ZA200903949B - Antibacterial quinoline derivatives - Google Patents
Antibacterial quinoline derivativesInfo
- Publication number
- ZA200903949B ZA200903949B ZA200903949A ZA200903949A ZA200903949B ZA 200903949 B ZA200903949 B ZA 200903949B ZA 200903949 A ZA200903949 A ZA 200903949A ZA 200903949 A ZA200903949 A ZA 200903949A ZA 200903949 B ZA200903949 B ZA 200903949B
- Authority
- ZA
- South Africa
- Prior art keywords
- quinoline derivatives
- antibacterial quinoline
- antibacterial
- derivatives
- quinoline
- Prior art date
Links
- 230000000844 anti-bacterial effect Effects 0.000 title 1
- 229940027991 antiseptic and disinfectant quinoline derivative Drugs 0.000 title 1
- 125000002943 quinolinyl group Chemical class N1=C(C=CC2=CC=CC=C12)* 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Quinoline Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP06125545 | 2006-12-06 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA200903949B true ZA200903949B (en) | 2010-08-25 |
Family
ID=38048032
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200903949A ZA200903949B (en) | 2006-12-06 | 2009-06-05 | Antibacterial quinoline derivatives |
Country Status (34)
Country | Link |
---|---|
US (1) | US20100063026A1 (ru) |
EP (1) | EP2099761B1 (ru) |
JP (1) | JP5466013B2 (ru) |
KR (1) | KR101553600B1 (ru) |
CN (1) | CN101547906B (ru) |
AP (1) | AP2477A (ru) |
AR (1) | AR064148A1 (ru) |
AT (1) | ATE486061T1 (ru) |
AU (1) | AU2007328892B2 (ru) |
BR (1) | BRPI0719915A2 (ru) |
CA (1) | CA2668558C (ru) |
CL (1) | CL2007003518A1 (ru) |
CY (1) | CY1112027T1 (ru) |
DE (1) | DE602007010182D1 (ru) |
DK (1) | DK2099761T3 (ru) |
EA (1) | EA016760B1 (ru) |
ES (1) | ES2354755T3 (ru) |
HK (1) | HK1137437A1 (ru) |
HR (1) | HRP20110024T1 (ru) |
IL (1) | IL199082A (ru) |
JO (1) | JO2683B1 (ru) |
ME (1) | ME01230B (ru) |
MX (1) | MX2009005906A (ru) |
MY (1) | MY145940A (ru) |
NO (1) | NO341984B1 (ru) |
NZ (1) | NZ576862A (ru) |
PL (1) | PL2099761T3 (ru) |
PT (1) | PT2099761E (ru) |
RS (1) | RS51582B (ru) |
SI (1) | SI2099761T1 (ru) |
TW (1) | TWI487526B (ru) |
UA (1) | UA101307C2 (ru) |
WO (1) | WO2008068272A2 (ru) |
ZA (1) | ZA200903949B (ru) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JO2970B1 (en) * | 2006-12-06 | 2016-03-15 | جانسين فارماسوتيكا ان. في | Quinoline antibacterial derivatives |
ES2576491T3 (es) * | 2012-04-27 | 2016-07-07 | Janssen Pharmaceutica, N.V. | Derivados de quinolina antibacterianos |
MX358506B (es) | 2012-04-27 | 2018-08-22 | Janssen Pharmaceutica Nv | Derivados de quinolina antibacterianos. |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2001503411A (ja) * | 1996-10-28 | 2001-03-13 | ディパートメント オブ ジ アーミー,ユー.エス.ガバメント | 抗生物質耐性感染症の処置のための化合物、組成物および方法 |
DK2301544T3 (da) * | 2002-07-25 | 2013-01-02 | Janssen Pharmaceutica Nv | Quinolinderivater som mellemprodukter til mykobakterielle inhibitorer |
DE602005016890D1 (de) * | 2004-01-23 | 2009-11-12 | Janssen Pharmaceutica Nv | Chinolinderivate und ihre verwendung als mycobakterielle inhibitoren |
EP1713776B1 (en) * | 2004-01-29 | 2008-05-14 | Janssen Pharmaceutica N.V. | Quinoline derivatives for use as mycobacterial inhibitors |
MXPA06013888A (es) * | 2004-05-28 | 2007-01-26 | Janssen Pharmaceutica Nv | Uso de derivados de quinolina sustituidos para el tratamiento de enfermedades micobacterianas resistentes a los farmacos. |
EE05394B1 (et) * | 2004-12-24 | 2011-04-15 | Janssen Pharmaceutica N.V. | Kinoliinihendid kasutamiseks latentse tuberkuloosi ravis |
EE05697B1 (et) * | 2005-06-08 | 2014-02-17 | Janssen Pharmaceutica N.V. | Kinoliini derivaadid kui antibakteriaalsed toimeained |
JO2752B1 (en) * | 2005-06-28 | 2014-03-15 | شركة جانسين فارماسوتيكا ان. في | Quinoline derivatives acting as antibacterial agents |
UA88701C2 (ru) * | 2005-06-28 | 2009-11-10 | Янссэн Фармацэвтика Н.В. | Производные хинолина как антибактериальные агенты |
JO2952B1 (en) * | 2005-08-03 | 2016-03-15 | جانسين فارماسوتيكا ان. في | Quinoline derivatives acting as antibacterial agents |
JO2855B1 (en) * | 2005-08-03 | 2015-03-15 | شركة جانسين فارماسوتيكا ان. في | Quinoline derivatives acting as antibacterial agents |
JO2837B1 (en) * | 2005-08-03 | 2014-09-15 | جانسن فارمسيتكا ان في | Quinoline derivatives acting as antibacterial agents |
-
2007
- 2007-12-02 JO JO2007510A patent/JO2683B1/en active
- 2007-12-04 BR BRPI0719915-5A2A patent/BRPI0719915A2/pt not_active Application Discontinuation
- 2007-12-04 AT AT07847817T patent/ATE486061T1/de active
- 2007-12-04 ME MEP-2011-10A patent/ME01230B/me unknown
- 2007-12-04 UA UAA200904443A patent/UA101307C2/ru unknown
- 2007-12-04 EP EP07847817A patent/EP2099761B1/en active Active
- 2007-12-04 PL PL07847817T patent/PL2099761T3/pl unknown
- 2007-12-04 ES ES07847817T patent/ES2354755T3/es active Active
- 2007-12-04 NZ NZ576862A patent/NZ576862A/en unknown
- 2007-12-04 JP JP2009539742A patent/JP5466013B2/ja active Active
- 2007-12-04 WO PCT/EP2007/063319 patent/WO2008068272A2/en active Application Filing
- 2007-12-04 DE DE602007010182T patent/DE602007010182D1/de active Active
- 2007-12-04 PT PT07847817T patent/PT2099761E/pt unknown
- 2007-12-04 CA CA2668558A patent/CA2668558C/en active Active
- 2007-12-04 EA EA200970537A patent/EA016760B1/ru unknown
- 2007-12-04 RS RS20110019A patent/RS51582B/en unknown
- 2007-12-04 MX MX2009005906A patent/MX2009005906A/es active IP Right Grant
- 2007-12-04 CN CN200780045128.8A patent/CN101547906B/zh active Active
- 2007-12-04 US US12/516,420 patent/US20100063026A1/en not_active Abandoned
- 2007-12-04 DK DK07847817.9T patent/DK2099761T3/da active
- 2007-12-04 MY MYPI20092287A patent/MY145940A/en unknown
- 2007-12-04 SI SI200730471T patent/SI2099761T1/sl unknown
- 2007-12-04 AU AU2007328892A patent/AU2007328892B2/en active Active
- 2007-12-04 KR KR1020097013568A patent/KR101553600B1/ko active IP Right Review Request
- 2007-12-04 AP AP2009004873A patent/AP2477A/xx active
- 2007-12-05 CL CL200703518A patent/CL2007003518A1/es unknown
- 2007-12-05 AR ARP070105441A patent/AR064148A1/es unknown
- 2007-12-05 TW TW096146212A patent/TWI487526B/zh active
-
2009
- 2009-06-02 IL IL199082A patent/IL199082A/en active IP Right Grant
- 2009-06-05 ZA ZA200903949A patent/ZA200903949B/xx unknown
- 2009-07-06 NO NO20092541A patent/NO341984B1/no unknown
-
2010
- 2010-02-03 HK HK10101151.1A patent/HK1137437A1/xx unknown
-
2011
- 2011-01-13 HR HR20110024T patent/HRP20110024T1/hr unknown
- 2011-01-27 CY CY20111100087T patent/CY1112027T1/el unknown
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