IL38496A - Basically substituted 4-benzyl phthalazone derivatives,acid salts thereof and process for the production thereof - Google Patents

Basically substituted 4-benzyl phthalazone derivatives,acid salts thereof and process for the production thereof

Info

Publication number
IL38496A
IL38496A IL38496A IL3849672A IL38496A IL 38496 A IL38496 A IL 38496A IL 38496 A IL38496 A IL 38496A IL 3849672 A IL3849672 A IL 3849672A IL 38496 A IL38496 A IL 38496A
Authority
IL
Israel
Prior art keywords
benzyl
production
acid salts
basically substituted
phthalazone derivatives
Prior art date
Application number
IL38496A
Other languages
English (en)
Other versions
IL38496A0 (en
Original Assignee
Asta Werke Ag Chem Fab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asta Werke Ag Chem Fab filed Critical Asta Werke Ag Chem Fab
Publication of IL38496A0 publication Critical patent/IL38496A0/xx
Publication of IL38496A publication Critical patent/IL38496A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL38496A 1971-01-22 1972-01-03 Basically substituted 4-benzyl phthalazone derivatives,acid salts thereof and process for the production thereof IL38496A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH101271A CH572914A5 (xx) 1971-01-22 1971-01-22

Publications (2)

Publication Number Publication Date
IL38496A0 IL38496A0 (en) 1972-03-28
IL38496A true IL38496A (en) 1975-05-22

Family

ID=4200381

Family Applications (1)

Application Number Title Priority Date Filing Date
IL38496A IL38496A (en) 1971-01-22 1972-01-03 Basically substituted 4-benzyl phthalazone derivatives,acid salts thereof and process for the production thereof

Country Status (21)

Country Link
AR (1) AR197293A1 (xx)
AT (1) AT313288B (xx)
AU (1) AU3767472A (xx)
BE (1) BE778269A (xx)
CA (1) CA1010041A (xx)
CH (1) CH572914A5 (xx)
DE (1) DE2164058C3 (xx)
DK (1) DK136981B (xx)
ES (1) ES398949A1 (xx)
FI (1) FI53704C (xx)
FR (1) FR2122517B1 (xx)
GB (1) GB1377231A (xx)
HK (1) HK62577A (xx)
HU (1) HU163979B (xx)
IL (1) IL38496A (xx)
NL (1) NL177116C (xx)
OA (1) OA04087A (xx)
PL (1) PL88930B1 (xx)
SE (1) SE404604B (xx)
YU (1) YU35361B (xx)
ZA (1) ZA718712B (xx)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE49205T1 (de) * 1984-09-14 1990-01-15 Asta Pharma Ag Substituierte benzylphthalazinon-derivate.
PT88984B (pt) * 1987-11-13 1993-01-29 Asta Medica Ag Processo para a preparação de embonato de azelastina e de composições earmacâutxcas que 0 contêm como ingrediente activo
ATE84968T1 (de) * 1987-11-13 1993-02-15 Asta Medica Ag Azelastin enthaltende arzneimittel zur anwendung in der nase und/oder am auge.
DE3836579A1 (de) * 1987-11-13 1989-05-24 Asta Pharma Ag Azelastin enthaltende arzneimittel zur anwendung in der nase und/oder am auge
EP0316639B1 (de) * 1987-11-13 1994-06-08 ASTA Medica Aktiengesellschaft Azelastin-Embonat, Verfahren zu seiner Herstellung und pharmazeutische Zubereitungen, die als Wirkstoff Azelastin-Embonat enthalten
DE3912292A1 (de) * 1988-04-20 1989-11-09 Asta Pharma Ag Azelastin enthaltende arzneimittel mit kontrollierter wirkstoffabgabe
US5110814A (en) * 1989-01-11 1992-05-05 Asta Pharma Ag Azelastine and its salts used to combat psoriasis
ES2055216T3 (es) * 1989-05-05 1994-08-16 Asta Medica Ag Sales de la azelastina con solubilidad mejorada.
DE4207234A1 (de) * 1992-03-07 1993-09-09 Asta Medica Ag Neue aminocarbonsaeure-derivate mit antiallergischer/antiasthmatischer wirkung und verfahren zu deren herstellung
DE4343409C2 (de) * 1993-12-18 1997-03-20 Asta Medica Ag Verbessertes Verfahren zur Herstellung von Hexahydroazepinonen und Hexahydroazepinolen
DE4345224C2 (de) * 1993-12-18 1999-07-01 Asta Medica Ag Verfahren zur Herstellung von Säureadditionssalzen des Azelastins und Flezelastins
GB2389530B (en) 2002-06-14 2007-01-10 Cipla Ltd Pharmaceutical compositions
US20070020330A1 (en) 2004-11-24 2007-01-25 Medpointe Healthcare Inc. Compositions comprising azelastine and methods of use thereof
DK2522365T3 (en) 2004-11-24 2017-02-06 Meda Pharmaceuticals Inc Compositions comprising azelastine and methods for its use
US8758816B2 (en) 2004-11-24 2014-06-24 Meda Pharmaceuticals Inc. Compositions comprising azelastine and methods of use thereof
DE602007010118D1 (de) * 2006-04-20 2010-12-09 Glaxo Group Ltd 2-substituierte 4-benzylphthalazinonderivate als histamin-h1- und h3-antagonisten

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1046625B (de) * 1957-08-15 1958-12-18 Hydrierwerk Rodleben Veb Verfahren zur Herstellung basisch substituierter Phthalazone
GB1100911A (en) * 1963-08-20 1968-01-24 Benger Lab Ltd Phthalazine derivatives
FR1512879A (fr) * 1966-10-28 1968-02-09 Hydrierwerk Rodleben Veb Procédé pour la fabrication de phtalazones avec substituants basiques

Also Published As

Publication number Publication date
CA1010041A (en) 1977-05-10
SU440838A3 (xx) 1974-08-25
GB1377231A (en) 1974-12-11
DE2164058B2 (de) 1980-10-23
NL177116B (nl) 1985-03-01
SE404604B (sv) 1978-10-16
OA04087A (fr) 1979-10-30
DK136981C (xx) 1978-06-05
NL177116C (nl) 1985-08-01
YU35361B (en) 1980-12-31
FI53704C (fi) 1978-07-10
YU11272A (en) 1980-06-30
NL7200400A (xx) 1972-07-25
IL38496A0 (en) 1972-03-28
PL88930B1 (xx) 1976-10-30
BE778269A (fr) 1972-07-19
FI53704B (xx) 1978-03-31
HU163979B (xx) 1973-12-28
HK62577A (en) 1977-12-30
CH572914A5 (xx) 1976-02-27
DE2164058C3 (de) 1981-08-13
AT313288B (de) 1974-02-11
FR2122517A1 (xx) 1972-09-01
AU3767472A (en) 1973-07-12
DE2164058A1 (de) 1972-07-27
FR2122517B1 (xx) 1975-08-01
DK136981B (da) 1977-12-27
ZA718712B (en) 1972-09-27
ES398949A1 (es) 1975-06-01
AR197293A1 (es) 1974-03-29

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