ZA200907215B - Uses of oligomers of lactic acid in the treatment of gynaecological disorders - Google Patents

Uses of oligomers of lactic acid in the treatment of gynaecological disorders

Info

Publication number
ZA200907215B
ZA200907215B ZA2009/07215A ZA200907215A ZA200907215B ZA 200907215 B ZA200907215 B ZA 200907215B ZA 2009/07215 A ZA2009/07215 A ZA 2009/07215A ZA 200907215 A ZA200907215 A ZA 200907215A ZA 200907215 B ZA200907215 B ZA 200907215B
Authority
ZA
South Africa
Prior art keywords
oligomers
treatment
lactic acid
gynaecological disorders
gynaecological
Prior art date
Application number
ZA2009/07215A
Other languages
English (en)
Inventor
Greg Batcheller
Thomas Hedner
Jörgen Johnson
Werner Schubert
Christer Sjögren
Olov Sterner
Malgorzata Sznitowska
Original Assignee
Laccure Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laccure Ab filed Critical Laccure Ab
Publication of ZA200907215B publication Critical patent/ZA200907215B/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/34—Esters of acyclic saturated polycarboxylic acids having an esterified carboxyl group bound to an acyclic carbon atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/765—Polymers containing oxygen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/02—Suppositories; Bougies; Bases therefor; Ovules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Reproductive Health (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Endocrinology (AREA)
  • Biotechnology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA2009/07215A 2007-03-30 2009-10-15 Uses of oligomers of lactic acid in the treatment of gynaecological disorders ZA200907215B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200700508 2007-03-30
PCT/EP2008/002505 WO2008119518A1 (en) 2007-03-30 2008-03-28 Use of oligomers of lactic acid in the treatment of gynaecological disorders

Publications (1)

Publication Number Publication Date
ZA200907215B true ZA200907215B (en) 2014-03-26

Family

ID=39494560

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA2009/07215A ZA200907215B (en) 2007-03-30 2009-10-15 Uses of oligomers of lactic acid in the treatment of gynaecological disorders

Country Status (19)

Country Link
US (3) US8425894B2 (https=)
EP (2) EP2142186B1 (https=)
JP (2) JP5409596B2 (https=)
KR (1) KR101518014B1 (https=)
CN (2) CN101677980B (https=)
AU (1) AU2008234064B2 (https=)
BR (1) BRPI0809330B8 (https=)
CA (1) CA2681803C (https=)
CY (1) CY1115310T1 (https=)
DK (1) DK2142186T3 (https=)
ES (1) ES2482190T3 (https=)
HR (1) HRP20140559T1 (https=)
MX (1) MX2009010445A (https=)
PL (1) PL2142186T3 (https=)
PT (1) PT2142186E (https=)
RU (1) RU2459620C2 (https=)
SI (1) SI2142186T1 (https=)
WO (1) WO2008119518A1 (https=)
ZA (1) ZA200907215B (https=)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2482190T3 (es) 2007-03-30 2014-08-01 Laccure Ab Uso de oligómeros de ácido láctico en el tratamiento de infecciones ginecológicas
CN101797269B (zh) * 2010-03-23 2012-01-04 杨霞 一种调节女性阴道微生态的生理平衡液
RU2422147C1 (ru) * 2010-03-29 2011-06-27 Государственное образовательное учреждение высшего профессионального образования "Пермская государственная медицинская академия имени академика Е.А. Вагнера Федерального агентства по здравоохранению и социальному развитию" Способ лечения неспецифического аэробного вагинита
WO2012158779A1 (en) 2011-05-17 2012-11-22 Reprotect, Inc. Reusable intravaginal delivery device, system, and method
CN102274333A (zh) * 2011-08-22 2011-12-14 谢英华 一种治疗阴道炎的外洗中药
CN102579829B (zh) * 2012-03-06 2013-09-18 康莉 一种治疗牛放线菌病的中药组合物及其制备方法
EA201590008A1 (ru) 2012-06-13 2015-05-29 Ивофем, Инк. Композиции и способы повышения эффективности бактерицидных средств контрацепции
CN104470498B (zh) * 2012-07-16 2017-08-08 莱克瑞股份公司 含有低聚乳酸的药物组合物
CN102885850B (zh) * 2012-10-15 2013-08-07 山东省医疗器械研究所 一种治疗阴道炎的多孔凝胶颗粒剂
JP2017501227A (ja) 2013-12-19 2017-01-12 エヴォフェム，インク． アルギン酸をベースとする抗菌性化合物を使用して炎症と疾患を阻害するための組成物及び方法
US9895311B2 (en) * 2014-09-25 2018-02-20 Pharmiva Ab Foam-forming compositions and methods for delivering an active to a body cavity
WO2017174731A1 (en) 2016-04-06 2017-10-12 Gedea Biotech Ab Glucono delta-lactone for treatment of vaginal fungal infections
US10249017B2 (en) * 2016-08-11 2019-04-02 Intel Corporation Apparatus and method for shared resource partitioning through credit management
US20190209502A1 (en) * 2016-09-12 2019-07-11 Evofem, Inc. Combination gel for sexually transmitted infections
US11419835B2 (en) 2016-10-04 2022-08-23 Evofem, Inc. Method of treatment and prevention of bacterial vaginosis
CA3040422A1 (en) 2016-10-13 2018-04-19 Catalent U.K. Swindon Zydis Limited Lyophilized pharmaceutical compositions for vaginal delivery
ES2968763T3 (es) * 2018-03-29 2024-05-13 The Materia Company Ltd Formulación intravaginal
CN113423470B (zh) * 2019-02-13 2024-07-09 三吉油脂株式会社 化妆品配合剂、化妆品及其制造方法
WO2023165971A1 (en) 2022-03-01 2023-09-07 Laccure Ab Process for preparation of compositions of oligomers of lactic acid
CN119768161B (zh) * 2023-07-07 2026-04-03 长春圣博玛生物材料有限公司 肌肉萎缩

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4431427A (en) * 1981-10-05 1984-02-14 University Of Delaware Tampons and their manufacture
US5274127A (en) * 1990-09-18 1993-12-28 Biopak Technology, Ltd. Lactide production from dehydration of aqueous lactic acid feed
JP2919912B2 (ja) 1990-05-23 1999-07-19 鐘紡株式会社 修飾プロテアーゼ及びその製造法
US5142023A (en) * 1992-01-24 1992-08-25 Cargill, Incorporated Continuous process for manufacture of lactide polymers with controlled optical purity
JPH07132127A (ja) 1993-06-17 1995-05-23 Mitsui Toatsu Chem Inc 生理用ナプキン
GB9503669D0 (en) 1994-02-24 1995-04-12 Ecological Chem Prod Composition and method for packaging moisture-containing foodstuffs
US5521278A (en) * 1994-08-18 1996-05-28 Ecological Chemical Products Integrated process for the manufacture of lactide
JP2864218B2 (ja) 1994-12-06 1999-03-03 株式会社日本製鋼所 ポリ乳酸共重合体の製造方法
US6369116B1 (en) * 1995-06-02 2002-04-09 Oculex Pharmaceuticals, Inc. Composition and method for treating glaucoma
JPH09227388A (ja) * 1996-02-15 1997-09-02 Naganushi Tetsuaki 大腸癌、食道癌及び乳癌より選ばれた癌に用いる抗悪性腫瘍剤
WO1997045066A1 (en) 1996-05-31 1997-12-04 Uromed Corporation Urinary medical devices
US6229046B1 (en) 1997-10-14 2001-05-08 Cargill, Incorported Lactic acid processing methods arrangements and products
JP2000072680A (ja) * 1998-08-25 2000-03-07 Shiyumeidou:Kk 免疫機能調節剤
JP2001139476A (ja) * 1999-11-15 2001-05-22 Youichirou Naganushi 癌を含めた悪性新生物に用いる抗悪性腫瘍剤
RU2163810C1 (ru) * 2000-05-18 2001-03-10 Майорова Нина Федоровна Состав для удаления доброкачественных новообразований на коже и слизистых и способ его получения
US20040110834A1 (en) * 2001-01-12 2004-06-10 Masahiro Murakami Preventives for microbial infections
EA200300828A1 (ru) 2001-01-24 2003-12-25 Амато Фармасьютикал Продактс, Лтд. Средство против стресса
US20020177624A1 (en) * 2001-03-16 2002-11-28 Calvin Hanna Acetate-lactate buffering vaginal gel and for method of making same and treating bacterial vaginosis
JP2002275256A (ja) * 2001-03-19 2002-09-25 Tendou Seiyaku Kk 乳酸オリゴマーの製造方法
AU2002325614A1 (en) 2001-08-16 2003-03-03 Pharmacon-Forschung Und Beratung Gmbh Compounds containing lactic acid elements, method for the production and use thereof as pharmaceutically active substances
CN1703230A (zh) 2001-11-06 2005-11-30 天藤制药株式会社 含有乳酸寡聚物混合物的抗肿瘤剂
JP2004307561A (ja) 2003-04-02 2004-11-04 Tendou Seiyaku Kk 環状乳酸オリゴマーの製造方法
EA010948B1 (ru) 2003-05-01 2008-12-30 Инноджен Калбиотех Пте Лтд. Фармацевтическая композиция, содержащая лактат, и ее применение
JP4316299B2 (ja) 2003-06-03 2009-08-19 学校法人東海大学 鎖状乳酸オリゴマー誘導体およびその製造方法
JP2005126361A (ja) * 2003-10-23 2005-05-19 Tendou Seiyaku Kk ポリ乳酸混合物を含むマトリックスメタロプロテアーゼ抑制剤
CN1562049A (zh) * 2004-04-02 2005-01-12 聂四平 低聚果糖在制备治疗及预防阴道炎药中的应用
US20050271726A1 (en) * 2004-06-02 2005-12-08 Albert Crum Immune enhancing compositions and methods of use thereof
SE528337C2 (sv) 2004-06-23 2006-10-24 Nestor Medical Ab Sammansättning innefattande mjölksyra och laktoferrin, eller ett peptidfragment därav, och användning av denna sammansättning för behandling av tillstånd i urogenitalsystemet
JP2006232909A (ja) 2005-02-23 2006-09-07 Tokai Univ 環状オリゴ乳酸
JP4431102B2 (ja) 2005-11-11 2010-03-10 キャタピラージャパン株式会社 カウンタウエイト及びカウンタウエイトの製造方法並びに作業機械
RU2308970C1 (ru) * 2006-03-10 2007-10-27 Автономная некоммерческая организация "Институт молекулярной диагностики" (АНО "ИнМоДи") Антибактериальное средство для лечения внутриклеточных инфекций
JP2007258526A (ja) 2006-03-24 2007-10-04 Konica Minolta Holdings Inc 有機エレクトロルミネッセンス素子、及び有機エレクトロルミネッセンスディスプレイ
JP2008157576A (ja) 2006-12-26 2008-07-10 Sharp Corp 加湿機
ES2482190T3 (es) 2007-03-30 2014-08-01 Laccure Ab Uso de oligómeros de ácido láctico en el tratamiento de infecciones ginecológicas

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Publication number Publication date
CN103830216B (zh) 2016-08-17
RU2459620C2 (ru) 2012-08-27
CA2681803C (en) 2014-08-05
CN101677980A (zh) 2010-03-24
BRPI0809330B8 (pt) 2021-05-25
JP2014012675A (ja) 2014-01-23
US20150025142A1 (en) 2015-01-22
US8912232B2 (en) 2014-12-16
CN103830216A (zh) 2014-06-04
US8425894B2 (en) 2013-04-23
CA2681803A1 (en) 2008-10-09
EP2142186A1 (en) 2010-01-13
KR20100016060A (ko) 2010-02-12
PL2142186T3 (pl) 2014-09-30
CY1115310T1 (el) 2017-01-04
EP2142186B1 (en) 2014-04-30
JP5793542B2 (ja) 2015-10-14
PT2142186E (pt) 2014-07-17
DK2142186T3 (da) 2014-08-04
JP2010523480A (ja) 2010-07-15
US9315444B2 (en) 2016-04-19
US20110020265A1 (en) 2011-01-27
JP5409596B2 (ja) 2014-02-05
BRPI0809330A2 (pt) 2014-09-09
US20130317104A1 (en) 2013-11-28
SI2142186T1 (sl) 2014-08-29
AU2008234064B2 (en) 2013-02-07
HRP20140559T1 (hr) 2014-08-01
KR101518014B1 (ko) 2015-05-06
CN101677980B (zh) 2013-10-23
RU2009140141A (ru) 2011-05-10
MX2009010445A (es) 2010-01-29
BRPI0809330B1 (pt) 2019-12-17
AU2008234064A1 (en) 2008-10-09
WO2008119518A1 (en) 2008-10-09
ES2482190T3 (es) 2014-08-01
EP2679222A1 (en) 2014-01-01

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