ZA718712B - Basically substituted benzyl phthalazone derivatives,acid salts thereof and process for the production thereof - Google Patents

Basically substituted benzyl phthalazone derivatives,acid salts thereof and process for the production thereof

Info

Publication number
ZA718712B
ZA718712B ZA718712A ZA718712A ZA718712B ZA 718712 B ZA718712 B ZA 718712B ZA 718712 A ZA718712 A ZA 718712A ZA 718712 A ZA718712 A ZA 718712A ZA 718712 B ZA718712 B ZA 718712B
Authority
ZA
South Africa
Prior art keywords
production
acid salts
substituted benzyl
basically substituted
phthalazone derivatives
Prior art date
Application number
ZA718712A
Other languages
English (en)
Inventor
D Vogelsang
G Scheffler
N Brock
D Lenke
Original Assignee
Asta Werke Ag Chem Fab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asta Werke Ag Chem Fab filed Critical Asta Werke Ag Chem Fab
Publication of ZA718712B publication Critical patent/ZA718712B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA718712A 1971-01-22 1971-12-30 Basically substituted benzyl phthalazone derivatives,acid salts thereof and process for the production thereof ZA718712B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH101271A CH572914A5 (hu) 1971-01-22 1971-01-22

Publications (1)

Publication Number Publication Date
ZA718712B true ZA718712B (en) 1972-09-27

Family

ID=4200381

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA718712A ZA718712B (en) 1971-01-22 1971-12-30 Basically substituted benzyl phthalazone derivatives,acid salts thereof and process for the production thereof

Country Status (21)

Country Link
AR (1) AR197293A1 (hu)
AT (1) AT313288B (hu)
AU (1) AU3767472A (hu)
BE (1) BE778269A (hu)
CA (1) CA1010041A (hu)
CH (1) CH572914A5 (hu)
DE (1) DE2164058C3 (hu)
DK (1) DK136981B (hu)
ES (1) ES398949A1 (hu)
FI (1) FI53704C (hu)
FR (1) FR2122517B1 (hu)
GB (1) GB1377231A (hu)
HK (1) HK62577A (hu)
HU (1) HU163979B (hu)
IL (1) IL38496A (hu)
NL (1) NL177116C (hu)
OA (1) OA04087A (hu)
PL (1) PL88930B1 (hu)
SE (1) SE404604B (hu)
YU (1) YU35361B (hu)
ZA (1) ZA718712B (hu)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE49205T1 (de) * 1984-09-14 1990-01-15 Asta Pharma Ag Substituierte benzylphthalazinon-derivate.
PT88984B (pt) * 1987-11-13 1993-01-29 Asta Medica Ag Processo para a preparação de embonato de azelastina e de composições earmacâutxcas que 0 contêm como ingrediente activo
ATE106883T1 (de) * 1987-11-13 1994-06-15 Asta Medica Ag Azelastin-embonat, verfahren zu seiner herstellung und pharmazeutische zubereitungen, die als wirkstoff azelastin-embonat enthalten.
DE3836579A1 (de) * 1987-11-13 1989-05-24 Asta Pharma Ag Azelastin enthaltende arzneimittel zur anwendung in der nase und/oder am auge
ATE84968T1 (de) * 1987-11-13 1993-02-15 Asta Medica Ag Azelastin enthaltende arzneimittel zur anwendung in der nase und/oder am auge.
DE3912292A1 (de) * 1988-04-20 1989-11-09 Asta Pharma Ag Azelastin enthaltende arzneimittel mit kontrollierter wirkstoffabgabe
US5110814A (en) * 1989-01-11 1992-05-05 Asta Pharma Ag Azelastine and its salts used to combat psoriasis
DK0396069T3 (da) * 1989-05-05 1994-07-25 Asta Medica Ag Salte af azelastin med forbedret opløselighed
DE4207234A1 (de) * 1992-03-07 1993-09-09 Asta Medica Ag Neue aminocarbonsaeure-derivate mit antiallergischer/antiasthmatischer wirkung und verfahren zu deren herstellung
DE4345224C2 (de) * 1993-12-18 1999-07-01 Asta Medica Ag Verfahren zur Herstellung von Säureadditionssalzen des Azelastins und Flezelastins
DE4343409C2 (de) * 1993-12-18 1997-03-20 Asta Medica Ag Verbessertes Verfahren zur Herstellung von Hexahydroazepinonen und Hexahydroazepinolen
GB2389530B (en) 2002-06-14 2007-01-10 Cipla Ltd Pharmaceutical compositions
NZ555501A (en) 2004-11-24 2010-01-29 Medpointe Healthcare Inc Compositions comprising azelastine and methods of use thereof
US8758816B2 (en) 2004-11-24 2014-06-24 Meda Pharmaceuticals Inc. Compositions comprising azelastine and methods of use thereof
US20070020330A1 (en) 2004-11-24 2007-01-25 Medpointe Healthcare Inc. Compositions comprising azelastine and methods of use thereof
US20090105225A1 (en) * 2006-04-20 2009-04-23 Glaxo Group Limited 2-Substituted 4-Benzylphthalazinone Derivatives as Histamine H1 and H3 Antagonists

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1046625B (de) * 1957-08-15 1958-12-18 Hydrierwerk Rodleben Veb Verfahren zur Herstellung basisch substituierter Phthalazone
GB1100911A (en) * 1963-08-20 1968-01-24 Benger Lab Ltd Phthalazine derivatives
FR1512879A (fr) * 1966-10-28 1968-02-09 Hydrierwerk Rodleben Veb Procédé pour la fabrication de phtalazones avec substituants basiques

Also Published As

Publication number Publication date
BE778269A (fr) 1972-07-19
AR197293A1 (es) 1974-03-29
NL177116C (nl) 1985-08-01
YU11272A (en) 1980-06-30
IL38496A (en) 1975-05-22
YU35361B (en) 1980-12-31
PL88930B1 (hu) 1976-10-30
DE2164058A1 (de) 1972-07-27
DK136981B (da) 1977-12-27
SE404604B (sv) 1978-10-16
FI53704C (fi) 1978-07-10
CH572914A5 (hu) 1976-02-27
AT313288B (de) 1974-02-11
FI53704B (hu) 1978-03-31
AU3767472A (en) 1973-07-12
GB1377231A (en) 1974-12-11
DE2164058C3 (de) 1981-08-13
ES398949A1 (es) 1975-06-01
DE2164058B2 (de) 1980-10-23
DK136981C (hu) 1978-06-05
HU163979B (hu) 1973-12-28
NL177116B (nl) 1985-03-01
CA1010041A (en) 1977-05-10
OA04087A (fr) 1979-10-30
NL7200400A (hu) 1972-07-25
SU440838A3 (hu) 1974-08-25
IL38496A0 (en) 1972-03-28
FR2122517B1 (hu) 1975-08-01
HK62577A (en) 1977-12-30
FR2122517A1 (hu) 1972-09-01

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