 (ru) | 1981-10-15 |
IE43866B1 (en) | 1981-06-17 |
GB1502050A (en) | 1978-02-22 |
SU633473A3 (ru) | 1978-11-15 |
DK494876A (da) | 1977-05-08 |
CA1077942A (en) | 1980-05-20 |
DD126942A5 (ru) | 1977-08-24 |
JPS5259163A (en) | 1977-05-16 |
DE2549999C2 (ru) | 1989-01-26 |
US4243807A (en) | 1981-01-06 |
CH627166A5 (ru) | 1981-12-31 |
IT1063618B (it) | 1985-02-11 |
BE847973A (fr) | 1977-05-04 |
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